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The map label for this gene is malR

Identifier: 16077886

GI number: 16077886

Start: 891436

End: 892200

Strand: Direct

Name: malR

Synonym: BSU08190

Alternate gene names: 16077886

Gene position: 891436-892200 (Clockwise)

Preceding gene: 16077885

Following gene: 16077887

Centisome position: 21.15

GC content: 41.7

Gene sequence:

>765_bases
ATGCAGCTCGAAGAACTGATCAATCAGCACTACAGCAAATTGAATGACAACGATTTTCATATTTTAAAATATATATTGAA
TCATAAGCACACATGCTATCACCTTGGAATCGACGCGCTGGCCAAAGCTTGCAGTGTATCGCGTTCCTCAATTTTACGGC
TTGCCCAAAAGCTCGGTTTCAGCGGTTACAGTGAATTTCGCGTCTTTTTAAAGTGGGAAGATCAGCCGGAAGAAGGCGAG
AGTATGAGTTTTGAAAAGCTGCTTGATGATATTGAAGCAAATTTGAAGTTTTTACGGACAAAGGACATGACGGACATGTG
CCAGCTGATTGATGCAGCTGACCGCATTTTCGTCTACGGTTCTGGAAATGCGCAAAAGATATGCGCCCGCGACCTGCAAA
GAATGTTTATTCCGCGCCATCGCTATCTTATTTTGATTGAAGACACAAATGAATTTAATTTGATGCGCGATGATTTTAAA
GTGAACGATCTGTTTATCATCATTTCTCTTTCCGGAGAAACACCGGAGCTGATTCCTCAGGCAAGAATGCTTTCTGCAAA
GGGTATTCCCTTTATTTCCATTACGAATTTAAAAAACAATGTCCTCGCCCAGCTGACTCCGCATAATCTTTATGCGACAA
GCAAACCTGTGACATTAAGCGATAGAACGGAAATTGTCGCTTTTGCACCGTTTTTTCTCGTTGGCGAAGCATTGTTCCGC
GCATATGTTGATTACAAAGAGGCAGAAAAAAATGACAATGAGTAG

Upstream 100 bases:

>100_bases
CCTGAGCTTGATCAAAGCCCAACCCGCATATCATAAATGAAATTCCCCCATTTTCGAATCTGTAATTGTATATAATAGAA
AGAAAATGGGGGGATCTGAT

Downstream 100 bases:

>100_bases
CAGGGGGTTCTGGTATGATGCAAAAAATTCAGCGCTTTGGAAGCGCGATGTTTGTGCCTGTTTTATTATTCGCGTTCGCC
GGCATTATCGTCGGTATCAG

Product: transcriptional activator of the Mal operon

Products: NA

Alternate protein names: Glv operon regulatory protein

Number of amino acids: Translated: 254; Mature: 254

Protein sequence:

>254_residues
MQLEELINQHYSKLNDNDFHILKYILNHKHTCYHLGIDALAKACSVSRSSILRLAQKLGFSGYSEFRVFLKWEDQPEEGE
SMSFEKLLDDIEANLKFLRTKDMTDMCQLIDAADRIFVYGSGNAQKICARDLQRMFIPRHRYLILIEDTNEFNLMRDDFK
VNDLFIIISLSGETPELIPQARMLSAKGIPFISITNLKNNVLAQLTPHNLYATSKPVTLSDRTEIVAFAPFFLVGEALFR
AYVDYKEAEKNDNE

Sequences:

>Translated_254_residues
MQLEELINQHYSKLNDNDFHILKYILNHKHTCYHLGIDALAKACSVSRSSILRLAQKLGFSGYSEFRVFLKWEDQPEEGE
SMSFEKLLDDIEANLKFLRTKDMTDMCQLIDAADRIFVYGSGNAQKICARDLQRMFIPRHRYLILIEDTNEFNLMRDDFK
VNDLFIIISLSGETPELIPQARMLSAKGIPFISITNLKNNVLAQLTPHNLYATSKPVTLSDRTEIVAFAPFFLVGEALFR
AYVDYKEAEKNDNE
>Mature_254_residues
MQLEELINQHYSKLNDNDFHILKYILNHKHTCYHLGIDALAKACSVSRSSILRLAQKLGFSGYSEFRVFLKWEDQPEEGE
SMSFEKLLDDIEANLKFLRTKDMTDMCQLIDAADRIFVYGSGNAQKICARDLQRMFIPRHRYLILIEDTNEFNLMRDDFK
VNDLFIIISLSGETPELIPQARMLSAKGIPFISITNLKNNVLAQLTPHNLYATSKPVTLSDRTEIVAFAPFFLVGEALFR
AYVDYKEAEKNDNE

Specific function: Positive regulator of the glv operon expression, which consists of glvA, glvR and glvC

COG id: COG1737

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain

Homologues:

None

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): GLVR_BACSU (P54717)

Other databases:

- EMBL:   D50543
- EMBL:   AL009126
- PIR:   D69802
- RefSeq:   NP_388700.1
- ProteinModelPortal:   P54717
- SMR:   P54717
- EnsemblBacteria:   EBBACT00000001996
- GeneID:   939205
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU08190
- NMPDR:   fig|224308.1.peg.819
- GenoList:   BSU08190
- GeneTree:   EBGT00050000001935
- HOGENOM:   HBG338644
- OMA:   FFLVGEA
- ProtClustDB:   CLSK886886
- BioCyc:   BSUB:BSU08190-MONOMER
- InterPro:   IPR000281
- InterPro:   IPR001347
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10

Pfam domain/function: PF01418 HTH_6; PF01380 SIS

EC number: NA

Molecular weight: Translated: 29298; Mature: 29298

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: PS51071 HTH_RPIR; PS51464 SIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLEELINQHYSKLNDNDFHILKYILNHKHTCYHLGIDALAKACSVSRSSILRLAQKLGF
CCHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEECHHHHHHHHHCCHHHHHHHHHHHCC
SGYSEFRVFLKWEDQPEEGESMSFEKLLDDIEANLKFLRTKDMTDMCQLIDAADRIFVYG
CCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHEECCCHHHHHHHHHCCCEEEEEE
SGNAQKICARDLQRMFIPRHRYLILIEDTNEFNLMRDDFKVNDLFIIISLSGETPELIPQ
CCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCEEECCEEECEEEEEEEECCCCHHHCCH
ARMLSAKGIPFISITNLKNNVLAQLTPHNLYATSKPVTLSDRTEIVAFAPFFLVGEALFR
HHHHHCCCCCEEEEECCCCCEEEEECCCCEEECCCCEEECCCCCEEEEHHHHHHHHHHHH
AYVDYKEAEKNDNE
HHHHHHHHCCCCCC
>Mature Secondary Structure
MQLEELINQHYSKLNDNDFHILKYILNHKHTCYHLGIDALAKACSVSRSSILRLAQKLGF
CCHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEECHHHHHHHHHCCHHHHHHHHHHHCC
SGYSEFRVFLKWEDQPEEGESMSFEKLLDDIEANLKFLRTKDMTDMCQLIDAADRIFVYG
CCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHEECCCHHHHHHHHHCCCEEEEEE
SGNAQKICARDLQRMFIPRHRYLILIEDTNEFNLMRDDFKVNDLFIIISLSGETPELIPQ
CCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCEEECCEEECEEEEEEEECCCCHHHCCH
ARMLSAKGIPFISITNLKNNVLAQLTPHNLYATSKPVTLSDRTEIVAFAPFFLVGEALFR
HHHHHCCCCCEEEEECCCCCEEEEECCCCEEECCCCEEECCCCCEEEEHHHHHHHHHHHH
AYVDYKEAEKNDNE
HHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8704981; 9384377; 11489864