Click here to switch to the map view.

The map label for this gene is yggV

Identifier: 15618684

GI number: 15618684

Start: 873411

End: 874031

Strand: Reverse

Name: yggV

Synonym: CPn0775

Alternate gene names: 15618684

Gene position: 874031-873411 (Counterclockwise)

Preceding gene: 15618688

Following gene: 15618681

Centisome position: 71.05

GC content: 41.55

Gene sequence:

>621_bases
ATGAAAATTGTGATTGCTAGTTCTCATGGTTATAAAATACGAGAAACCAAGACTTTTTTAAAGCGTTTAGGTGATTTCGA
TATTTTTTCTCTTTCTGATTTTCCTGACTATAAACTTCCCCAAGAACAGGGAGATTCTATAACGGCGAACGCCCTTACTA
AAGGGATTCACGCTGCCAATCATTTGGGTTGCTGGGTCATTGCGGATGATACGATGTTACGCGTCCCCGCTTTAAATGGT
CTTCCGGGTCCTTTATCTGCGAACTTTGCTGGTGTAGGTGCGTATGATAAAGATCATCGAAAAAAGCTGCTTGATCTTAT
GTCGTCTTTGGAAAGCCTCGTAGACCGTTCTGCGTACTTCGAGTGTTGTGTAGTTTTAGTCTCCCCTAATCAGGAGATTT
TTAAAACGTATGGGATATGCGAGGGCTACATCAGCCATCAAGAAAAAGGTTCTTCAGGGTTCGGCTACGACCCTATCTTT
GTAAAATATGATTACAAACAAACATTTGCCGAGCTTAGTGAAGATGTGAAAAATCAAGTTTCTCACAGAGCAAAGGCATT
GCAAAAACTCGCCCCTCACCTGCAAAGCTTATTTGAAAAACACCTACTCACTAGGGACTAG

Upstream 100 bases:

>100_bases
ACTTTAACTACAAAGATTTTCATCGGCTAATAATTGCGCATTACGCTTGCTGACTCTATCTTGTTAAAACTTTATAATTT
CAAAAGATTAAGAAAGATTC

Downstream 100 bases:

>100_bases
TGTTCGCAAAGATTGCTCCAAGCAACCACGAATTTCTCGCATTTCTGCTAACAGAGCTTCTGCTCGTAAAAAATCCGCTT
CCAAATTAGCAACCGAGGGC

Product: deoxyribonucleotide triphosphate pyrophosphatase

Products: NA

Alternate protein names: Nucleoside triphosphate phosphohydrolase; NTPase [H]

Number of amino acids: Translated: 206; Mature: 206

Protein sequence:

>206_residues
MKIVIASSHGYKIRETKTFLKRLGDFDIFSLSDFPDYKLPQEQGDSITANALTKGIHAANHLGCWVIADDTMLRVPALNG
LPGPLSANFAGVGAYDKDHRKKLLDLMSSLESLVDRSAYFECCVVLVSPNQEIFKTYGICEGYISHQEKGSSGFGYDPIF
VKYDYKQTFAELSEDVKNQVSHRAKALQKLAPHLQSLFEKHLLTRD

Sequences:

>Translated_206_residues
MKIVIASSHGYKIRETKTFLKRLGDFDIFSLSDFPDYKLPQEQGDSITANALTKGIHAANHLGCWVIADDTMLRVPALNG
LPGPLSANFAGVGAYDKDHRKKLLDLMSSLESLVDRSAYFECCVVLVSPNQEIFKTYGICEGYISHQEKGSSGFGYDPIF
VKYDYKQTFAELSEDVKNQVSHRAKALQKLAPHLQSLFEKHLLTRD
>Mature_206_residues
MKIVIASSHGYKIRETKTFLKRLGDFDIFSLSDFPDYKLPQEQGDSITANALTKGIHAANHLGCWVIADDTMLRVPALNG
LPGPLSANFAGVGAYDKDHRKKLLDLMSSLESLVDRSAYFECCVVLVSPNQEIFKTYGICEGYISHQEKGSSGFGYDPIF
VKYDYKQTFAELSEDVKNQVSHRAKALQKLAPHLQSLFEKHLLTRD

Specific function: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions [H]

COG id: COG0127

COG function: function code F; Xanthosine triphosphate pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAM1 NTPase family [H]

Homologues:

Organism=Homo sapiens, GI15626999, Length=202, Percent_Identity=32.6732673267327, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI31657144, Length=167, Percent_Identity=34.1317365269461, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1789324, Length=197, Percent_Identity=34.010152284264, Blast_Score=100, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI17556833, Length=198, Percent_Identity=30.8080808080808, Blast_Score=75, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6322529, Length=201, Percent_Identity=30.3482587064677, Blast_Score=67, Evalue=2e-12,
Organism=Drosophila melanogaster, GI19920712, Length=160, Percent_Identity=36.25, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002637
- InterPro:   IPR020922 [H]

Pfam domain/function: PF01725 Ham1p_like [H]

EC number: =3.6.1.15 [H]

Molecular weight: Translated: 23064; Mature: 23064

Theoretical pI: Translated: 7.23; Mature: 7.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIVIASSHGYKIRETKTFLKRLGDFDIFSLSDFPDYKLPQEQGDSITANALTKGIHAAN
CEEEEECCCCCCHHHHHHHHHHHCCCCEEECCCCCCCCCCHHCCCCEEHHHHHHHHHHHH
HLGCWVIADDTMLRVPALNGLPGPLSANFAGVGAYDKDHRKKLLDLMSSLESLVDRSAYF
HCEEEEEECCCEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
ECCVVLVSPNQEIFKTYGICEGYISHQEKGSSGFGYDPIFVKYDYKQTFAELSEDVKNQV
HEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHH
SHRAKALQKLAPHLQSLFEKHLLTRD
HHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKIVIASSHGYKIRETKTFLKRLGDFDIFSLSDFPDYKLPQEQGDSITANALTKGIHAAN
CEEEEECCCCCCHHHHHHHHHHHCCCCEEECCCCCCCCCCHHCCCCEEHHHHHHHHHHHH
HLGCWVIADDTMLRVPALNGLPGPLSANFAGVGAYDKDHRKKLLDLMSSLESLVDRSAYF
HCEEEEEECCCEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
ECCVVLVSPNQEIFKTYGICEGYISHQEKGSSGFGYDPIFVKYDYKQTFAELSEDVKNQV
HEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHH
SHRAKALQKLAPHLQSLFEKHLLTRD
HHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362 [H]