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The map label for this gene is ydgF

Identifier: 16077629

GI number: 16077629

Start: 606699

End: 608075

Strand: Reverse

Name: ydgF

Synonym: BSU05620

Alternate gene names: 16077629

Gene position: 608075-606699 (Counterclockwise)

Preceding gene: 16077630

Following gene: 16077628

Centisome position: 14.42

GC content: 44.3

Gene sequence:

>1377_bases
GTGACAGACGACATGACGAAAGACAATATAAATCAGCAAACGTTGCAGAGAGGCTTGAAAAACAGGCATATCCAGCTCAT
CGCCATCGGCGGAGCCATTGGGACAGGCTTATTTCTCGGCTCGGGCAAATCGATTCATTTTGCCGGACCTTCGATTTTAT
TTGCTTATATGATCACAGGGATCATTTGCTTTTTAATTATGAGATCGCTGGGTGAACTGCTGTTATCAAACTTGAACTAT
CACTCTTTTGTGGATTTTGTACAAGACTACCTAGGCGATATGGCAGCTTTTATCACCGGCTGGACATATTGGTTCTGCTG
GATTTCCATTGCGATGGCTGATCTGACAGCAGTCGGGCTCTACACTCAATATTGGCTCCCGGGTGTGCCGCAATGGGTGC
CTGGCTTAATCGCTCTTATTATTTTACTGATTATGAATCTGGCGACAGTCAAGCTTTTTGGAGAATTAGAATTTTGGTTC
GCTTTGATTAAAGTCATTGCCATTTTGGCGTTAATCGTCATTGGCCTTGTGATGATTTTCAAAGGCTTTTCCACAAGCTC
AGGAGTGTCCAGCTTCACAAACCTCTGGAGCCACGGAGGCCTGTTCCCGAATGGCATGCACGGGTTTATCCTCTCGTTCC
AGATGGTTGTGTTTGCTTTTGTCGGCATTGAGCTTGTCGGGCTTACGGCCGGTGAAACAGAAAACCCTGAAAAAGTAATC
CCTAAGGCGATCAACAATATTCCTGTCCGTGTGCTGCTTTTTTATATCGGGGCTCTTCTCGTGATTATGAGCATCTATCC
TTGGGATATCATCAATCCCAGCGAAAGCCCATTCGTACAAGTATTTGTCGCTGTTGGCATCGTCGGGGCTGCAAGTATTA
TCAACTTTGTTGTGTTGACATCCGCTGCTTCAGCATGCAACAGCGCTGTATTCAGTACAAGCCGTATGGTCTATTCCCTG
GCGAAAGATCACAATGCGCCTGAGTCAATGGCGAAACTGACTCAGCGTAAAGTGCCTAGAAATGCTTTATTCTTTTCAGC
TATCGTGATTTTAATCGGTGTTACGTTAAACTACATCATGCCAGAAGGCGTATTCACCCTGATCACAAGTATTTCAACCG
TATGCTTTATCTACATTTGGGGGATTACGGTCATCTGCCATATGAAATACCGCAAAACAAGACCTGAATTAGCGAAAACA
AACAAGTTTAAGCTTCCGCTTTATCCGTTTACAAATTACCTGATTCTTGCGTTCCTGGCGTTTGTTCTGGTTGTGCTGGC
ACTGGCACAGGATACTCGTGTTTCCTTATTTGTCACACCGGTTTGGTTTATTTTGCTGATTGTGATTTATAAAGTGAGAA
AAGCGAAGCATCAATAA

Upstream 100 bases:

>100_bases
ATCCTTTTTTAGTAAAAAAGATAGAAATTTTAGTGTTATAATAATCATTAAAAATAGATTGCTGACTCAATAAACAATTT
TCAATGGAGGAACACATAAA

Downstream 100 bases:

>100_bases
GACTCAAAACTCCTGCCTCAAAAATGAGAGCAGGAGTTTTTTTGATGAAAATGACCTTTGCTTTTGAATTTAAAGGTATG
CTATAGTGTTTGTAATCAAA

Product: amino acid permease

Products: D-glycine [Cytoplasm]; D-alanine [Cytoplasm]; Proton [Cytoplasm]; D-serine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 458; Mature: 457

Protein sequence:

>458_residues
MTDDMTKDNINQQTLQRGLKNRHIQLIAIGGAIGTGLFLGSGKSIHFAGPSILFAYMITGIICFLIMRSLGELLLSNLNY
HSFVDFVQDYLGDMAAFITGWTYWFCWISIAMADLTAVGLYTQYWLPGVPQWVPGLIALIILLIMNLATVKLFGELEFWF
ALIKVIAILALIVIGLVMIFKGFSTSSGVSSFTNLWSHGGLFPNGMHGFILSFQMVVFAFVGIELVGLTAGETENPEKVI
PKAINNIPVRVLLFYIGALLVIMSIYPWDIINPSESPFVQVFVAVGIVGAASIINFVVLTSAASACNSAVFSTSRMVYSL
AKDHNAPESMAKLTQRKVPRNALFFSAIVILIGVTLNYIMPEGVFTLITSISTVCFIYIWGITVICHMKYRKTRPELAKT
NKFKLPLYPFTNYLILAFLAFVLVVLALAQDTRVSLFVTPVWFILLIVIYKVRKAKHQ

Sequences:

>Translated_458_residues
MTDDMTKDNINQQTLQRGLKNRHIQLIAIGGAIGTGLFLGSGKSIHFAGPSILFAYMITGIICFLIMRSLGELLLSNLNY
HSFVDFVQDYLGDMAAFITGWTYWFCWISIAMADLTAVGLYTQYWLPGVPQWVPGLIALIILLIMNLATVKLFGELEFWF
ALIKVIAILALIVIGLVMIFKGFSTSSGVSSFTNLWSHGGLFPNGMHGFILSFQMVVFAFVGIELVGLTAGETENPEKVI
PKAINNIPVRVLLFYIGALLVIMSIYPWDIINPSESPFVQVFVAVGIVGAASIINFVVLTSAASACNSAVFSTSRMVYSL
AKDHNAPESMAKLTQRKVPRNALFFSAIVILIGVTLNYIMPEGVFTLITSISTVCFIYIWGITVICHMKYRKTRPELAKT
NKFKLPLYPFTNYLILAFLAFVLVVLALAQDTRVSLFVTPVWFILLIVIYKVRKAKHQ
>Mature_457_residues
TDDMTKDNINQQTLQRGLKNRHIQLIAIGGAIGTGLFLGSGKSIHFAGPSILFAYMITGIICFLIMRSLGELLLSNLNYH
SFVDFVQDYLGDMAAFITGWTYWFCWISIAMADLTAVGLYTQYWLPGVPQWVPGLIALIILLIMNLATVKLFGELEFWFA
LIKVIAILALIVIGLVMIFKGFSTSSGVSSFTNLWSHGGLFPNGMHGFILSFQMVVFAFVGIELVGLTAGETENPEKVIP
KAINNIPVRVLLFYIGALLVIMSIYPWDIINPSESPFVQVFVAVGIVGAASIINFVVLTSAASACNSAVFSTSRMVYSLA
KDHNAPESMAKLTQRKVPRNALFFSAIVILIGVTLNYIMPEGVFTLITSISTVCFIYIWGITVICHMKYRKTRPELAKTN
KFKLPLYPFTNYLILAFLAFVLVVLALAQDTRVSLFVTPVWFILLIVIYKVRKAKHQ

Specific function: Probable amino-acid or metabolite transport protein

COG id: COG1113

COG function: function code E; Gamma-aminobutyrate permease and related permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily

Homologues:

Organism=Homo sapiens, GI115648063, Length=431, Percent_Identity=23.2018561484919, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI115648022, Length=431, Percent_Identity=23.2018561484919, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI110347453, Length=342, Percent_Identity=23.3918128654971, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI4507047, Length=363, Percent_Identity=23.9669421487603, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI181337167, Length=327, Percent_Identity=22.9357798165138, Blast_Score=67, Evalue=4e-11,
Organism=Escherichia coli, GI1790653, Length=452, Percent_Identity=54.4247787610619, Blast_Score=511, Evalue=1e-146,
Organism=Escherichia coli, GI1786789, Length=457, Percent_Identity=42.4507658643326, Blast_Score=399, Evalue=1e-112,
Organism=Escherichia coli, GI1786302, Length=454, Percent_Identity=42.7312775330396, Blast_Score=397, Evalue=1e-112,
Organism=Escherichia coli, GI48994972, Length=444, Percent_Identity=43.018018018018, Blast_Score=385, Evalue=1e-108,
Organism=Escherichia coli, GI1786602, Length=450, Percent_Identity=44.2222222222222, Blast_Score=366, Evalue=1e-102,
Organism=Escherichia coli, GI87081915, Length=408, Percent_Identity=40.6862745098039, Blast_Score=335, Evalue=3e-93,
Organism=Escherichia coli, GI1789017, Length=417, Percent_Identity=33.3333333333333, Blast_Score=261, Evalue=9e-71,
Organism=Escherichia coli, GI87081708, Length=441, Percent_Identity=34.0136054421769, Blast_Score=255, Evalue=4e-69,
Organism=Escherichia coli, GI1788480, Length=391, Percent_Identity=37.0843989769821, Blast_Score=249, Evalue=2e-67,
Organism=Escherichia coli, GI87081869, Length=314, Percent_Identity=23.5668789808917, Blast_Score=63, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17540018, Length=430, Percent_Identity=24.1860465116279, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6320772, Length=448, Percent_Identity=32.8125, Blast_Score=201, Evalue=2e-52,
Organism=Saccharomyces cerevisiae, GI6324061, Length=486, Percent_Identity=30.4526748971193, Blast_Score=198, Evalue=2e-51,
Organism=Saccharomyces cerevisiae, GI6324924, Length=406, Percent_Identity=31.2807881773399, Blast_Score=187, Evalue=2e-48,
Organism=Saccharomyces cerevisiae, GI6322892, Length=441, Percent_Identity=29.2517006802721, Blast_Score=175, Evalue=1e-44,
Organism=Saccharomyces cerevisiae, GI6324990, Length=369, Percent_Identity=33.3333333333333, Blast_Score=168, Evalue=1e-42,
Organism=Saccharomyces cerevisiae, GI6321053, Length=437, Percent_Identity=28.1464530892449, Blast_Score=167, Evalue=3e-42,
Organism=Saccharomyces cerevisiae, GI6324059, Length=456, Percent_Identity=31.140350877193, Blast_Score=162, Evalue=2e-40,
Organism=Saccharomyces cerevisiae, GI6321629, Length=426, Percent_Identity=26.5258215962441, Blast_Score=151, Evalue=2e-37,
Organism=Saccharomyces cerevisiae, GI6320717, Length=400, Percent_Identity=25.75, Blast_Score=149, Evalue=7e-37,
Organism=Saccharomyces cerevisiae, GI6319824, Length=418, Percent_Identity=25.5980861244019, Blast_Score=147, Evalue=5e-36,
Organism=Saccharomyces cerevisiae, GI6319608, Length=346, Percent_Identity=28.0346820809249, Blast_Score=140, Evalue=4e-34,
Organism=Saccharomyces cerevisiae, GI6319543, Length=410, Percent_Identity=25.609756097561, Blast_Score=139, Evalue=7e-34,
Organism=Saccharomyces cerevisiae, GI6324553, Length=401, Percent_Identity=27.1820448877805, Blast_Score=136, Evalue=7e-33,
Organism=Saccharomyces cerevisiae, GI6320251, Length=412, Percent_Identity=25.4854368932039, Blast_Score=135, Evalue=1e-32,
Organism=Saccharomyces cerevisiae, GI6319542, Length=412, Percent_Identity=24.5145631067961, Blast_Score=131, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6322967, Length=397, Percent_Identity=26.448362720403, Blast_Score=124, Evalue=3e-29,
Organism=Saccharomyces cerevisiae, GI6324981, Length=405, Percent_Identity=27.1604938271605, Blast_Score=117, Evalue=5e-27,
Organism=Saccharomyces cerevisiae, GI6320364, Length=486, Percent_Identity=25.1028806584362, Blast_Score=97, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24667468, Length=337, Percent_Identity=23.4421364985163, Blast_Score=65, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YDGF_BACSU (P96704)

Other databases:

- EMBL:   AB001488
- EMBL:   AL009126
- PIR:   H69782
- RefSeq:   NP_388443.1
- ProteinModelPortal:   P96704
- EnsemblBacteria:   EBBACT00000001482
- GeneID:   938050
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU05620
- NMPDR:   fig|224308.1.peg.562
- GenoList:   BSU05620
- GeneTree:   EBGT00070000031860
- HOGENOM:   HBG492579
- OMA:   TAVGLYT
- PhylomeDB:   P96704
- ProtClustDB:   CLSK882815
- BioCyc:   BSUB:BSU05620-MONOMER
- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004840
- PANTHER:   PTHR11785
- PIRSF:   PIRSF006060

Pfam domain/function: PF00324 AA_permease

EC number: NA

Molecular weight: Translated: 50790; Mature: 50659

Theoretical pI: Translated: 9.46; Mature: 9.46

Prosite motif: PS00218 AMINO_ACID_PERMEASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xd45b688)-; HASH(0xd29c9a4)-; HASH(0xbae98e8)-; HASH(0xc6c3f44)-; HASH(0xaf74c48)-; HASH(0xc79091c)-; HASH(0xc37519c)-; HASH(0xbf131b8)-; HASH(0xc332d8c)-; HASH(0xc2b01f4)-; HASH(0xcf5bb78)-; HASH(0xbe7c5e8)-;

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDDMTKDNINQQTLQRGLKNRHIQLIAIGGAIGTGLFLGSGKSIHFAGPSILFAYMITG
CCCCCCCCCCCHHHHHHHHCCCCEEEEEECCHHHHHHEECCCCEEEECCHHHHHHHHHHH
IICFLIMRSLGELLLSNLNYHSFVDFVQDYLGDMAAFITGWTYWFCWISIAMADLTAVGL
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YTQYWLPGVPQWVPGLIALIILLIMNLATVKLFGELEFWFALIKVIAILALIVIGLVMIF
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KGFSTSSGVSSFTNLWSHGGLFPNGMHGFILSFQMVVFAFVGIELVGLTAGETENPEKVI
CCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHHHH
PKAINNIPVRVLLFYIGALLVIMSIYPWDIINPSESPFVQVFVAVGIVGAASIINFVVLT
HHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
SAASACNSAVFSTSRMVYSLAKDHNAPESMAKLTQRKVPRNALFFSAIVILIGVTLNYIM
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHC
PEGVFTLITSISTVCFIYIWGITVICHMKYRKTRPELAKTNKFKLPLYPFTNYLILAFLA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCHHHHHHHHHHH
FVLVVLALAQDTRVSLFVTPVWFILLIVIYKVRKAKHQ
HHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHCCH
>Mature Secondary Structure 
TDDMTKDNINQQTLQRGLKNRHIQLIAIGGAIGTGLFLGSGKSIHFAGPSILFAYMITG
CCCCCCCCCCHHHHHHHHCCCCEEEEEECCHHHHHHEECCCCEEEECCHHHHHHHHHHH
IICFLIMRSLGELLLSNLNYHSFVDFVQDYLGDMAAFITGWTYWFCWISIAMADLTAVGL
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YTQYWLPGVPQWVPGLIALIILLIMNLATVKLFGELEFWFALIKVIAILALIVIGLVMIF
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KGFSTSSGVSSFTNLWSHGGLFPNGMHGFILSFQMVVFAFVGIELVGLTAGETENPEKVI
CCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHHHH
PKAINNIPVRVLLFYIGALLVIMSIYPWDIINPSESPFVQVFVAVGIVGAASIINFVVLT
HHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
SAASACNSAVFSTSRMVYSLAKDHNAPESMAKLTQRKVPRNALFFSAIVILIGVTLNYIM
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHC
PEGVFTLITSISTVCFIYIWGITVICHMKYRKTRPELAKTNKFKLPLYPFTNYLILAFLA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCHHHHHHHHHHH
FVLVVLALAQDTRVSLFVTPVWFILLIVIYKVRKAKHQ
HHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: D-glycine [Periplasm]; D-alanine [Periplasm]; Proton [Periplasm]; D-serine [Periplasm] [C]

Specific reaction: Proton [Periplasm] + D-glycine [Periplasm] = Proton [Cytoplasm] + D-glycine [Cytoplasm] Proton [Periplasm] + D-alanine [Periplasm] = Proton [Cytoplasm] + D-alanine [Cytoplasm] Proton [Periplasm] + D-serine [Periplasm] = Proton [Cytoplasm] + D-serine [Cyto

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377