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The map label for this gene is rsbRB

Identifier: 16078385

GI number: 16078385

Start: 1387206

End: 1388039

Strand: Direct

Name: rsbRB

Synonym: BSU13200

Alternate gene names: 16078385

Gene position: 1387206-1388039 (Clockwise)

Preceding gene: 255767310

Following gene: 16078390

Centisome position: 32.91

GC content: 41.25

Gene sequence:

>834_bases
ATGAAACTGAATGAAAAATTATATGCATTTTTTTCAGAGCATGTGGAACAAATGGCCGAGGAATGGATTGAAACGATGGA
GGAAAGTGATCCGAATTCGCTTTACGCCCTACATAATGCAACAGTAACGGAAGAATTGAAAGAGCAGGACAGAGAATTTT
ACCGGCATCTGAATTACATGTATGTTTTACCGGAAAAACAATTTCTCGAAGAGTTTCAAGAGTGGGTCATTGAGCTGACC
AACGATCAAAAACATCTCGACACACCGGTTCAGTATGTCATTCGGGAGTTTATGAGAAACAGGAGATTATATACGAAGTA
TTTTGAGAAGTTCGCAGAAGAAAATGAATCAGCGTTTGAACCGGGAGAGAAGCAAAAATGGGCAGATTTGATTGTAAAAG
TATTTGATTTCACCATTTATACATTCGTTGATCACGCTGAAATGAATGCCAAGCAGCAATTAAACGCCCAAAGAGAAATG
ATATTGGAATTAAGCTCACCTGTCATTACCCTGAGCAAATCAACAGCTCTGCTGCCGCTTGTCGGTGACATTGATACCGA
ACGGGCGAAGTTTATTCTGGAAAACACGCTTCAAGCTTGTGCGAAAAGACGTGTGGAGCATCTGTTAATCGATCTGTCAG
GTGTTGTTGTGGTGGATACGATGGTGGCGCACCAGATCTTTAAATTGATTGAGGCGCTTAATCTGATCGGTGTCCGGTCA
ACCCTGTCAGGAATCAGGCCTGAAATTGCGCAAACTGCTGTACAGCTGGGGATTGACTTTTCGAATATTACTATTAAAAC
CAACCTTGCCCAAGCATTAAACTATCATCAATAA

Upstream 100 bases:

>100_bases
AAGAATTAGTAATCTTCAAAATATTGGATGGCTTCAACATGTATGACTGGGATTCAACTGTAAGTCAAGTTATAATAGTG
TTGGGGAAAGGAGCAGTGTC

Downstream 100 bases:

>100_bases
AAAAATCCGCTATCTGTGATAGCGGATTTTTTATGATGCGAAACATAAAGATACGAGAAAGGATCCCGCGAATAATAAGA
GGACGAGGCAAAAGAACACC

Product: piezosome protein

Products: NA

Alternate protein names: Stressosome protein rsbRB

Number of amino acids: Translated: 277; Mature: 277

Protein sequence:

>277_residues
MKLNEKLYAFFSEHVEQMAEEWIETMEESDPNSLYALHNATVTEELKEQDREFYRHLNYMYVLPEKQFLEEFQEWVIELT
NDQKHLDTPVQYVIREFMRNRRLYTKYFEKFAEENESAFEPGEKQKWADLIVKVFDFTIYTFVDHAEMNAKQQLNAQREM
ILELSSPVITLSKSTALLPLVGDIDTERAKFILENTLQACAKRRVEHLLIDLSGVVVVDTMVAHQIFKLIEALNLIGVRS
TLSGIRPEIAQTAVQLGIDFSNITIKTNLAQALNYHQ

Sequences:

>Translated_277_residues
MKLNEKLYAFFSEHVEQMAEEWIETMEESDPNSLYALHNATVTEELKEQDREFYRHLNYMYVLPEKQFLEEFQEWVIELT
NDQKHLDTPVQYVIREFMRNRRLYTKYFEKFAEENESAFEPGEKQKWADLIVKVFDFTIYTFVDHAEMNAKQQLNAQREM
ILELSSPVITLSKSTALLPLVGDIDTERAKFILENTLQACAKRRVEHLLIDLSGVVVVDTMVAHQIFKLIEALNLIGVRS
TLSGIRPEIAQTAVQLGIDFSNITIKTNLAQALNYHQ
>Mature_277_residues
MKLNEKLYAFFSEHVEQMAEEWIETMEESDPNSLYALHNATVTEELKEQDREFYRHLNYMYVLPEKQFLEEFQEWVIELT
NDQKHLDTPVQYVIREFMRNRRLYTKYFEKFAEENESAFEPGEKQKWADLIVKVFDFTIYTFVDHAEMNAKQQLNAQREM
ILELSSPVITLSKSTALLPLVGDIDTERAKFILENTLQACAKRRVEHLLIDLSGVVVVDTMVAHQIFKLIEALNLIGVRS
TLSGIRPEIAQTAVQLGIDFSNITIKTNLAQALNYHQ

Specific function: Negative regulator of sigma-B activity. Non- phosphorylated rsbS binds to rsbT, preventing its association with rsbU. Requires any one of rsbRA, rsbRB, rsbRC or rsbRD to sequester rsbT. When rsbS and the rsbR paralog(s) are phosphorylated, they release rs

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RSBRB_BACSU (O34860)

Other databases:

- EMBL:   AJ002571
- EMBL:   AL009126
- PIR:   G69646
- RefSeq:   NP_389203.1
- ProteinModelPortal:   O34860
- SMR:   O34860
- PhosSite:   O34860
- EnsemblBacteria:   EBBACT00000002730
- GeneID:   938160
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU13200
- NMPDR:   fig|224308.1.peg.1322
- GenoList:   BSU13200
- GeneTree:   EBGT00050000000143
- HOGENOM:   HBG338610
- OMA:   QREMILE
- ProtClustDB:   CLSK887169
- BioCyc:   BSUB:BSU13200-MONOMER
- InterPro:   IPR002645
- Gene3D:   G3DSA:3.30.750.24

Pfam domain/function: PF01740 STAS; SSF52091 STAS

EC number: NA

Molecular weight: Translated: 32387; Mature: 32387

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLNEKLYAFFSEHVEQMAEEWIETMEESDPNSLYALHNATVTEELKEQDREFYRHLNYM
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHHCCCE
YVLPEKQFLEEFQEWVIELTNDQKHLDTPVQYVIREFMRNRRLYTKYFEKFAEENESAFE
EECCCHHHHHHHHHHHHHHCCCCHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCC
PGEKQKWADLIVKVFDFTIYTFVDHAEMNAKQQLNAQREMILELSSPVITLSKSTALLPL
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCEEEECCCCEEEEE
VGDIDTERAKFILENTLQACAKRRVEHLLIDLSGVVVVDTMVAHQIFKLIEALNLIGVRS
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
TLSGIRPEIAQTAVQLGIDFSNITIKTNLAQALNYHQ
HHHHCCHHHHHHHHHHCCCHHCEEEEHHHHHHCCCCC
>Mature Secondary Structure
MKLNEKLYAFFSEHVEQMAEEWIETMEESDPNSLYALHNATVTEELKEQDREFYRHLNYM
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHHCCCE
YVLPEKQFLEEFQEWVIELTNDQKHLDTPVQYVIREFMRNRRLYTKYFEKFAEENESAFE
EECCCHHHHHHHHHHHHHHCCCCHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCC
PGEKQKWADLIVKVFDFTIYTFVDHAEMNAKQQLNAQREMILELSSPVITLSKSTALLPL
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCEEEECCCCEEEEE
VGDIDTERAKFILENTLQACAKRRVEHLLIDLSGVVVVDTMVAHQIFKLIEALNLIGVRS
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
TLSGIRPEIAQTAVQLGIDFSNITIKTNLAQALNYHQ
HHHHCCHHHHHHHHHHCCCHHCEEEEHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 11157946