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The map label for this gene is dnaB [H]

Identifier: 15606635

GI number: 15606635

Start: 1049037

End: 1050443

Strand: Direct

Name: dnaB [H]

Synonym: aq_1472

Alternate gene names: 15606635

Gene position: 1049037-1050443 (Clockwise)

Preceding gene: 15606634

Following gene: 15606636

Centisome position: 67.62

GC content: 45.34

Gene sequence:

>1407_bases
ATGCAATTTGTGGATAAACTTCCCTGTGACGAATCCGCCGAGAGGGCGGTTCTTGGCAGTATGCTTGAAGACCCCGAAAA
CATACCTCTGGTACTTGAATACCTTAAAGAAGAAGACTTCTGCATAGACGAGCACAAGCTACTTTTCAGGGTTCTTACAA
ACCTCTGGTCCGAGTACGGCAATAAGCTCGATTTCGTATTAATAAAGGATCACCTTGAAAAGAAAAACTTACTCCAGAAA
ATACCTATAGACTGGCTCGAAGAACTCTACGAGGAGGCGGTATCCCCTGACACGCTTGAGGAAGTCTGCAAAATAGTAAA
ACAACGTTCCGCACAGAGGGCGATAATTCAACTCGGTATAGAACTCATTCACAAAGGAAAGGAAAACAAAGACTTTCACA
CATTAATCGAGGAAGCCCAGAGCAGGATATTTTCCATAGCGGAAAGTGCTACATCTACGCAGTTTTACCATGTGAAAGAC
GTTGCGGAAGAAGTTATAGAACTCATTTATAAATTCAAAAGCTCTGACAGGCTAGTCACGGGACTCCCAAGCGGTTTCAC
GGAACTCGATCTAAAGACGACGGGATTCCACCCTGGAGACTTAATAATACTCGCCGCAAGACCCGGTATGGGGAAAACCG
CCTTTATGCTCTCCATAATCTACAATCTCGCAAAAGACGAGGGAAAACCCTCAGCTGTATTTTCCTTGGAAATGAGCAAG
GAACAGCTCGTTATGAGACTCCTCTCTATGATGTCGGAGGTCCCACTTTTCAAGATAAGGTCTGGAAGTATATCGAATGA
AGATTTAAAGAAGCTTGAAGCAAGCGCAATAGAACTCGCAAAGTACGACATATACCTCGACGACACACCCGCTCTCACTA
CAACGGATTTAAGGATAAGGGCAAGAAAGCTCAGAAAGGAAAAGGAAGTTGAGTTCGTGGCGGTGGACTACTTGCAACTT
CTGAGACCGCCAGTCCGAAAGAGTTCAAGACAGGAGGAAGTGGCAGAGGTTTCAAGAAACTTAAAAGCCCTTGCAAAGGA
ACTTCACATTCCCGTTATGGCACTTGCGCAGCTCTCCCGTGAGGTGGAAAAGAGGAGTGATAAAAGACCCCAGCTTGCGG
ACCTCAGAGAATCCGGACAGATAGAACAGGACGCAGACCTAATCCTTTTCCTCCACAGACCCGAGTACTACAAGAAAAAG
CCAAATCCCGAAGAGCAGGGTATAGCGGAAGTGATAATAGCCAAGCAAAGGCAAGGACCCACGGACATTGTGAAGCTCGC
ATTTATTAAGGAGTACACTAAGTTTGCAAACCTAGAAGCCCTTCCTGAACAACCTCCTGAAGAAGAGGAACTTTCCGAAA
TTATTGAAACACAGGAGGATGAAGGATTCGAAGATATTGACTTCTGA

Upstream 100 bases:

>100_bases
CTTAACGCTTCTGGCCACTATATCTTCCTGTTTAAAGTCAAGCATTTCCGCCTCCTTGAAGTTCTCGTAAAAACATTTTA
ACGACTGTAAATTAAATTTA

Downstream 100 bases:

>100_bases
AAATTAAGGTTTTATAATTTTATCTTGGCTATCCGGGGTAGCTCAATCGGCAGAGCGGGTGGCTGTTAACCACCTGGTTG
GGGGTTCGAGTCCCTCCCCC

Product: replicative DNA helicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 468; Mature: 468

Protein sequence:

>468_residues
MQFVDKLPCDESAERAVLGSMLEDPENIPLVLEYLKEEDFCIDEHKLLFRVLTNLWSEYGNKLDFVLIKDHLEKKNLLQK
IPIDWLEELYEEAVSPDTLEEVCKIVKQRSAQRAIIQLGIELIHKGKENKDFHTLIEEAQSRIFSIAESATSTQFYHVKD
VAEEVIELIYKFKSSDRLVTGLPSGFTELDLKTTGFHPGDLIILAARPGMGKTAFMLSIIYNLAKDEGKPSAVFSLEMSK
EQLVMRLLSMMSEVPLFKIRSGSISNEDLKKLEASAIELAKYDIYLDDTPALTTTDLRIRARKLRKEKEVEFVAVDYLQL
LRPPVRKSSRQEEVAEVSRNLKALAKELHIPVMALAQLSREVEKRSDKRPQLADLRESGQIEQDADLILFLHRPEYYKKK
PNPEEQGIAEVIIAKQRQGPTDIVKLAFIKEYTKFANLEALPEQPPEEEELSEIIETQEDEGFEDIDF

Sequences:

>Translated_468_residues
MQFVDKLPCDESAERAVLGSMLEDPENIPLVLEYLKEEDFCIDEHKLLFRVLTNLWSEYGNKLDFVLIKDHLEKKNLLQK
IPIDWLEELYEEAVSPDTLEEVCKIVKQRSAQRAIIQLGIELIHKGKENKDFHTLIEEAQSRIFSIAESATSTQFYHVKD
VAEEVIELIYKFKSSDRLVTGLPSGFTELDLKTTGFHPGDLIILAARPGMGKTAFMLSIIYNLAKDEGKPSAVFSLEMSK
EQLVMRLLSMMSEVPLFKIRSGSISNEDLKKLEASAIELAKYDIYLDDTPALTTTDLRIRARKLRKEKEVEFVAVDYLQL
LRPPVRKSSRQEEVAEVSRNLKALAKELHIPVMALAQLSREVEKRSDKRPQLADLRESGQIEQDADLILFLHRPEYYKKK
PNPEEQGIAEVIIAKQRQGPTDIVKLAFIKEYTKFANLEALPEQPPEEEELSEIIETQEDEGFEDIDF
>Mature_468_residues
MQFVDKLPCDESAERAVLGSMLEDPENIPLVLEYLKEEDFCIDEHKLLFRVLTNLWSEYGNKLDFVLIKDHLEKKNLLQK
IPIDWLEELYEEAVSPDTLEEVCKIVKQRSAQRAIIQLGIELIHKGKENKDFHTLIEEAQSRIFSIAESATSTQFYHVKD
VAEEVIELIYKFKSSDRLVTGLPSGFTELDLKTTGFHPGDLIILAARPGMGKTAFMLSIIYNLAKDEGKPSAVFSLEMSK
EQLVMRLLSMMSEVPLFKIRSGSISNEDLKKLEASAIELAKYDIYLDDTPALTTTDLRIRARKLRKEKEVEFVAVDYLQL
LRPPVRKSSRQEEVAEVSRNLKALAKELHIPVMALAQLSREVEKRSDKRPQLADLRESGQIEQDADLILFLHRPEYYKKK
PNPEEQGIAEVIIAKQRQGPTDIVKLAFIKEYTKFANLEALPEQPPEEEELSEIIETQEDEGFEDIDF

Specific function: Participates In Initiation And Elongation During Chromosome Replication; It Exhibits DNA-Dependent ATPase Activity And Contains Distinct Active Sites For ATP Binding, DNA Binding, And Interaction With DNAc Protein, Primase, And Other Prepriming Proteins.

COG id: COG0305

COG function: function code L; Replicative DNA helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SF4 helicase domain [H]

Homologues:

Organism=Escherichia coli, GI1790486, Length=438, Percent_Identity=39.4977168949772, Blast_Score=306, Evalue=3e-84,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR007692
- InterPro:   IPR007694
- InterPro:   IPR007693
- InterPro:   IPR016136 [H]

Pfam domain/function: PF00772 DnaB; PF03796 DnaB_C [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 53666; Mature: 53666

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQFVDKLPCDESAERAVLGSMLEDPENIPLVLEYLKEEDFCIDEHKLLFRVLTNLWSEYG
CCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHC
NKLDFVLIKDHLEKKNLLQKIPIDWLEELYEEAVSPDTLEEVCKIVKQRSAQRAIIQLGI
CCEEEEEEHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
ELIHKGKENKDFHTLIEEAQSRIFSIAESATSTQFYHVKDVAEEVIELIYKFKSSDRLVT
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHCCCCCEEE
GLPSGFTELDLKTTGFHPGDLIILAARPGMGKTAFMLSIIYNLAKDEGKPSAVFSLEMSK
CCCCCCCEECCEECCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCH
EQLVMRLLSMMSEVPLFKIRSGSISNEDLKKLEASAIELAKYDIYLDDTPALTTTDLRIR
HHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHHHHHHEEEEECCCCCCEEHHHHHH
ARKLRKEKEVEFVAVDYLQLLRPPVRKSSRQEEVAEVSRNLKALAKELHIPVMALAQLSR
HHHHHHHHCCHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
EVEKRSDKRPQLADLRESGQIEQDADLILFLHRPEYYKKKPNPEEQGIAEVIIAKQRQGP
HHHHHCCCCCCHHHHHHCCCCCCCCCEEEEEECCHHHCCCCCCHHHHHHHHHHHHCCCCH
TDIVKLAFIKEYTKFANLEALPEQPPEEEELSEIIETQEDEGFEDIDF
HHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MQFVDKLPCDESAERAVLGSMLEDPENIPLVLEYLKEEDFCIDEHKLLFRVLTNLWSEYG
CCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHC
NKLDFVLIKDHLEKKNLLQKIPIDWLEELYEEAVSPDTLEEVCKIVKQRSAQRAIIQLGI
CCEEEEEEHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
ELIHKGKENKDFHTLIEEAQSRIFSIAESATSTQFYHVKDVAEEVIELIYKFKSSDRLVT
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHCCCCCEEE
GLPSGFTELDLKTTGFHPGDLIILAARPGMGKTAFMLSIIYNLAKDEGKPSAVFSLEMSK
CCCCCCCEECCEECCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCH
EQLVMRLLSMMSEVPLFKIRSGSISNEDLKKLEASAIELAKYDIYLDDTPALTTTDLRIR
HHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHHHHHHEEEEECCCCCCEEHHHHHH
ARKLRKEKEVEFVAVDYLQLLRPPVRKSSRQEEVAEVSRNLKALAKELHIPVMALAQLSR
HHHHHHHHCCHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
EVEKRSDKRPQLADLRESGQIEQDADLILFLHRPEYYKKKPNPEEQGIAEVIIAKQRQGP
HHHHHCCCCCCHHHHHHCCCCCCCCCEEEEEECCHHHCCCCCCHHHHHHHHHHHHCCCCH
TDIVKLAFIKEYTKFANLEALPEQPPEEEELSEIIETQEDEGFEDIDF
HHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 1312531 [H]