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The map label for this gene is yhdT

Identifier: 16078024

GI number: 16078024

Start: 1035554

End: 1036939

Strand: Direct

Name: yhdT

Synonym: BSU09590

Alternate gene names: 16078024

Gene position: 1035554-1036939 (Clockwise)

Preceding gene: 16078022

Following gene: 16078028

Centisome position: 24.56

GC content: 46.75

Gene sequence:

>1386_bases
ATGGACGATATTGACAGTCTGATTTTAATTGGCGTGCTCATTGCTTTAACCGCGTTTTTCGTTGCAAGCGAGTTTGCGAT
TGTTAGAGTGAGGAGATCCAGAATAGATCAGCTTATCACAGAAGGAAACAAACGGGCGATACTCGCAAGGCGTGTCATTA
CAGATTTGGATGAATATTTATCCGCATCCCAGCTAGGCATTACATTGACATCAATCGGGCTTGGCGTACTGGGTGAGCCG
GCCTTTGAACGGCTGCTGCATCCACTGTTTGAACCGCTCGGCTTGCCGGACTCGGTTTCACATGCAGTCTCTTTTGCAGT
CGCGTACGGCTTGATCACGTTCCTGCACGTTGTTGTAGGTGAACTGGCCCCGAAAACGGTCGCGATTCAAAAGGCAGAAC
AGCTGACTTTACTGATAGCGGGCCCTTTGCGTTTATTCTATTTGCTCCTGTTTCCGTTTATTTGGATCCTCAATGGATCG
GCGCGGCTTTTATGCGGGATGTTCGGTTTGAAGCCTGCGTCAGAACATGATGGTTCCCATTCTGAGGAAGAACTCAGGAT
GCTGTTATCTGAGAGTTTAAAAAACGGAGAGATTAATCCGTCTGAATATAAATATGTGAATAAGATTTTTGAATTTGATA
ATCGGATCGCCAAAGAAATTATGATACCGCGGAAGGAAATGGCTGCTGTGTCAACTGAGATGACGATGGCCGAGATGCTT
GAAGTCATGCTGAAGGAAAAATACACGCGCTGGCCAGTCACAGATGGAGACAAAGACAGTGTGCTCGGTTTGGTCAATAC
GAAGCATTTGTTTTCTGATTTGCTGTTTATGACAGAAGAAGAACGAATGAAGATGACGATCCATCCGTATGTGAGGCCGG
TCATCGAAGTGATTGAAACGATCCCGGTTCATGACTTGCTGATTAAAATGCAGCGCGAGCGCATTCATATGGCTATATTG
TCGGATGAATACGGAGGAACCTCGGGACTTGTGACGACAGAGGATATTCTTGAGGAAATTGTCGGAGAGATCCGAGATGA
ATTTGATGAAGATGAACAGCCGCTGATCCAAAAGCTTGGCGACGGCCATTATGTGATGGATGGAAAGGTTCGGATCGATC
AGGTGAACAGCCTTCTTGGCGCATCGATTCAAGAAGACGTCGATACGATCGGCGGGCTGATATTAAAAGAAAACATCGAT
ATTGAGGCTGGTGAATCCATTCGCATCGGTTCATATACGATAAAGGTGCTGAAGATGGACGGCCGATTAATCAAGCAAAT
CGATATAAAAGAAGAAGCCGGCAACACAACCGGGATTACGGCGCACCACAAGCTGCCGCTGCCCGAGCCTGTGATGCTGA
ACAGTGCAACCTTGAGCGAGAAATAA

Upstream 100 bases:

>100_bases
CCCTCTGCTTAGGCAACAATACACCGCGTACCTCAATGTTAAGGAAAAATGATTATATCAGGAGGTGACTCCTTATCCTT
TGTTGAGAGGATAGGGTTAA

Downstream 100 bases:

>100_bases
GCTCAAGGTTTTTTTATATTGTGATTGTCCAGCCGCACCAAAATGCAAAAAGCGACCCGCAAAGTGTCAGGACGATGTAC
AAGATGCTTTCTTTTACACG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 461; Mature: 461

Protein sequence:

>461_residues
MDDIDSLILIGVLIALTAFFVASEFAIVRVRRSRIDQLITEGNKRAILARRVITDLDEYLSASQLGITLTSIGLGVLGEP
AFERLLHPLFEPLGLPDSVSHAVSFAVAYGLITFLHVVVGELAPKTVAIQKAEQLTLLIAGPLRLFYLLLFPFIWILNGS
ARLLCGMFGLKPASEHDGSHSEEELRMLLSESLKNGEINPSEYKYVNKIFEFDNRIAKEIMIPRKEMAAVSTEMTMAEML
EVMLKEKYTRWPVTDGDKDSVLGLVNTKHLFSDLLFMTEEERMKMTIHPYVRPVIEVIETIPVHDLLIKMQRERIHMAIL
SDEYGGTSGLVTTEDILEEIVGEIRDEFDEDEQPLIQKLGDGHYVMDGKVRIDQVNSLLGASIQEDVDTIGGLILKENID
IEAGESIRIGSYTIKVLKMDGRLIKQIDIKEEAGNTTGITAHHKLPLPEPVMLNSATLSEK

Sequences:

>Translated_461_residues
MDDIDSLILIGVLIALTAFFVASEFAIVRVRRSRIDQLITEGNKRAILARRVITDLDEYLSASQLGITLTSIGLGVLGEP
AFERLLHPLFEPLGLPDSVSHAVSFAVAYGLITFLHVVVGELAPKTVAIQKAEQLTLLIAGPLRLFYLLLFPFIWILNGS
ARLLCGMFGLKPASEHDGSHSEEELRMLLSESLKNGEINPSEYKYVNKIFEFDNRIAKEIMIPRKEMAAVSTEMTMAEML
EVMLKEKYTRWPVTDGDKDSVLGLVNTKHLFSDLLFMTEEERMKMTIHPYVRPVIEVIETIPVHDLLIKMQRERIHMAIL
SDEYGGTSGLVTTEDILEEIVGEIRDEFDEDEQPLIQKLGDGHYVMDGKVRIDQVNSLLGASIQEDVDTIGGLILKENID
IEAGESIRIGSYTIKVLKMDGRLIKQIDIKEEAGNTTGITAHHKLPLPEPVMLNSATLSEK
>Mature_461_residues
MDDIDSLILIGVLIALTAFFVASEFAIVRVRRSRIDQLITEGNKRAILARRVITDLDEYLSASQLGITLTSIGLGVLGEP
AFERLLHPLFEPLGLPDSVSHAVSFAVAYGLITFLHVVVGELAPKTVAIQKAEQLTLLIAGPLRLFYLLLFPFIWILNGS
ARLLCGMFGLKPASEHDGSHSEEELRMLLSESLKNGEINPSEYKYVNKIFEFDNRIAKEIMIPRKEMAAVSTEMTMAEML
EVMLKEKYTRWPVTDGDKDSVLGLVNTKHLFSDLLFMTEEERMKMTIHPYVRPVIEVIETIPVHDLLIKMQRERIHMAIL
SDEYGGTSGLVTTEDILEEIVGEIRDEFDEDEQPLIQKLGDGHYVMDGKVRIDQVNSLLGASIQEDVDTIGGLILKENID
IEAGESIRIGSYTIKVLKMDGRLIKQIDIKEEAGNTTGITAHHKLPLPEPVMLNSATLSEK

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains

Homologues:

Organism=Homo sapiens, GI310128564, Length=397, Percent_Identity=46.5994962216625, Blast_Score=374, Evalue=1e-103,
Organism=Escherichia coli, GI145693175, Length=418, Percent_Identity=26.555023923445, Blast_Score=147, Evalue=2e-36,
Organism=Escherichia coli, GI1790664, Length=452, Percent_Identity=23.2300884955752, Blast_Score=131, Evalue=9e-32,
Organism=Escherichia coli, GI1786879, Length=257, Percent_Identity=33.4630350194552, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI87082033, Length=275, Percent_Identity=26.9090909090909, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI1788119, Length=243, Percent_Identity=28.3950617283951, Blast_Score=84, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17539402, Length=256, Percent_Identity=27.734375, Blast_Score=65, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YHDT_BACSU (O07589)

Other databases:

- EMBL:   Y14082
- EMBL:   AL009126
- PIR:   B69827
- RefSeq:   NP_388840.1
- ProteinModelPortal:   O07589
- EnsemblBacteria:   EBBACT00000001364
- GeneID:   936275
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU09590
- NMPDR:   fig|224308.1.peg.959
- GenoList:   BSU09590
- GeneTree:   EBGT00070000032069
- HOGENOM:   HBG673071
- OMA:   VRVYPKT
- PhylomeDB:   O07589
- ProtClustDB:   CLSK886967
- BioCyc:   BSUB:BSU09590-MONOMER
- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170
- Gene3D:   G3DSA:3.30.465.10
- SMART:   SM00116

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21

EC number: NA

Molecular weight: Translated: 51521; Mature: 51521

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: PS51371 CBS

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xdc11ba4)-; HASH(0xc3f3984)-; HASH(0xdcda4a4)-;

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDDIDSLILIGVLIALTAFFVASEFAIVRVRRSRIDQLITEGNKRAILARRVITDLDEYL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
SASQLGITLTSIGLGVLGEPAFERLLHPLFEPLGLPDSVSHAVSFAVAYGLITFLHVVVG
HHHHCCEEHHHHCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
ELAPKTVAIQKAEQLTLLIAGPLRLFYLLLFPFIWILNGSARLLCGMFGLKPASEHDGSH
HCCCCHHHHHHHHHEEEEEECHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCC
SEEELRMLLSESLKNGEINPSEYKYVNKIFEFDNRIAKEIMIPRKEMAAVSTEMTMAEML
CHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
EVMLKEKYTRWPVTDGDKDSVLGLVNTKHLFSDLLFMTEEERMKMTIHPYVRPVIEVIET
HHHHHHHCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHCCHHHHEEEECHHHHHHHHHHHH
IPVHDLLIKMQRERIHMAILSDEYGGTSGLVTTEDILEEIVGEIRDEFDEDEQPLIQKLG
CCHHHHHHHHHHHHHHEEEEECCCCCCCCCEEHHHHHHHHHHHHHHHCCCCCHHHHHHCC
DGHYVMDGKVRIDQVNSLLGASIQEDVDTIGGLILKENIDIEAGESIRIGSYTIKVLKMD
CCCEEEECEEEHHHHHHHHCCHHHHHHHHHCCEEEEECCCCCCCCEEEECCEEEEEEEEC
GRLIKQIDIKEEAGNTTGITAHHKLPLPEPVMLNSATLSEK
CHHHHHCCCHHHCCCCCCEEEECCCCCCCCCEECCCCCCCH
>Mature Secondary Structure
MDDIDSLILIGVLIALTAFFVASEFAIVRVRRSRIDQLITEGNKRAILARRVITDLDEYL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
SASQLGITLTSIGLGVLGEPAFERLLHPLFEPLGLPDSVSHAVSFAVAYGLITFLHVVVG
HHHHCCEEHHHHCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
ELAPKTVAIQKAEQLTLLIAGPLRLFYLLLFPFIWILNGSARLLCGMFGLKPASEHDGSH
HCCCCHHHHHHHHHEEEEEECHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCC
SEEELRMLLSESLKNGEINPSEYKYVNKIFEFDNRIAKEIMIPRKEMAAVSTEMTMAEML
CHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
EVMLKEKYTRWPVTDGDKDSVLGLVNTKHLFSDLLFMTEEERMKMTIHPYVRPVIEVIET
HHHHHHHCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHCCHHHHEEEECHHHHHHHHHHHH
IPVHDLLIKMQRERIHMAILSDEYGGTSGLVTTEDILEEIVGEIRDEFDEDEQPLIQKLG
CCHHHHHHHHHHHHHHEEEEECCCCCCCCCEEHHHHHHHHHHHHHHHCCCCCHHHHHHCC
DGHYVMDGKVRIDQVNSLLGASIQEDVDTIGGLILKENIDIEAGESIRIGSYTIKVLKMD
CCCEEEECEEEHHHHHHHHCCHHHHHHHHHCCEEEEECCCCCCCCEEEECCEEEEEEEEC
GRLIKQIDIKEEAGNTTGITAHHKLPLPEPVMLNSATLSEK
CHHHHHCCCHHHCCCCCCEEEECCCCCCCCCEECCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377