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The map label for this gene is aroC

Identifier: 15618945

GI number: 15618945

Start: 1191120

End: 1192199

Strand: Reverse

Name: aroC

Synonym: CPn1037

Alternate gene names: 15618945

Gene position: 1192199-1191120 (Counterclockwise)

Preceding gene: 15618946

Following gene: 15618944

Centisome position: 96.91

GC content: 46.39

Gene sequence:

>1080_bases
ATGAAAAATAGCTTTGGCTCTTTGTTTTCTTTTACAACATGGGGAGAATCCCACGGTCCCTCAATCGGAGTTGTAATCGA
TGGTTGTCCCGCAGGACTCGAGCTCCATGAATCAGATTTTGTTCCTGCCATGAAGCGCCGTCGTCCAGGAAATCCAGGAA
CCTCATCGCGCAAAGAAAACGATATCGTGCAAATCCTCTCTGGAGTTTATAAAGGAAAGACCACAGGCACTCCCCTATCC
CTGCAAATCCTCAATACTGACGTAGATAGCTCCCCTTATGAAAACAGTGAAAGGCTCTACCGTCCTGGCCACTCCCAATA
TACCTATGAAAAGAAATTCGGAATTGTAGATCCTAACGGAGGAGGTCGCTCCTCAGCTCGAGAGACGGCATGTCGCGTCG
CTGCTGGCGTAGTTGCAGAGAAATTCCTCGCGAATCAAAACATTTTTACTTTAGCCTACCTCTCCTCGTTAGGATCTCTA
ACCCTCCCTCACTACCTGAAGATCTCCCCCGAGCTCATCCACAAGATTCACACCTCGCCATTCTATTCACCGTTACCTAA
TGAGAAAATCCAAGAGATCCTTACTTCTCTACACGACGACTCTGATTCTCTAGGTGGGGTGATTTCTTTCATAACGTCTC
CAATCCACGACTTTCTAGGGGAACCCCTCTTTGGGAAAGTGCACGCCCTCTTAGCAAGTGCTTTAATGAGCATCCCCGCC
GCTAAAGGATTCGAAATAGGAAAAGGGTTTGCCTCTGCTCAAATGAGAGGTTCACAATATACTGATCCCTTCGTCATGGA
AGGAGAAAACATTACCTTGAAGTCTAACAACTGTGGAGGCACACTAGGAGGCATAACTATAGGAGTTCCTATAGAAGGGC
GCATAGCATTTAAACCTACCTCTTCGATAAAGCGACCCTGTGCTACAGTGACAAAGACAAAAAAAGAAACTACCTATAGG
ACACCTCAAACAGGACGTCATGATCCTTGTGTCGCCATACGCGCTGTCCCTGTTGTTGAGGCTATGATAAACCTTGTTCT
TGCAGATCTTGTATTATACCAACGATGCTCCAAACTATGA

Upstream 100 bases:

>100_bases
AAGAAATTGCTGATTACATTTTTCCCGTGGATCACGTAGATCATTCCTCGAAGAGCTCCTTAGAACAAGCGTCTCAAGAT
CTCATTACCTTGTTAAAGTC

Downstream 100 bases:

>100_bases
TGTCAGAGACAATAATTACGACTCCCCATGTAGTGAAACTCATATCCAACTTCTTCCAGAAGAAGTTGTTCTCTTCTATA
TCCACAGCGTATCCCTTAGT

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase

Number of amino acids: Translated: 359; Mature: 359

Protein sequence:

>359_residues
MKNSFGSLFSFTTWGESHGPSIGVVIDGCPAGLELHESDFVPAMKRRRPGNPGTSSRKENDIVQILSGVYKGKTTGTPLS
LQILNTDVDSSPYENSERLYRPGHSQYTYEKKFGIVDPNGGGRSSARETACRVAAGVVAEKFLANQNIFTLAYLSSLGSL
TLPHYLKISPELIHKIHTSPFYSPLPNEKIQEILTSLHDDSDSLGGVISFITSPIHDFLGEPLFGKVHALLASALMSIPA
AKGFEIGKGFASAQMRGSQYTDPFVMEGENITLKSNNCGGTLGGITIGVPIEGRIAFKPTSSIKRPCATVTKTKKETTYR
TPQTGRHDPCVAIRAVPVVEAMINLVLADLVLYQRCSKL

Sequences:

>Translated_359_residues
MKNSFGSLFSFTTWGESHGPSIGVVIDGCPAGLELHESDFVPAMKRRRPGNPGTSSRKENDIVQILSGVYKGKTTGTPLS
LQILNTDVDSSPYENSERLYRPGHSQYTYEKKFGIVDPNGGGRSSARETACRVAAGVVAEKFLANQNIFTLAYLSSLGSL
TLPHYLKISPELIHKIHTSPFYSPLPNEKIQEILTSLHDDSDSLGGVISFITSPIHDFLGEPLFGKVHALLASALMSIPA
AKGFEIGKGFASAQMRGSQYTDPFVMEGENITLKSNNCGGTLGGITIGVPIEGRIAFKPTSSIKRPCATVTKTKKETTYR
TPQTGRHDPCVAIRAVPVVEAMINLVLADLVLYQRCSKL
>Mature_359_residues
MKNSFGSLFSFTTWGESHGPSIGVVIDGCPAGLELHESDFVPAMKRRRPGNPGTSSRKENDIVQILSGVYKGKTTGTPLS
LQILNTDVDSSPYENSERLYRPGHSQYTYEKKFGIVDPNGGGRSSARETACRVAAGVVAEKFLANQNIFTLAYLSSLGSL
TLPHYLKISPELIHKIHTSPFYSPLPNEKIQEILTSLHDDSDSLGGVISFITSPIHDFLGEPLFGKVHALLASALMSIPA
AKGFEIGKGFASAQMRGSQYTDPFVMEGENITLKSNNCGGTLGGITIGVPIEGRIAFKPTSSIKRPCATVTKTKKETTYR
TPQTGRHDPCVAIRAVPVVEAMINLVLADLVLYQRCSKL

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family

Homologues:

Organism=Escherichia coli, GI1788669, Length=359, Percent_Identity=44.2896935933148, Blast_Score=271, Evalue=7e-74,
Organism=Saccharomyces cerevisiae, GI6321290, Length=370, Percent_Identity=41.3513513513514, Blast_Score=267, Evalue=2e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROC_CHLPN (Q9Z6M2)

Other databases:

- EMBL:   AE001363
- EMBL:   AE002161
- EMBL:   BA000008
- EMBL:   AE009440
- PIR:   A72004
- PIR:   B86620
- RefSeq:   NP_225231.1
- RefSeq:   NP_301092.1
- RefSeq:   NP_445354.1
- RefSeq:   NP_877349.1
- ProteinModelPortal:   Q9Z6M2
- GeneID:   1467756
- GeneID:   894701
- GeneID:   919812
- GeneID:   962765
- GenomeReviews:   AE001363_GR
- GenomeReviews:   AE002161_GR
- GenomeReviews:   AE009440_GR
- GenomeReviews:   BA000008_GR
- KEGG:   cpa:CP0815
- KEGG:   cpn:CPn1037
- KEGG:   cpt:CpB1077
- TIGR:   CP_0815
- HOGENOM:   HBG292336
- OMA:   SRFTTQR
- PhylomeDB:   Q9Z6M2
- ProtClustDB:   PRK05382
- BioCyc:   CPNE115711:CP_0815-MONOMER
- BioCyc:   CPNE115713:CPN1037-MONOMER
- BioCyc:   CPNE138677:CPJ1037-MONOMER
- BioCyc:   CPNE182082:CPB1077-MONOMER
- BRENDA:   4.2.3.5
- HAMAP:   MF_00300_B
- InterPro:   IPR000453
- InterPro:   IPR020541
- PANTHER:   PTHR21085
- PIRSF:   PIRSF001456
- TIGRFAMs:   TIGR00033

Pfam domain/function: PF01264 Chorismate_synt; SSF103263 Chorismate_synth

EC number: =4.2.3.5

Molecular weight: Translated: 38804; Mature: 38804

Theoretical pI: Translated: 8.74; Mature: 8.74

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1; PS00788 CHORISMATE_SYNTHASE_2; PS00789 CHORISMATE_SYNTHASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNSFGSLFSFTTWGESHGPSIGVVIDGCPAGLELHESDFVPAMKRRRPGNPGTSSRKEN
CCCCCCCHHEEECCCCCCCCEEEEEEECCCCCCEECCCCCCHHHHHCCCCCCCCCCCCHH
DIVQILSGVYKGKTTGTPLSLQILNTDVDSSPYENSERLYRPGHSQYTYEKKFGIVDPNG
HHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCCCHHHCCCCCCCEEEHHCCCEECCCC
GGRSSARETACRVAAGVVAEKFLANQNIFTLAYLSSLGSLTLPHYLKISPELIHKIHTSP
CCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCHHEECCHHHHHHHHCCC
FYSPLPNEKIQEILTSLHDDSDSLGGVISFITSPIHDFLGEPLFGKVHALLASALMSIPA
CCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCC
AKGFEIGKGFASAQMRGSQYTDPFVMEGENITLKSNNCGGTLGGITIGVPIEGRIAFKPT
CCCCHHCCCHHHHHHCCCCCCCCEEEECCEEEEECCCCCCEECCEEEECCCCCEEEECCC
SSIKRPCATVTKTKKETTYRTPQTGRHDPCVAIRAVPVVEAMINLVLADLVLYQRCSKL
HHHHCCHHHHHHCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKNSFGSLFSFTTWGESHGPSIGVVIDGCPAGLELHESDFVPAMKRRRPGNPGTSSRKEN
CCCCCCCHHEEECCCCCCCCEEEEEEECCCCCCEECCCCCCHHHHHCCCCCCCCCCCCHH
DIVQILSGVYKGKTTGTPLSLQILNTDVDSSPYENSERLYRPGHSQYTYEKKFGIVDPNG
HHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCCCHHHCCCCCCCEEEHHCCCEECCCC
GGRSSARETACRVAAGVVAEKFLANQNIFTLAYLSSLGSLTLPHYLKISPELIHKIHTSP
CCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCHHEECCHHHHHHHHCCC
FYSPLPNEKIQEILTSLHDDSDSLGGVISFITSPIHDFLGEPLFGKVHALLASALMSIPA
CCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCC
AKGFEIGKGFASAQMRGSQYTDPFVMEGENITLKSNNCGGTLGGITIGVPIEGRIAFKPT
CCCCHHCCCHHHHHHCCCCCCCCEEEECCEEEEECCCCCCEECCEEEECCCCCEEEECCC
SSIKRPCATVTKTKKETTYRTPQTGRHDPCVAIRAVPVVEAMINLVLADLVLYQRCSKL
HHHHCCHHHHHHCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362