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The map label for this gene is dgk

Identifier: 16077083

GI number: 16077083

Start: 23146

End: 23769

Strand: Reverse

Name: dgk

Synonym: BSU00150

Alternate gene names: 16077083

Gene position: 23769-23146 (Counterclockwise)

Preceding gene: 16077084

Following gene: 16077082

Centisome position: 0.56

GC content: 40.54

Gene sequence:

>624_bases
ATGAATACAGCCCCTTTTATTGCAATAGAAGGTCCTATCGGGGCAGGAAAAACAACTCTCGCAACGATGCTCTCACAAAA
ATTCGGATTCCCTATGATCAATGAGATTGTAGAGGATAACCCGTACCTTGATAAGTTTTATGACAATATAAAGGAATGGA
GCTTCCAGCTCGAGATGTTTTTTCTTTGTCACAGATACAAACAGCTTGAAGACACCAGTGATCACTTTTTAAAAAAGGGA
CAGCCTGTAATAGCTGATTATCATATTTATAAAAATGTGATTTTTGCGGAACGAACCTTGTCTCCACATCAGCTGGAAAA
ATACAAAAAGATATATCACCTGCTAACGGATGATCTGCCAAAGCCGAATTTCATCATTTACATAAAGGCCAGTCTGCCTA
CATTGCTACACCGCATTGAAAAACGCGGGCGCCCCTTTGAGAAAAAAATTGAAACTAGCTATTTGGAGCAGCTGATTTCA
GATTATGAAGTCGCCATCAAGCAGCTGCAGGAAGCAGACCCTGAACTTACAGTGTTAACCGTAGATGGTGATTCAAAGGA
TTTCGTTTTGAATAAGAGCGACTTTGAACGCATTGCCGCCCATGTAAAGGAGCTTATCGTATGA

Upstream 100 bases:

>100_bases
AATTTGGAAACGTCTTTTTTTCATGGGGGCACCCAAGGGTTGTGATACAATATGAAGGTCGGTAACTGACGCACGTTTTT
CAGATATAAGGAGGATTCCG

Downstream 100 bases:

>100_bases
AGGAACATCATATCCCTAAGAATTCAATTATTACAGTAGCAGGAACAGTAGGTGTCGGAAAATCGACTTTAACAAAAACT
TTAGCTAAACGGCTTGGATT

Product: deoxyguanosine kinase

Products: NA

Alternate protein names: DGUO kinase; dGK

Number of amino acids: Translated: 207; Mature: 207

Protein sequence:

>207_residues
MNTAPFIAIEGPIGAGKTTLATMLSQKFGFPMINEIVEDNPYLDKFYDNIKEWSFQLEMFFLCHRYKQLEDTSDHFLKKG
QPVIADYHIYKNVIFAERTLSPHQLEKYKKIYHLLTDDLPKPNFIIYIKASLPTLLHRIEKRGRPFEKKIETSYLEQLIS
DYEVAIKQLQEADPELTVLTVDGDSKDFVLNKSDFERIAAHVKELIV

Sequences:

>Translated_207_residues
MNTAPFIAIEGPIGAGKTTLATMLSQKFGFPMINEIVEDNPYLDKFYDNIKEWSFQLEMFFLCHRYKQLEDTSDHFLKKG
QPVIADYHIYKNVIFAERTLSPHQLEKYKKIYHLLTDDLPKPNFIIYIKASLPTLLHRIEKRGRPFEKKIETSYLEQLIS
DYEVAIKQLQEADPELTVLTVDGDSKDFVLNKSDFERIAAHVKELIV
>Mature_207_residues
MNTAPFIAIEGPIGAGKTTLATMLSQKFGFPMINEIVEDNPYLDKFYDNIKEWSFQLEMFFLCHRYKQLEDTSDHFLKKG
QPVIADYHIYKNVIFAERTLSPHQLEKYKKIYHLLTDDLPKPNFIIYIKASLPTLLHRIEKRGRPFEKKIETSYLEQLIS
DYEVAIKQLQEADPELTVLTVDGDSKDFVLNKSDFERIAAHVKELIV

Specific function: Plays an essential role in generating the deoxyribonucleotide precursors dGTP for DNA metabolism. Highly specific toward deoxyguanosine (dGuo) and deoxyinosine (dIno). Only marginal activity is observed with guanosine. UTP is slightly more efficient as ph

COG id: COG1428

COG function: function code F; Deoxynucleoside kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DCK/DGK family

Homologues:

Organism=Homo sapiens, GI4758768, Length=183, Percent_Identity=26.2295081967213, Blast_Score=72, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DGK_BACSU (P37530)

Other databases:

- EMBL:   D26185
- EMBL:   AL009126
- PIR:   S66045
- RefSeq:   NP_387896.1
- ProteinModelPortal:   P37530
- SMR:   P37530
- EnsemblBacteria:   EBBACT00000003729
- GeneID:   937037
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU00150
- NMPDR:   fig|224308.1.peg.15
- GenoList:   BSU00150
- GeneTree:   EBGT00050000000907
- HOGENOM:   HBG725501
- OMA:   DYHIYKN
- ProtClustDB:   CLSK2460881
- BioCyc:   BSUB:BSU00150-MONOMER
- InterPro:   IPR002624
- PANTHER:   PTHR10513

Pfam domain/function: PF01712 dNK

EC number: =2.7.1.113

Molecular weight: Translated: 24145; Mature: 24145

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: NA

Important sites: ACT_SITE 86-86 BINDING 35-35 BINDING 47-47 BINDING 147-147

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTAPFIAIEGPIGAGKTTLATMLSQKFGFPMINEIVEDNPYLDKFYDNIKEWSFQLEMF
CCCCCEEEEECCCCCCHHHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
FLCHRYKQLEDTSDHFLKKGQPVIADYHIYKNVIFAERTLSPHQLEKYKKIYHLLTDDLP
HHHHHHHHHCCCHHHHHHCCCCEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCC
KPNFIIYIKASLPTLLHRIEKRGRPFEKKIETSYLEQLISDYEVAIKQLQEADPELTVLT
CCCEEEEEECHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
VDGDSKDFVLNKSDFERIAAHVKELIV
ECCCCCCEEECHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNTAPFIAIEGPIGAGKTTLATMLSQKFGFPMINEIVEDNPYLDKFYDNIKEWSFQLEMF
CCCCCEEEEECCCCCCHHHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
FLCHRYKQLEDTSDHFLKKGQPVIADYHIYKNVIFAERTLSPHQLEKYKKIYHLLTDDLP
HHHHHHHHHCCCHHHHHHCCCCEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCC
KPNFIIYIKASLPTLLHRIEKRGRPFEKKIETSYLEQLISDYEVAIKQLQEADPELTVLT
CCCEEEEEECHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
VDGDSKDFVLNKSDFERIAAHVKELIV
ECCCCCCEEECHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377