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The map label for this gene is rpoB [H]

Identifier: 15606949

GI number: 15606949

Start: 1361772

End: 1366178

Strand: Direct

Name: rpoB [H]

Synonym: aq_1939

Alternate gene names: 15606949

Gene position: 1361772-1366178 (Clockwise)

Preceding gene: 15606948

Following gene: 15606950

Centisome position: 87.78

GC content: 47.22

Gene sequence:

>4407_bases
ATGGCAAAAATTGCGCTACCCCGTAAGTTTTTCGGCAGAAGGTTTGAAGTCCTTGAACCTCCTTACTTACTCAGCATACC
AAAAAACTCCTTTGAAAACTTCGTCCAGTTAAAGGTAAACCCTTACAAAAGGAAAAACGTAGGTCTTGAACACATATTCA
GGACTTCCTTTCCCTTTAAAGATCCTGACGAAAACTTCATACTCGAATACCTCGGTTATGAAATAGGTGATTGGGAATGT
AATAGATGCGGATACAAACCAAAAGACGACCTTCTGGGAGGATGGGACGTAGACTGTCCCCAGTGCGGAGCAAAGCTCGT
TTACAAGGAAAAGTTCACACCAGAGGAGTGTAAGTTAAAGGGGCTCACTTATTCGGCTCCCCTCAGGGTAATGCTCCAGC
TCAAGGCAAAGACTAAAAACGGCTACAGGGAATTTCCTCCAAAGAAGGTTTACTTCGGTGAAATCCCCCTAATGACCGAA
ACCGGCTCTTTCATCATTAACGGAACGGAAAGGATAATAATCAACCAGCTAATACGTTCCAGCGGTGTCTTCTTTGACGA
GAAGGAAGAAAAACAAAAAGACGCCACTATAACGAGGATTCTTTACAGGGGAAGCATAATTCCCGATAAAGGTTCAAGAG
TTGAGTTTGAACTTTCAGGTGCTACGGACCTCATATCTGCAAGGATAGACAGGAAGAAGCTCAGCGCCACAGCGGTGCTC
AGGGCTTTCGGTCTTGAGACCGCATACGACATTCTCAAGTACTTCTACGAGGACGTAAGGAAGTTCATAGTAAAGGACAA
GTACCTTTACGACGCACAAACGGGAGAGGAGTTTACACCCGAGGATTTAGAACATCATTACATCTTTGCGATAATCAAGT
TCAGAGGAAAACTTGTAGGATTTGCATCTTCCAAGGAAAGGGACTTCATAGAGGAGAGGTACATAGAGGAGTGGGAGGAT
CTCGTAAGACTCCTTGACGACGACAGGATAGAGGTTCTCAGTGTAACGGCGGTACCGAGGGACGTAGTTATAAAAAGTCC
TTATGGAAAGAGCCTGATAGACACCCTAGCAAACGATACCTCGCCCAAAGACGTGGACAAAAGAAGCCCCGTAAAGGTTC
CCGCGGAATACACCCTGAGGGACTACGGATTAATGGAAATGTACAAGAGACTCAGACACATCGAAGCGATCACTATGGAA
ATAGATTCCGTCATAGAAAGGGCGAGGATATTCTTCAACGTATTCTTCAGGGACCTAAAGAGGTATGACCTCTCAAGAGT
CGGTAGGGTAAAGATAAACGCCAAAGTTCACAGGATACCGAAGGTTCTGAAACCTGCGGATGTAGATCTCCTTGACCAGC
TCCCGCCCCTAGCTCTCGCGGAAGACTATGGCGAGTACAAGGCGGGAACGAGGGTTACGAAAGATCTCTTAAAAGAACTC
TTCAAGCAATACAAAGAAATAAAAGTTAAGGACTACACGGAAGACGAAGCGAGGTTTATCCTCCCCATAGACCTCGTGAA
TATCCTGAAGTACCTTATAGACCTCAGACACGGCAGGGTAAAGAAGGACGATATCGCACACCTCGGAAACAGAAGAGTAA
GGTCCGTAGGAGAACTCCTTGAAAATCAAGCGAGACTCGGAATTGCCAAAATGGAAAAGGTCTTCAGGGACCGCTCCGCG
GTTATAAACCCCGAACAGCCGGACCTCAAACCGCAGGATTTCATAAACCCGAGGTACGTCACAACAGCTATAACGGACTT
CCTGAAAACCGGACAGCTCTCTCAGTACCTTGACAACACAAATCCCCTTTCTGAGCTCACCCACAAGAGGAGACTCTCGG
CCCTCGGTCCTGGAGGACTTACGAGGGAAAGTGCAAAATTTGAAATAAGAGACGTTCACCCCTCCCACTACGGAAGGATT
TGTCCCATAGAAACGCCCGAAGGACAGAACATAGGACTGGTTACCTCACCCACAGTTTACGCCAGGGTCAACGAGTACGG
CTTCCTCATAACTCCGTACAGAAAGGTTGAGAACGGGAAGGTAACCGATAAGATTGAGTGGCTTGCGGCTTATGAAGAAG
AAAATTACGTAATAGCCCAGAGCACACCCACCGACGAAGAGGGTAGACTGAAAGCTGAATTTATCCTCGCCAGACACAAG
AACGATATAAGACTCGTAAAACCTGAACAGGTTGAGTACATAGACGTCTCTCCTAGACAGGTAATATCACCCTCTTCTTC
ACTCATACCCTTCCTTGAGCACGACGACGCAAACAGGGCACTCATGGGTTCAAACATGCAAAGGCAGGCGGTTCCCCTCA
TATTCACTCAGGCGCCCCTCATCGGAACGGGAATGGAAAAGAAGATAGCGAGAGATTCCCATGCAGTAGTAGTTGCAAAG
AGGGGCGGTGTGGTAGAGGAAGTTGACAGTTCCAAGATAATCATCAGGGTAAATCCCGAGGAGATAAACTTCGACGACCC
TCTGGACATAGGTATAGACATATACGAACTCAGGAAGTTCCAGAGAACTAACCAGAAGACCTGTGTAAACCAGAGACCCA
TAGTCAGGAAAGGAGAAAAGGTTGAAAAAGGACAAATCATAGCGGACGGACACTCCACTGACAGGGGAGAGCTTGCACTC
GGAAAGGACGTTCTCGTTGCCTTCATGCCCTGGAGAGGTTACAACTTCGAGGACGCAATAGTAATATCCGAGAGACTCGT
CAAGGAAGACGTATACACATCTATCCACATAGAGGAACTGGAAGTAGAAGCGAGAGAAACGAAGGTAGGAGAAGAAGAAA
TAACGAGGCAAATACCTGGAGTTCCTGAAAGAGCACTCGCTCACCTTGATGAGCACGGAATAGTAAGGGTGGGAACTTAC
GTAAAGCCCGGAGACATTCTCGTTGGTAAAGTCACTCCAAAAGGAGAAACGAGGCTAACTCCCGAAGAAAAGCTCCTTCA
GGCAATATTTGGTGAAAAGACAAGGGACGTAAAGGACGCATCCCTCAGGTGTCCTCCCGGAGTTGAGGGAATAGTAATAG
ACGTTCAAGTGTTCACGAGGAAGGGAACCGGCAAAAAGGACATGCTAGCTGAGAAAGTAGAAAGGGAAGAACTAGAAGCA
CTGGAGCAGGAACTTGAAAAGAAGAAGAACCTCATCATCACCGGAAGGGATAAGGTTCTAAAAGGACTTGTACTGGGAAG
GAAGGTAGAAAAAGACGCAAAAGTAGGAAGGAAGACCGTAAAGAAGGGAACAGTTATAGACGAAAAAGTCTTTGAAGAGT
TCGTAAACTACATACTCGGCAGACCCGAAAACTTCTTTGAAGACGAAGACCTTATCAGAAAGATAAGGGAAATAGCGGAA
AGGACGAGAACTCAAATAGAAATGCTCAACAAGGTATACGAAGAGAAAAAGGAAACACTCCTCAAGAGAAGGGATCTCCC
GCCCGGAGTTATAACGCTTGTTAAAGTGTTCATAGCGAACAAGAGGAAGATAAAAGTCGGTGACAAGATGGCGGGAAGGC
ACGGAAACAAGGGTGTTATATCCGTGGTTCTTCCCGTAGAAGACATGCCCTTCCTCCCCGACGGAACGCCCGTTGATATA
GTCCTCAACCCCCTAGGTGTTCCCTCACGTATGAACGTAGGACAAATTCTCGAGACGCACCTCGGCTGGGCTGCAAAAGA
ACTCGGAAAGAAGATAGGCGAGATGATTGAAAAGGGAAGGGACAGGAAGGCTATAACAGAATACCTGAAAGAAATATTCG
CAATAGGAGACAAGGACGGGGAAAACGCCAAGTTCATAGAGGAATTCCTGAATTCCTTATCCGAGGAAGAGTTCTGGAGT
GTGGTCAGGGATTACGCTGAAAGAGGCATTCCTATGGCAACGCCCGCCTTCGAGGGTGCCGAAGAAGATGCAATTAAAGA
ACTCCTCAAGAAAGCGGGGCTGCCCGAAAACGGAAAGACCACCCTTTACGACGGGAGAACAGGAGAGCCCTTTGACTTTG
AGGTTACCGTCGGTTACATGCACATGCTAAAGCTAATCCACATGGTTGACGACAAGATACACGCAAGGGCAACAGGACCT
TACTCCCTCGTTACGCAACAACCCCTCGGTGGTAGGGCGCAGTTTGGTGGACAAAGGCTTGGTGAAATGGAAGTTTGGGC
ACTCGAAGCCCACGGAGCCGCTTACACCTTACAGGAAATGCTCACGGTTAAGTCCGACGACGTTGAAGGAAGGACGAAGG
TTTACGAGGCTATCGTTAAAGGAAAGTACACCTACACACCCGGAATACCCGAGTCCTTCAAGGTTCTCGTAAGAGAGCTA
AAGGCTCTTGGGCTAAACGTTAAGTGTCTGAATGGTGAAGAGAAGCCTTGTGACGAGGTTGAAGTTAAAGAGGAGGAAGA
AAAATGA

Upstream 100 bases:

>100_bases
CAGTGTACTTTTTTGGTTTAAATTTAAAAGATCAGTTAATGGGGATATTATTGCTTCATTCCGCCTTCTTTAAGAAACAT
AAAAGAGGAGAGGTATAAAA

Downstream 100 bases:

>100_bases
GTGAAGCAAGAAGGGGTATCTTCCCCTTCTCAAAAATTAAATTGATGCTCGCTTCTCCCGAGGATATCAGAAGCTGGTCT
CACGGTGAAGTTAAGAGACC

Product: DNA-directed RNA polymerase subunit beta

Products: NA

Alternate protein names: RNAP subunit beta; RNA polymerase subunit beta; Transcriptase subunit beta [H]

Number of amino acids: Translated: 1468; Mature: 1467

Protein sequence:

>1468_residues
MAKIALPRKFFGRRFEVLEPPYLLSIPKNSFENFVQLKVNPYKRKNVGLEHIFRTSFPFKDPDENFILEYLGYEIGDWEC
NRCGYKPKDDLLGGWDVDCPQCGAKLVYKEKFTPEECKLKGLTYSAPLRVMLQLKAKTKNGYREFPPKKVYFGEIPLMTE
TGSFIINGTERIIINQLIRSSGVFFDEKEEKQKDATITRILYRGSIIPDKGSRVEFELSGATDLISARIDRKKLSATAVL
RAFGLETAYDILKYFYEDVRKFIVKDKYLYDAQTGEEFTPEDLEHHYIFAIIKFRGKLVGFASSKERDFIEERYIEEWED
LVRLLDDDRIEVLSVTAVPRDVVIKSPYGKSLIDTLANDTSPKDVDKRSPVKVPAEYTLRDYGLMEMYKRLRHIEAITME
IDSVIERARIFFNVFFRDLKRYDLSRVGRVKINAKVHRIPKVLKPADVDLLDQLPPLALAEDYGEYKAGTRVTKDLLKEL
FKQYKEIKVKDYTEDEARFILPIDLVNILKYLIDLRHGRVKKDDIAHLGNRRVRSVGELLENQARLGIAKMEKVFRDRSA
VINPEQPDLKPQDFINPRYVTTAITDFLKTGQLSQYLDNTNPLSELTHKRRLSALGPGGLTRESAKFEIRDVHPSHYGRI
CPIETPEGQNIGLVTSPTVYARVNEYGFLITPYRKVENGKVTDKIEWLAAYEEENYVIAQSTPTDEEGRLKAEFILARHK
NDIRLVKPEQVEYIDVSPRQVISPSSSLIPFLEHDDANRALMGSNMQRQAVPLIFTQAPLIGTGMEKKIARDSHAVVVAK
RGGVVEEVDSSKIIIRVNPEEINFDDPLDIGIDIYELRKFQRTNQKTCVNQRPIVRKGEKVEKGQIIADGHSTDRGELAL
GKDVLVAFMPWRGYNFEDAIVISERLVKEDVYTSIHIEELEVEARETKVGEEEITRQIPGVPERALAHLDEHGIVRVGTY
VKPGDILVGKVTPKGETRLTPEEKLLQAIFGEKTRDVKDASLRCPPGVEGIVIDVQVFTRKGTGKKDMLAEKVEREELEA
LEQELEKKKNLIITGRDKVLKGLVLGRKVEKDAKVGRKTVKKGTVIDEKVFEEFVNYILGRPENFFEDEDLIRKIREIAE
RTRTQIEMLNKVYEEKKETLLKRRDLPPGVITLVKVFIANKRKIKVGDKMAGRHGNKGVISVVLPVEDMPFLPDGTPVDI
VLNPLGVPSRMNVGQILETHLGWAAKELGKKIGEMIEKGRDRKAITEYLKEIFAIGDKDGENAKFIEEFLNSLSEEEFWS
VVRDYAERGIPMATPAFEGAEEDAIKELLKKAGLPENGKTTLYDGRTGEPFDFEVTVGYMHMLKLIHMVDDKIHARATGP
YSLVTQQPLGGRAQFGGQRLGEMEVWALEAHGAAYTLQEMLTVKSDDVEGRTKVYEAIVKGKYTYTPGIPESFKVLVREL
KALGLNVKCLNGEEKPCDEVEVKEEEEK

Sequences:

>Translated_1468_residues
MAKIALPRKFFGRRFEVLEPPYLLSIPKNSFENFVQLKVNPYKRKNVGLEHIFRTSFPFKDPDENFILEYLGYEIGDWEC
NRCGYKPKDDLLGGWDVDCPQCGAKLVYKEKFTPEECKLKGLTYSAPLRVMLQLKAKTKNGYREFPPKKVYFGEIPLMTE
TGSFIINGTERIIINQLIRSSGVFFDEKEEKQKDATITRILYRGSIIPDKGSRVEFELSGATDLISARIDRKKLSATAVL
RAFGLETAYDILKYFYEDVRKFIVKDKYLYDAQTGEEFTPEDLEHHYIFAIIKFRGKLVGFASSKERDFIEERYIEEWED
LVRLLDDDRIEVLSVTAVPRDVVIKSPYGKSLIDTLANDTSPKDVDKRSPVKVPAEYTLRDYGLMEMYKRLRHIEAITME
IDSVIERARIFFNVFFRDLKRYDLSRVGRVKINAKVHRIPKVLKPADVDLLDQLPPLALAEDYGEYKAGTRVTKDLLKEL
FKQYKEIKVKDYTEDEARFILPIDLVNILKYLIDLRHGRVKKDDIAHLGNRRVRSVGELLENQARLGIAKMEKVFRDRSA
VINPEQPDLKPQDFINPRYVTTAITDFLKTGQLSQYLDNTNPLSELTHKRRLSALGPGGLTRESAKFEIRDVHPSHYGRI
CPIETPEGQNIGLVTSPTVYARVNEYGFLITPYRKVENGKVTDKIEWLAAYEEENYVIAQSTPTDEEGRLKAEFILARHK
NDIRLVKPEQVEYIDVSPRQVISPSSSLIPFLEHDDANRALMGSNMQRQAVPLIFTQAPLIGTGMEKKIARDSHAVVVAK
RGGVVEEVDSSKIIIRVNPEEINFDDPLDIGIDIYELRKFQRTNQKTCVNQRPIVRKGEKVEKGQIIADGHSTDRGELAL
GKDVLVAFMPWRGYNFEDAIVISERLVKEDVYTSIHIEELEVEARETKVGEEEITRQIPGVPERALAHLDEHGIVRVGTY
VKPGDILVGKVTPKGETRLTPEEKLLQAIFGEKTRDVKDASLRCPPGVEGIVIDVQVFTRKGTGKKDMLAEKVEREELEA
LEQELEKKKNLIITGRDKVLKGLVLGRKVEKDAKVGRKTVKKGTVIDEKVFEEFVNYILGRPENFFEDEDLIRKIREIAE
RTRTQIEMLNKVYEEKKETLLKRRDLPPGVITLVKVFIANKRKIKVGDKMAGRHGNKGVISVVLPVEDMPFLPDGTPVDI
VLNPLGVPSRMNVGQILETHLGWAAKELGKKIGEMIEKGRDRKAITEYLKEIFAIGDKDGENAKFIEEFLNSLSEEEFWS
VVRDYAERGIPMATPAFEGAEEDAIKELLKKAGLPENGKTTLYDGRTGEPFDFEVTVGYMHMLKLIHMVDDKIHARATGP
YSLVTQQPLGGRAQFGGQRLGEMEVWALEAHGAAYTLQEMLTVKSDDVEGRTKVYEAIVKGKYTYTPGIPESFKVLVREL
KALGLNVKCLNGEEKPCDEVEVKEEEEK
>Mature_1467_residues
AKIALPRKFFGRRFEVLEPPYLLSIPKNSFENFVQLKVNPYKRKNVGLEHIFRTSFPFKDPDENFILEYLGYEIGDWECN
RCGYKPKDDLLGGWDVDCPQCGAKLVYKEKFTPEECKLKGLTYSAPLRVMLQLKAKTKNGYREFPPKKVYFGEIPLMTET
GSFIINGTERIIINQLIRSSGVFFDEKEEKQKDATITRILYRGSIIPDKGSRVEFELSGATDLISARIDRKKLSATAVLR
AFGLETAYDILKYFYEDVRKFIVKDKYLYDAQTGEEFTPEDLEHHYIFAIIKFRGKLVGFASSKERDFIEERYIEEWEDL
VRLLDDDRIEVLSVTAVPRDVVIKSPYGKSLIDTLANDTSPKDVDKRSPVKVPAEYTLRDYGLMEMYKRLRHIEAITMEI
DSVIERARIFFNVFFRDLKRYDLSRVGRVKINAKVHRIPKVLKPADVDLLDQLPPLALAEDYGEYKAGTRVTKDLLKELF
KQYKEIKVKDYTEDEARFILPIDLVNILKYLIDLRHGRVKKDDIAHLGNRRVRSVGELLENQARLGIAKMEKVFRDRSAV
INPEQPDLKPQDFINPRYVTTAITDFLKTGQLSQYLDNTNPLSELTHKRRLSALGPGGLTRESAKFEIRDVHPSHYGRIC
PIETPEGQNIGLVTSPTVYARVNEYGFLITPYRKVENGKVTDKIEWLAAYEEENYVIAQSTPTDEEGRLKAEFILARHKN
DIRLVKPEQVEYIDVSPRQVISPSSSLIPFLEHDDANRALMGSNMQRQAVPLIFTQAPLIGTGMEKKIARDSHAVVVAKR
GGVVEEVDSSKIIIRVNPEEINFDDPLDIGIDIYELRKFQRTNQKTCVNQRPIVRKGEKVEKGQIIADGHSTDRGELALG
KDVLVAFMPWRGYNFEDAIVISERLVKEDVYTSIHIEELEVEARETKVGEEEITRQIPGVPERALAHLDEHGIVRVGTYV
KPGDILVGKVTPKGETRLTPEEKLLQAIFGEKTRDVKDASLRCPPGVEGIVIDVQVFTRKGTGKKDMLAEKVEREELEAL
EQELEKKKNLIITGRDKVLKGLVLGRKVEKDAKVGRKTVKKGTVIDEKVFEEFVNYILGRPENFFEDEDLIRKIREIAER
TRTQIEMLNKVYEEKKETLLKRRDLPPGVITLVKVFIANKRKIKVGDKMAGRHGNKGVISVVLPVEDMPFLPDGTPVDIV
LNPLGVPSRMNVGQILETHLGWAAKELGKKIGEMIEKGRDRKAITEYLKEIFAIGDKDGENAKFIEEFLNSLSEEEFWSV
VRDYAERGIPMATPAFEGAEEDAIKELLKKAGLPENGKTTLYDGRTGEPFDFEVTVGYMHMLKLIHMVDDKIHARATGPY
SLVTQQPLGGRAQFGGQRLGEMEVWALEAHGAAYTLQEMLTVKSDDVEGRTKVYEAIVKGKYTYTPGIPESFKVLVRELK
ALGLNVKCLNGEEKPCDEVEVKEEEEK

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates [H]

COG id: COG0085

COG function: function code K; DNA-directed RNA polymerase, beta subunit/140 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta chain family [H]

Homologues:

Organism=Homo sapiens, GI238908505, Length=303, Percent_Identity=30.3630363036304, Blast_Score=128, Evalue=4e-29,
Organism=Homo sapiens, GI238908503, Length=303, Percent_Identity=30.3630363036304, Blast_Score=128, Evalue=5e-29,
Organism=Homo sapiens, GI4505941, Length=311, Percent_Identity=29.2604501607717, Blast_Score=124, Evalue=6e-28,
Organism=Homo sapiens, GI33469941, Length=333, Percent_Identity=29.4294294294294, Blast_Score=118, Evalue=5e-26,
Organism=Homo sapiens, GI212286172, Length=333, Percent_Identity=29.4294294294294, Blast_Score=118, Evalue=5e-26,
Organism=Escherichia coli, GI1790419, Length=1472, Percent_Identity=45.7880434782609, Blast_Score=1159, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17552304, Length=309, Percent_Identity=29.7734627831715, Blast_Score=122, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17506623, Length=244, Percent_Identity=33.1967213114754, Blast_Score=118, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI25144348, Length=303, Percent_Identity=30.03300330033, Blast_Score=102, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6324725, Length=313, Percent_Identity=29.073482428115, Blast_Score=129, Evalue=5e-30,
Organism=Saccharomyces cerevisiae, GI6324781, Length=258, Percent_Identity=33.7209302325581, Blast_Score=125, Evalue=4e-29,
Organism=Saccharomyces cerevisiae, GI6325267, Length=246, Percent_Identity=32.9268292682927, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI17136444, Length=254, Percent_Identity=31.8897637795276, Blast_Score=122, Evalue=2e-27,
Organism=Drosophila melanogaster, GI17647877, Length=257, Percent_Identity=31.1284046692607, Blast_Score=103, Evalue=1e-21,
Organism=Drosophila melanogaster, GI17136446, Length=187, Percent_Identity=33.6898395721925, Blast_Score=77, Evalue=1e-13,

Paralogues:

None

Copy number: 4233 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010243
- InterPro:   IPR019462
- InterPro:   IPR015712
- InterPro:   IPR007120
- InterPro:   IPR007121
- InterPro:   IPR007644
- InterPro:   IPR007642
- InterPro:   IPR007645
- InterPro:   IPR007641
- InterPro:   IPR014724 [H]

Pfam domain/function: PF04563 RNA_pol_Rpb2_1; PF04561 RNA_pol_Rpb2_2; PF04565 RNA_pol_Rpb2_3; PF10385 RNA_pol_Rpb2_45; PF00562 RNA_pol_Rpb2_6; PF04560 RNA_pol_Rpb2_7 [H]

EC number: =2.7.7.6 [H]

Molecular weight: Translated: 167390; Mature: 167259

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: PS01166 RNA_POL_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKIALPRKFFGRRFEVLEPPYLLSIPKNSFENFVQLKVNPYKRKNVGLEHIFRTSFPFK
CCCCCCCHHHHCCCCCCCCCCEEEECCCCCCCCEEEEEECCCCCCCCCHHHHHHCCCCCC
DPDENFILEYLGYEIGDWECNRCGYKPKDDLLGGWDVDCPQCGAKLVYKEKFTPEECKLK
CCCHHHHHHHHCCCCCCCCCCCCCCCCCHHCCCCCCCCCHHHCCEEEEECCCCCHHHEEC
GLTYSAPLRVMLQLKAKTKNGYREFPPKKVYFGEIPLMTETGSFIINGTERIIINQLIRS
CCEECCCCEEEEEEEHHCCCCCCCCCCCEEEECCCCEEECCCCEEECCHHHHHHHHHHHH
SGVFFDEKEEKQKDATITRILYRGSIIPDKGSRVEFELSGATDLISARIDRKKLSATAVL
CCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHH
RAFGLETAYDILKYFYEDVRKFIVKDKYLYDAQTGEEFTPEDLEHHYIFAIIKFRGKLVG
HHHCCHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCEEEEEEEEECCCEEE
FASSKERDFIEERYIEEWEDLVRLLDDDRIEVLSVTAVPRDVVIKSPYGKSLIDTLANDT
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCEEEECCCCHHHHHHHHCCC
SPKDVDKRSPVKVPAEYTLRDYGLMEMYKRLRHIEAITMEIDSVIERARIFFNVFFRDLK
CCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RYDLSRVGRVKINAKVHRIPKVLKPADVDLLDQLPPLALAEDYGEYKAGTRVTKDLLKEL
HHHHHHCCEEEEEHHHHHHHHHCCCCCCHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHH
FKQYKEIKVKDYTEDEARFILPIDLVNILKYLIDLRHGRVKKDDIAHLGNRRVRSVGELL
HHHHHCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHH
ENQARLGIAKMEKVFRDRSAVINPEQPDLKPQDFINPRYVTTAITDFLKTGQLSQYLDNT
HHHHHCCHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCHHHHHHHHHHHCCCHHHHHCCC
NPLSELTHKRRLSALGPGGLTRESAKFEIRDVHPSHYGRICPIETPEGQNIGLVTSPTVY
CCHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCEEEECCEEE
ARVNEYGFLITPYRKVENGKVTDKIEWLAAYEEENYVIAQSTPTDEEGRLKAEFILARHK
EEECCCEEEECCHHCCCCCCCCHHHHHHEEECCCCEEEEECCCCCCCCCEEEEEEEEECC
NDIRLVKPEQVEYIDVSPRQVISPSSSLIPFLEHDDANRALMGSNMQRQAVPLIFTQAPL
CCEEEECCCCEEEEECCCHHHCCCCCCCCCEEECCCCCCHHHCCCCCHHCCCEEEECCCC
IGTGMEKKIARDSHAVVVAKRGGVVEEVDSSKIIIRVNPEEINFDDPLDIGIDIYELRKF
CCCCCHHHHCCCCCEEEEEECCCCCEECCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHH
QRTNQKTCVNQRPIVRKGEKVEKGQIIADGHSTDRGELALGKDVLVAFMPWRGYNFEDAI
HHCCHHHHCCCCCCCCCCCCCCCCEEEECCCCCCCCCEEECCCEEEEEECCCCCCCCHHH
VISERLVKEDVYTSIHIEELEVEARETKVGEEEITRQIPGVPERALAHLDEHGIVRVGTY
HHHHHHHHHHHHHEEEHHHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHCCCCCEEEEECE
VKPGDILVGKVTPKGETRLTPEEKLLQAIFGEKTRDVKDASLRCPPGVEGIVIDVQVFTR
ECCCCEEEEEECCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEEEEEEE
KGTGKKDMLAEKVEREELEALEQELEKKKNLIITGRDKVLKGLVLGRKVEKDAKVGRKTV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECHHHHHHHHHHCCHHHHHHHHHHHHH
KKGTVIDEKVFEEFVNYILGRPENFFEDEDLIRKIREIAERTRTQIEMLNKVYEEKKETL
HCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKRRDLPPGVITLVKVFIANKRKIKVGDKMAGRHGNKGVISVVLPVEDMPFLPDGTPVDI
HHHCCCCCHHHHHHHHHHCCCCEEECCCHHCCCCCCCCEEEEEEECCCCCCCCCCCCEEE
VLNPLGVPSRMNVGQILETHLGWAAKELGKKIGEMIEKGRDRKAITEYLKEIFAIGDKDG
EECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCC
ENAKFIEEFLNSLSEEEFWSVVRDYAERGIPMATPAFEGAEEDAIKELLKKAGLPENGKT
CCHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCE
TLYDGRTGEPFDFEVTVGYMHMLKLIHMVDDKIHARATGPYSLVTQQPLGGRAQFGGQRL
EEECCCCCCCEEEEEEHHHHHHHHHHHHHCCHHHCCCCCCCCEEECCCCCCCHHCCCCCC
GEMEVWALEAHGAAYTLQEMLTVKSDDVEGRTKVYEAIVKGKYTYTPGIPESFKVLVREL
CCEEEEEEECCCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCCEEECCCCCHHHHHHHHHH
KALGLNVKCLNGEEKPCDEVEVKEEEEK
HHCCCEEEEECCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AKIALPRKFFGRRFEVLEPPYLLSIPKNSFENFVQLKVNPYKRKNVGLEHIFRTSFPFK
CCCCCCHHHHCCCCCCCCCCEEEECCCCCCCCEEEEEECCCCCCCCCHHHHHHCCCCCC
DPDENFILEYLGYEIGDWECNRCGYKPKDDLLGGWDVDCPQCGAKLVYKEKFTPEECKLK
CCCHHHHHHHHCCCCCCCCCCCCCCCCCHHCCCCCCCCCHHHCCEEEEECCCCCHHHEEC
GLTYSAPLRVMLQLKAKTKNGYREFPPKKVYFGEIPLMTETGSFIINGTERIIINQLIRS
CCEECCCCEEEEEEEHHCCCCCCCCCCCEEEECCCCEEECCCCEEECCHHHHHHHHHHHH
SGVFFDEKEEKQKDATITRILYRGSIIPDKGSRVEFELSGATDLISARIDRKKLSATAVL
CCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHH
RAFGLETAYDILKYFYEDVRKFIVKDKYLYDAQTGEEFTPEDLEHHYIFAIIKFRGKLVG
HHHCCHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCEEEEEEEEECCCEEE
FASSKERDFIEERYIEEWEDLVRLLDDDRIEVLSVTAVPRDVVIKSPYGKSLIDTLANDT
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCEEEECCCCHHHHHHHHCCC
SPKDVDKRSPVKVPAEYTLRDYGLMEMYKRLRHIEAITMEIDSVIERARIFFNVFFRDLK
CCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RYDLSRVGRVKINAKVHRIPKVLKPADVDLLDQLPPLALAEDYGEYKAGTRVTKDLLKEL
HHHHHHCCEEEEEHHHHHHHHHCCCCCCHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHH
FKQYKEIKVKDYTEDEARFILPIDLVNILKYLIDLRHGRVKKDDIAHLGNRRVRSVGELL
HHHHHCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHH
ENQARLGIAKMEKVFRDRSAVINPEQPDLKPQDFINPRYVTTAITDFLKTGQLSQYLDNT
HHHHHCCHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCHHHHHHHHHHHCCCHHHHHCCC
NPLSELTHKRRLSALGPGGLTRESAKFEIRDVHPSHYGRICPIETPEGQNIGLVTSPTVY
CCHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCEEEECCEEE
ARVNEYGFLITPYRKVENGKVTDKIEWLAAYEEENYVIAQSTPTDEEGRLKAEFILARHK
EEECCCEEEECCHHCCCCCCCCHHHHHHEEECCCCEEEEECCCCCCCCCEEEEEEEEECC
NDIRLVKPEQVEYIDVSPRQVISPSSSLIPFLEHDDANRALMGSNMQRQAVPLIFTQAPL
CCEEEECCCCEEEEECCCHHHCCCCCCCCCEEECCCCCCHHHCCCCCHHCCCEEEECCCC
IGTGMEKKIARDSHAVVVAKRGGVVEEVDSSKIIIRVNPEEINFDDPLDIGIDIYELRKF
CCCCCHHHHCCCCCEEEEEECCCCCEECCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHH
QRTNQKTCVNQRPIVRKGEKVEKGQIIADGHSTDRGELALGKDVLVAFMPWRGYNFEDAI
HHCCHHHHCCCCCCCCCCCCCCCCEEEECCCCCCCCCEEECCCEEEEEECCCCCCCCHHH
VISERLVKEDVYTSIHIEELEVEARETKVGEEEITRQIPGVPERALAHLDEHGIVRVGTY
HHHHHHHHHHHHHEEEHHHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHCCCCCEEEEECE
VKPGDILVGKVTPKGETRLTPEEKLLQAIFGEKTRDVKDASLRCPPGVEGIVIDVQVFTR
ECCCCEEEEEECCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEEEEEEE
KGTGKKDMLAEKVEREELEALEQELEKKKNLIITGRDKVLKGLVLGRKVEKDAKVGRKTV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECHHHHHHHHHHCCHHHHHHHHHHHHH
KKGTVIDEKVFEEFVNYILGRPENFFEDEDLIRKIREIAERTRTQIEMLNKVYEEKKETL
HCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKRRDLPPGVITLVKVFIANKRKIKVGDKMAGRHGNKGVISVVLPVEDMPFLPDGTPVDI
HHHCCCCCHHHHHHHHHHCCCCEEECCCHHCCCCCCCCEEEEEEECCCCCCCCCCCCEEE
VLNPLGVPSRMNVGQILETHLGWAAKELGKKIGEMIEKGRDRKAITEYLKEIFAIGDKDG
EECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCC
ENAKFIEEFLNSLSEEEFWSVVRDYAERGIPMATPAFEGAEEDAIKELLKKAGLPENGKT
CCHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCE
TLYDGRTGEPFDFEVTVGYMHMLKLIHMVDDKIHARATGPYSLVTQQPLGGRAQFGGQRL
EEECCCCCCCEEEEEEHHHHHHHHHHHHHCCHHHCCCCCCCCEEECCCCCCCHHCCCCCC
GEMEVWALEAHGAAYTLQEMLTVKSDDVEGRTKVYEAIVKGKYTYTPGIPESFKVLVREL
CCEEEEEEECCCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCCEEECCCCCHHHHHHHHHH
KALGLNVKCLNGEEKPCDEVEVKEEEEK
HHCCCEEEEECCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10198119 [H]