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The map label for this gene is rnhC

Identifier: 15606830

GI number: 15606830

Start: 1245528

End: 1246301

Strand: Direct

Name: rnhC

Synonym: aq_1768

Alternate gene names: 15606830

Gene position: 1245528-1246301 (Clockwise)

Preceding gene: 15606829

Following gene: 15606833

Centisome position: 80.29

GC content: 37.34

Gene sequence:

>774_bases
TTGCCCTCCCTAAAAATTTCCCCTTCAGAAGCTGAAAAGATACAAAACTACCTTGTTTCATCAGGTTTTAGAAAAATTAA
TGCACCATATACGTTATGGGCCCTTGAAGGAAACGGTGTAAAGGTTTATTACTACAAGACTGGAAGTCTTTTAATACAGG
GAAAAAATTCCGAAAAAGTTTTAAAAGAAGTTTTAAATCTACTGGAAAAGAAAAAACTACCGGGGTGTGATGAATCGGGA
AAAGGGGATATTTTCGGTTCCTTAGTTCTTTGCTGTGTTTGCATTCCGGAGGAAAATTACTTAAAAGTATCTTCCCTAAA
TCCGAGGGATACCAAAAGGCTATCGGATAAAAGGGTAGAAAGGCTTTATTTAGCCCTGAAACCCCTCGTGAAGGCTTACT
GCTACGAAATTAAGCCAGAAGAATACAACAAACTCTATAGAAAATTTCGGAACTTAAATAAGATGATGACGCACTTTTAC
AAGCTCCTTATAGAAAGAGTTAAAGAAGAGTGCGGTGTTTCCGAAGTCGTGGTAGACAAGTATCAGCCATCAAACCCTTT
CGGAGAAGACGTGATATTTGAAACGGAGGCTGAGAGAAACTTGGCTGTTGCGGTGGCAAGTATATTCGCGAGGTATAAAT
TTCTCCAATCCTTAAAGGAAGTTGAAAGAGAACTTGGAATAAAAATCCCTAAAGGAACTTCAAAGGAAGTTAAAGAACTC
GCAAAATCGTTAAAAAATCCGGAAAGATTTATAAAGTTAAACTTTAACGTCTAA

Upstream 100 bases:

>100_bases
AGTTATTCATAAAAACGAAGCTGCAAGAAGGGCTTCAAGGGTTTACAAGCTATTAAACAAAGCCCTTCAGCAGCAACAAG
CTCAGGCTTGATCCTTTCCT

Downstream 100 bases:

>100_bases
AAAGTCCACGTAAGAGTCTTCTATGCCTGCCTCTTCGAGCAGATCTTTTAAGTTTACCTTAAATTCATAGCAAAAATCGC
TTTCTTCTAAGCAGGTATAT

Product: hypothetical protein

Products: NA

Alternate protein names: RNase HIII

Number of amino acids: Translated: 257; Mature: 256

Protein sequence:

>257_residues
MPSLKISPSEAEKIQNYLVSSGFRKINAPYTLWALEGNGVKVYYYKTGSLLIQGKNSEKVLKEVLNLLEKKKLPGCDESG
KGDIFGSLVLCCVCIPEENYLKVSSLNPRDTKRLSDKRVERLYLALKPLVKAYCYEIKPEEYNKLYRKFRNLNKMMTHFY
KLLIERVKEECGVSEVVVDKYQPSNPFGEDVIFETEAERNLAVAVASIFARYKFLQSLKEVERELGIKIPKGTSKEVKEL
AKSLKNPERFIKLNFNV

Sequences:

>Translated_257_residues
MPSLKISPSEAEKIQNYLVSSGFRKINAPYTLWALEGNGVKVYYYKTGSLLIQGKNSEKVLKEVLNLLEKKKLPGCDESG
KGDIFGSLVLCCVCIPEENYLKVSSLNPRDTKRLSDKRVERLYLALKPLVKAYCYEIKPEEYNKLYRKFRNLNKMMTHFY
KLLIERVKEECGVSEVVVDKYQPSNPFGEDVIFETEAERNLAVAVASIFARYKFLQSLKEVERELGIKIPKGTSKEVKEL
AKSLKNPERFIKLNFNV
>Mature_256_residues
PSLKISPSEAEKIQNYLVSSGFRKINAPYTLWALEGNGVKVYYYKTGSLLIQGKNSEKVLKEVLNLLEKKKLPGCDESGK
GDIFGSLVLCCVCIPEENYLKVSSLNPRDTKRLSDKRVERLYLALKPLVKAYCYEIKPEEYNKLYRKFRNLNKMMTHFYK
LLIERVKEECGVSEVVVDKYQPSNPFGEDVIFETEAERNLAVAVASIFARYKFLQSLKEVERELGIKIPKGTSKEVKELA
KSLKNPERFIKLNFNV

Specific function: Endonuclease that specifically degrades the RNA of RNA- DNA hybrids

COG id: COG1039

COG function: function code L; Ribonuclease HIII

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase HII family. RnhC subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RNH3_AQUAE (O67644)

Other databases:

- EMBL:   AE000657
- PIR:   B70452
- RefSeq:   NP_214210.1
- ProteinModelPortal:   O67644
- GeneID:   1193359
- GenomeReviews:   AE000657_GR
- KEGG:   aae:aq_1768
- NMPDR:   fig|224324.1.peg.1225
- ProtClustDB:   CLSK2748509
- BioCyc:   AAEO224324:AQ_1768-MONOMER
- BRENDA:   3.1.26.4
- GO:   GO:0005737
- HAMAP:   MF_00053
- InterPro:   IPR001352
- InterPro:   IPR004641
- InterPro:   IPR012337
- PIRSF:   PIRSF037748
- TIGRFAMs:   TIGR00716

Pfam domain/function: PF01351 RNase_HII; SSF53098 RNaseH_fold

EC number: =3.1.26.4

Molecular weight: Translated: 29539; Mature: 29408

Theoretical pI: Translated: 9.62; Mature: 9.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSLKISPSEAEKIQNYLVSSGFRKINAPYTLWALEGNGVKVYYYKTGSLLIQGKNSEKV
CCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCEEEEEEECCEEEEECCCHHHH
LKEVLNLLEKKKLPGCDESGKGDIFGSLVLCCVCIPEENYLKVSSLNPRDTKRLSDKRVE
HHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEECCCCCHHHHHHHHHHHH
RLYLALKPLVKAYCYEIKPEEYNKLYRKFRNLNKMMTHFYKLLIERVKEECGVSEVVVDK
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHC
YQPSNPFGEDVIFETEAERNLAVAVASIFARYKFLQSLKEVERELGIKIPKGTSKEVKEL
CCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
AKSLKNPERFIKLNFNV
HHHHCCCCCEEEEECCC
>Mature Secondary Structure 
PSLKISPSEAEKIQNYLVSSGFRKINAPYTLWALEGNGVKVYYYKTGSLLIQGKNSEKV
CCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCEEEEEEECCEEEEECCCHHHH
LKEVLNLLEKKKLPGCDESGKGDIFGSLVLCCVCIPEENYLKVSSLNPRDTKRLSDKRVE
HHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEECCCCCHHHHHHHHHHHH
RLYLALKPLVKAYCYEIKPEEYNKLYRKFRNLNKMMTHFYKLLIERVKEECGVSEVVVDK
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHC
YQPSNPFGEDVIFETEAERNLAVAVASIFARYKFLQSLKEVERELGIKIPKGTSKEVKEL
CCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
AKSLKNPERFIKLNFNV
HHHHCCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320