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The map label for this gene is vmlR

Identifier: 16077628

GI number: 16077628

Start: 604736

End: 606379

Strand: Reverse

Name: vmlR

Synonym: BSU05610

Alternate gene names: 16077628

Gene position: 606379-604736 (Counterclockwise)

Preceding gene: 16077629

Following gene: 16077624

Centisome position: 14.38

GC content: 43.98

Gene sequence:

>1644_bases
ATGAAAGAGATCGTAACATTAACAAACGTTAGCTATGAAGTAAAGGATCAAACTGTTTTTAAACATGTAAACGCCAGTGT
TCAGCAAGGAGATATCATTGGGATTATCGGCAAAAACGGCGCTGGGAAATCTACGTTGCTGCACCTCATTCACAATGACT
TAGCCCCTGCACAGGGTCAAATCCTTCGGAAGGATATAAAACTGGCTTTGGTTGAACAGGAAACCGCGGCGTATTCCTTT
GCGGATCAGACACCTGCCGAAAAGAAGTTACTGGAGAAATGGCATGTGCCTCTTCGTGATTTTCATCAGTTAAGCGGCGG
TGAAAAACTGAAAGCGCGGCTGGCGAAAGGACTATCAGAGGATGCAGATCTGCTGCTGTTAGATGAACCGACAAACCACC
TTGATGAAAAAAGCTTGCAATTTCTCATCCAACAGCTGAAACATTATAACGGCACTGTGATTCTCGTTTCTCACGATCGA
TATTTTTTAGACGAAGCCGCAACAAAAATATGGTCGCTTGAGGATCAGACGCTGATTGAATTCAAAGGGAATTACTCCGG
GTATATGAAGTTCCGGGAGAAGAAAAGACTCACCCAGCAGCGTGAATATGAAAAGCAGCAAAAAATGGTTGAACGGATTG
AAGCACAAATGAATGGGCTCGCTTCTTGGTCGGAAAAAGCCCATGCTCAATCGACGAAAAAGGAAGGGTTTAAAGAATAT
CACCGGGTAAAAGCGAAGCGTACGGATGCCCAGATAAAATCCAAGCAGAAGCGGCTTGAAAAAGAGCTTGAAAAAGCAAA
GGCGGAACCCGTTACCCCAGAATATACAGTCCGCTTTTCAATCGATACAACCCACAAAACAGGAAAACGTTTTTTAGAAG
TTCAGAATGTAACAAAAGCGTTTGGAGAAAGGACTCTCTTTAAAAACGCAAACTTTACAATTCAGCACGGCGAAAAGGTT
GCGATCATAGGCCCCAATGGCAGCGGAAAAACGACATTACTGAACATCATTCTGGGACAGGAAACAGCAGAAGGAAGTGT
ATGGGTGTCGCCGTCCGCAAACATCGGCTATTTAACGCAGGAGGTGTTTGATTTGCCTTTAGAACAAACACCGGAAGAGT
TATTTGAGAATGAAACATTCAAAGCAAGGGGGCACGTTCAAAATCTGATGAGGCACTTAGGTTTTACAGCCGCCCAATGG
ACTGAACCGATCAAGCATATGAGTATGGGTGAGCGTGTAAAGATCAAGCTGATGGCATATATTCTGGAGGAAAAAGACGT
GCTGATTTTAGATGAGCCGACAAACCATCTCGACCTGCCGTCACGCGAACAGCTGGAAGAAACACTGTCACAATACAGCG
GCACATTGCTGGCGGTTTCACATGACCGATACTTTCTCGAAAAAACAACAAACAGTAAACTCGTCATCTCAAACAACGGC
ATCGAAAAGCAGTTAAACGACGTTCCTTCAGAAAGAAATGAGCGGGAGGAGCTTCGGTTAAAGCTTGAGACAGAAAGACA
AGAAGTGCTGGGAAAGCTCAGTTTTATGACGCCAAATGATAAAGGGTATAAGGAGCTTGATCAGGCTTTCAATGAGCTTA
CGAAACGAATAAAAGAGCTGGATCATCAAGACAAAAAAGACTGA

Upstream 100 bases:

>100_bases
TTTATAAAAAATAGCTTATTTGATCATGCACAGGCACGGCTAATCCTTCCAACACATTTGGGAGGATTTTTTTATTCTCC
CTTTAAAGCGAGGGATATGG

Downstream 100 bases:

>100_bases
GGGAGAAAGTTCAAGCGGCATTGAAAAGGACAACAGCTGTTGTCCTTTTTCTTTATATGTTCAAGCCTCCCATGACCTTA
ATCTTTCTAATGATGACTTA

Product: ATP-binding cassette efflux transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 547; Mature: 547

Protein sequence:

>547_residues
MKEIVTLTNVSYEVKDQTVFKHVNASVQQGDIIGIIGKNGAGKSTLLHLIHNDLAPAQGQILRKDIKLALVEQETAAYSF
ADQTPAEKKLLEKWHVPLRDFHQLSGGEKLKARLAKGLSEDADLLLLDEPTNHLDEKSLQFLIQQLKHYNGTVILVSHDR
YFLDEAATKIWSLEDQTLIEFKGNYSGYMKFREKKRLTQQREYEKQQKMVERIEAQMNGLASWSEKAHAQSTKKEGFKEY
HRVKAKRTDAQIKSKQKRLEKELEKAKAEPVTPEYTVRFSIDTTHKTGKRFLEVQNVTKAFGERTLFKNANFTIQHGEKV
AIIGPNGSGKTTLLNIILGQETAEGSVWVSPSANIGYLTQEVFDLPLEQTPEELFENETFKARGHVQNLMRHLGFTAAQW
TEPIKHMSMGERVKIKLMAYILEEKDVLILDEPTNHLDLPSREQLEETLSQYSGTLLAVSHDRYFLEKTTNSKLVISNNG
IEKQLNDVPSERNEREELRLKLETERQEVLGKLSFMTPNDKGYKELDQAFNELTKRIKELDHQDKKD

Sequences:

>Translated_547_residues
MKEIVTLTNVSYEVKDQTVFKHVNASVQQGDIIGIIGKNGAGKSTLLHLIHNDLAPAQGQILRKDIKLALVEQETAAYSF
ADQTPAEKKLLEKWHVPLRDFHQLSGGEKLKARLAKGLSEDADLLLLDEPTNHLDEKSLQFLIQQLKHYNGTVILVSHDR
YFLDEAATKIWSLEDQTLIEFKGNYSGYMKFREKKRLTQQREYEKQQKMVERIEAQMNGLASWSEKAHAQSTKKEGFKEY
HRVKAKRTDAQIKSKQKRLEKELEKAKAEPVTPEYTVRFSIDTTHKTGKRFLEVQNVTKAFGERTLFKNANFTIQHGEKV
AIIGPNGSGKTTLLNIILGQETAEGSVWVSPSANIGYLTQEVFDLPLEQTPEELFENETFKARGHVQNLMRHLGFTAAQW
TEPIKHMSMGERVKIKLMAYILEEKDVLILDEPTNHLDLPSREQLEETLSQYSGTLLAVSHDRYFLEKTTNSKLVISNNG
IEKQLNDVPSERNEREELRLKLETERQEVLGKLSFMTPNDKGYKELDQAFNELTKRIKELDHQDKKD
>Mature_547_residues
MKEIVTLTNVSYEVKDQTVFKHVNASVQQGDIIGIIGKNGAGKSTLLHLIHNDLAPAQGQILRKDIKLALVEQETAAYSF
ADQTPAEKKLLEKWHVPLRDFHQLSGGEKLKARLAKGLSEDADLLLLDEPTNHLDEKSLQFLIQQLKHYNGTVILVSHDR
YFLDEAATKIWSLEDQTLIEFKGNYSGYMKFREKKRLTQQREYEKQQKMVERIEAQMNGLASWSEKAHAQSTKKEGFKEY
HRVKAKRTDAQIKSKQKRLEKELEKAKAEPVTPEYTVRFSIDTTHKTGKRFLEVQNVTKAFGERTLFKNANFTIQHGEKV
AIIGPNGSGKTTLLNIILGQETAEGSVWVSPSANIGYLTQEVFDLPLEQTPEELFENETFKARGHVQNLMRHLGFTAAQW
TEPIKHMSMGERVKIKLMAYILEEKDVLILDEPTNHLDLPSREQLEETLSQYSGTLLAVSHDRYFLEKTTNSKLVISNNG
IEKQLNDVPSERNEREELRLKLETERQEVLGKLSFMTPNDKGYKELDQAFNELTKRIKELDHQDKKD

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains

Homologues:

Organism=Homo sapiens, GI10947135, Length=532, Percent_Identity=28.7593984962406, Blast_Score=175, Evalue=8e-44,
Organism=Homo sapiens, GI69354671, Length=532, Percent_Identity=28.7593984962406, Blast_Score=175, Evalue=9e-44,
Organism=Homo sapiens, GI148612853, Length=540, Percent_Identity=26.6666666666667, Blast_Score=168, Evalue=1e-41,
Organism=Homo sapiens, GI10947137, Length=539, Percent_Identity=25.2319109461967, Blast_Score=154, Evalue=3e-37,
Organism=Homo sapiens, GI27881506, Length=539, Percent_Identity=25.2319109461967, Blast_Score=154, Evalue=3e-37,
Organism=Escherichia coli, GI1789751, Length=560, Percent_Identity=28.75, Blast_Score=219, Evalue=5e-58,
Organism=Escherichia coli, GI1787041, Length=543, Percent_Identity=29.8342541436464, Blast_Score=191, Evalue=7e-50,
Organism=Escherichia coli, GI1787182, Length=542, Percent_Identity=27.6752767527675, Blast_Score=185, Evalue=8e-48,
Organism=Escherichia coli, GI2367384, Length=529, Percent_Identity=28.1663516068053, Blast_Score=177, Evalue=1e-45,
Organism=Escherichia coli, GI87081782, Length=503, Percent_Identity=22.2664015904573, Blast_Score=92, Evalue=8e-20,
Organism=Escherichia coli, GI1788165, Length=197, Percent_Identity=25.8883248730964, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI87081709, Length=217, Percent_Identity=26.7281105990783, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788053, Length=178, Percent_Identity=29.7752808988764, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1787712, Length=212, Percent_Identity=27.3584905660377, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1786253, Length=204, Percent_Identity=26.9607843137255, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI48995001, Length=214, Percent_Identity=26.6355140186916, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI1788225, Length=223, Percent_Identity=23.7668161434978, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI1788540, Length=193, Percent_Identity=27.979274611399, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1786698, Length=192, Percent_Identity=27.0833333333333, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1787029, Length=233, Percent_Identity=24.8927038626609, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI87082267, Length=232, Percent_Identity=25.8620689655172, Blast_Score=63, Evalue=6e-11,
Organism=Escherichia coli, GI1786563, Length=218, Percent_Identity=25.2293577981651, Blast_Score=62, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17559834, Length=546, Percent_Identity=27.4725274725275, Blast_Score=183, Evalue=2e-46,
Organism=Caenorhabditis elegans, GI17555318, Length=521, Percent_Identity=25.9117082533589, Blast_Score=170, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI17553372, Length=403, Percent_Identity=30.0248138957816, Blast_Score=152, Evalue=6e-37,
Organism=Saccharomyces cerevisiae, GI6321121, Length=367, Percent_Identity=32.9700272479564, Blast_Score=172, Evalue=2e-43,
Organism=Saccharomyces cerevisiae, GI6320874, Length=390, Percent_Identity=29.2307692307692, Blast_Score=167, Evalue=4e-42,
Organism=Saccharomyces cerevisiae, GI6324314, Length=372, Percent_Identity=27.6881720430108, Blast_Score=109, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6325030, Length=377, Percent_Identity=26.790450928382, Blast_Score=99, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6323278, Length=171, Percent_Identity=33.3333333333333, Blast_Score=87, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24641342, Length=403, Percent_Identity=32.7543424317618, Blast_Score=179, Evalue=3e-45,
Organism=Drosophila melanogaster, GI24666836, Length=535, Percent_Identity=28.2242990654206, Blast_Score=178, Evalue=9e-45,
Organism=Drosophila melanogaster, GI24642252, Length=510, Percent_Identity=25.2941176470588, Blast_Score=155, Evalue=6e-38,
Organism=Drosophila melanogaster, GI18859989, Length=510, Percent_Identity=25.2941176470588, Blast_Score=155, Evalue=6e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): EXPZ_BACSU (P39115)

Other databases:

- EMBL:   AB001488
- EMBL:   AL009126
- EMBL:   X79387
- PIR:   G69620
- RefSeq:   NP_388442.1
- ProteinModelPortal:   P39115
- EnsemblBacteria:   EBBACT00000002645
- GeneID:   938053
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU05610
- NMPDR:   fig|224308.1.peg.561
- GenoList:   BSU05610
- GeneTree:   EBGT00070000032002
- HOGENOM:   HBG758042
- OMA:   MAYILAD
- ProtClustDB:   CLSK886784
- BioCyc:   BSUB:BSU05610-MONOMER
- InterPro:   IPR003439
- InterPro:   IPR003593
- SMART:   SM00382

Pfam domain/function: PF00005 ABC_tran

EC number: NA

Molecular weight: Translated: 62739; Mature: 62739

Theoretical pI: Translated: 7.20; Mature: 7.20

Prosite motif: PS00211 ABC_TRANSPORTER_1; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEIVTLTNVSYEVKDQTVFKHVNASVQQGDIIGIIGKNGAGKSTLLHLIHNDLAPAQGQ
CCCEEEEECCEEEECHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCCCHHH
ILRKDIKLALVEQETAAYSFADQTPAEKKLLEKWHVPLRDFHQLSGGEKLKARLAKGLSE
HHHHHHHEEEEEHHHHHHCCCCCCCHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHCCCCC
DADLLLLDEPTNHLDEKSLQFLIQQLKHYNGTVILVSHDRYFLDEAATKIWSLEDQTLIE
CCCEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHCCCCCEEEE
FKGNYSGYMKFREKKRLTQQREYEKQQKMVERIEAQMNGLASWSEKAHAQSTKKEGFKEY
ECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HRVKAKRTDAQIKSKQKRLEKELEKAKAEPVTPEYTVRFSIDTTHKTGKRFLEVQNVTKA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCHHHHHHHHHHHHHHHH
FGERTLFKNANFTIQHGEKVAIIGPNGSGKTTLLNIILGQETAEGSVWVSPSANIGYLTQ
HCCHHEECCCCEEEECCCEEEEECCCCCCCEEEEEEEECCCCCCCCEEECCCCCCCHHHH
EVFDLPLEQTPEELFENETFKARGHVQNLMRHLGFTAAQWTEPIKHMSMGERVKIKLMAY
HHHHCCCCCCHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHH
ILEEKDVLILDEPTNHLDLPSREQLEETLSQYSGTLLAVSHDRYFLEKTTNSKLVISNNG
HHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHCCEEEEEECCCEEEEECCCCEEEEECCC
IEKQLNDVPSERNEREELRLKLETERQEVLGKLSFMTPNDKGYKELDQAFNELTKRIKEL
CHHHHHCCCCCCCCHHHHHEEEHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
DHQDKKD
CCCCCCC
>Mature Secondary Structure
MKEIVTLTNVSYEVKDQTVFKHVNASVQQGDIIGIIGKNGAGKSTLLHLIHNDLAPAQGQ
CCCEEEEECCEEEECHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCCCHHH
ILRKDIKLALVEQETAAYSFADQTPAEKKLLEKWHVPLRDFHQLSGGEKLKARLAKGLSE
HHHHHHHEEEEEHHHHHHCCCCCCCHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHCCCCC
DADLLLLDEPTNHLDEKSLQFLIQQLKHYNGTVILVSHDRYFLDEAATKIWSLEDQTLIE
CCCEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHCCCCCEEEE
FKGNYSGYMKFREKKRLTQQREYEKQQKMVERIEAQMNGLASWSEKAHAQSTKKEGFKEY
ECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HRVKAKRTDAQIKSKQKRLEKELEKAKAEPVTPEYTVRFSIDTTHKTGKRFLEVQNVTKA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCHHHHHHHHHHHHHHHH
FGERTLFKNANFTIQHGEKVAIIGPNGSGKTTLLNIILGQETAEGSVWVSPSANIGYLTQ
HCCHHEECCCCEEEECCCEEEEECCCCCCCEEEEEEEECCCCCCCCEEECCCCCCCHHHH
EVFDLPLEQTPEELFENETFKARGHVQNLMRHLGFTAAQWTEPIKHMSMGERVKIKLMAY
HHHHCCCCCCHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHH
ILEEKDVLILDEPTNHLDLPSREQLEETLSQYSGTLLAVSHDRYFLEKTTNSKLVISNNG
HHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHCCEEEEEECCCEEEEECCCCEEEEECCC
IEKQLNDVPSERNEREELRLKLETERQEVLGKLSFMTPNDKGYKELDQAFNELTKRIKEL
CHHHHHCCCCCCCCHHHHHEEEHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
DHQDKKD
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377