Click here to switch to the map view.

The map label for this gene is exuR

Identifier: 16078302

GI number: 16078302

Start: 1308802

End: 1309803

Strand: Direct

Name: exuR

Synonym: BSU12370

Alternate gene names: 16078302

Gene position: 1308802-1309803 (Clockwise)

Preceding gene: 16078301

Following gene: 16078303

Centisome position: 31.05

GC content: 43.81

Gene sequence:

>1002_bases
ATGGTAACCATAAAAGATATCGCAAAACTCGCAAACGTATCCCACACTACTGTTTCCAGAGCACTCAACAACAGCCCTTA
CATCAAAGAACATACGAAGAAAAAAATATTAGAGCTAGCAGAGCAGCTCAACTATACACCAAATGTAAATGCGAAAAGTC
TGGCGATGCAAAAGTCGCATACGATCGGGCTATTCTTTACAAGCATTACAAACGGAACCTCACACAGCTTCTTTGCAGAC
ACTATCAAAGGCGTCAATCAAGCCATAAGTGAGGATTACAATCTGTATGTGCGCGGCATTGATGATCTGAAAAACTATGA
CTCCGTTACACCGATGAGATATGACGGCATCATTTTAATGAGCCAAAGTGACATTGATAATTCTTTTATTTACCATATTC
GCGAAAAAAACATTCCGCTTGTCGTGCTGAATCGTGATATTGATGATCGTACCATCACGAATATTTTGTCCAATGACAAG
GAAGGCTCTCAAGAAGCTGTAGAATACTTCATTCAGTCCGGACATCAAGACATCGCCATCATCGAGGGGATCGAAGGCTT
TAAATCCTCCCAGCAGCGAAAGGAAGGGTACTTATCCGCACTGATTCAACATCATATTCCGATCAAGCATGAATACAGTG
TCAAAGGACAGTACGATATGGAAAGCGGCTTTCAAGCGATGGAGCGGCTGCTGGCACTGCCGAATCCTCCAACCGCTGTT
TTTTGTTCGAATGATGACATGGCAATCGGAGCGATGAATGCGATATTCGCAAAGGGCCTGCGCGTTCCTGATGATATTTC
GGTGATCGGGTTTGATGATATTGGGTTTTCACAGTACATCACGCCAAGGCTTTCAACAGTAAAGCGCCCAGTGGAGAAAA
TAAGCGTGCTCGGTGCGCAAAAACTCTTGTCGCTGATCAGCGAGCCCGAAACAAAAGCAGAAAAAATCTTGGAAAACACA
GAATTTATGGTGCGTGATTCAGTCAGACGATTGACGACGTGA

Upstream 100 bases:

>100_bases
TGTGTCTTATTAATCTGGAAATATAGTGGGAGAGGCGGTATGTTTGATGATACAATATACAGTAAATAATCGCAGCCGGT
ATGATAAGGAAGGGAATTAG

Downstream 100 bases:

>100_bases
TGTCCCGTTTTTCAGCGGGCATTCTTTATACAGAAAAATGTTAACGTGTGCATAAAGTGAGAGGGAGGCAATAAGGGTGC
AGAAGCTGAATAAAAATGTG

Product: LacI family transcriptional regulator

Products: NA

Alternate protein names: Probable galacturonate locus repressor

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MVTIKDIAKLANVSHTTVSRALNNSPYIKEHTKKKILELAEQLNYTPNVNAKSLAMQKSHTIGLFFTSITNGTSHSFFAD
TIKGVNQAISEDYNLYVRGIDDLKNYDSVTPMRYDGIILMSQSDIDNSFIYHIREKNIPLVVLNRDIDDRTITNILSNDK
EGSQEAVEYFIQSGHQDIAIIEGIEGFKSSQQRKEGYLSALIQHHIPIKHEYSVKGQYDMESGFQAMERLLALPNPPTAV
FCSNDDMAIGAMNAIFAKGLRVPDDISVIGFDDIGFSQYITPRLSTVKRPVEKISVLGAQKLLSLISEPETKAEKILENT
EFMVRDSVRRLTT

Sequences:

>Translated_333_residues
MVTIKDIAKLANVSHTTVSRALNNSPYIKEHTKKKILELAEQLNYTPNVNAKSLAMQKSHTIGLFFTSITNGTSHSFFAD
TIKGVNQAISEDYNLYVRGIDDLKNYDSVTPMRYDGIILMSQSDIDNSFIYHIREKNIPLVVLNRDIDDRTITNILSNDK
EGSQEAVEYFIQSGHQDIAIIEGIEGFKSSQQRKEGYLSALIQHHIPIKHEYSVKGQYDMESGFQAMERLLALPNPPTAV
FCSNDDMAIGAMNAIFAKGLRVPDDISVIGFDDIGFSQYITPRLSTVKRPVEKISVLGAQKLLSLISEPETKAEKILENT
EFMVRDSVRRLTT
>Mature_333_residues
MVTIKDIAKLANVSHTTVSRALNNSPYIKEHTKKKILELAEQLNYTPNVNAKSLAMQKSHTIGLFFTSITNGTSHSFFAD
TIKGVNQAISEDYNLYVRGIDDLKNYDSVTPMRYDGIILMSQSDIDNSFIYHIREKNIPLVVLNRDIDDRTITNILSNDK
EGSQEAVEYFIQSGHQDIAIIEGIEGFKSSQQRKEGYLSALIQHHIPIKHEYSVKGQYDMESGFQAMERLLALPNPPTAV
FCSNDDMAIGAMNAIFAKGLRVPDDISVIGFDDIGFSQYITPRLSTVKRPVEKISVLGAQKLLSLISEPETKAEKILENT
EFMVRDSVRRLTT

Specific function: Transcriptional repressor for the exu locus which is required for galacturonate utilization (Probable)

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain

Homologues:

Organism=Escherichia coli, GI1787948, Length=336, Percent_Identity=31.8452380952381, Blast_Score=180, Evalue=1e-46,
Organism=Escherichia coli, GI1790194, Length=334, Percent_Identity=31.7365269461078, Blast_Score=179, Evalue=2e-46,
Organism=Escherichia coli, GI1790369, Length=337, Percent_Identity=30.2670623145401, Blast_Score=160, Evalue=9e-41,
Organism=Escherichia coli, GI1789068, Length=305, Percent_Identity=32.1311475409836, Blast_Score=157, Evalue=7e-40,
Organism=Escherichia coli, GI1788474, Length=311, Percent_Identity=31.1897106109325, Blast_Score=155, Evalue=3e-39,
Organism=Escherichia coli, GI1789202, Length=296, Percent_Identity=33.1081081081081, Blast_Score=155, Evalue=5e-39,
Organism=Escherichia coli, GI1786540, Length=321, Percent_Identity=30.8411214953271, Blast_Score=134, Evalue=6e-33,
Organism=Escherichia coli, GI1787580, Length=312, Percent_Identity=27.8846153846154, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1790715, Length=316, Percent_Identity=26.8987341772152, Blast_Score=107, Evalue=8e-25,
Organism=Escherichia coli, GI48994940, Length=311, Percent_Identity=25.7234726688103, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1789456, Length=302, Percent_Identity=28.8079470198675, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1787906, Length=333, Percent_Identity=21.6216216216216, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1786268, Length=297, Percent_Identity=21.5488215488215, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI1790192, Length=250, Percent_Identity=27.2, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790689, Length=326, Percent_Identity=20.8588957055215, Blast_Score=69, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): EXUR_BACSU (Q9JMQ1)

Other databases:

- EMBL:   AF015825
- EMBL:   AL009126
- PIR:   B69853
- RefSeq:   NP_389119.1
- HSSP:   P46828
- ProteinModelPortal:   Q9JMQ1
- SMR:   Q9JMQ1
- EnsemblBacteria:   EBBACT00000001371
- GeneID:   939834
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU12370
- NMPDR:   fig|224308.1.peg.1238
- GenoList:   BSU12370
- GeneTree:   EBGT00070000031749
- HOGENOM:   HBG753640
- OMA:   HIREKNI
- PhylomeDB:   Q9JMQ1
- ProtClustDB:   CLSK882528
- BioCyc:   BSUB:BSU12370-MONOMER
- GO:   GO:0005622
- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761
- PRINTS:   PR00036
- SMART:   SM00354

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1; SSF47413 Lambda_like_DNA

EC number: NA

Molecular weight: Translated: 37381; Mature: 37381

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS00356 HTH_LACI_1; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTIKDIAKLANVSHTTVSRALNNSPYIKEHTKKKILELAEQLNYTPNVNAKSLAMQKSH
CCCHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCC
TIGLFFTSITNGTSHSFFADTIKGVNQAISEDYNLYVRGIDDLKNYDSVTPMRYDGIILM
EEEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCEEEEEECHHHHCCCCCCCEEECCEEEE
SQSDIDNSFIYHIREKNIPLVVLNRDIDDRTITNILSNDKEGSQEAVEYFIQSGHQDIAI
ECCCCCCCEEEEEECCCCCEEEEECCCCHHHHHHHHCCCCCCHHHHHHHHHHCCCCCEEE
IEGIEGFKSSQQRKEGYLSALIQHHIPIKHEYSVKGQYDMESGFQAMERLLALPNPPTAV
ECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEE
FCSNDDMAIGAMNAIFAKGLRVPDDISVIGFDDIGFSQYITPRLSTVKRPVEKISVLGAQ
EECCCCCCHHHHHHHHHCCCCCCCCCEEEEECCCCCHHHCCHHHHHHHHHHHHHHHHHHH
KLLSLISEPETKAEKILENTEFMVRDSVRRLTT
HHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHCC
>Mature Secondary Structure
MVTIKDIAKLANVSHTTVSRALNNSPYIKEHTKKKILELAEQLNYTPNVNAKSLAMQKSH
CCCHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCC
TIGLFFTSITNGTSHSFFADTIKGVNQAISEDYNLYVRGIDDLKNYDSVTPMRYDGIILM
EEEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCEEEEEECHHHHCCCCCCCEEECCEEEE
SQSDIDNSFIYHIREKNIPLVVLNRDIDDRTITNILSNDKEGSQEAVEYFIQSGHQDIAI
ECCCCCCCEEEEEECCCCCEEEEECCCCHHHHHHHHCCCCCCHHHHHHHHHHCCCCCEEE
IEGIEGFKSSQQRKEGYLSALIQHHIPIKHEYSVKGQYDMESGFQAMERLLALPNPPTAV
ECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEE
FCSNDDMAIGAMNAIFAKGLRVPDDISVIGFDDIGFSQYITPRLSTVKRPVEKISVLGAQ
EECCCCCCHHHHHHHHHCCCCCCCCCEEEEECCCCCHHHCCHHHHHHHHHHHHHHHHHHH
KLLSLISEPETKAEKILENTEFMVRDSVRRLTT
HHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579062; 9384377