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The map label for this gene is mtnD

Identifier: 15606972

GI number: 15606972

Start: 1390681

End: 1391232

Strand: Direct

Name: mtnD

Synonym: aq_1975

Alternate gene names: 15606972

Gene position: 1390681-1391232 (Clockwise)

Preceding gene: 15606968

Following gene: 15606973

Centisome position: 89.64

GC content: 43.48

Gene sequence:

>552_bases
ATGAGCAGGTTGAGAATATACACGGAATCTGGAGAACTTATAAAAGACATTACTGACCCAAAGGAAATAGCTGAAGAACT
TCAGAAGATAAATGTCCTGTTTGAAAGATGGAGGGCAAACGCACCCCTAAAAGAGAACGCAAGTGACGAAGAAATTATAA
ACGCTTACAAACATGAAATAGATAGGCTAATAAACAAATATGGATTTCAGTCCTACGACGTTATAGCTATGACGCCCGAA
CACCCTAAAAAAGATGAATTGAGACAGAAGTTCCTCAAAGAGCACACCCACAGCGACTTTGAAGTGAGGTACTTCGTTTA
CGGAGACGGCGTGTTTTACCTTCACCCAAATGACAAGGTTTACATACTCCACTGTACGGCGGGAGACCTCATCAGCGTCC
CTCCGAACACTAAACACTGGTTTGACATGGGGGAAAATCCTAACTTCAAGTGTATAAGGCTCTTCACGACACCCGAAGGC
TGGGTAGCCGAATATACCGGCTCGGATATAGCGGAAAAGTTCCCCAAGTACGAGGAAGTTGTAAATGGTTAA

Upstream 100 bases:

>100_bases
AGTTGGCTTTTCTTCCGTTTTTGGTTCTTCTTTCTTAAAAAGGGAGAGTATCTTCTTGAGCACTTTTAACCTCCTGAGTT
TTACTTAAAATTTATACTTT

Downstream 100 bases:

>100_bases
GGCTATTCTTCTTGACATAGAGGGCACTATCGCACCCCTTTCCTTTGTAAAGGAAGTAATGTTTCCCTACTCAAAGAAGA
AGTTAAGGGAATTCCTTGAA

Product: hypothetical protein

Products: NA

Alternate protein names: 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; DHK-MTPene dioxygenase; Acireductone dioxygenase (Fe(2+)-requiring); ARD'; Fe-ARD; Acireductone dioxygenase (Ni(2+)-requiring); ARD; Ni-ARD

Number of amino acids: Translated: 183; Mature: 182

Protein sequence:

>183_residues
MSRLRIYTESGELIKDITDPKEIAEELQKINVLFERWRANAPLKENASDEEIINAYKHEIDRLINKYGFQSYDVIAMTPE
HPKKDELRQKFLKEHTHSDFEVRYFVYGDGVFYLHPNDKVYILHCTAGDLISVPPNTKHWFDMGENPNFKCIRLFTTPEG
WVAEYTGSDIAEKFPKYEEVVNG

Sequences:

>Translated_183_residues
MSRLRIYTESGELIKDITDPKEIAEELQKINVLFERWRANAPLKENASDEEIINAYKHEIDRLINKYGFQSYDVIAMTPE
HPKKDELRQKFLKEHTHSDFEVRYFVYGDGVFYLHPNDKVYILHCTAGDLISVPPNTKHWFDMGENPNFKCIRLFTTPEG
WVAEYTGSDIAEKFPKYEEVVNG
>Mature_182_residues
SRLRIYTESGELIKDITDPKEIAEELQKINVLFERWRANAPLKENASDEEIINAYKHEIDRLINKYGFQSYDVIAMTPEH
PKKDELRQKFLKEHTHSDFEVRYFVYGDGVFYLHPNDKVYILHCTAGDLISVPPNTKHWFDMGENPNFKCIRLFTTPEGW
VAEYTGSDIAEKFPKYEEVVNG

Specific function: Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- me

COG id: COG1791

COG function: function code S; Uncharacterized conserved protein, contains double-stranded beta-helix domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acireductone dioxygenase (ARD) family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MTND_AQUAE (O67785)

Other databases:

- EMBL:   AE000657
- PIR:   E70469
- RefSeq:   NP_214354.1
- ProteinModelPortal:   O67785
- SMR:   O67785
- GeneID:   1193682
- GenomeReviews:   AE000657_GR
- KEGG:   aae:aq_1975
- NMPDR:   fig|224324.1.peg.1369
- HOGENOM:   HBG660685
- OMA:   CEKNDLI
- PhylomeDB:   O67785
- BioCyc:   AAEO224324:AQ_1975-MONOMER
- HAMAP:   MF_01682
- InterPro:   IPR004313
- InterPro:   IPR011051
- InterPro:   IPR014710
- Gene3D:   G3DSA:2.60.120.10
- PANTHER:   PTHR23418

Pfam domain/function: PF03079 ARD; SSF51182 RmlC_like_cupin

EC number: =1.13.11.54; =1.13.11.53

Molecular weight: Translated: 21478; Mature: 21347

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRLRIYTESGELIKDITDPKEIAEELQKINVLFERWRANAPLKENASDEEIINAYKHEI
CCCEEEEECCCHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
DRLINKYGFQSYDVIAMTPEHPKKDELRQKFLKEHTHSDFEVRYFVYGDGVFYLHPNDKV
HHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEEEEEECCEEEECCCCEE
YILHCTAGDLISVPPNTKHWFDMGENPNFKCIRLFTTPEGWVAEYTGSDIAEKFPKYEEV
EEEEECCCCEEECCCCCCCEEECCCCCCEEEEEEEECCCCCEEECCCCHHHHHCCHHHHH
VNG
HCC
>Mature Secondary Structure 
SRLRIYTESGELIKDITDPKEIAEELQKINVLFERWRANAPLKENASDEEIINAYKHEI
CCEEEEECCCHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
DRLINKYGFQSYDVIAMTPEHPKKDELRQKFLKEHTHSDFEVRYFVYGDGVFYLHPNDKV
HHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEEEEEECCEEEECCCCEE
YILHCTAGDLISVPPNTKHWFDMGENPNFKCIRLFTTPEGWVAEYTGSDIAEKFPKYEEV
EEEEECCCCEEECCCCCCCEEECCCCCCEEEEEEEECCCCCEEECCCCHHHHHCCHHHHH
VNG
HCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320