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The map label for this gene is argB

Identifier: 16078186

GI number: 16078186

Start: 1197326

End: 1198102

Strand: Direct

Name: argB

Synonym: BSU11210

Alternate gene names: 16078186

Gene position: 1197326-1198102 (Clockwise)

Preceding gene: 255767252

Following gene: 255767253

Centisome position: 28.4

GC content: 48.13

Gene sequence:

>777_bases
ATGAAGAAAACAATCGTTTTTAAATGCGGGGGAAGCGTCATCCGTGAGCTGTCGGAGGAATTTTATCAAAATCTGAAAGA
GCTGAGGGCGTCAGGCTGGAAGCTGGCAATCGTACATGGCGGGGGACCGGAAATCACAAATATGCTGAAACGGTTAAATA
TCAAGACAGAGTTTTCGGGCGGACAGAGGAAAACAACGAAGCCGGTGCTGGAAGTGGCGGAAATGGTTTTATCCGGTTCT
GTCAATAAATTTTTCGTTGCTGAGCTTGCCAAACACGGACTGCGAGCCGCGGGCATTTCTGGTAAGGATGGCGGTCTTTT
GGAGGCTGATTATCTAGATCCGGAAACATACGGAGAAGTGGGAGAAATCAAAAAAGTCGATGCGTCCATGGTGAACGCGC
TGATGGAAAATGGCATCATCCCCGTTATTGCGCCGCTGTCTATGACAAGCGACTGCAAAACGCTGAATGTAAATGCTGAT
CTGGCTGCTTCAGCAGTCGCCGGAGCGCTTGAAGCCGATAAGCTGATGTTCGTCACGGATGTCGATGGAATCATGAAGGA
AAAGCAGCGTCTGGACGTCCTGACCCCTAAGGAGATTCAGATGCTGATCAAGCAGGAAGTGATCACAGGAGGGATGATCC
CGAAGGTCAATTCAGCCTTGTCAGCTTTATCAGATCAGGTGTCTGAAGTCATGATCGTAAACGGTAAAGGATCATTCTTC
GCAGAACAAACCTTTCAAGGGACAAAAATTGTCAAAGCAAAGGAGGCTGTTTCATGA

Upstream 100 bases:

>100_bases
TGGCTGAAGGGGACGGAAACGGGAGAGCGTGGGGCTGTGACCTGACCTATGACTATATCAAAATTAACGCGAGCTATCGC
ACGTAATAAAGGGGAGCGAA

Downstream 100 bases:

>100_bases
GCAGCTTGTTTCAAACCTACGGCCGTTGGGATATTGACATCAAAAAAGCAAAGGGAACGTACGTTGAGGATCAAAACGGC
AAAACGTACCTTGATTTCAT

Product: acetylglutamate kinase

Products: NA

Alternate protein names: N-acetyl-L-glutamate 5-phosphotransferase; NAG kinase; AGK

Number of amino acids: Translated: 258; Mature: 258

Protein sequence:

>258_residues
MKKTIVFKCGGSVIRELSEEFYQNLKELRASGWKLAIVHGGGPEITNMLKRLNIKTEFSGGQRKTTKPVLEVAEMVLSGS
VNKFFVAELAKHGLRAAGISGKDGGLLEADYLDPETYGEVGEIKKVDASMVNALMENGIIPVIAPLSMTSDCKTLNVNAD
LAASAVAGALEADKLMFVTDVDGIMKEKQRLDVLTPKEIQMLIKQEVITGGMIPKVNSALSALSDQVSEVMIVNGKGSFF
AEQTFQGTKIVKAKEAVS

Sequences:

>Translated_258_residues
MKKTIVFKCGGSVIRELSEEFYQNLKELRASGWKLAIVHGGGPEITNMLKRLNIKTEFSGGQRKTTKPVLEVAEMVLSGS
VNKFFVAELAKHGLRAAGISGKDGGLLEADYLDPETYGEVGEIKKVDASMVNALMENGIIPVIAPLSMTSDCKTLNVNAD
LAASAVAGALEADKLMFVTDVDGIMKEKQRLDVLTPKEIQMLIKQEVITGGMIPKVNSALSALSDQVSEVMIVNGKGSFF
AEQTFQGTKIVKAKEAVS
>Mature_258_residues
MKKTIVFKCGGSVIRELSEEFYQNLKELRASGWKLAIVHGGGPEITNMLKRLNIKTEFSGGQRKTTKPVLEVAEMVLSGS
VNKFFVAELAKHGLRAAGISGKDGGLLEADYLDPETYGEVGEIKKVDASMVNALMENGIIPVIAPLSMTSDCKTLNVNAD
LAASAVAGALEADKLMFVTDVDGIMKEKQRLDVLTPKEIQMLIKQEVITGGMIPKVNSALSALSDQVSEVMIVNGKGSFF
AEQTFQGTKIVKAKEAVS

Specific function: Arginine biosynthesis; second step. [C]

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetylglutamate kinase family

Homologues:

Organism=Escherichia coli, GI145693208, Length=226, Percent_Identity=36.283185840708, Blast_Score=112, Evalue=3e-26,
Organism=Saccharomyces cerevisiae, GI6320913, Length=180, Percent_Identity=31.1111111111111, Blast_Score=83, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGB_BACAM (P68728)

Other databases:

- EMBL:   AF001832
- ProteinModelPortal:   P68728
- SMR:   P68728
- BRENDA:   2.7.2.8
- GO:   GO:0005737
- HAMAP:   MF_00082_B
- InterPro:   IPR004662
- InterPro:   IPR001048
- InterPro:   IPR001057
- Gene3D:   G3DSA:3.40.1160.10
- PIRSF:   PIRSF000728
- PRINTS:   PR00474
- TIGRFAMs:   TIGR00761

Pfam domain/function: PF00696 AA_kinase; SSF53633 Aa_kinase

EC number: =2.7.2.8

Molecular weight: Translated: 27725; Mature: 27725

Theoretical pI: Translated: 6.56; Mature: 6.56

Prosite motif: NA

Important sites: BINDING 63-63 BINDING 156-156

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKTIVFKCGGSVIRELSEEFYQNLKELRASGWKLAIVHGGGPEITNMLKRLNIKTEFSG
CCCEEEEECCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHCCCCEECCC
GQRKTTKPVLEVAEMVLSGSVNKFFVAELAKHGLRAAGISGKDGGLLEADYLDPETYGEV
CCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCEECCCCCCCCCEEEECCCCCHHCCCH
GEIKKVDASMVNALMENGIIPVIAPLSMTSDCKTLNVNADLAASAVAGALEADKLMFVTD
HHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCEEECCCCHHHHHHHHHHCCCCEEEEEC
VDGIMKEKQRLDVLTPKEIQMLIKQEVITGGMIPKVNSALSALSDQVSEVMIVNGKGSFF
CHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHEEEEECCCCCEE
AEQTFQGTKIVKAKEAVS
HHHHCCCCEEEHHHHHCC
>Mature Secondary Structure
MKKTIVFKCGGSVIRELSEEFYQNLKELRASGWKLAIVHGGGPEITNMLKRLNIKTEFSG
CCCEEEEECCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHCCCCEECCC
GQRKTTKPVLEVAEMVLSGSVNKFFVAELAKHGLRAAGISGKDGGLLEADYLDPETYGEV
CCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCEECCCCCCCCCEEEECCCCCHHCCCH
GEIKKVDASMVNALMENGIIPVIAPLSMTSDCKTLNVNADLAASAVAGALEADKLMFVTD
HHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCEEECCCCHHHHHHHHHHCCCCEEEEEC
VDGIMKEKQRLDVLTPKEIQMLIKQEVITGGMIPKVNSALSALSDQVSEVMIVNGKGSFF
CHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHEEEEECCCCCEE
AEQTFQGTKIVKAKEAVS
HHHHCCCCEEEHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA