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The map label for this gene is exuT

Identifier: 16078301

GI number: 16078301

Start: 1307446

End: 1308714

Strand: Direct

Name: exuT

Synonym: BSU12360

Alternate gene names: 16078301

Gene position: 1307446-1308714 (Clockwise)

Preceding gene: 16078300

Following gene: 16078302

Centisome position: 31.01

GC content: 49.01

Gene sequence:

>1269_bases
ATGTTTTCAAAAGATAAGCTTCCCGTTATCCTTTTTTTGTTCCTGGCAGGGGTGATTAATTACCTGGATCGCTCGGCGCT
TTCCATTGCAGCTCCTTTTATTCAGGATGATCTCACATTGTCTGCCACACAAATGGGCTTGATTTTCAGCAGTTTTTCGA
TAGGTTATGCCATTTTTAATTTTCTTGGGGGCGTGGCATCCGACCGCTATGGGGCAAAGCTGACCTTGTTTGTCGCGATG
GTTGTTTGGTCGCTGTTTAGCGGAGCAGTCGCCCTCGCTTTTGGCTTTGTCAGCCTGCTGATTATACGCATTCTCTTCGG
AATGGGAGAAGGCCCGCTTTCGGCGACCATCAACAAGATGGTGAACAACTGGTTCCCGCCGACCCAGCGGGCGTCCGTTA
TCGGTGTAACCAACAGCGGCACGCCCCTCGGGGGAGCCATTTCCGGCCCGATAGTCGGCATGATCGCAGTGGCGTTCAGC
TGGAAGGTATCCTTCGTTCTCATTATGATTATTGGATTGATATGGGCAGTGCTCTGGTTCAAGTTTGTCAAAGAAAAGCC
GCAAGAGACGATCAAGGAAGCACCGGCAATAAAAGCAGAAACGTCTCCCGGAGAAAAAATTCCGCTCACCTTTTACCTGA
AGCAAAAAACAGTCCTGTTCACGGCGTTCGCTTTTTTCGCTTACAACTACATCCTCTTCTTCTTTTTGACATGGTTTCCG
AGCTATCTTGTCGACGAGCGGGGATTAAGTGTTGAATCGATGAGTGTCATCACGGTCATACCGTGGATTTTAGGATTTAT
CGGGCTGGCTGCGGGGGGATTTGTTTCTGACTATGTGTACAAAAAAACGGCCCGAAAAGGTGTGCTGTTCTCGCGCAAGG
TTGTGCTTGTCACGTGTTTGTTTTCATCAGCTGTCCTGATTGGTTTTGCCGGGCTTGTGGCAACGACTGCGGGGGCTGTC
ACTCTTGTCGCTCTGTCAGTGTTCTTTCTTTATTTGACCGGTGCTATCTATTGGGCTGTCATTCAAGATGTGGTTGATCA
AAACAATGTCGGTTCTGTTGGCGGCTTCATGCATTTCCTCGCCAACACGGCAGGAATTATCGGCCCGGCTTTAACCGGAT
TTATTGTTGACCAAACAGGCACGTTTTCTGGAGCATTTTTGCTTGCCGGTGGGCTGGCTGTCTTCGCTTCACTTGCTGTG
ATTCGTTTTGTCCGTCCAATCATTGGTAAGCCAGCGGGAACAGAAGCTGAGAATCCTGTGTCTTATTAA

Upstream 100 bases:

>100_bases
CTGGGATCACCGTTCCTGTCGATGGAGGATTTATGGCTTATTCAGGTGTGTAACGAAAGCGGTGCAACAGAAACTGAACC
AACATAGGGGTGAGGTTGAG

Downstream 100 bases:

>100_bases
TCTGGAAATATAGTGGGAGAGGCGGTATGTTTGATGATACAATATACAGTAAATAATCGCAGCCGGTATGATAAGGAAGG
GAATTAGATGGTAACCATAA

Product: hexuronate transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 422; Mature: 422

Protein sequence:

>422_residues
MFSKDKLPVILFLFLAGVINYLDRSALSIAAPFIQDDLTLSATQMGLIFSSFSIGYAIFNFLGGVASDRYGAKLTLFVAM
VVWSLFSGAVALAFGFVSLLIIRILFGMGEGPLSATINKMVNNWFPPTQRASVIGVTNSGTPLGGAISGPIVGMIAVAFS
WKVSFVLIMIIGLIWAVLWFKFVKEKPQETIKEAPAIKAETSPGEKIPLTFYLKQKTVLFTAFAFFAYNYILFFFLTWFP
SYLVDERGLSVESMSVITVIPWILGFIGLAAGGFVSDYVYKKTARKGVLFSRKVVLVTCLFSSAVLIGFAGLVATTAGAV
TLVALSVFFLYLTGAIYWAVIQDVVDQNNVGSVGGFMHFLANTAGIIGPALTGFIVDQTGTFSGAFLLAGGLAVFASLAV
IRFVRPIIGKPAGTEAENPVSY

Sequences:

>Translated_422_residues
MFSKDKLPVILFLFLAGVINYLDRSALSIAAPFIQDDLTLSATQMGLIFSSFSIGYAIFNFLGGVASDRYGAKLTLFVAM
VVWSLFSGAVALAFGFVSLLIIRILFGMGEGPLSATINKMVNNWFPPTQRASVIGVTNSGTPLGGAISGPIVGMIAVAFS
WKVSFVLIMIIGLIWAVLWFKFVKEKPQETIKEAPAIKAETSPGEKIPLTFYLKQKTVLFTAFAFFAYNYILFFFLTWFP
SYLVDERGLSVESMSVITVIPWILGFIGLAAGGFVSDYVYKKTARKGVLFSRKVVLVTCLFSSAVLIGFAGLVATTAGAV
TLVALSVFFLYLTGAIYWAVIQDVVDQNNVGSVGGFMHFLANTAGIIGPALTGFIVDQTGTFSGAFLLAGGLAVFASLAV
IRFVRPIIGKPAGTEAENPVSY
>Mature_422_residues
MFSKDKLPVILFLFLAGVINYLDRSALSIAAPFIQDDLTLSATQMGLIFSSFSIGYAIFNFLGGVASDRYGAKLTLFVAM
VVWSLFSGAVALAFGFVSLLIIRILFGMGEGPLSATINKMVNNWFPPTQRASVIGVTNSGTPLGGAISGPIVGMIAVAFS
WKVSFVLIMIIGLIWAVLWFKFVKEKPQETIKEAPAIKAETSPGEKIPLTFYLKQKTVLFTAFAFFAYNYILFFFLTWFP
SYLVDERGLSVESMSVITVIPWILGFIGLAAGGFVSDYVYKKTARKGVLFSRKVVLVTCLFSSAVLIGFAGLVATTAGAV
TLVALSVFFLYLTGAIYWAVIQDVVDQNNVGSVGGFMHFLANTAGIIGPALTGFIVDQTGTFSGAFLLAGGLAVFASLAV
IRFVRPIIGKPAGTEAENPVSY

Specific function: Aldohexuronate transport system

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family

Homologues:

Organism=Homo sapiens, GI6912666, Length=377, Percent_Identity=23.342175066313, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI154350196, Length=396, Percent_Identity=20.4545454545455, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI4885441, Length=363, Percent_Identity=19.5592286501377, Blast_Score=79, Evalue=9e-15,
Organism=Homo sapiens, GI5031955, Length=254, Percent_Identity=23.2283464566929, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI148743791, Length=353, Percent_Identity=21.2464589235127, Blast_Score=76, Evalue=6e-14,
Organism=Homo sapiens, GI21322234, Length=325, Percent_Identity=23.3846153846154, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI9966811, Length=331, Percent_Identity=21.7522658610272, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI9945322, Length=255, Percent_Identity=23.1372549019608, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI2367379, Length=409, Percent_Identity=30.8068459657702, Blast_Score=211, Evalue=7e-56,
Organism=Escherichia coli, GI1789515, Length=412, Percent_Identity=30.3398058252427, Blast_Score=180, Evalue=2e-46,
Organism=Escherichia coli, GI1789152, Length=423, Percent_Identity=30.0236406619385, Blast_Score=180, Evalue=2e-46,
Organism=Escherichia coli, GI87082320, Length=421, Percent_Identity=29.6912114014252, Blast_Score=172, Evalue=4e-44,
Organism=Escherichia coli, GI2367193, Length=426, Percent_Identity=24.8826291079812, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI87082071, Length=418, Percent_Identity=22.2488038277512, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788573, Length=454, Percent_Identity=22.0264317180617, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87081723, Length=235, Percent_Identity=26.8085106382979, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI87082310, Length=293, Percent_Identity=19.7952218430034, Blast_Score=66, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI115533556, Length=348, Percent_Identity=25.5747126436782, Blast_Score=96, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI115533554, Length=348, Percent_Identity=25.5747126436782, Blast_Score=95, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI17552542, Length=371, Percent_Identity=25.0673854447439, Blast_Score=93, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI32565914, Length=230, Percent_Identity=25.6521739130435, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI32565916, Length=230, Percent_Identity=25.6521739130435, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17569727, Length=259, Percent_Identity=24.3243243243243, Blast_Score=72, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17535049, Length=258, Percent_Identity=23.6434108527132, Blast_Score=72, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17560030, Length=256, Percent_Identity=25.78125, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71991448, Length=391, Percent_Identity=23.5294117647059, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71991453, Length=391, Percent_Identity=23.5294117647059, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI193205400, Length=215, Percent_Identity=23.7209302325581, Blast_Score=68, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17540458, Length=250, Percent_Identity=22.4, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24648416, Length=366, Percent_Identity=25.6830601092896, Blast_Score=92, Evalue=1e-18,
Organism=Drosophila melanogaster, GI21356189, Length=366, Percent_Identity=25.6830601092896, Blast_Score=92, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24584153, Length=350, Percent_Identity=23.1428571428571, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24639764, Length=435, Percent_Identity=23.448275862069, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI19920686, Length=391, Percent_Identity=23.7851662404092, Blast_Score=89, Evalue=7e-18,
Organism=Drosophila melanogaster, GI19922400, Length=367, Percent_Identity=26.158038147139, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24654215, Length=367, Percent_Identity=26.158038147139, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24583789, Length=388, Percent_Identity=26.0309278350515, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24655271, Length=400, Percent_Identity=24.75, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI20130135, Length=400, Percent_Identity=24.75, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24641682, Length=403, Percent_Identity=22.5806451612903, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24655255, Length=381, Percent_Identity=21.259842519685, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI45550460, Length=381, Percent_Identity=21.259842519685, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI45552797, Length=370, Percent_Identity=26.2162162162162, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24658689, Length=404, Percent_Identity=26.2376237623762, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24658666, Length=383, Percent_Identity=25.5874673629243, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI28573708, Length=391, Percent_Identity=23.7851662404092, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI28573707, Length=391, Percent_Identity=23.7851662404092, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI45550495, Length=371, Percent_Identity=23.989218328841, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24658658, Length=408, Percent_Identity=21.5686274509804, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI28573299, Length=270, Percent_Identity=24.0740740740741, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI45550364, Length=446, Percent_Identity=23.9910313901345, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24580790, Length=363, Percent_Identity=22.5895316804408, Blast_Score=66, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): EXUT_BACSU (O34456)

Other databases:

- EMBL:   AF015825
- EMBL:   AL009126
- PIR:   A69853
- RefSeq:   NP_389118.1
- ProteinModelPortal:   O34456
- EnsemblBacteria:   EBBACT00000003748
- GeneID:   939405
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU12360
- NMPDR:   fig|224308.1.peg.1237
- GenoList:   BSU12360
- GeneTree:   EBGT00050000000112
- HOGENOM:   HBG338043
- OMA:   HFLANTA
- PhylomeDB:   O34456
- ProtClustDB:   CLSK887108
- BioCyc:   BSUB:BSU12360-MONOMER
- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- TIGRFAMs:   TIGR00893

Pfam domain/function: PF07690 MFS_1; SSF103473 MFS_gen_substrate_transporter

EC number: NA

Molecular weight: Translated: 45314; Mature: 45314

Theoretical pI: Translated: 9.74; Mature: 9.74

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xeaade84)-; HASH(0xe66d4d0)-; HASH(0xe62f97c)-; HASH(0xe2e4c6c)-; HASH(0xd650fbc)-; HASH(0xe5e96f8)-; HASH(0xce5b758)-; HASH(0xe747a38)-; HASH(0xdfa42e8)-; HASH(0xe662924)-; HASH(0xe6ca498)-;

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CH
>Mature Secondary Structure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CH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579062; 9384377