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The map label for this gene is aspC1

Identifier: 15606968

GI number: 15606968

Start: 1386624

End: 1387808

Strand: Direct

Name: aspC1

Synonym: aq_1969

Alternate gene names: 15606968

Gene position: 1386624-1387808 (Clockwise)

Preceding gene: 15606967

Following gene: 15606972

Centisome position: 89.38

GC content: 45.15

Gene sequence:

>1185_bases
ATGAGAAAAGGACTTGCAAGTAGGGTAAGTCACCTAAAACCTTCCCCCACGCTGACCATAACCGCAAAAGCAAAAGAATT
AAGGGCTAAAGGAGTGGACGTTATAGGTTTTGGAGCGGGAGAACCTGACTTCGACACACCCGACTTCATAAAGGAAGCCT
GTATAAGGGCTTTAAGGGAAGGAAAGACCAAGTACGCTCCCTCCGCGGGAATACCAGAGCTCAGAGAAGCTATAGCTGAA
AAACTACTGAAAGAAAACAAAGTTGAGTACAAACCTTCAGAGATAGTCGTTTCCGCAGGAGCGAAAATGGTTCTCTTCCT
CATATTCATGGCTATACTGGACGAAGGAGACGAGGTTTTACTACCTAGCCCTTACTGGGTAACTTACCCCGAACAGATAA
GGTTCTTCGGAGGGGTTCCCGTTGAGGTTCCTCTAAAGAAAGAGAAAGGATTTCAATTAAGTCTGGAAGATGTGAAAGAA
AAGGTTACGGAGAGAACAAAAGCTATAGTCATAAACTCTCCGAACAACCCCACTGGTGCTGTTTACGAAGAGGAGGAACT
TAAGAAAATAGCGGAGTTTTGCGTGGAGAGGGGCATTTTCATAATTTCCGATGAGTGCTATGAGTACTTCGTTTACGGTG
ATGCAAAATTTGTTAGCCCTGCCTCTTTCTCGGATGAAGTAAAGAACATAACCTTCACGGTAAACGCCTTTTCGAAGAGC
TATTCCATGACTGGTTGGCGAATAGGTTATGTAGCGTGCCCCGAAGAGTACGCAAAAGTGATAGCGAGTCTTAACAGCCA
GAGTGTTTCCAACGTCACTACCTTTGCCCAGTATGGAGCTCTTGAGGCCTTGAAAAATCCAAAGTCTAAAGATTTTGTAA
ACGAAATGAGAAATGCTTTTGAAAGGAGAAGGGATACGGCTGTAGAAGAGCTTTCTAAAATTCCAGGTATGGATGTGGTA
AAACCCGAAGGTGCCTTTTACATATTTCCGGACTTCTCCGCTTACGCTGAGAAACTGGGTGGTGATGTGAAACTCTCGGA
GTTCCTTCTGGAAAAGGCTAAGGTTGCGGTGGTTCCCGGTTCGGCCTTCGGAGCTCCCGGATTTTTGAGGCTTTCTTACG
CCCTTTCCGAGGAAAGACTCGTTGAGGGTATAAGGAGAATAAAGAAAGCCCTTGAAGAGATCTAA

Upstream 100 bases:

>100_bases
CTCCAAGGACATTCCCCTTTCTTCTCTGATCTTCCTTATCCTCTCTCCCACTCCAATCATGGCTCCACCTCCTCCCTTTT
TAATTTAAAATTTTAAGGAA

Downstream 100 bases:

>100_bases
ACGGCCAGAACCCTATTCACTTCCTCTATAGATGTTATTCCTCTCTTTACCTTCAGAAGGCCATTCTTGTAAAGGGTTCT
CATTCCCTTTTCTATCGCCT

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A

Number of amino acids: Translated: 394; Mature: 394

Protein sequence:

>394_residues
MRKGLASRVSHLKPSPTLTITAKAKELRAKGVDVIGFGAGEPDFDTPDFIKEACIRALREGKTKYAPSAGIPELREAIAE
KLLKENKVEYKPSEIVVSAGAKMVLFLIFMAILDEGDEVLLPSPYWVTYPEQIRFFGGVPVEVPLKKEKGFQLSLEDVKE
KVTERTKAIVINSPNNPTGAVYEEEELKKIAEFCVERGIFIISDECYEYFVYGDAKFVSPASFSDEVKNITFTVNAFSKS
YSMTGWRIGYVACPEEYAKVIASLNSQSVSNVTTFAQYGALEALKNPKSKDFVNEMRNAFERRRDTAVEELSKIPGMDVV
KPEGAFYIFPDFSAYAEKLGGDVKLSEFLLEKAKVAVVPGSAFGAPGFLRLSYALSEERLVEGIRRIKKALEEI

Sequences:

>Translated_394_residues
MRKGLASRVSHLKPSPTLTITAKAKELRAKGVDVIGFGAGEPDFDTPDFIKEACIRALREGKTKYAPSAGIPELREAIAE
KLLKENKVEYKPSEIVVSAGAKMVLFLIFMAILDEGDEVLLPSPYWVTYPEQIRFFGGVPVEVPLKKEKGFQLSLEDVKE
KVTERTKAIVINSPNNPTGAVYEEEELKKIAEFCVERGIFIISDECYEYFVYGDAKFVSPASFSDEVKNITFTVNAFSKS
YSMTGWRIGYVACPEEYAKVIASLNSQSVSNVTTFAQYGALEALKNPKSKDFVNEMRNAFERRRDTAVEELSKIPGMDVV
KPEGAFYIFPDFSAYAEKLGGDVKLSEFLLEKAKVAVVPGSAFGAPGFLRLSYALSEERLVEGIRRIKKALEEI
>Mature_394_residues
MRKGLASRVSHLKPSPTLTITAKAKELRAKGVDVIGFGAGEPDFDTPDFIKEACIRALREGKTKYAPSAGIPELREAIAE
KLLKENKVEYKPSEIVVSAGAKMVLFLIFMAILDEGDEVLLPSPYWVTYPEQIRFFGGVPVEVPLKKEKGFQLSLEDVKE
KVTERTKAIVINSPNNPTGAVYEEEELKKIAEFCVERGIFIISDECYEYFVYGDAKFVSPASFSDEVKNITFTVNAFSKS
YSMTGWRIGYVACPEEYAKVIASLNSQSVSNVTTFAQYGALEALKNPKSKDFVNEMRNAFERRRDTAVEELSKIPGMDVV
KPEGAFYIFPDFSAYAEKLGGDVKLSEFLLEKAKVAVVPGSAFGAPGFLRLSYALSEERLVEGIRRIKKALEEI

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family

Homologues:

Organism=Homo sapiens, GI56713254, Length=355, Percent_Identity=29.2957746478873, Blast_Score=164, Evalue=2e-40,
Organism=Homo sapiens, GI56713256, Length=355, Percent_Identity=29.2957746478873, Blast_Score=164, Evalue=2e-40,
Organism=Homo sapiens, GI95147551, Length=360, Percent_Identity=28.8888888888889, Blast_Score=163, Evalue=2e-40,
Organism=Homo sapiens, GI169881279, Length=360, Percent_Identity=28.8888888888889, Blast_Score=163, Evalue=2e-40,
Organism=Homo sapiens, GI4507369, Length=384, Percent_Identity=25.78125, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI169881281, Length=357, Percent_Identity=24.3697478991597, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI187936925, Length=358, Percent_Identity=25.1396648044693, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI14211921, Length=358, Percent_Identity=25.1396648044693, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI19263340, Length=371, Percent_Identity=25.0673854447439, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI215599424, Length=371, Percent_Identity=25.0673854447439, Blast_Score=89, Evalue=9e-18,
Organism=Homo sapiens, GI149944424, Length=370, Percent_Identity=23.2432432432432, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI4885351, Length=377, Percent_Identity=24.6684350132626, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI7705897, Length=405, Percent_Identity=25.679012345679, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI33469970, Length=405, Percent_Identity=25.679012345679, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI1786816, Length=368, Percent_Identity=27.7173913043478, Blast_Score=169, Evalue=4e-43,
Organism=Escherichia coli, GI1788627, Length=360, Percent_Identity=31.3888888888889, Blast_Score=160, Evalue=9e-41,
Organism=Escherichia coli, GI1788722, Length=393, Percent_Identity=31.5521628498728, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1790797, Length=334, Percent_Identity=23.9520958083832, Blast_Score=67, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17567663, Length=368, Percent_Identity=28.804347826087, Blast_Score=154, Evalue=5e-38,
Organism=Caenorhabditis elegans, GI71994472, Length=384, Percent_Identity=26.3020833333333, Blast_Score=152, Evalue=4e-37,
Organism=Caenorhabditis elegans, GI71994476, Length=384, Percent_Identity=26.3020833333333, Blast_Score=151, Evalue=5e-37,
Organism=Caenorhabditis elegans, GI17567369, Length=357, Percent_Identity=25.7703081232493, Blast_Score=132, Evalue=4e-31,
Organism=Caenorhabditis elegans, GI71981209, Length=342, Percent_Identity=23.9766081871345, Blast_Score=66, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6322401, Length=399, Percent_Identity=27.5689223057644, Blast_Score=149, Evalue=9e-37,
Organism=Saccharomyces cerevisiae, GI6320317, Length=371, Percent_Identity=26.1455525606469, Blast_Score=97, Evalue=6e-21,
Organism=Saccharomyces cerevisiae, GI6323118, Length=365, Percent_Identity=26.027397260274, Blast_Score=93, Evalue=9e-20,
Organism=Drosophila melanogaster, GI28573069, Length=356, Percent_Identity=26.9662921348315, Blast_Score=138, Evalue=8e-33,
Organism=Drosophila melanogaster, GI24646114, Length=356, Percent_Identity=26.9662921348315, Blast_Score=138, Evalue=8e-33,
Organism=Drosophila melanogaster, GI28573067, Length=356, Percent_Identity=26.9662921348315, Blast_Score=138, Evalue=8e-33,
Organism=Drosophila melanogaster, GI28573065, Length=356, Percent_Identity=26.9662921348315, Blast_Score=138, Evalue=8e-33,
Organism=Drosophila melanogaster, GI18859735, Length=376, Percent_Identity=24.7340425531915, Blast_Score=124, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24641770, Length=367, Percent_Identity=27.2479564032698, Blast_Score=95, Evalue=7e-20,
Organism=Drosophila melanogaster, GI24641760, Length=367, Percent_Identity=27.2479564032698, Blast_Score=95, Evalue=7e-20,
Organism=Drosophila melanogaster, GI24641768, Length=367, Percent_Identity=27.2479564032698, Blast_Score=95, Evalue=7e-20,
Organism=Drosophila melanogaster, GI24641766, Length=367, Percent_Identity=27.2479564032698, Blast_Score=95, Evalue=7e-20,
Organism=Drosophila melanogaster, GI24641764, Length=367, Percent_Identity=27.2479564032698, Blast_Score=95, Evalue=7e-20,
Organism=Drosophila melanogaster, GI45551451, Length=367, Percent_Identity=27.2479564032698, Blast_Score=95, Evalue=8e-20,
Organism=Drosophila melanogaster, GI21356535, Length=397, Percent_Identity=23.9294710327456, Blast_Score=80, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AAT_AQUAE (O67781)

Other databases:

- EMBL:   AE000657
- PIR:   A70469
- RefSeq:   NP_214350.1
- ProteinModelPortal:   O67781
- SMR:   O67781
- GeneID:   1193678
- GenomeReviews:   AE000657_GR
- KEGG:   aae:aq_1969
- NMPDR:   fig|224324.1.peg.1365
- HOGENOM:   HBG645860
- OMA:   EIYELIL
- PhylomeDB:   O67781
- ProtClustDB:   CLSK2299887
- BioCyc:   AAEO224324:AQ_1969-MONOMER
- BRENDA:   2.6.1.1
- GO:   GO:0005737
- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- Gene3D:   G3DSA:3.40.640.10
- Gene3D:   G3DSA:3.90.1150.10
- PRINTS:   PR00753

Pfam domain/function: PF00155 Aminotran_1_2; SSF53383 PyrdxlP-dep_Trfase_major

EC number: =2.6.1.1

Molecular weight: Translated: 43778; Mature: 43778

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: PS00105 AA_TRANSFER_CLASS_1; PS00217 SUGAR_TRANSPORT_2

Important sites: BINDING 40-40 BINDING 126-126 BINDING 176-176

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKGLASRVSHLKPSPTLTITAKAKELRAKGVDVIGFGAGEPDFDTPDFIKEACIRALRE
CCCCHHHHHHHCCCCCCEEEEECHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHHC
GKTKYAPSAGIPELREAIAEKLLKENKVEYKPSEIVVSAGAKMVLFLIFMAILDEGDEVL
CCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEECCCHHHHHHHHHHHHHCCCCCEE
LPSPYWVTYPEQIRFFGGVPVEVPLKKEKGFQLSLEDVKEKVTERTKAIVINSPNNPTGA
ECCCCEECCHHHHHHHCCCCEEECCCCCCCCEEEHHHHHHHHHHHHEEEEEECCCCCCCC
VYEEEELKKIAEFCVERGIFIISDECYEYFVYGDAKFVSPASFSDEVKNITFTVNAFSKS
CCCHHHHHHHHHHHHHCCEEEEECCCEEEEEECCCCCCCCCCCCCCCCEEEEEEEECCCC
YSMTGWRIGYVACPEEYAKVIASLNSQSVSNVTTFAQYGALEALKNPKSKDFVNEMRNAF
CCCCCEEEEEEECCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
ERRRDTAVEELSKIPGMDVVKPEGAFYIFPDFSAYAEKLGGDVKLSEFLLEKAKVAVVPG
HHHHHHHHHHHHHCCCCCEECCCCCEEECCCHHHHHHHCCCCCHHHHHHHHHCCEEEECC
SAFGAPGFLRLSYALSEERLVEGIRRIKKALEEI
CCCCCCCCEEEHHHHCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRKGLASRVSHLKPSPTLTITAKAKELRAKGVDVIGFGAGEPDFDTPDFIKEACIRALRE
CCCCHHHHHHHCCCCCCEEEEECHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHHC
GKTKYAPSAGIPELREAIAEKLLKENKVEYKPSEIVVSAGAKMVLFLIFMAILDEGDEVL
CCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEECCCHHHHHHHHHHHHHCCCCCEE
LPSPYWVTYPEQIRFFGGVPVEVPLKKEKGFQLSLEDVKEKVTERTKAIVINSPNNPTGA
ECCCCEECCHHHHHHHCCCCEEECCCCCCCCEEEHHHHHHHHHHHHEEEEEECCCCCCCC
VYEEEELKKIAEFCVERGIFIISDECYEYFVYGDAKFVSPASFSDEVKNITFTVNAFSKS
CCCHHHHHHHHHHHHHCCEEEEECCCEEEEEECCCCCCCCCCCCCCCCEEEEEEEECCCC
YSMTGWRIGYVACPEEYAKVIASLNSQSVSNVTTFAQYGALEALKNPKSKDFVNEMRNAF
CCCCCEEEEEEECCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
ERRRDTAVEELSKIPGMDVVKPEGAFYIFPDFSAYAEKLGGDVKLSEFLLEKAKVAVVPG
HHHHHHHHHHHHHCCCCCEECCCCCEEECCCHHHHHHHCCCCCHHHHHHHHHCCEEEECC
SAFGAPGFLRLSYALSEERLVEGIRRIKKALEEI
CCCCCCCCEEEHHHHCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9537320