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The map label for this gene is yhcZ

Identifier: 16077998

GI number: 16077998

Start: 1009804

End: 1010448

Strand: Direct

Name: yhcZ

Synonym: BSU09330

Alternate gene names: 16077998

Gene position: 1009804-1010448 (Clockwise)

Preceding gene: 16077997

Following gene: 16077999

Centisome position: 23.95

GC content: 43.72

Gene sequence:

>645_bases
ATGAAAATTGTCATTGCTGATGATCATCATGTTGTCAGAAAGGGTCTGCGTTTTTTCTTTGCCACCCAGGATGATATTGA
AGTCGTCGGAGAAGCTGCAACTGGATTAGAAGCCCTCCGTGTCATCGAAGAGACAAAGCCGGATCTTGTGCTAATGGATT
TGTCTATGCCCGAGATGGACGGCATTCAAGCCATTAAAAAAGCAATACAGCAATTTCCGGATACGAATATCATTGTGCTG
ACGAGCTACTCTGATCAGGAGCACGTCATCCCCGCGCTTCAGGCAGGCGCGAAGGCGTATCAATTAAAGGATACGGAGCC
CGAGGAATTGGTGAAAACACGACAAGTGCATGGTGGCGAATACAAGCTTTCTACAGCTATTATGCCCCATGTGCTGACAC
ATATGAAAAATCAGCACGACCCGGAAAAAGAAAAATACTATCAATTAACTAGAAGGGAAAAAGACGTTCTGACTGAAATA
GCGAACGGGAAAAGCAATAAAGAAATCGCAGCAGCCTTGTTTATTTCAGAAAAAACAGTAAAAACCCATGTATCGAATCT
TTTAGCAAAACTTGAAGTGGCCGATCGCACGCAAGCAGCGCTTTTCGCAGTGAAATATAACCTGAATGGAGAGATCTCAA
AATGA

Upstream 100 bases:

>100_bases
CGGAAAAAGCCGGAGCTAAGTTTTGGATTGAGTCAGCGCTTGGAACTGGAACAAAGCTGTCCATCAGGCTTCCGCTAAAA
AGCCGAAAAGGAGGGGCGGT

Downstream 100 bases:

>100_bases
ACATGTTAGTCATAAATGGCACGCCAAGAAAACATGGCAGAACAAGAATTGCAGCATCCTATATTGCAGCTCTGTATCAC
ACGGATTTGATTGATCTAAG

Product: two-component response regulator YhcY

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 214; Mature: 214

Protein sequence:

>214_residues
MKIVIADDHHVVRKGLRFFFATQDDIEVVGEAATGLEALRVIEETKPDLVLMDLSMPEMDGIQAIKKAIQQFPDTNIIVL
TSYSDQEHVIPALQAGAKAYQLKDTEPEELVKTRQVHGGEYKLSTAIMPHVLTHMKNQHDPEKEKYYQLTRREKDVLTEI
ANGKSNKEIAAALFISEKTVKTHVSNLLAKLEVADRTQAALFAVKYNLNGEISK

Sequences:

>Translated_214_residues
MKIVIADDHHVVRKGLRFFFATQDDIEVVGEAATGLEALRVIEETKPDLVLMDLSMPEMDGIQAIKKAIQQFPDTNIIVL
TSYSDQEHVIPALQAGAKAYQLKDTEPEELVKTRQVHGGEYKLSTAIMPHVLTHMKNQHDPEKEKYYQLTRREKDVLTEI
ANGKSNKEIAAALFISEKTVKTHVSNLLAKLEVADRTQAALFAVKYNLNGEISK
>Mature_214_residues
MKIVIADDHHVVRKGLRFFFATQDDIEVVGEAATGLEALRVIEETKPDLVLMDLSMPEMDGIQAIKKAIQQFPDTNIIVL
TSYSDQEHVIPALQAGAKAYQLKDTEPEELVKTRQVHGGEYKLSTAIMPHVLTHMKNQHDPEKEKYYQLTRREKDVLTEI
ANGKSNKEIAAALFISEKTVKTHVSNLLAKLEVADRTQAALFAVKYNLNGEISK

Specific function: Member of the two-component regulatory system yhcY/yhcZ

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain

Homologues:

Organism=Escherichia coli, GI1787473, Length=201, Percent_Identity=38.3084577114428, Blast_Score=117, Evalue=7e-28,
Organism=Escherichia coli, GI1788521, Length=202, Percent_Identity=34.6534653465347, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1788222, Length=213, Percent_Identity=31.4553990610329, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1790102, Length=206, Percent_Identity=31.0679611650485, Blast_Score=94, Evalue=6e-21,
Organism=Escherichia coli, GI1788712, Length=203, Percent_Identity=27.5862068965517, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1786747, Length=194, Percent_Identity=27.8350515463918, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1787277, Length=137, Percent_Identity=35.7664233576642, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1788550, Length=109, Percent_Identity=39.4495412844037, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI87082052, Length=113, Percent_Identity=30.9734513274336, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1789937, Length=207, Percent_Identity=25.6038647342995, Blast_Score=64, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YHCZ_BACSU (O07528)

Other databases:

- EMBL:   Y14079
- EMBL:   AL009126
- PIR:   F69824
- RefSeq:   NP_388814.1
- HSSP:   P11470
- ProteinModelPortal:   O07528
- SMR:   O07528
- EnsemblBacteria:   EBBACT00000001200
- GeneID:   939750
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU09330
- NMPDR:   fig|224308.1.peg.933
- GenoList:   BSU09330
- GeneTree:   EBGT00070000031892
- HOGENOM:   HBG753323
- OMA:   DQEHVIP
- PhylomeDB:   O07528
- ProtClustDB:   CLSK886949
- BioCyc:   BSUB:BSU09330-MONOMER
- GO:   GO:0005737
- InterPro:   IPR011006
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- PRINTS:   PR00038
- SMART:   SM00421
- SMART:   SM00448

Pfam domain/function: PF00196 GerE; PF00072 Response_reg; SSF52172 CheY_like

EC number: NA

Molecular weight: Translated: 24023; Mature: 24023

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: PS00622 HTH_LUXR_1; PS50043 HTH_LUXR_2; PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIVIADDHHVVRKGLRFFFATQDDIEVVGEAATGLEALRVIEETKPDLVLMDLSMPEMD
CEEEEECCHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCH
GIQAIKKAIQQFPDTNIIVLTSYSDQEHVIPALQAGAKAYQLKDTEPEELVKTRQVHGGE
HHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHCCCCEEECCCCCHHHHHHHHHHCCCC
YKLSTAIMPHVLTHMKNQHDPEKEKYYQLTRREKDVLTEIANGKSNKEIAAALFISEKTV
EEEHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHEEHHHHHHHHH
KTHVSNLLAKLEVADRTQAALFAVKYNLNGEISK
HHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCC
>Mature Secondary Structure
MKIVIADDHHVVRKGLRFFFATQDDIEVVGEAATGLEALRVIEETKPDLVLMDLSMPEMD
CEEEEECCHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCH
GIQAIKKAIQQFPDTNIIVLTSYSDQEHVIPALQAGAKAYQLKDTEPEELVKTRQVHGGE
HHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHCCCCEEECCCCCHHHHHHHHHHCCCC
YKLSTAIMPHVLTHMKNQHDPEKEKYYQLTRREKDVLTEIANGKSNKEIAAALFISEKTV
EEEHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHEEHHHHHHHHH
KTHVSNLLAKLEVADRTQAALFAVKYNLNGEISK
HHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377