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The map label for this gene is yfmE

Identifier: 16077817

GI number: 16077817

Start: 823716

End: 824717

Strand: Reverse

Name: yfmE

Synonym: BSU07500

Alternate gene names: 16077817

Gene position: 824717-823716 (Counterclockwise)

Preceding gene: 16077818

Following gene: 16077816

Centisome position: 19.56

GC content: 49.3

Gene sequence:

>1002_bases
ATGAAGAAAACAACCAGAAAACAAAAACGCCCCTTACTGGCGATACTCATATTGGCCGTGATTTTAATCGTTCTGTCCGT
CATCAGCATTGGAATCGGTGCATTATACATTTCACCTGATGCGGTAGTGACGAATCTGCTGGGACTGGATCATTCCTTTG
AATTTATCATCCAGCAATATCGCCTTCCCCGCATTATATTAGCGATTTTGGCAGGTGCTGGACTTGCCGCTGCCGGAGCG
ATTTTACAGGGTGTGATCCGAAATCCGCTCGCTTCCCCGGACGTTGTCGGCATTTCAAAAGGCTCCGGACTTGCGGCGAT
GGCTGTGATTCTCATCTTTCCTGAGTCGCCGGTATACGTGCTTCCGTTCTCCGCATTTGCCGGAGCCGCCATTATTGCTG
TACTATTATTAATGATAGCCCGAAAAAAGAGCATTCAGCCCTCTTCACTGGCTTTATCAGGCATTGCTTTAGGCGCGGTC
TGCCACGCCGGAATGCAATATATGATGGTCAAGTTTCCAGGCGACGTGAATGCTGCACTCATTTGGCTGACAGGAAGCCT
CTGGGGAAGAAACTGGGAAGAAGTCAAGCTGCTTGCGCCATGGCTTTTGATTCTTTTTCCGATCGTCTGCATACTCATAC
CGAAGCTGGATCTTATGTCACTCGGGGATGAGCTTGCACAGGGTCTCGGAGAAAACGCAAACCGGCTGAGATTCATCCTG
ATTTTCACCGCGGTGGCGCTGGCGGGAAGCTGTGTAGCCGTCGTCGGCTCAATCGGTTTTATCGGCTTGCTTGCTCCGCA
TATCGCCAGACGGCTTACCGGAGAAAAAGCTAAATATTTACTGCCTGCATCGGCATTGATTGGTGCTATTATATTATTAA
TTGCAGATACGTTAGGGCGCGGCATCATGCCTCCGGTTGAAATACCTGCCGGAATACTGACAGCCGTGATCGGCGCGCCT
TATTTCTTATATTTATTGAAATTCGAAGCGAGGAAACAGTAG

Upstream 100 bases:

>100_bases
GATGGATTGCATTTCCTTATGAATCACCGGTCGGCATTGTCACCGCGATTATCGGAACGCCGTTTTTCTTATATTTGGCA
AGGAAAGGGCGAAACCTGAA

Downstream 100 bases:

>100_bases
GGAGAGGATACCATGGGAAAACTGGCTGCAGACCAGCTCACTCTTTCATATGACAGTACAGTGATTATTGACGGAGTCGA
CTTAAAGATAGAAGAAGGAA

Product: iron-dicitrate ABC transporter permease

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: Ferric-citrate import system permease protein

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MKKTTRKQKRPLLAILILAVILIVLSVISIGIGALYISPDAVVTNLLGLDHSFEFIIQQYRLPRIILAILAGAGLAAAGA
ILQGVIRNPLASPDVVGISKGSGLAAMAVILIFPESPVYVLPFSAFAGAAIIAVLLLMIARKKSIQPSSLALSGIALGAV
CHAGMQYMMVKFPGDVNAALIWLTGSLWGRNWEEVKLLAPWLLILFPIVCILIPKLDLMSLGDELAQGLGENANRLRFIL
IFTAVALAGSCVAVVGSIGFIGLLAPHIARRLTGEKAKYLLPASALIGAIILLIADTLGRGIMPPVEIPAGILTAVIGAP
YFLYLLKFEARKQ

Sequences:

>Translated_333_residues
MKKTTRKQKRPLLAILILAVILIVLSVISIGIGALYISPDAVVTNLLGLDHSFEFIIQQYRLPRIILAILAGAGLAAAGA
ILQGVIRNPLASPDVVGISKGSGLAAMAVILIFPESPVYVLPFSAFAGAAIIAVLLLMIARKKSIQPSSLALSGIALGAV
CHAGMQYMMVKFPGDVNAALIWLTGSLWGRNWEEVKLLAPWLLILFPIVCILIPKLDLMSLGDELAQGLGENANRLRFIL
IFTAVALAGSCVAVVGSIGFIGLLAPHIARRLTGEKAKYLLPASALIGAIILLIADTLGRGIMPPVEIPAGILTAVIGAP
YFLYLLKFEARKQ
>Mature_333_residues
MKKTTRKQKRPLLAILILAVILIVLSVISIGIGALYISPDAVVTNLLGLDHSFEFIIQQYRLPRIILAILAGAGLAAAGA
ILQGVIRNPLASPDVVGISKGSGLAAMAVILIFPESPVYVLPFSAFAGAAIIAVLLLMIARKKSIQPSSLALSGIALGAV
CHAGMQYMMVKFPGDVNAALIWLTGSLWGRNWEEVKLLAPWLLILFPIVCILIPKLDLMSLGDELAQGLGENANRLRFIL
IFTAVALAGSCVAVVGSIGFIGLLAPHIARRLTGEKAKYLLPASALIGAIILLIADTLGRGIMPPVEIPAGILTAVIGAP
YFLYLLKFEARKQ

Specific function: Part of the ABC transporter complex yfmCDEF involved in citrate-dependent Fe(3+) import. Involved in the translocation of the substrate across the membrane (Probable)

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily

Homologues:

Organism=Escherichia coli, GI1790740, Length=301, Percent_Identity=44.5182724252492, Blast_Score=244, Evalue=7e-66,
Organism=Escherichia coli, GI1790741, Length=279, Percent_Identity=37.2759856630824, Blast_Score=149, Evalue=3e-37,
Organism=Escherichia coli, GI1786804, Length=328, Percent_Identity=31.4024390243902, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1786347, Length=275, Percent_Identity=33.8181818181818, Blast_Score=138, Evalue=6e-34,
Organism=Escherichia coli, GI1788004, Length=301, Percent_Identity=35.5481727574751, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI1786805, Length=303, Percent_Identity=33.003300330033, Blast_Score=113, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YFME_BACSU (O34832)

Other databases:

- EMBL:   D86417
- EMBL:   AL009126
- PIR:   D69812
- RefSeq:   NP_388631.1
- HSSP:   P06609
- ProteinModelPortal:   O34832
- SMR:   O34832
- EnsemblBacteria:   EBBACT00000002935
- GeneID:   939692
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU07500
- NMPDR:   fig|224308.1.peg.750
- GenoList:   BSU07500
- GeneTree:   EBGT00070000031905
- HOGENOM:   HBG700016
- OMA:   EINTAMI
- PhylomeDB:   O34832
- ProtClustDB:   CLSK2460894
- BioCyc:   BSUB:BSU07500-MONOMER
- InterPro:   IPR000522

Pfam domain/function: PF01032 FecCD

EC number: NA

Molecular weight: Translated: 35219; Mature: 35219

Theoretical pI: Translated: 10.23; Mature: 10.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xc9eaefc)-; HASH(0xc9cc8f8)-; HASH(0xcc79c00)-; HASH(0xdad871c)-; HASH(0xc5d7e28)-; HASH(0xdb0e05c)-; HASH(0xd8fc3bc)-; HASH(0xc08c49c)-;

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKTTRKQKRPLLAILILAVILIVLSVISIGIGALYISPDAVVTNLLGLDHSFEFIIQQY
CCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHEEECHHHHHHHHHCCCCHHHHHHHHH
RLPRIILAILAGAGLAAAGAILQGVIRNPLASPDVVGISKGSGLAAMAVILIFPESPVYV
CHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHEEECCCCEEE
LPFSAFAGAAIIAVLLLMIARKKSIQPSSLALSGIALGAVCHAGMQYMMVKFPGDVNAAL
EEHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCHHEEEEECCCCCCEEE
IWLTGSLWGRNWEEVKLLAPWLLILFPIVCILIPKLDLMSLGDELAQGLGENANRLRFIL
EEEECCHHCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHH
IFTAVALAGSCVAVVGSIGFIGLLAPHIARRLTGEKAKYLLPASALIGAIILLIADTLGR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHHHHHCC
GIMPPVEIPAGILTAVIGAPYFLYLLKFEARKQ
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCH
>Mature Secondary Structure
MKKTTRKQKRPLLAILILAVILIVLSVISIGIGALYISPDAVVTNLLGLDHSFEFIIQQY
CCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHEEECHHHHHHHHHCCCCHHHHHHHHH
RLPRIILAILAGAGLAAAGAILQGVIRNPLASPDVVGISKGSGLAAMAVILIFPESPVYV
CHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHEEECCCCEEE
LPFSAFAGAAIIAVLLLMIARKKSIQPSSLALSGIALGAVCHAGMQYMMVKFPGDVNAAL
EEHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCHHEEEEECCCCCCEEE
IWLTGSLWGRNWEEVKLLAPWLLILFPIVCILIPKLDLMSLGDELAQGLGENANRLRFIL
EEEECCHHCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHH
IFTAVALAGSCVAVVGSIGFIGLLAPHIARRLTGEKAKYLLPASALIGAIILLIADTLGR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHHHHHCC
GIMPPVEIPAGILTAVIGAPYFLYLLKFEARKQ
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9272861; 9384377