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The map label for this gene is ykvZ

Identifier: 16078451

GI number: 16078451

Start: 1455064

End: 1456029

Strand: Direct

Name: ykvZ

Synonym: BSU13870

Alternate gene names: 16078451

Gene position: 1455064-1456029 (Clockwise)

Preceding gene: 16078450

Following gene: 255767321

Centisome position: 34.52

GC content: 44.0

Gene sequence:

>966_bases
ATGGCTAATATTAAAGACATTGCAGAGAAAGCCGGTGTCTCTGTTACAACGGTTTCCCGAGTCATAAACAATCATCCATA
CGTCAGTGAAGACAAACGAAAAAGAGTGTTTGAGGCAATGGAATCATTGGAGTACACGAGAAATATTCACGCTGTACATT
TGTCGAAAGGATTTTCAAACATGATTGGTGTTGTCTTGCCGACGGTTAATCTGCCATATTTTGCAGAGCTGATTGCAGGA
ATAGCCGACGCAGCCGCGGAATCCGGGGTTCACCTCTCTTTATTCCAAACAAACTATGAAGTACAAAAAGAAATCTTTGC
GCTGTCCCAATTAAAGCAGCGCCAGGTTGACGGCCTGATTTTTTGCTCAAAGGCGCTTGCTGATGAGAAACTCATGGAAT
GGGAGGGCCCGATTTTGCTTTGCCAGAATTCAGATAATGCCCGCTTCCCAACCATCAGCATTCCTCACCAAGAAGCATTT
CGGAACGGCTTGGACTATTTAATTGCCAAAGGGCACAAAAAAATAGCCATCTGTTTGGCAAGAAAAAAAGGCATGAACAG
CCATTTTCGAATCAAAGCCTACAAAGAGGCATTGGAAGAGATCGGCGAGGCATTTCGTGAAGACTGGGTAATTGAGAAAG
CGATTACAATCAATGATGGGAAGGCGCTTTTTCATAAATGGAATACGTGGAAGGAAAAGCCGACGGCTATTTTTGTTGCC
AATGACCAAGTCTCAGCAGGGCTTTTTCTTGAAGCAAAGAACCAGCGGGTGTCAGTACCGGATGAGCTTGCAATCTTAAG
CGTTGATAACCACGAAATCAGCCAAGCGCTTGGAATCACAACGATCGATATTCAGACAAGGGAAATGGGAAAGCAGGCAT
TTGCCATATTGGAAAAAAGAATTCAAGGACAGCCGATTGAAAGGAAAGTTCTGGATTACCGTCTCATCGAAAGATCGACT
GTTTAG

Upstream 100 bases:

>100_bases
TTCTCCTTTCAGCTAAAAACACAAAAAGATATCTGGTACGTCCATATCATATTGTATGAAACGCATTCCAGATCAAGGGG
ATTTAGAAAGAAGGGAATCT

Downstream 100 bases:

>100_bases
TGAATGCATTGAAAAAAGGTTTGACGTGCATTCTGTTCGTTATGTACGATATGAGGTATTGAATGACAAAGGAGCTGAGG
ATCGTGAATGGGTCCTTCAC

Product: LacI family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 321; Mature: 320

Protein sequence:

>321_residues
MANIKDIAEKAGVSVTTVSRVINNHPYVSEDKRKRVFEAMESLEYTRNIHAVHLSKGFSNMIGVVLPTVNLPYFAELIAG
IADAAAESGVHLSLFQTNYEVQKEIFALSQLKQRQVDGLIFCSKALADEKLMEWEGPILLCQNSDNARFPTISIPHQEAF
RNGLDYLIAKGHKKIAICLARKKGMNSHFRIKAYKEALEEIGEAFREDWVIEKAITINDGKALFHKWNTWKEKPTAIFVA
NDQVSAGLFLEAKNQRVSVPDELAILSVDNHEISQALGITTIDIQTREMGKQAFAILEKRIQGQPIERKVLDYRLIERST
V

Sequences:

>Translated_321_residues
MANIKDIAEKAGVSVTTVSRVINNHPYVSEDKRKRVFEAMESLEYTRNIHAVHLSKGFSNMIGVVLPTVNLPYFAELIAG
IADAAAESGVHLSLFQTNYEVQKEIFALSQLKQRQVDGLIFCSKALADEKLMEWEGPILLCQNSDNARFPTISIPHQEAF
RNGLDYLIAKGHKKIAICLARKKGMNSHFRIKAYKEALEEIGEAFREDWVIEKAITINDGKALFHKWNTWKEKPTAIFVA
NDQVSAGLFLEAKNQRVSVPDELAILSVDNHEISQALGITTIDIQTREMGKQAFAILEKRIQGQPIERKVLDYRLIERST
V
>Mature_320_residues
ANIKDIAEKAGVSVTTVSRVINNHPYVSEDKRKRVFEAMESLEYTRNIHAVHLSKGFSNMIGVVLPTVNLPYFAELIAGI
ADAAAESGVHLSLFQTNYEVQKEIFALSQLKQRQVDGLIFCSKALADEKLMEWEGPILLCQNSDNARFPTISIPHQEAFR
NGLDYLIAKGHKKIAICLARKKGMNSHFRIKAYKEALEEIGEAFREDWVIEKAITINDGKALFHKWNTWKEKPTAIFVAN
DQVSAGLFLEAKNQRVSVPDELAILSVDNHEISQALGITTIDIQTREMGKQAFAILEKRIQGQPIERKVLDYRLIERSTV

Specific function: This Protein Negatively Controls The Transcription Initiation Of Genes Such As Deocabd, Udp, And Cdd Encoding Catabolizing Enzymes And Nupc, Nupg, And Tsx Encoding Transporting And Pore-Forming Proteins. Binds Cytidine And Adenosine As Effectors. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain

Homologues:

Organism=Escherichia coli, GI1790369, Length=329, Percent_Identity=28.2674772036474, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI1790194, Length=330, Percent_Identity=28.1818181818182, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1787948, Length=336, Percent_Identity=28.2738095238095, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1788474, Length=299, Percent_Identity=27.4247491638796, Blast_Score=111, Evalue=6e-26,
Organism=Escherichia coli, GI1789202, Length=329, Percent_Identity=27.0516717325228, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI1787580, Length=323, Percent_Identity=26.9349845201238, Blast_Score=107, Evalue=7e-25,
Organism=Escherichia coli, GI48994940, Length=315, Percent_Identity=27.3015873015873, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1786540, Length=339, Percent_Identity=27.7286135693215, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1789068, Length=302, Percent_Identity=26.158940397351, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1787906, Length=219, Percent_Identity=28.310502283105, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1789456, Length=314, Percent_Identity=22.9299363057325, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790715, Length=317, Percent_Identity=20.5047318611987, Blast_Score=65, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YKVZ_BACSU (O31690)

Other databases:

- EMBL:   AL009126
- PIR:   H69869
- RefSeq:   NP_389270.1
- ProteinModelPortal:   O31690
- SMR:   O31690
- EnsemblBacteria:   EBBACT00000003028
- GeneID:   936232
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU13870
- NMPDR:   fig|224308.1.peg.1389
- GenoList:   BSU13870
- GeneTree:   EBGT00070000031978
- HOGENOM:   HBG753640
- OMA:   LIERSTV
- ProtClustDB:   CLSK887206
- BioCyc:   BSUB:BSU13870-MONOMER
- GO:   GO:0005622
- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761
- PRINTS:   PR00036
- SMART:   SM00354

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1; SSF47413 Lambda_like_DNA

EC number: NA

Molecular weight: Translated: 36192; Mature: 36061

Theoretical pI: Translated: 7.69; Mature: 7.69

Prosite motif: PS00356 HTH_LACI_1; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANIKDIAEKAGVSVTTVSRVINNHPYVSEDKRKRVFEAMESLEYTRNIHAVHLSKGFSN
CCCHHHHHHHHCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCEEEEEECCCHHH
MIGVVLPTVNLPYFAELIAGIADAAAESGVHLSLFQTNYEVQKEIFALSQLKQRQVDGLI
HHHHHCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHCCHHE
FCSKALADEKLMEWEGPILLCQNSDNARFPTISIPHQEAFRNGLDYLIAKGHKKIAICLA
EEHHHHHHHHHHHCCCCEEEEECCCCCCCCEEECCHHHHHHCCHHHHHHCCCCEEEEEEE
RKKGMNSHFRIKAYKEALEEIGEAFREDWVIEKAITINDGKALFHKWNTWKEKPTAIFVA
HHCCCCCCEEHHHHHHHHHHHHHHHHHCCEEEEEEEECCCHHHHEECCCCCCCCCEEEEE
NDQVSAGLFLEAKNQRVSVPDELAILSVDNHEISQALGITTIDIQTREMGKQAFAILEKR
CCCCCCCEEEEECCCCCCCCCCEEEEEECCHHHHHHHCEEEEEEEHHHHHHHHHHHHHHH
IQGQPIERKVLDYRLIERSTV
HCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ANIKDIAEKAGVSVTTVSRVINNHPYVSEDKRKRVFEAMESLEYTRNIHAVHLSKGFSN
CCHHHHHHHHCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCEEEEEECCCHHH
MIGVVLPTVNLPYFAELIAGIADAAAESGVHLSLFQTNYEVQKEIFALSQLKQRQVDGLI
HHHHHCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHCCHHE
FCSKALADEKLMEWEGPILLCQNSDNARFPTISIPHQEAFRNGLDYLIAKGHKKIAICLA
EEHHHHHHHHHHHCCCCEEEEECCCCCCCCEEECCHHHHHHCCHHHHHHCCCCEEEEEEE
RKKGMNSHFRIKAYKEALEEIGEAFREDWVIEKAITINDGKALFHKWNTWKEKPTAIFVA
HHCCCCCCEEHHHHHHHHHHHHHHHHHCCEEEEEEEECCCHHHHEECCCCCCCCCEEEEE
NDQVSAGLFLEAKNQRVSVPDELAILSVDNHEISQALGITTIDIQTREMGKQAFAILEKR
CCCCCCCEEEEECCCCCCCCCCEEEEEECCHHHHHHHCEEEEEEEHHHHHHHHHHHHHHH
IQGQPIERKVLDYRLIERSTV
HCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377