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The map label for this gene is queC

Identifier: 16078436

GI number: 16078436

Start: 1439448

End: 1440107

Strand: Direct

Name: queC

Synonym: BSU13720

Alternate gene names: 16078436

Gene position: 1439448-1440107 (Clockwise)

Preceding gene: 16078435

Following gene: 16078437

Centisome position: 34.15

GC content: 45.0

Gene sequence:

>660_bases
ATGAAAAAAGAAAAAGCAATTGTCGTATTTAGCGGCGGTCAAGACAGCACAACATGCTTACTGTGGGCCTTAAAAGAATT
CGAAGAAGTCGAAACGGTGACTTTTCATTATAATCAGCGACATTCGCAGGAAGTTGAAGTGGCAAAATCCATTGCGGAAA
AGCTTGGTGTGAAAAATCATTTGCTTGATATGTCACTTTTAAATCAGCTTGCACCGAATGCCCTGACTAGAAATGATATT
GAGATAGAAGTAAAAGACGGCGAACTGCCATCCACATTCGTTCCAGGCCGCAATTTGGTATTCTTATCCTTTGCGTCTAT
CCTGGCTTACCAAATTGGCGCGCGCCACATTATTACAGGAGTTTGCGAGACAGACTTCAGTGGTTATCCTGACTGCCGTG
ACGAATTCGTGAAATCTTGCAATGTCACGGTAAATCTGGCAATGGAGAAGCCGTTTGTGATCCACACGCCTCTCATGTGG
CTCAATAAGGCGGAAACGTGGAAGCTTGCAGATGAGCTTGGCGCGCTGGATTTTGTGAAAAACAACACGCTGACATGCTA
TAACGGCATCATCGCAGACGGCTGCGGCGAATGTCCGGCATGTCACCTTCGTTCAAAAGGTTATGAAGAATATATGGTGA
TGAAAGGAGAGCGTGCATAA

Upstream 100 bases:

>100_bases
GTTTTTCTAGAGCACCTTCCGAAAAAAGGTGTTTTTTTGCGTGAATTAGCTGTAGCGATGTCTCTCGCCGGCGTTTTTAT
TGCGGAGAAGGAGAGGAATC

Downstream 100 bases:

>100_bases
ATTGTTATCTCAAATTTATCCGCAGGCCCAGCATCCTTATTCGTTTGAACTGAATAAGGACATGCATATCTCAGCCGCTC
ATTTTATCCCTCGGGAAAGT

Product: pre-queuosine 0 synthase

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine synthase; PreQ(0) synthase; Queuosine biosynthesis protein queC [H]

Number of amino acids: Translated: 219; Mature: 219

Protein sequence:

>219_residues
MKKEKAIVVFSGGQDSTTCLLWALKEFEEVETVTFHYNQRHSQEVEVAKSIAEKLGVKNHLLDMSLLNQLAPNALTRNDI
EIEVKDGELPSTFVPGRNLVFLSFASILAYQIGARHIITGVCETDFSGYPDCRDEFVKSCNVTVNLAMEKPFVIHTPLMW
LNKAETWKLADELGALDFVKNNTLTCYNGIIADGCGECPACHLRSKGYEEYMVMKGERA

Sequences:

>Translated_219_residues
MKKEKAIVVFSGGQDSTTCLLWALKEFEEVETVTFHYNQRHSQEVEVAKSIAEKLGVKNHLLDMSLLNQLAPNALTRNDI
EIEVKDGELPSTFVPGRNLVFLSFASILAYQIGARHIITGVCETDFSGYPDCRDEFVKSCNVTVNLAMEKPFVIHTPLMW
LNKAETWKLADELGALDFVKNNTLTCYNGIIADGCGECPACHLRSKGYEEYMVMKGERA
>Mature_219_residues
MKKEKAIVVFSGGQDSTTCLLWALKEFEEVETVTFHYNQRHSQEVEVAKSIAEKLGVKNHLLDMSLLNQLAPNALTRNDI
EIEVKDGELPSTFVPGRNLVFLSFASILAYQIGARHIITGVCETDFSGYPDCRDEFVKSCNVTVNLAMEKPFVIHTPLMW
LNKAETWKLADELGALDFVKNNTLTCYNGIIADGCGECPACHLRSKGYEEYMVMKGERA

Specific function: Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) [H]

COG id: COG0603

COG function: function code R; Predicted PP-loop superfamily ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the queC family [H]

Homologues:

Organism=Escherichia coli, GI1786648, Length=216, Percent_Identity=57.4074074074074, Blast_Score=265, Evalue=1e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018317
- InterPro:   IPR014729 [H]

Pfam domain/function: PF06508 ExsB [H]

EC number: NA

Molecular weight: Translated: 24529; Mature: 24529

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
3.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKEKAIVVFSGGQDSTTCLLWALKEFEEVETVTFHYNQRHSQEVEVAKSIAEKLGVKNH
CCCCCEEEEEECCCCCHHHHHHHHHHHHHHEEEEEEECCCCCHHHHHHHHHHHHHCHHHH
LLDMSLLNQLAPNALTRNDIEIEVKDGELPSTFVPGRNLVFLSFASILAYQIGARHIITG
HHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHEEE
VCETDFSGYPDCRDEFVKSCNVTVNLAMEKPFVIHTPLMWLNKAETWKLADELGALDFVK
ECCCCCCCCCCHHHHHHHHCCEEEEEEECCCEEEECCHHHCCCCCHHHHHHHHCCCEECC
NNTLTCYNGIIADGCGECPACHLRSKGYEEYMVMKGERA
CCEEEEECCEEECCCCCCCCHHHCCCCCCEEEEECCCCC
>Mature Secondary Structure
MKKEKAIVVFSGGQDSTTCLLWALKEFEEVETVTFHYNQRHSQEVEVAKSIAEKLGVKNH
CCCCCEEEEEECCCCCHHHHHHHHHHHHHHEEEEEEECCCCCHHHHHHHHHHHHHCHHHH
LLDMSLLNQLAPNALTRNDIEIEVKDGELPSTFVPGRNLVFLSFASILAYQIGARHIITG
HHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHEEE
VCETDFSGYPDCRDEFVKSCNVTVNLAMEKPFVIHTPLMWLNKAETWKLADELGALDFVK
ECCCCCCCCCCHHHHHHHHCCEEEEEEECCCEEEECCHHHCCCCCHHHHHHHHCCCEECC
NNTLTCYNGIIADGCGECPACHLRSKGYEEYMVMKGERA
CCEEEEECCEEECCCCCCCCHHHCCCCCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA