Click here to switch to the map view.

The map label for this gene is yisZ

Identifier: 16078155

GI number: 16078155

Start: 1169877

End: 1170476

Strand: Reverse

Name: yisZ

Synonym: BSU10910

Alternate gene names: 16078155

Gene position: 1170476-1169877 (Counterclockwise)

Preceding gene: 50812214

Following gene: 16078153

Centisome position: 27.77

GC content: 46.83

Gene sequence:

>600_bases
ATGACACACAATCCGAACATCATTTGGCATCCCGCTGCCATCTCAAAGTCTGACAGACAGTCCTTAAACGGACACAAAAG
CTGCGTCCTTTGGTTTACAGGTTTGTCCGGCTCCGGAAAATCGGTGCTGGCCAATGCTGTCGATGAAAAGCTTTACCGCA
AGGGCATTCAGAGCTACGTGCTTGACGGTGATAATATCCGCCACGGCTTAAACAAAGATCTTGGATTTCAGACTGGTGAC
AGGATTGAAAACATCCGCCGGATCGGAGAAGTGGCGAAGCTGTTTGTCGACAGCGGGCAAATGATTTTAACGGCTTTTAT
TTCTCCATTCAGAGAGGATCGGGACATGGTTAGAGCGCTCTTTCCTAAAGGTGAGTTCTTCGAAATTTATGTGAAGTGCC
CGCTGCATGTTTGTGAACAGCGCGATCCAAAAGGGCTTTATAAAAAAGCGCGAAACGGAGAGATCAAACATTTCACCGGG
ATCGATTCTCCGTATGAAGCGCCGCTTTCACCCGATTTCATCATTGAGTCTGACCAGACCTCTATTTCCGATGGAGCTGA
TCTCATCATTAACGCACTGCAAAACAGAGGAATTATATAA

Upstream 100 bases:

>100_bases
AGCCGCCTAAAGAATTCAGCCGGCCTGAGGTCGCAGCCGTGCTGATCAAGGGACTTCACCAACAGCCTGTTGCCATCAAG
CAAAACAGCGGGGAATTGCA

Downstream 100 bases:

>100_bases
AAAACCCGATCAATGTCGGGTTTTTTCTTATGAGTTGGAGAACTGCGCAATCAAACTGTTGATCTTCTCTTTTTCCTCAT
AAAATGCTCCGTGCCCGCTG

Product: adenylylsulfate kinase

Products: NA

Alternate protein names: APS kinase; ATP adenosine-5'-phosphosulfate 3'-phosphotransferase; Adenosine-5'-phosphosulfate kinase

Number of amino acids: Translated: 199; Mature: 198

Protein sequence:

>199_residues
MTHNPNIIWHPAAISKSDRQSLNGHKSCVLWFTGLSGSGKSVLANAVDEKLYRKGIQSYVLDGDNIRHGLNKDLGFQTGD
RIENIRRIGEVAKLFVDSGQMILTAFISPFREDRDMVRALFPKGEFFEIYVKCPLHVCEQRDPKGLYKKARNGEIKHFTG
IDSPYEAPLSPDFIIESDQTSISDGADLIINALQNRGII

Sequences:

>Translated_199_residues
MTHNPNIIWHPAAISKSDRQSLNGHKSCVLWFTGLSGSGKSVLANAVDEKLYRKGIQSYVLDGDNIRHGLNKDLGFQTGD
RIENIRRIGEVAKLFVDSGQMILTAFISPFREDRDMVRALFPKGEFFEIYVKCPLHVCEQRDPKGLYKKARNGEIKHFTG
IDSPYEAPLSPDFIIESDQTSISDGADLIINALQNRGII
>Mature_198_residues
THNPNIIWHPAAISKSDRQSLNGHKSCVLWFTGLSGSGKSVLANAVDEKLYRKGIQSYVLDGDNIRHGLNKDLGFQTGDR
IENIRRIGEVAKLFVDSGQMILTAFISPFREDRDMVRALFPKGEFFEIYVKCPLHVCEQRDPKGLYKKARNGEIKHFTGI
DSPYEAPLSPDFIIESDQTSISDGADLIINALQNRGII

Specific function: Catalyzes the synthesis of activated sulfate

COG id: COG0529

COG function: function code P; Adenylylsulfate kinase and related kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the APS kinase family

Homologues:

Organism=Homo sapiens, GI46094058, Length=205, Percent_Identity=47.8048780487805, Blast_Score=204, Evalue=4e-53,
Organism=Homo sapiens, GI34447231, Length=200, Percent_Identity=47, Blast_Score=199, Evalue=1e-51,
Organism=Homo sapiens, GI62912492, Length=200, Percent_Identity=47, Blast_Score=199, Evalue=1e-51,
Organism=Escherichia coli, GI1789107, Length=197, Percent_Identity=51.2690355329949, Blast_Score=221, Evalue=2e-59,
Organism=Caenorhabditis elegans, GI17542422, Length=200, Percent_Identity=47, Blast_Score=187, Evalue=2e-48,
Organism=Saccharomyces cerevisiae, GI6322852, Length=196, Percent_Identity=52.5510204081633, Blast_Score=210, Evalue=1e-55,
Organism=Drosophila melanogaster, GI24667032, Length=178, Percent_Identity=49.438202247191, Blast_Score=185, Evalue=1e-47,
Organism=Drosophila melanogaster, GI24667028, Length=178, Percent_Identity=49.438202247191, Blast_Score=185, Evalue=1e-47,
Organism=Drosophila melanogaster, GI24667036, Length=178, Percent_Identity=49.438202247191, Blast_Score=185, Evalue=1e-47,
Organism=Drosophila melanogaster, GI24667040, Length=178, Percent_Identity=49.438202247191, Blast_Score=185, Evalue=2e-47,
Organism=Drosophila melanogaster, GI116007838, Length=178, Percent_Identity=49.438202247191, Blast_Score=185, Evalue=2e-47,
Organism=Drosophila melanogaster, GI24667044, Length=178, Percent_Identity=49.438202247191, Blast_Score=185, Evalue=2e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CYSC2_BACSU (O06735)

Other databases:

- EMBL:   Y09476
- EMBL:   AL009126
- PIR:   A69839
- RefSeq:   NP_388972.1
- ProteinModelPortal:   O06735
- SMR:   O06735
- EnsemblBacteria:   EBBACT00000003195
- GeneID:   936359
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU10910
- NMPDR:   fig|224308.1.peg.1091
- GenoList:   BSU10910
- GeneTree:   EBGT00050000001911
- HOGENOM:   HBG309946
- OMA:   SDRIENI
- PhylomeDB:   O06735
- ProtClustDB:   CLSK2752366
- BioCyc:   BSUB:BSU10910-MONOMER
- BRENDA:   2.7.1.25
- HAMAP:   MF_00065
- InterPro:   IPR002891
- TIGRFAMs:   TIGR00455

Pfam domain/function: PF01583 APS_kinase

EC number: =2.7.1.25

Molecular weight: Translated: 22305; Mature: 22173

Theoretical pI: Translated: 7.60; Mature: 7.60

Prosite motif: NA

Important sites: ACT_SITE 108-108

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHNPNIIWHPAAISKSDRQSLNGHKSCVLWFTGLSGSGKSVLANAVDEKLYRKGIQSYV
CCCCCCEEECCCCCCCHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHH
LDGDNIRHGLNKDLGFQTGDRIENIRRIGEVAKLFVDSGQMILTAFISPFREDRDMVRAL
CCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
FPKGEFFEIYVKCPLHVCEQRDPKGLYKKARNGEIKHFTGIDSPYEAPLSPDFIIESDQT
CCCCCEEEEEEECCHHHHCCCCCHHHHHHHCCCCCEEECCCCCCCCCCCCCCEEEECCCC
SISDGADLIINALQNRGII
CCCCCHHHHHHHHHHCCCC
>Mature Secondary Structure 
THNPNIIWHPAAISKSDRQSLNGHKSCVLWFTGLSGSGKSVLANAVDEKLYRKGIQSYV
CCCCCEEECCCCCCCHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHH
LDGDNIRHGLNKDLGFQTGDRIENIRRIGEVAKLFVDSGQMILTAFISPFREDRDMVRAL
CCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
FPKGEFFEIYVKCPLHVCEQRDPKGLYKKARNGEIKHFTGIDSPYEAPLSPDFIIESDQT
CCCCCEEEEEEECCHHHHCCCCCHHHHHHHCCCCCEEECCCCCCCCCCCCCCEEEECCCC
SISDGADLIINALQNRGII
CCCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9353932; 9384377