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The map label for this gene is lplA [H]

Identifier: 15606952

GI number: 15606952

Start: 1372613

End: 1373650

Strand: Direct

Name: lplA [H]

Synonym: aq_1952

Alternate gene names: 15606952

Gene position: 1372613-1373650 (Clockwise)

Preceding gene: 15606950

Following gene: 15606954

Centisome position: 88.48

GC content: 44.12

Gene sequence:

>1038_bases
ATGAAGATTTACAGAGCCGGAAAGTTAGACAACCTTCGCTCCATTACCCTGTTCCACGCTATGGCAAGACTCGGGTATGA
GGGTTTGATAATAACGACACCTGTGGAGACATATGCAAGTGTAGGGTACTTTGATAAAACACAGGAAATACTTGATTTGG
AAAAGTGTAAAAAACTGGGAATTCCCGTAATAAGGAGAGAAGTGGGCGGAGGAGCTGTTTTGCTACACGAAAATCAGGTG
TTTTATCAATTAATTCTCAAAAAGAGCAGAGCTCCCTTTAAGGTTATTGACGCTTACAAGAAGTTCTCTCAACCCGTTAT
AAACGTTTACAGAAGACTGGGTGTGGAAGTGGAGTACAGACCCATAAACGACCTCGTGGTAAAGAGAAACAAGAAAAAGA
TAAGCGGACAGGGAGCCGCGGACATAGAAGACTCCTTCGTATTCGTAGGCGGGATTCTTCTGAAGTTCAACACAAAACTC
ATGGCGGAGATATTCCGGATTCCGGAGGAGAAGTTCAGGGATAAAGTTCACAAGAGCTTAGAGGAAAACGTAACCTGGGT
AGAGAGAGAAACGGGAAGACTGCCCTCTTACGAGGAAGTTGAGGAATTTCTCGTGGAAGAGTTTTCTAAAGTAATTCCCT
TTGAAGGAGAGGAACCTGTACCGGAGGAAGCAATAGAACTTGCGGACAAACTAAAAGAAGAATTCACCTCAGAAGAGGTA
CTCTTAGAGGATACGGGAAGGAAGCACAGGGCTATAAAGCTGAGGGAAGGGGTGTACTTGAGAACCGCGGTTCACAAAGC
GCAGGGAGGCTTGATCAGAACTGAAGTCTATACGGACGGAGAGGTAATAGAAAGGGTTAAAATTTACGGAGACTTTACCC
TTTATCCGAAGGAAAGCTTAAAGGAACTTGAGGAGAAACTGAAAGGGATAAAGTTTGAACCAGAAGAGATTAAAAAGGTA
GCGCACGAGTTTTTACAAAAGGTGGATATGCCGGGGGTGAGTGCTGAAGATTTAGTTATCGCCATTTACGGGGACTGA

Upstream 100 bases:

>100_bases
TCCCTTCAGTAAGTACTCCTCTCCAAAAGAGACTGCCACGAGAAGAAAAAGTATTAACGCTATCATTTTCCATTAGAGTA
TAAGACTAAATTAAAGCTTT

Downstream 100 bases:

>100_bases
AAGGGTCTTATCTTTATTATCACTCCCTCCTTACCCTTTTCTATCTTCTTTACCGTGTGCACTTCAAATATTAAGTTGTC
ATTTTTTATCACACCCGCCT

Product: hypothetical protein

Products: NA

Alternate protein names: Lipoate--protein ligase subunit 1 [H]

Number of amino acids: Translated: 345; Mature: 345

Protein sequence:

>345_residues
MKIYRAGKLDNLRSITLFHAMARLGYEGLIITTPVETYASVGYFDKTQEILDLEKCKKLGIPVIRREVGGGAVLLHENQV
FYQLILKKSRAPFKVIDAYKKFSQPVINVYRRLGVEVEYRPINDLVVKRNKKKISGQGAADIEDSFVFVGGILLKFNTKL
MAEIFRIPEEKFRDKVHKSLEENVTWVERETGRLPSYEEVEEFLVEEFSKVIPFEGEEPVPEEAIELADKLKEEFTSEEV
LLEDTGRKHRAIKLREGVYLRTAVHKAQGGLIRTEVYTDGEVIERVKIYGDFTLYPKESLKELEEKLKGIKFEPEEIKKV
AHEFLQKVDMPGVSAEDLVIAIYGD

Sequences:

>Translated_345_residues
MKIYRAGKLDNLRSITLFHAMARLGYEGLIITTPVETYASVGYFDKTQEILDLEKCKKLGIPVIRREVGGGAVLLHENQV
FYQLILKKSRAPFKVIDAYKKFSQPVINVYRRLGVEVEYRPINDLVVKRNKKKISGQGAADIEDSFVFVGGILLKFNTKL
MAEIFRIPEEKFRDKVHKSLEENVTWVERETGRLPSYEEVEEFLVEEFSKVIPFEGEEPVPEEAIELADKLKEEFTSEEV
LLEDTGRKHRAIKLREGVYLRTAVHKAQGGLIRTEVYTDGEVIERVKIYGDFTLYPKESLKELEEKLKGIKFEPEEIKKV
AHEFLQKVDMPGVSAEDLVIAIYGD
>Mature_345_residues
MKIYRAGKLDNLRSITLFHAMARLGYEGLIITTPVETYASVGYFDKTQEILDLEKCKKLGIPVIRREVGGGAVLLHENQV
FYQLILKKSRAPFKVIDAYKKFSQPVINVYRRLGVEVEYRPINDLVVKRNKKKISGQGAADIEDSFVFVGGILLKFNTKL
MAEIFRIPEEKFRDKVHKSLEENVTWVERETGRLPSYEEVEEFLVEEFSKVIPFEGEEPVPEEAIELADKLKEEFTSEEV
LLEDTGRKHRAIKLREGVYLRTAVHKAQGGLIRTEVYTDGEVIERVKIYGDFTLYPKESLKELEEKLKGIKFEPEEIKKV
AHEFLQKVDMPGVSAEDLVIAIYGD

Specific function: Lipoate-protein ligase catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes. This subunit can alone only catalyze the lipoat

COG id: COG0095

COG function: function code H; Lipoate-protein ligase A

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lplA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004143 [H]

Pfam domain/function: PF03099 BPL_LipA_LipB [H]

EC number: =2.7.7.63 [H]

Molecular weight: Translated: 39633; Mature: 39633

Theoretical pI: Translated: 5.82; Mature: 5.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIYRAGKLDNLRSITLFHAMARLGYEGLIITTPVETYASVGYFDKTQEILDLEKCKKLG
CCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEECCHHHHHHCCCCHHHHHHHHHHHHHHCC
IPVIRREVGGGAVLLHENQVFYQLILKKSRAPFKVIDAYKKFSQPVINVYRRLGVEVEYR
CHHEEHCCCCCEEEEECCHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHCCEEEEE
PINDLVVKRNKKKISGQGAADIEDSFVFVGGILLKFNTKLMAEIFRIPEEKFRDKVHKSL
CHHHHHHHCCCHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
EENVTWVERETGRLPSYEEVEEFLVEEFSKVIPFEGEEPVPEEAIELADKLKEEFTSEEV
HHCCEEEEHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCE
LLEDTGRKHRAIKLREGVYLRTAVHKAQGGLIRTEVYTDGEVIERVKIYGDFTLYPKESL
EHHCCCCCCCEEEECCCEEHHHHHHHHCCCEEEEEEECCHHHHHHHHEEECEEECCHHHH
KELEEKLKGIKFEPEEIKKVAHEFLQKVDMPGVSAEDLVIAIYGD
HHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECC
>Mature Secondary Structure
MKIYRAGKLDNLRSITLFHAMARLGYEGLIITTPVETYASVGYFDKTQEILDLEKCKKLG
CCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEECCHHHHHHCCCCHHHHHHHHHHHHHHCC
IPVIRREVGGGAVLLHENQVFYQLILKKSRAPFKVIDAYKKFSQPVINVYRRLGVEVEYR
CHHEEHCCCCCEEEEECCHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHCCEEEEE
PINDLVVKRNKKKISGQGAADIEDSFVFVGGILLKFNTKLMAEIFRIPEEKFRDKVHKSL
CHHHHHHHCCCHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
EENVTWVERETGRLPSYEEVEEFLVEEFSKVIPFEGEEPVPEEAIELADKLKEEFTSEEV
HHCCEEEEHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCE
LLEDTGRKHRAIKLREGVYLRTAVHKAQGGLIRTEVYTDGEVIERVKIYGDFTLYPKESL
EHHCCCCCCCEEEECCCEEHHHHHHHHCCCEEEEEEECCHHHHHHHHEEECEEECCHHHH
KELEEKLKGIKFEPEEIKKVAHEFLQKVDMPGVSAEDLVIAIYGD
HHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11029001 [H]