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The map label for this gene is yhcY

Identifier: 16077997

GI number: 16077997

Start: 1008668

End: 1009807

Strand: Direct

Name: yhcY

Synonym: BSU09320

Alternate gene names: 16077997

Gene position: 1008668-1009807 (Clockwise)

Preceding gene: 255767219

Following gene: 16077998

Centisome position: 23.93

GC content: 45.96

Gene sequence:

>1140_bases
GTGAGCAAAACGAGGATGGAAAAATTAAAAACGCTGAAAACGATTGCGGAAACCTTAAATCAAGGGCACGATATCAAAGC
AACACTGGATGAGGTTTTAAAAGAGTTGCTGAGTCTGACAAACCTTCAATCCGGATGGATTTTTCTGATCGAAGAAGATG
GGTCTTATACGTTAGCGGCCGACGCTTATCTGCCCCCGGCTTTAAGCCGCAAGGAAAAAGTGCTGATGTGCGAAGGGGAG
TGTTACTGCCTGACGAAATTCAATAACGGAGGGCTTAGAAAAGCTGCAAATATCATGAACTGCAAACGCATCGAATCAGC
AGAAAACCTGCATTGTTTTGACACAGAAGGGATTACGCATCATGCAACTGTGCCTTTAGAAGACGGGGACAGAAGATTCG
GATTGTTAAATGTAGCGGCGGCCGGAAAAACCATGTTTGATGAGGAAGAGCTGCATTTACTCGAGTCTGTCGCCTTTCAG
ATCGGAACGGCAATCCAGCGTATGAGGCTTTCTGAATATCAACAAAAAAATGCTCTTTTAATGGAGCGTAACCGCCTCGC
TCAGGAGCTTCACGATTCAGTCAATCAAATGCTGTTTTCCGTCAGTTTAACTGCCAAAGCTGCGAAGACACTAACAAAAG
ATGAAAATTTACAGCAGATGATTGATTTCATCCAAAACCTATCACAGGACGCGCTCGCAGAAATGAAAGCGTTAATTTGG
CAGCTTCGCCCCGGAGGATTGGAAAAAGGGCTGGCTGAAGCCATTAAAAGCTATGGTGCGCTCATTGGATTGAAGATCAT
TTTTACACAAAAAGGCTGTCCTGTTCTGACTGATGAGCAGGAGCATATGCTATGGCGTGTCGTACAGGAAGCTTTAAATA
ACTGCAAAAAGCATGCCGGAACGGATACGGCGTATGTTAGTCTGACTGCTTCTTTGTGCCATGCGGAGCTGGATATCATC
GATCATGGGGCAGGATTTCGCTATGAAGCGCATGCCGGTCTGCCTTCACTTGGCATAAAAGGTATGAAAGAGCGAGCGGA
AAAAGCCGGAGCTAAGTTTTGGATTGAGTCAGCGCTTGGAACTGGAACAAAGCTGTCCATCAGGCTTCCGCTAAAAAGCC
GAAAAGGAGGGGCGGTATGA

Upstream 100 bases:

>100_bases
TCATCCAAAAGTCTGAAAGAAAATCATCCTACAAGTGAAGCAATGAAATACAAAAAACTGGTATAATCTTAAATACAAGA
TCAATGCCGGAGTGAGAAAC

Downstream 100 bases:

>100_bases
AAATTGTCATTGCTGATGATCATCATGTTGTCAGAAAGGGTCTGCGTTTTTTCTTTGCCACCCAGGATGATATTGAAGTC
GTCGGAGAAGCTGCAACTGG

Product: two-component sensor histidine kinase YhcZ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 379; Mature: 378

Protein sequence:

>379_residues
MSKTRMEKLKTLKTIAETLNQGHDIKATLDEVLKELLSLTNLQSGWIFLIEEDGSYTLAADAYLPPALSRKEKVLMCEGE
CYCLTKFNNGGLRKAANIMNCKRIESAENLHCFDTEGITHHATVPLEDGDRRFGLLNVAAAGKTMFDEEELHLLESVAFQ
IGTAIQRMRLSEYQQKNALLMERNRLAQELHDSVNQMLFSVSLTAKAAKTLTKDENLQQMIDFIQNLSQDALAEMKALIW
QLRPGGLEKGLAEAIKSYGALIGLKIIFTQKGCPVLTDEQEHMLWRVVQEALNNCKKHAGTDTAYVSLTASLCHAELDII
DHGAGFRYEAHAGLPSLGIKGMKERAEKAGAKFWIESALGTGTKLSIRLPLKSRKGGAV

Sequences:

>Translated_379_residues
MSKTRMEKLKTLKTIAETLNQGHDIKATLDEVLKELLSLTNLQSGWIFLIEEDGSYTLAADAYLPPALSRKEKVLMCEGE
CYCLTKFNNGGLRKAANIMNCKRIESAENLHCFDTEGITHHATVPLEDGDRRFGLLNVAAAGKTMFDEEELHLLESVAFQ
IGTAIQRMRLSEYQQKNALLMERNRLAQELHDSVNQMLFSVSLTAKAAKTLTKDENLQQMIDFIQNLSQDALAEMKALIW
QLRPGGLEKGLAEAIKSYGALIGLKIIFTQKGCPVLTDEQEHMLWRVVQEALNNCKKHAGTDTAYVSLTASLCHAELDII
DHGAGFRYEAHAGLPSLGIKGMKERAEKAGAKFWIESALGTGTKLSIRLPLKSRKGGAV
>Mature_378_residues
SKTRMEKLKTLKTIAETLNQGHDIKATLDEVLKELLSLTNLQSGWIFLIEEDGSYTLAADAYLPPALSRKEKVLMCEGEC
YCLTKFNNGGLRKAANIMNCKRIESAENLHCFDTEGITHHATVPLEDGDRRFGLLNVAAAGKTMFDEEELHLLESVAFQI
GTAIQRMRLSEYQQKNALLMERNRLAQELHDSVNQMLFSVSLTAKAAKTLTKDENLQQMIDFIQNLSQDALAEMKALIWQ
LRPGGLEKGLAEAIKSYGALIGLKIIFTQKGCPVLTDEQEHMLWRVVQEALNNCKKHAGTDTAYVSLTASLCHAELDIID
HGAGFRYEAHAGLPSLGIKGMKERAEKAGAKFWIESALGTGTKLSIRLPLKSRKGGAV

Specific function: Member of the two-component regulatory system yhcY/yhcZ. Probably activates yhcZ by phosphorylation

COG id: COG4585

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YHCY_BACSU (O07527)

Other databases:

- EMBL:   Y14079
- EMBL:   AL009126
- PIR:   E69824
- RefSeq:   NP_388813.1
- ProteinModelPortal:   O07527
- EnsemblBacteria:   EBBACT00000003984
- GeneID:   939760
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU09320
- NMPDR:   fig|224308.1.peg.932
- GenoList:   BSU09320
- GeneTree:   EBGT00070000031901
- HOGENOM:   HBG338669
- OMA:   EGITHHA
- ProtClustDB:   CLSK885603
- BioCyc:   BSUB:BSU09320-MONOMER
- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR011712
- Gene3D:   G3DSA:3.30.565.10
- SMART:   SM00065
- SMART:   SM00387

Pfam domain/function: PF01590 GAF; PF02518 HATPase_c; PF07730 HisKA_3; SSF55874 ATP_bd_ATPase

EC number: =2.7.13.3

Molecular weight: Translated: 41991; Mature: 41860

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKTRMEKLKTLKTIAETLNQGHDIKATLDEVLKELLSLTNLQSGWIFLIEEDGSYTLAA
CCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCEEEEE
DAYLPPALSRKEKVLMCEGECYCLTKFNNGGLRKAANIMNCKRIESAENLHCFDTEGITH
CCCCCCCCCCCCEEEEECCCEEEEEEECCCCHHHHHHHHHHHHHCCCCCCEEECCCCCCE
HATVPLEDGDRRFGLLNVAAAGKTMFDEEELHLLESVAFQIGTAIQRMRLSEYQQKNALL
EEEECCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MERNRLAQELHDSVNQMLFSVSLTAKAAKTLTKDENLQQMIDFIQNLSQDALAEMKALIW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHH
QLRPGGLEKGLAEAIKSYGALIGLKIIFTQKGCPVLTDEQEHMLWRVVQEALNNCKKHAG
HCCCCCCHHHHHHHHHHHHHHEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
TDTAYVSLTASLCHAELDIIDHGAGFRYEAHAGLPSLGIKGMKERAEKAGAKFWIESALG
CCHHEEEHHHHHHHHHHHEEECCCCCEEECCCCCCCCCCHHHHHHHHHCCHHEEHHHHCC
TGTKLSIRLPLKSRKGGAV
CCCEEEEEECCCCCCCCCC
>Mature Secondary Structure 
SKTRMEKLKTLKTIAETLNQGHDIKATLDEVLKELLSLTNLQSGWIFLIEEDGSYTLAA
CHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCEEEEE
DAYLPPALSRKEKVLMCEGECYCLTKFNNGGLRKAANIMNCKRIESAENLHCFDTEGITH
CCCCCCCCCCCCEEEEECCCEEEEEEECCCCHHHHHHHHHHHHHCCCCCCEEECCCCCCE
HATVPLEDGDRRFGLLNVAAAGKTMFDEEELHLLESVAFQIGTAIQRMRLSEYQQKNALL
EEEECCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MERNRLAQELHDSVNQMLFSVSLTAKAAKTLTKDENLQQMIDFIQNLSQDALAEMKALIW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHH
QLRPGGLEKGLAEAIKSYGALIGLKIIFTQKGCPVLTDEQEHMLWRVVQEALNNCKKHAG
HCCCCCCHHHHHHHHHHHHHHEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
TDTAYVSLTASLCHAELDIIDHGAGFRYEAHAGLPSLGIKGMKERAEKAGAKFWIESALG
CCHHEEEHHHHHHHHHHHEEECCCCCEEECCCCCCCCCCHHHHHHHHHCCHHEEHHHHCC
TGTKLSIRLPLKSRKGGAV
CCCEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377