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The map label for this gene is yhdR

Identifier: 16078022

GI number: 16078022

Start: 1034046

End: 1035227

Strand: Direct

Name: yhdR

Synonym: BSU09570

Alternate gene names: 16078022

Gene position: 1034046-1035227 (Clockwise)

Preceding gene: 16078019

Following gene: 16078024

Centisome position: 24.53

GC content: 45.26

Gene sequence:

>1182_bases
ATGAAATTGGCTGGGTTATCCCGGGAAGTTGAAGAAAACTTAAATAAAGGATCATGGATTCGCAAGCTGTTTGATGAAGG
TGCAAGGCTGAAGAAGGAGTTCGGGGAAGACCAGGTATTTGATTTTTCACTCGGCAACCCGATTGTTGAACCGCCTGAAG
CTTTTAAGAGAGCGTTAATAGAGGAAGCTGAAAAAGGCAGCCACGGATACATACAAAACCAAGGGCTTCTTGCAGCGAGA
GAAAAAGTCGCGCAATTTCTGGGCTCGCGTTTTGAAGCTGATTTCTCAGCGGAGCGCATCGTCATGACGGTGGGCGCGGG
AGGCGCTTTGAATGTTGCGTTAAAAAGCATCGTAAACCCTGGGGAAGAGGTCATTATTCTTGCACCTTATTTTGCCGAAT
ATAAGTTGTATATTGAGAACTACGGGGGAAAAGCCGTCAGCTGCCCGTTGACAAGCCGGTTTGAGATCGACATTGAAGCG
GTAAGGCAATCGATCACTCCACAGACGAAAGGGCTGATTCTCAATACACCGCATAACCCCACAGGCACTGTTCTCAGCCA
GAAAAATATAGACGATTTAGGCGCTTTATTAAAAGAAATAGAAGAGAAGAGCGGCCAGACGATTTATGTGCTGTTTGATG
AACCGTACAGTCAATTAATCTATGATGAAGAGCTGGCAAATCCGTTTCAATCGTACCATCGTGTGATATTGGCCAGCTCA
TTCAGTAAAGATCTCGGCATAGCCGGAGAGCGGCTCGGGTATATCGGATTGGACAGCCGAATGCCGGATGCGGACCTTTT
GATCAACGCTTTTGTGTATTGTAATCGAACGCTTGGATTTGTGAATGCCCCTGTCATGATGCAGCGGGCTGTGGCACGAA
TGGATGATTTAAGAGTAGACGCGAGCGCTTATAAAGAGCGCCGGGATTTAATGGTAGACATTTTAAAAGAAGCCGGTTTT
GAATTTGAAATGCCAAAGGGAGGTTTCTTTGTTTTTCCGAAATCGCCGATTGAAGATGAAGTTGCATTTTGCGTGCATGC
CGCCCAAAAATACAAATTATTAATTGTGCCGAGCAGCGGTTTTGGAATGAGCGGGCATTTCCGATTATCCTTCAGTGTGC
CGATCGAGCAGATTAAAAACTCACGGGACATTTTCATTTCTTTATATAAAGATTTTGCTTAA

Upstream 100 bases:

>100_bases
TGTTTTTTTTAGACCGGAATTGGAAGTTGTGGAATTCATCATCTGATTGAAGTAACATAGGAAGATAGAATTTTCAAATT
TTTATATGCGGAAGGGACAG

Downstream 100 bases:

>100_bases
GAAGGCAAAGAAAAGAAAACAGTTTTCAAGGCTGTTTTCTTTTTATATCCGCAAAATCCTTCCTCTTCCAATCCAGACAG
GCGCAGAATTGACAAGCAGG

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A

Number of amino acids: Translated: 393; Mature: 393

Protein sequence:

>393_residues
MKLAGLSREVEENLNKGSWIRKLFDEGARLKKEFGEDQVFDFSLGNPIVEPPEAFKRALIEEAEKGSHGYIQNQGLLAAR
EKVAQFLGSRFEADFSAERIVMTVGAGGALNVALKSIVNPGEEVIILAPYFAEYKLYIENYGGKAVSCPLTSRFEIDIEA
VRQSITPQTKGLILNTPHNPTGTVLSQKNIDDLGALLKEIEEKSGQTIYVLFDEPYSQLIYDEELANPFQSYHRVILASS
FSKDLGIAGERLGYIGLDSRMPDADLLINAFVYCNRTLGFVNAPVMMQRAVARMDDLRVDASAYKERRDLMVDILKEAGF
EFEMPKGGFFVFPKSPIEDEVAFCVHAAQKYKLLIVPSSGFGMSGHFRLSFSVPIEQIKNSRDIFISLYKDFA

Sequences:

>Translated_393_residues
MKLAGLSREVEENLNKGSWIRKLFDEGARLKKEFGEDQVFDFSLGNPIVEPPEAFKRALIEEAEKGSHGYIQNQGLLAAR
EKVAQFLGSRFEADFSAERIVMTVGAGGALNVALKSIVNPGEEVIILAPYFAEYKLYIENYGGKAVSCPLTSRFEIDIEA
VRQSITPQTKGLILNTPHNPTGTVLSQKNIDDLGALLKEIEEKSGQTIYVLFDEPYSQLIYDEELANPFQSYHRVILASS
FSKDLGIAGERLGYIGLDSRMPDADLLINAFVYCNRTLGFVNAPVMMQRAVARMDDLRVDASAYKERRDLMVDILKEAGF
EFEMPKGGFFVFPKSPIEDEVAFCVHAAQKYKLLIVPSSGFGMSGHFRLSFSVPIEQIKNSRDIFISLYKDFA
>Mature_393_residues
MKLAGLSREVEENLNKGSWIRKLFDEGARLKKEFGEDQVFDFSLGNPIVEPPEAFKRALIEEAEKGSHGYIQNQGLLAAR
EKVAQFLGSRFEADFSAERIVMTVGAGGALNVALKSIVNPGEEVIILAPYFAEYKLYIENYGGKAVSCPLTSRFEIDIEA
VRQSITPQTKGLILNTPHNPTGTVLSQKNIDDLGALLKEIEEKSGQTIYVLFDEPYSQLIYDEELANPFQSYHRVILASS
FSKDLGIAGERLGYIGLDSRMPDADLLINAFVYCNRTLGFVNAPVMMQRAVARMDDLRVDASAYKERRDLMVDILKEAGF
EFEMPKGGFFVFPKSPIEDEVAFCVHAAQKYKLLIVPSSGFGMSGHFRLSFSVPIEQIKNSRDIFISLYKDFA

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family

Homologues:

Organism=Homo sapiens, GI95147551, Length=331, Percent_Identity=25.6797583081571, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI169881279, Length=331, Percent_Identity=25.6797583081571, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI56713254, Length=400, Percent_Identity=23.25, Blast_Score=89, Evalue=9e-18,
Organism=Homo sapiens, GI56713256, Length=400, Percent_Identity=23.25, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI4507369, Length=233, Percent_Identity=25.7510729613734, Blast_Score=87, Evalue=2e-17,
Organism=Escherichia coli, GI1786816, Length=348, Percent_Identity=28.735632183908, Blast_Score=112, Evalue=5e-26,
Organism=Escherichia coli, GI1788627, Length=371, Percent_Identity=25.8760107816712, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI1788722, Length=371, Percent_Identity=25.0673854447439, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1787710, Length=226, Percent_Identity=26.1061946902655, Blast_Score=66, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17567663, Length=385, Percent_Identity=24.1558441558442, Blast_Score=90, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17567369, Length=328, Percent_Identity=26.219512195122, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI71994476, Length=330, Percent_Identity=25.1515151515152, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71994472, Length=330, Percent_Identity=25.1515151515152, Blast_Score=84, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6322401, Length=306, Percent_Identity=24.1830065359477, Blast_Score=89, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6323118, Length=403, Percent_Identity=27.2952853598015, Blast_Score=79, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6320317, Length=407, Percent_Identity=26.5356265356265, Blast_Score=70, Evalue=6e-13,
Organism=Drosophila melanogaster, GI28573069, Length=260, Percent_Identity=26.1538461538462, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24646114, Length=260, Percent_Identity=26.1538461538462, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI28573067, Length=260, Percent_Identity=26.1538461538462, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI28573065, Length=260, Percent_Identity=26.1538461538462, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI18859735, Length=392, Percent_Identity=21.9387755102041, Blast_Score=75, Evalue=8e-14,
Organism=Drosophila melanogaster, GI45551451, Length=458, Percent_Identity=23.7991266375546, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24641770, Length=458, Percent_Identity=23.7991266375546, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24641760, Length=458, Percent_Identity=23.7991266375546, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24641768, Length=458, Percent_Identity=23.7991266375546, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24641766, Length=458, Percent_Identity=23.7991266375546, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24641764, Length=458, Percent_Identity=23.7991266375546, Blast_Score=69, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AAT3_BACSU (O07587)

Other databases:

- EMBL:   Y14082
- EMBL:   AL009126
- PIR:   H69826
- RefSeq:   NP_388838.1
- ProteinModelPortal:   O07587
- SMR:   O07587
- EnsemblBacteria:   EBBACT00000002531
- GeneID:   939752
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU09570
- NMPDR:   fig|224308.1.peg.957
- GenoList:   BSU09570
- GeneTree:   EBGT00070000031804
- HOGENOM:   HBG645860
- OMA:   DEPYAKI
- ProtClustDB:   PRK06836
- BioCyc:   BSUB:BSU09570-MONOMER
- GO:   GO:0005737
- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- Gene3D:   G3DSA:3.40.640.10
- Gene3D:   G3DSA:3.90.1150.10
- PRINTS:   PR00753

Pfam domain/function: PF00155 Aminotran_1_2; SSF53383 PyrdxlP-dep_Trfase_major

EC number: =2.6.1.1

Molecular weight: Translated: 43889; Mature: 43889

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLAGLSREVEENLNKGSWIRKLFDEGARLKKEFGEDQVFDFSLGNPIVEPPEAFKRALI
CCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHH
EEAEKGSHGYIQNQGLLAAREKVAQFLGSRFEADFSAERIVMTVGAGGALNVALKSIVNP
HHHCCCCCCEEECCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHCCC
GEEVIILAPYFAEYKLYIENYGGKAVSCPLTSRFEIDIEAVRQSITPQTKGLILNTPHNP
CCCEEEECCCCEEEEEEEEECCCCEEECCCCCCEEEEHHHHHHHCCCCCCCEEEECCCCC
TGTVLSQKNIDDLGALLKEIEEKSGQTIYVLFDEPYSQLIYDEELANPFQSYHRVILASS
CCCEEECCCHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHC
FSKDLGIAGERLGYIGLDSRMPDADLLINAFVYCNRTLGFVNAPVMMQRAVARMDDLRVD
CCCCCCCCCHHCEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCC
ASAYKERRDLMVDILKEAGFEFEMPKGGFFVFPKSPIEDEVAFCVHAAQKYKLLIVPSSG
HHHHHHHHHHHHHHHHHCCCEEECCCCCEEEECCCCCHHHHHHHHHHHCCEEEEEEECCC
FGMSGHFRLSFSVPIEQIKNSRDIFISLYKDFA
CCCCCEEEEEECCCHHHCCCCCCEEEEEEHHCC
>Mature Secondary Structure
MKLAGLSREVEENLNKGSWIRKLFDEGARLKKEFGEDQVFDFSLGNPIVEPPEAFKRALI
CCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHH
EEAEKGSHGYIQNQGLLAAREKVAQFLGSRFEADFSAERIVMTVGAGGALNVALKSIVNP
HHHCCCCCCEEECCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHCCC
GEEVIILAPYFAEYKLYIENYGGKAVSCPLTSRFEIDIEAVRQSITPQTKGLILNTPHNP
CCCEEEECCCCEEEEEEEEECCCCEEECCCCCCEEEEHHHHHHHCCCCCCCEEEECCCCC
TGTVLSQKNIDDLGALLKEIEEKSGQTIYVLFDEPYSQLIYDEELANPFQSYHRVILASS
CCCEEECCCHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHC
FSKDLGIAGERLGYIGLDSRMPDADLLINAFVYCNRTLGFVNAPVMMQRAVARMDDLRVD
CCCCCCCCCHHCEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCC
ASAYKERRDLMVDILKEAGFEFEMPKGGFFVFPKSPIEDEVAFCVHAAQKYKLLIVPSSG
HHHHHHHHHHHHHHHHHCCCEEECCCCCEEEECCCCCHHHHHHHHHHHCCEEEEEEECCC
FGMSGHFRLSFSVPIEQIKNSRDIFISLYKDFA
CCCCCEEEEEECCCHHHCCCCCCEEEEEEHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377