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The map label for this gene is malP

Identifier: 16077887

GI number: 16077887

Start: 892215

End: 893798

Strand: Direct

Name: malP

Synonym: BSU08200

Alternate gene names: 16077887

Gene position: 892215-893798 (Clockwise)

Preceding gene: 16077886

Following gene: 16077888

Centisome position: 21.16

GC content: 47.79

Gene sequence:

>1584_bases
ATGATGCAAAAAATTCAGCGCTTTGGAAGCGCGATGTTTGTGCCTGTTTTATTATTCGCGTTCGCCGGCATTATCGTCGG
TATCAGCACGCTCTTTAAAAATAAAACCCTCATGGGACCGCTCGCCGATCCTGACGGTTTTTGGTATCAGTGCTGGTATA
TCATTGAGCAGGGCGGCTGGACTGTTTTTAACCAAATGCCGCTCTTATTCGCCATTGGCATCCCGGTTGCTTTGGCGAAG
AAAGCTCAGGCACGCGCCTGTTTGGAAGCGCTTACTGTCTACCTGACATTCAACTATTTTGTCAGCGCGATATTGACGGT
ATGGGGAGGAGCATTTGGCGTCGACATGAATCAAGAGGTCGGCGGAACGAGCGGGTTAACGATGATTGCGGGCATAAAAA
CGCTCGATACCAACATCATCGGAGCCATCTTTATTTCTTCGATTGTCGTCTTTTTGCATAATCGCTATTTTGATAAAAAA
CTGCCCGATTTTCTCGGCATCTTTCAAGGCTCAACATATATCGTGATGATTTCCTTCTTTATTATGATCCCAATTGCGTT
GGCTGTGTCTTATATTTGGCCGATGGTTCAATCGGGAATCGGCTCGCTTCAAAGCTTCCTGGTTGCTTCTGGGGCGGTGG
GCGTTTGGATATACACGTTTTTGGAACGGATTTTAATTCCGACCGGCCTTCATCACTTTATTTACACGCCGTTTATTTAT
GGCCCGGCTGTAGCGGAAGGCGGGATCGTCACGTATTGGGCACAGCATCTCGGCGAATATTCGCAAAGCGCCAAACCGCT
GAAGGAGCTCTTTCCGCAAGGCGGATTCGCGCTTCACGGCAACTCGAAAATCTTCGGTATTCCGGGTATCGCCCTGGCTT
TTTATGTGACAGCCAAAAAGGAAAAGAAAAAACTCGTCGCAGGGCTGCTGATTCCTGTCACACTGACAGCGATTGTCGCC
GGTATTACAGAGCCGATTGAGTTTACGTTCTTATTCATTTCACCTTTCTTATTTGCGGTTCACGCCGTGCTTGCCGCCAC
AATGTCGACAGTTATGTATATGGCCGGCGTCGTCGGAAATATGGGAGGCGGACTGATTGAGGCGGTAACCTTGAACTGGA
TTCCGCTCTTTGGCAGCCACGGTATGACATATGTGTATCAAATTTTGATCGGGCTCTCGTTTACAGCAATTTATTTTTTC
GTCTTCAGATTTTTAATCCTCAAATTCAATATCGCTACACCAGGACGGGAAAAGGATGAACAGCAGGAAACAAAGCTATA
TTCGAAAAAGGAATACAGAGAACGAAAAAACAAGGATGAAACGGCCTCCGCTGCTGAAACGGCTGATGACACCGCTTTTC
TGTATATTGAAGCGCTGGGCGGAAAAGACAACATCACTGAAGTCACAAACTGCGCCACCCGCCTCAGAGTCAGTGTCAAG
GATGAAACAAAGGTTGAACCCGACAGCGTATTCCGCGCGCTTGGCGCACACGGCGTTGTCAGGAACGGGAAGGCGTTTCA
GGTAATTATCGGATTAAGCGTGCCGCAGATGCGGGAGCGTGTGGAAAAAATATTGAATCAATAA

Upstream 100 bases:

>100_bases
CTTTTGCACCGTTTTTTCTCGTTGGCGAAGCATTGTTCCGCGCATATGTTGATTACAAAGAGGCAGAAAAAAATGACAAT
GAGTAGCAGGGGGTTCTGGT

Downstream 100 bases:

>100_bases
AGACTGCCCTCCTTTTCGGGAGGGTTTTCGTTTGCCGTCAAAAAGACCGCCATAGTAAAGTAAAGAAAGAGACAATCGAG
TAAAAAGGGGTTTGGAGGCT

Product: phosphotransferase system (PTS) maltose-specific enzyme IICB component

Products: NA

Alternate protein names: Maltose permease IIC component; PTS system maltose-specific EIIC component; Maltose-specific phosphotransferase enzyme IIB component; PTS system maltose-specific EIIB component

Number of amino acids: Translated: 527; Mature: 527

Protein sequence:

>527_residues
MMQKIQRFGSAMFVPVLLFAFAGIIVGISTLFKNKTLMGPLADPDGFWYQCWYIIEQGGWTVFNQMPLLFAIGIPVALAK
KAQARACLEALTVYLTFNYFVSAILTVWGGAFGVDMNQEVGGTSGLTMIAGIKTLDTNIIGAIFISSIVVFLHNRYFDKK
LPDFLGIFQGSTYIVMISFFIMIPIALAVSYIWPMVQSGIGSLQSFLVASGAVGVWIYTFLERILIPTGLHHFIYTPFIY
GPAVAEGGIVTYWAQHLGEYSQSAKPLKELFPQGGFALHGNSKIFGIPGIALAFYVTAKKEKKKLVAGLLIPVTLTAIVA
GITEPIEFTFLFISPFLFAVHAVLAATMSTVMYMAGVVGNMGGGLIEAVTLNWIPLFGSHGMTYVYQILIGLSFTAIYFF
VFRFLILKFNIATPGREKDEQQETKLYSKKEYRERKNKDETASAAETADDTAFLYIEALGGKDNITEVTNCATRLRVSVK
DETKVEPDSVFRALGAHGVVRNGKAFQVIIGLSVPQMRERVEKILNQ

Sequences:

>Translated_527_residues
MMQKIQRFGSAMFVPVLLFAFAGIIVGISTLFKNKTLMGPLADPDGFWYQCWYIIEQGGWTVFNQMPLLFAIGIPVALAK
KAQARACLEALTVYLTFNYFVSAILTVWGGAFGVDMNQEVGGTSGLTMIAGIKTLDTNIIGAIFISSIVVFLHNRYFDKK
LPDFLGIFQGSTYIVMISFFIMIPIALAVSYIWPMVQSGIGSLQSFLVASGAVGVWIYTFLERILIPTGLHHFIYTPFIY
GPAVAEGGIVTYWAQHLGEYSQSAKPLKELFPQGGFALHGNSKIFGIPGIALAFYVTAKKEKKKLVAGLLIPVTLTAIVA
GITEPIEFTFLFISPFLFAVHAVLAATMSTVMYMAGVVGNMGGGLIEAVTLNWIPLFGSHGMTYVYQILIGLSFTAIYFF
VFRFLILKFNIATPGREKDEQQETKLYSKKEYRERKNKDETASAAETADDTAFLYIEALGGKDNITEVTNCATRLRVSVK
DETKVEPDSVFRALGAHGVVRNGKAFQVIIGLSVPQMRERVEKILNQ
>Mature_527_residues
MMQKIQRFGSAMFVPVLLFAFAGIIVGISTLFKNKTLMGPLADPDGFWYQCWYIIEQGGWTVFNQMPLLFAIGIPVALAK
KAQARACLEALTVYLTFNYFVSAILTVWGGAFGVDMNQEVGGTSGLTMIAGIKTLDTNIIGAIFISSIVVFLHNRYFDKK
LPDFLGIFQGSTYIVMISFFIMIPIALAVSYIWPMVQSGIGSLQSFLVASGAVGVWIYTFLERILIPTGLHHFIYTPFIY
GPAVAEGGIVTYWAQHLGEYSQSAKPLKELFPQGGFALHGNSKIFGIPGIALAFYVTAKKEKKKLVAGLLIPVTLTAIVA
GITEPIEFTFLFISPFLFAVHAVLAATMSTVMYMAGVVGNMGGGLIEAVTLNWIPLFGSHGMTYVYQILIGLSFTAIYFF
VFRFLILKFNIATPGREKDEQQETKLYSKKEYRERKNKDETASAAETADDTAFLYIEALGGKDNITEVTNCATRLRVSVK
DETKVEPDSVFRALGAHGVVRNGKAFQVIIGLSVPQMRERVEKILNQ

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1263

COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain

Homologues:

Organism=Escherichia coli, GI1787908, Length=539, Percent_Identity=30.6122448979592, Blast_Score=222, Evalue=4e-59,
Organism=Escherichia coli, GI1787343, Length=540, Percent_Identity=27.5925925925926, Blast_Score=206, Evalue=4e-54,
Organism=Escherichia coli, GI1786894, Length=539, Percent_Identity=28.2003710575139, Blast_Score=187, Evalue=2e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PTOCB_BACSU (P54715)

Other databases:

- EMBL:   D50543
- EMBL:   AL009126
- PIR:   G69635
- RefSeq:   NP_388701.1
- ProteinModelPortal:   P54715
- SMR:   P54715
- EnsemblBacteria:   EBBACT00000002032
- GeneID:   939713
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU08200
- NMPDR:   fig|224308.1.peg.820
- GenoList:   BSU08200
- GeneTree:   EBGT00050000000032
- HOGENOM:   HBG571563
- OMA:   HESDHES
- PhylomeDB:   P54715
- ProtClustDB:   CLSK2517926
- BioCyc:   BSUB:BSU08200-MONOMER
- BRENDA:   2.7.1.69
- InterPro:   IPR018113
- InterPro:   IPR004719
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013
- InterPro:   IPR011535
- InterPro:   IPR010975
- Gene3D:   G3DSA:3.30.1360.60
- TIGRFAMs:   TIGR00826
- TIGRFAMs:   TIGR00852
- TIGRFAMs:   TIGR02005

Pfam domain/function: PF00367 PTS_EIIB; PF02378 PTS_EIIC; SSF55604 PTS_EIIB

EC number: =2.7.1.69

Molecular weight: Translated: 58056; Mature: 58056

Theoretical pI: Translated: 9.02; Mature: 9.02

Prosite motif: PS51098 PTS_EIIB_TYPE_1; PS01035 PTS_EIIB_TYPE_1_CYS; PS51103 PTS_EIIC_TYPE_1

Important sites: ACT_SITE 471-471

Signals:

None

Transmembrane regions:

HASH(0xd71cd4c)-; HASH(0xcdeba3c)-; HASH(0xdcb6c6c)-; HASH(0xd92c8b0)-; HASH(0xd96fc00)-; HASH(0xb574b10)-; HASH(0xd6621c8)-; HASH(0xd089a08)-; HASH(0xcb1cb2c)-; HASH(0xd4015ac)-; HASH(0xd72ec0c)-; HASH(0xd64c21c)-;

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCCHHHHHHHHCCCCEEECCCEEEEEEECCCHHHHHHHHHHHCH
>Mature Secondary Structure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CCCCCCHHHHHHHHCCCCEEECCCEEEEEEECCCHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8704981; 9384377; 11489864