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The map label for this gene is aroB

Identifier: 15618944

GI number: 15618944

Start: 1189981

End: 1191135

Strand: Reverse

Name: aroB

Synonym: CPn1036

Alternate gene names: 15618944

Gene position: 1191135-1189981 (Counterclockwise)

Preceding gene: 15618945

Following gene: 15618943

Centisome position: 96.82

GC content: 40.09

Gene sequence:

>1155_bases
ATGCTCCAAACTATGATGTCAGAGACAATAATTACGACTCCCCATGTAGTGAAACTCATATCCAACTTCTTCCAGAAGAA
GTTGTTCTCTTCTATATCCACAGCGTATCCCTTAGTCATTATTACAGACGTTTCAGTACAACAGCATCTCCTAGGTCCTA
TCTTAGACCATATTAAAATGTTAGGATATCAAGTCATTGTCCTAACCTTTCCTCCTGGAGAACCTAACAAAACCTGGGAA
ACATTCATATCTCTACAATATCAGCTTGTAGATCAGAATATCTCTCCGAAATCTTCAATTATTGGAATTGGAGGGGGGAC
TGTTTTAGATATGACAGGATTTTTAGCTGCTACATATTGTCGAGGGCTCCCTCTATATCTAATTCCCACGACGATCACCG
CAATGGTAGATACGAGTATCGGGGGGAAAAATGGAATCAACTTACGAGGAATCAAAAATCGACTGGGGACATTCTACTTA
CCCAAGGAAGTATGGATGTGTCCTCAGTTCCTCTCTACACTCCCAAGAGAAGAATGGTATCATGGAATTGCAGAAGCAAT
AAAACATGGATTCATCGCGGATGCTTATCTCTGGGAATTTCTAAATAGCCATAGTAAAATGCTATTTTCTTCATCGCAGA
TCCTCCACGAGTTCATCAAAAGAAACTGCCAAATCAAAGCGGCGATTGTCGCTGAAGATCCCTATGACCGAAGTCTGAGA
AAAATCCTAAACTTCGGTCACTCCATAGCCCACGCTATAGAAACCCTGGCAAAAGGAACGGTAAATCATGGCCAAGCCGT
AAGTGTCGGTATGATGATAGAAACAAGAATATCTCTTGCTGAAGGAGTTATGAAAACCCCACAACTCATAGACCAACTTG
AAAGACTCCTAAAACGATTTAATCTCCCTTCTACTTTGAAAGATTTACAATCTATTGTTCCGGAACATCTCCACAACAGC
TTGTATAGTCCTGAAAATATCATCTACACTTTAGGATACGATAAAAAAAATCTTTCTCAACACGAACTAAAAATGATCAT
GATAGAGCATCTAGGTCGTGCAGCTCCCTTTAATGGTACCTATTGTGCATCTCCAAATATGGAGATTCTCTATGATATAC
TATGGAGTGAGTGTCATGTTATGCGCCACTGTTAG

Upstream 100 bases:

>100_bases
CTCAAACAGGACGTCATGATCCTTGTGTCGCCATACGCGCTGTCCCTGTTGTTGAGGCTATGATAAACCTTGTTCTTGCA
GATCTTGTATTATACCAACG

Downstream 100 bases:

>100_bases
CGGTCCCTCATTTTGTGAAGCAAAACAACAAATTCTAAAGTCTCTACACCTTGTAGATATTATAGAACTACGACTCGATC
TCATAAACGAACTTGATGAT

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 384; Mature: 384

Protein sequence:

>384_residues
MLQTMMSETIITTPHVVKLISNFFQKKLFSSISTAYPLVIITDVSVQQHLLGPILDHIKMLGYQVIVLTFPPGEPNKTWE
TFISLQYQLVDQNISPKSSIIGIGGGTVLDMTGFLAATYCRGLPLYLIPTTITAMVDTSIGGKNGINLRGIKNRLGTFYL
PKEVWMCPQFLSTLPREEWYHGIAEAIKHGFIADAYLWEFLNSHSKMLFSSSQILHEFIKRNCQIKAAIVAEDPYDRSLR
KILNFGHSIAHAIETLAKGTVNHGQAVSVGMMIETRISLAEGVMKTPQLIDQLERLLKRFNLPSTLKDLQSIVPEHLHNS
LYSPENIIYTLGYDKKNLSQHELKMIMIEHLGRAAPFNGTYCASPNMEILYDILWSECHVMRHC

Sequences:

>Translated_384_residues
MLQTMMSETIITTPHVVKLISNFFQKKLFSSISTAYPLVIITDVSVQQHLLGPILDHIKMLGYQVIVLTFPPGEPNKTWE
TFISLQYQLVDQNISPKSSIIGIGGGTVLDMTGFLAATYCRGLPLYLIPTTITAMVDTSIGGKNGINLRGIKNRLGTFYL
PKEVWMCPQFLSTLPREEWYHGIAEAIKHGFIADAYLWEFLNSHSKMLFSSSQILHEFIKRNCQIKAAIVAEDPYDRSLR
KILNFGHSIAHAIETLAKGTVNHGQAVSVGMMIETRISLAEGVMKTPQLIDQLERLLKRFNLPSTLKDLQSIVPEHLHNS
LYSPENIIYTLGYDKKNLSQHELKMIMIEHLGRAAPFNGTYCASPNMEILYDILWSECHVMRHC
>Mature_384_residues
MLQTMMSETIITTPHVVKLISNFFQKKLFSSISTAYPLVIITDVSVQQHLLGPILDHIKMLGYQVIVLTFPPGEPNKTWE
TFISLQYQLVDQNISPKSSIIGIGGGTVLDMTGFLAATYCRGLPLYLIPTTITAMVDTSIGGKNGINLRGIKNRLGTFYL
PKEVWMCPQFLSTLPREEWYHGIAEAIKHGFIADAYLWEFLNSHSKMLFSSSQILHEFIKRNCQIKAAIVAEDPYDRSLR
KILNFGHSIAHAIETLAKGTVNHGQAVSVGMMIETRISLAEGVMKTPQLIDQLERLLKRFNLPSTLKDLQSIVPEHLHNS
LYSPENIIYTLGYDKKNLSQHELKMIMIEHLGRAAPFNGTYCASPNMEILYDILWSECHVMRHC

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789791, Length=339, Percent_Identity=29.7935103244838, Blast_Score=139, Evalue=2e-34,
Organism=Saccharomyces cerevisiae, GI6320332, Length=338, Percent_Identity=28.9940828402367, Blast_Score=150, Evalue=4e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037 [H]

Pfam domain/function: PF01761 DHQ_synthase [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 43335; Mature: 43335

Theoretical pI: Translated: 7.93; Mature: 7.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQTMMSETIITTPHVVKLISNFFQKKLFSSISTAYPLVIITDVSVQQHLLGPILDHIKM
CCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHH
LGYQVIVLTFPPGEPNKTWETFISLQYQLVDQNISPKSSIIGIGGGTVLDMTGFLAATYC
HCEEEEEEEECCCCCCHHHHHHHHHHHHEECCCCCCCCCEEECCCCHHHHHHHHHHHHHH
RGLPLYLIPTTITAMVDTSIGGKNGINLRGIKNRLGTFYLPKEVWMCPQFLSTLPREEWY
CCCCEEEHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCEECCHHHHHHHHHHHHCCHHHHH
HGIAEAIKHGFIADAYLWEFLNSHSKMLFSSSQILHEFIKRNCQIKAAIVAEDPYDRSLR
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCHHHHHH
KILNFGHSIAHAIETLAKGTVNHGQAVSVGMMIETRISLAEGVMKTPQLIDQLERLLKRF
HHHHHCHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHCCHHHHHHHHHHHHHC
NLPSTLKDLQSIVPEHLHNSLYSPENIIYTLGYDKKNLSQHELKMIMIEHLGRAAPFNGT
CCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCE
YCASPNMEILYDILWSECHVMRHC
EECCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLQTMMSETIITTPHVVKLISNFFQKKLFSSISTAYPLVIITDVSVQQHLLGPILDHIKM
CCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHH
LGYQVIVLTFPPGEPNKTWETFISLQYQLVDQNISPKSSIIGIGGGTVLDMTGFLAATYC
HCEEEEEEEECCCCCCHHHHHHHHHHHHEECCCCCCCCCEEECCCCHHHHHHHHHHHHHH
RGLPLYLIPTTITAMVDTSIGGKNGINLRGIKNRLGTFYLPKEVWMCPQFLSTLPREEWY
CCCCEEEHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCEECCHHHHHHHHHHHHCCHHHHH
HGIAEAIKHGFIADAYLWEFLNSHSKMLFSSSQILHEFIKRNCQIKAAIVAEDPYDRSLR
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCHHHHHH
KILNFGHSIAHAIETLAKGTVNHGQAVSVGMMIETRISLAEGVMKTPQLIDQLERLLKRF
HHHHHCHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHCCHHHHHHHHHHHHHC
NLPSTLKDLQSIVPEHLHNSLYSPENIIYTLGYDKKNLSQHELKMIMIEHLGRAAPFNGT
CCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCE
YCASPNMEILYDILWSECHVMRHC
EECCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362 [H]