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The map label for this gene is valS

Identifier: 15606596

GI number: 15606596

Start: 1006934

End: 1010431

Strand: Direct

Name: valS

Synonym: aq_1413

Alternate gene names: 15606596

Gene position: 1006934-1010431 (Clockwise)

Preceding gene: 15606593

Following gene: 15606600

Centisome position: 64.91

GC content: 46.6

Gene sequence:

>3498_bases
ATGGAGATTAAAGAGTACAACCCGAGGGAAATAGAGGAAAAGTGGAGCAGGTACTGGATAGAGAAGGCACTCTACCACGT
GGAAAAACCCGATAAAAGGAAGAAGTTTTCCGTTGTTATACCTCCGCCAAACGTCACGGGTTCCCTTCACATGGGACACG
CCCTGAACGCAACCCTTCAGGACGTTATCGTGAGATGGCAGAGGATGAGAGGAAGGGAGTGTGTATGGGTTCCCGGGTTT
GACCACGCGGGTATAGCGACCCAGTACGTCGTTGAAAAGCAGCTCGCAAAGGAAGGAAAGAGCAGGCTTGAACTTGGTAG
GGAAGAGTTTTTAAAGAAGGTATGGGAGTGGGTACCAAAGTCCAGAAACGCAATAAGGACACAACTCACAAAACTTGGTG
TCTCCGTTGACTGGAAGAGGGAACGCTTTACCTTGGACGAGGGATTTTCAAGGGCGGTAAGGAAGGCTTTCAGAACACTC
TTTGAAGAGGGTTTAATATACAGAGCGGAATACATAGTAAACTGGTGTCCTAATGATAGAACCGCACTTTCGGACCTTGA
GGTTGAGTACGAAGAAGAAAAGGGAAGTCTCTGGTACATAAAGTACCCCATAGTGGACGAAAACGGAAAGGACACGGGAG
AGTTCATAACCGTTGCAACCACGAGACCCGAAACAATGCTCGGAGACACGGCGGTAGCGGTGAACCCGAATGACGATAGG
TATAAACACCTTGTAGGCAAAAGGGCTAGACTTCCCCTTGTCAACTGGGAAAGGAAGGATCTTAGAGGAAACTCCGTATC
AAACCTCATTCCCATAATAGCGGACGAAAGGGTAAAGATGGACTTCGGAACGGGAGCGGTGAAAATCACCCCCGCCCACG
ACCCTCTGGACTTTGAAATAGGAAAGACCCACGACCTTCCCTTTGTAAGGGTCATAGACGAGACGGGAAGGATGAACGAA
AACGCGGGAGACTTTGCGGGAATGGACCGCTACGAGGCAAGGGAAGCCATAGTCGCAAAACTGAGAGAAGACGAACTCCT
GGAAAAGGAAGAGGAAATCACCCACTCCGTAGGGCACTGTTACAGGTGTAAGACCGTAATAGAACCTATGGTCTCGGTTC
AATGGTTCGTGAAAGTCTCCGACCCCAGAATAAAGGACATTTCCATAAAGGTAGTTGAAGAGGGAATAAAGGAAAGGGAA
GAAAAAGAACTCTTCGTTCAACTCGCACAGGTAGAGGAACTCAGCGTAGTAATTCCTCTGAAGGAGGAAGGAAGGCACAA
GATAGTAGTAGTTCTGGACAAAACAGCCAAGTTTCTTGTCGGAAAGAGAGAAGGAGAGCTCGCATACATATACTACCCCA
AGGGTGATGAGAGGACCCTTGAATTCGCAAAGAGACTCGCGGAAGAGTTCAAAGACTACGAGTTCATGGTCGCGTACGAG
GGACTTCCAAAGATAGTTGTAATGGGAAACGAACAACTGGTAGAGCCTGGAAGCTACCTTTTTGTCTACGACGGTAAGAA
GCTTGACCTTTATAAACTGGAAGGGGAAAAGCCCAAGTTCTTGAAAACCCTCGGAAAGGGAGAGGCGGATTTAGAAGTAA
CCCAGAAGTCAATTCAGATAAAACCCGAAAGGATTAAGAAAGTAGAGGAAAGGGAGAAGAGGGTAAAGTTTATTCCCGAA
CACTGGAAGAAATTCTACCTTGATTGGATGTACAACCTGAAAGACTGGTGTATCTCAAGGCAGATATGGTGGGGCCACAG
GATACCGGTTTGGTATTGCAAGGACTGCGGGAACGTAAACGTCTTCACGGACGACGACTTTGATAGGGCACACGACAAGA
TAATCTTCAACCTTATAGCGGACGGAAAGATAGACCAAGAGTTTACCCCTGAAGAAGTAGAAAAGGTGTTAAAGTCCCCT
CACTTCGTCCACCCCGAGATGACAGTTCTTGACTTTTACAAAAAGTTCGTCTTTCACAGATACTACAACATGGACATAAC
CGCGGATTCCCTCAGACTCCTCTTTACTCAGGACATGAACCCTATGGCCATGCTCACTCCCGGCGTGTCCACGAGGAACA
TTTACAAGTACGACTCCCAGAAAAAGAAGTGGAAGATGGTTCTCAGGTGCAAAAAGTGCGGTTCTGAGAACTTAGAACAG
GAAAGGGACGTTCTTGATACGTGGTTCTCTTCGGCTCTCTGGCCTTTTGGAGTGTTCGGCTGGCCCGAAAGCACGGAGGA
CCTCAAAAACCTCTACCCCACGGACTTGCTTGTCACGGGCTTTGACATAATCTTCTTCTGGGTTGCGAGAATGATTATGA
TGGGAACGCACTTTATGAAGGACATACCCTTTTATGATGTTTACGTTCACGCCCTCGTGAGGGATAAATACGGAAGGAAG
ATGTCTAAAACCATAGGAAACGTAATAGACCCCCTTGACATAATAGAGCGCTACGGAGCGGACGCTCTGAGGTTCACGCT
CGCAATCCTGACCGTTCAGGGAAGGGACATAAAACTCGCGGAGGAGAAGTTTGAAGGATATAAACACTTTGCGAACAAAA
TATGGAACGCCGCAAGGTACGTTTTAATGAACACACCGGAGGACTTCATAGCGCGAATTCCCTACATGGCACCCTTGAAA
CCCGAAGACAAGTGGATAATAACGAAACTCAACGAAACTGCGGAGGAAGTAAACAAAGCCCTTGAAAATTACCAATACTC
TCAGGCGGCTCACGCCATATACGAGTTCTTCTGGAGCGATTACTGCGATTGGTATATAGAGTTCACAAAGGAAAGAATTT
ACAAAAAGGCCCCGGAAGATAACGAAGAGGAAAAGGCAAAGGTGGAAAACGAAAGGACTACCGCACTCTACACCCTTCAC
TACGTTCTGGAAAAAGCCCTCAGAATTCTCCACCCCTTCATGCCCTACATAACCGAGGAACTCTGGCACAAACTCCCGAA
CGCCGAAGGAGAGAGCATATCCTTAGCGGAATTTCCCCAGAAAAACGAAGATGAGATATACGAAGAGGACAAACAGAAGG
TTGAGAGGTTAAAAGAAATAATCTCTGCGATAAGGGCTATCCGTTCGGACCTCCAAATAAAACCGAGCGAAAAGATAAAG
GCTTCCTTTAAAACTGAGAGCGAGTTTTCCAGAAGAGTAATTCAAGAGTTCAAGAACCACATACTCAACCTCGCAAAACT
TGAAAGCTTTGAAGAAGTCTCTCAAAGGCCTCAGAACACCGTGGCCACATTCTCAAAGGACACCGAGATATACGTCCACA
TAGAGGGACACGTGGACCTCGATAAACTTATTCAGTCTTACGAAAAGAAGAGAGAAAAGCTTTTAAAAGAACTTGAAAGG
GTAAACAAGAAACTTTCTAACGAGAACTTCCTGAAGAAAGCTCCCGTGGAAGTTGTTGAGAAAGAAAAGCAGATTAAGGA
AGAACTTGAGAACGACTTAAAGAAAGTTGAGGAAATCCTGAAGGTTCTCCGCTCCTGA

Upstream 100 bases:

>100_bases
AGCTCTTCCTTTTTCTTGAATTCGTGAAAAGGGACCTCAGATATGGCGAAGAGCTCCAGGTGCGTGTGGGCGTCTACGAG
CATAATTTAAAATTTTCTTT

Downstream 100 bases:

>100_bases
TTTTTACTTACTTTTCTGGCAGTCTTCGCATATACCGAAAATCTCAAGCCTGTGGTGAGCGGGCTTGAAGTTGTACTTTT
TGCATATTTCTTCCTGAAGC

Product: valyl-tRNA synthetase

Products: NA

Alternate protein names: Valine--tRNA ligase; ValRS

Number of amino acids: Translated: 1165; Mature: 1165

Protein sequence:

>1165_residues
MEIKEYNPREIEEKWSRYWIEKALYHVEKPDKRKKFSVVIPPPNVTGSLHMGHALNATLQDVIVRWQRMRGRECVWVPGF
DHAGIATQYVVEKQLAKEGKSRLELGREEFLKKVWEWVPKSRNAIRTQLTKLGVSVDWKRERFTLDEGFSRAVRKAFRTL
FEEGLIYRAEYIVNWCPNDRTALSDLEVEYEEEKGSLWYIKYPIVDENGKDTGEFITVATTRPETMLGDTAVAVNPNDDR
YKHLVGKRARLPLVNWERKDLRGNSVSNLIPIIADERVKMDFGTGAVKITPAHDPLDFEIGKTHDLPFVRVIDETGRMNE
NAGDFAGMDRYEAREAIVAKLREDELLEKEEEITHSVGHCYRCKTVIEPMVSVQWFVKVSDPRIKDISIKVVEEGIKERE
EKELFVQLAQVEELSVVIPLKEEGRHKIVVVLDKTAKFLVGKREGELAYIYYPKGDERTLEFAKRLAEEFKDYEFMVAYE
GLPKIVVMGNEQLVEPGSYLFVYDGKKLDLYKLEGEKPKFLKTLGKGEADLEVTQKSIQIKPERIKKVEEREKRVKFIPE
HWKKFYLDWMYNLKDWCISRQIWWGHRIPVWYCKDCGNVNVFTDDDFDRAHDKIIFNLIADGKIDQEFTPEEVEKVLKSP
HFVHPEMTVLDFYKKFVFHRYYNMDITADSLRLLFTQDMNPMAMLTPGVSTRNIYKYDSQKKKWKMVLRCKKCGSENLEQ
ERDVLDTWFSSALWPFGVFGWPESTEDLKNLYPTDLLVTGFDIIFFWVARMIMMGTHFMKDIPFYDVYVHALVRDKYGRK
MSKTIGNVIDPLDIIERYGADALRFTLAILTVQGRDIKLAEEKFEGYKHFANKIWNAARYVLMNTPEDFIARIPYMAPLK
PEDKWIITKLNETAEEVNKALENYQYSQAAHAIYEFFWSDYCDWYIEFTKERIYKKAPEDNEEEKAKVENERTTALYTLH
YVLEKALRILHPFMPYITEELWHKLPNAEGESISLAEFPQKNEDEIYEEDKQKVERLKEIISAIRAIRSDLQIKPSEKIK
ASFKTESEFSRRVIQEFKNHILNLAKLESFEEVSQRPQNTVATFSKDTEIYVHIEGHVDLDKLIQSYEKKREKLLKELER
VNKKLSNENFLKKAPVEVVEKEKQIKEELENDLKKVEEILKVLRS

Sequences:

>Translated_1165_residues
MEIKEYNPREIEEKWSRYWIEKALYHVEKPDKRKKFSVVIPPPNVTGSLHMGHALNATLQDVIVRWQRMRGRECVWVPGF
DHAGIATQYVVEKQLAKEGKSRLELGREEFLKKVWEWVPKSRNAIRTQLTKLGVSVDWKRERFTLDEGFSRAVRKAFRTL
FEEGLIYRAEYIVNWCPNDRTALSDLEVEYEEEKGSLWYIKYPIVDENGKDTGEFITVATTRPETMLGDTAVAVNPNDDR
YKHLVGKRARLPLVNWERKDLRGNSVSNLIPIIADERVKMDFGTGAVKITPAHDPLDFEIGKTHDLPFVRVIDETGRMNE
NAGDFAGMDRYEAREAIVAKLREDELLEKEEEITHSVGHCYRCKTVIEPMVSVQWFVKVSDPRIKDISIKVVEEGIKERE
EKELFVQLAQVEELSVVIPLKEEGRHKIVVVLDKTAKFLVGKREGELAYIYYPKGDERTLEFAKRLAEEFKDYEFMVAYE
GLPKIVVMGNEQLVEPGSYLFVYDGKKLDLYKLEGEKPKFLKTLGKGEADLEVTQKSIQIKPERIKKVEEREKRVKFIPE
HWKKFYLDWMYNLKDWCISRQIWWGHRIPVWYCKDCGNVNVFTDDDFDRAHDKIIFNLIADGKIDQEFTPEEVEKVLKSP
HFVHPEMTVLDFYKKFVFHRYYNMDITADSLRLLFTQDMNPMAMLTPGVSTRNIYKYDSQKKKWKMVLRCKKCGSENLEQ
ERDVLDTWFSSALWPFGVFGWPESTEDLKNLYPTDLLVTGFDIIFFWVARMIMMGTHFMKDIPFYDVYVHALVRDKYGRK
MSKTIGNVIDPLDIIERYGADALRFTLAILTVQGRDIKLAEEKFEGYKHFANKIWNAARYVLMNTPEDFIARIPYMAPLK
PEDKWIITKLNETAEEVNKALENYQYSQAAHAIYEFFWSDYCDWYIEFTKERIYKKAPEDNEEEKAKVENERTTALYTLH
YVLEKALRILHPFMPYITEELWHKLPNAEGESISLAEFPQKNEDEIYEEDKQKVERLKEIISAIRAIRSDLQIKPSEKIK
ASFKTESEFSRRVIQEFKNHILNLAKLESFEEVSQRPQNTVATFSKDTEIYVHIEGHVDLDKLIQSYEKKREKLLKELER
VNKKLSNENFLKKAPVEVVEKEKQIKEELENDLKKVEEILKVLRS
>Mature_1165_residues
MEIKEYNPREIEEKWSRYWIEKALYHVEKPDKRKKFSVVIPPPNVTGSLHMGHALNATLQDVIVRWQRMRGRECVWVPGF
DHAGIATQYVVEKQLAKEGKSRLELGREEFLKKVWEWVPKSRNAIRTQLTKLGVSVDWKRERFTLDEGFSRAVRKAFRTL
FEEGLIYRAEYIVNWCPNDRTALSDLEVEYEEEKGSLWYIKYPIVDENGKDTGEFITVATTRPETMLGDTAVAVNPNDDR
YKHLVGKRARLPLVNWERKDLRGNSVSNLIPIIADERVKMDFGTGAVKITPAHDPLDFEIGKTHDLPFVRVIDETGRMNE
NAGDFAGMDRYEAREAIVAKLREDELLEKEEEITHSVGHCYRCKTVIEPMVSVQWFVKVSDPRIKDISIKVVEEGIKERE
EKELFVQLAQVEELSVVIPLKEEGRHKIVVVLDKTAKFLVGKREGELAYIYYPKGDERTLEFAKRLAEEFKDYEFMVAYE
GLPKIVVMGNEQLVEPGSYLFVYDGKKLDLYKLEGEKPKFLKTLGKGEADLEVTQKSIQIKPERIKKVEEREKRVKFIPE
HWKKFYLDWMYNLKDWCISRQIWWGHRIPVWYCKDCGNVNVFTDDDFDRAHDKIIFNLIADGKIDQEFTPEEVEKVLKSP
HFVHPEMTVLDFYKKFVFHRYYNMDITADSLRLLFTQDMNPMAMLTPGVSTRNIYKYDSQKKKWKMVLRCKKCGSENLEQ
ERDVLDTWFSSALWPFGVFGWPESTEDLKNLYPTDLLVTGFDIIFFWVARMIMMGTHFMKDIPFYDVYVHALVRDKYGRK
MSKTIGNVIDPLDIIERYGADALRFTLAILTVQGRDIKLAEEKFEGYKHFANKIWNAARYVLMNTPEDFIARIPYMAPLK
PEDKWIITKLNETAEEVNKALENYQYSQAAHAIYEFFWSDYCDWYIEFTKERIYKKAPEDNEEEKAKVENERTTALYTLH
YVLEKALRILHPFMPYITEELWHKLPNAEGESISLAEFPQKNEDEIYEEDKQKVERLKEIISAIRAIRSDLQIKPSEKIK
ASFKTESEFSRRVIQEFKNHILNLAKLESFEEVSQRPQNTVATFSKDTEIYVHIEGHVDLDKLIQSYEKKREKLLKELER
VNKKLSNENFLKKAPVEVVEKEKQIKEELENDLKKVEEILKVLRS

Specific function: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a "posttransfer" editing activity that hydrolyzes mischarged Thr-tRNA(Val)

COG id: COG0525

COG function: function code J; Valyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily

Homologues:

Organism=Homo sapiens, GI5454158, Length=401, Percent_Identity=43.640897755611, Blast_Score=318, Evalue=1e-86,
Organism=Homo sapiens, GI268370293, Length=419, Percent_Identity=42.2434367541766, Blast_Score=306, Evalue=5e-83,
Organism=Homo sapiens, GI268370297, Length=419, Percent_Identity=42.2434367541766, Blast_Score=306, Evalue=6e-83,
Organism=Homo sapiens, GI268370295, Length=379, Percent_Identity=44.0633245382586, Blast_Score=290, Evalue=4e-78,
Organism=Homo sapiens, GI46852147, Length=387, Percent_Identity=26.8733850129199, Blast_Score=140, Evalue=7e-33,
Organism=Homo sapiens, GI94721239, Length=412, Percent_Identity=25.2427184466019, Blast_Score=110, Evalue=1e-23,
Organism=Homo sapiens, GI94721241, Length=412, Percent_Identity=25.2427184466019, Blast_Score=110, Evalue=1e-23,
Organism=Homo sapiens, GI7661872, Length=401, Percent_Identity=26.4339152119701, Blast_Score=98, Evalue=4e-20,
Organism=Escherichia coli, GI1790708, Length=468, Percent_Identity=41.6666666666667, Blast_Score=346, Evalue=4e-96,
Organism=Escherichia coli, GI2367096, Length=411, Percent_Identity=25.3041362530414, Blast_Score=142, Evalue=1e-34,
Organism=Escherichia coli, GI1786861, Length=418, Percent_Identity=27.7511961722488, Blast_Score=128, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI17510661, Length=397, Percent_Identity=44.080604534005, Blast_Score=315, Evalue=6e-86,
Organism=Caenorhabditis elegans, GI72001587, Length=374, Percent_Identity=42.2459893048128, Blast_Score=279, Evalue=5e-75,
Organism=Caenorhabditis elegans, GI17541896, Length=334, Percent_Identity=26.0479041916168, Blast_Score=110, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI71980946, Length=405, Percent_Identity=24.1975308641975, Blast_Score=94, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI71997510, Length=211, Percent_Identity=25.5924170616114, Blast_Score=69, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71997517, Length=207, Percent_Identity=25.6038647342995, Blast_Score=68, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6321531, Length=442, Percent_Identity=42.9864253393665, Blast_Score=330, Evalue=6e-91,
Organism=Saccharomyces cerevisiae, GI6325217, Length=416, Percent_Identity=26.9230769230769, Blast_Score=124, Evalue=8e-29,
Organism=Saccharomyces cerevisiae, GI6319395, Length=381, Percent_Identity=24.9343832020997, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI17864482, Length=400, Percent_Identity=44.75, Blast_Score=326, Evalue=6e-89,
Organism=Drosophila melanogaster, GI24653289, Length=400, Percent_Identity=44.75, Blast_Score=326, Evalue=6e-89,
Organism=Drosophila melanogaster, GI21355675, Length=397, Percent_Identity=42.0654911838791, Blast_Score=285, Evalue=2e-76,
Organism=Drosophila melanogaster, GI281366294, Length=412, Percent_Identity=25.2427184466019, Blast_Score=111, Evalue=4e-24,
Organism=Drosophila melanogaster, GI28574730, Length=385, Percent_Identity=24.6753246753247, Blast_Score=97, Evalue=9e-20,
Organism=Drosophila melanogaster, GI24668547, Length=385, Percent_Identity=24.6753246753247, Blast_Score=97, Evalue=9e-20,
Organism=Drosophila melanogaster, GI24668543, Length=385, Percent_Identity=24.6753246753247, Blast_Score=97, Evalue=9e-20,
Organism=Drosophila melanogaster, GI21355409, Length=159, Percent_Identity=28.3018867924528, Blast_Score=78, Evalue=5e-14,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYV_AQUAE (O67411)

Other databases:

- EMBL:   AE000657
- PIR:   A70423
- RefSeq:   NP_213976.1
- ProteinModelPortal:   O67411
- SMR:   O67411
- GeneID:   1192942
- GenomeReviews:   AE000657_GR
- KEGG:   aae:aq_1413
- NMPDR:   fig|224324.1.peg.991
- HOGENOM:   HBG577712
- OMA:   TDQWYVS
- ProtClustDB:   CLSK2748453
- BioCyc:   AAEO224324:AQ_1413-MONOMER
- BRENDA:   6.1.1.9
- GO:   GO:0005737
- HAMAP:   MF_02004
- InterPro:   IPR001412
- InterPro:   IPR002300
- InterPro:   IPR014729
- InterPro:   IPR010978
- InterPro:   IPR009080
- InterPro:   IPR013155
- InterPro:   IPR011321
- InterPro:   IPR019499
- InterPro:   IPR009008
- InterPro:   IPR002303
- Gene3D:   G3DSA:3.40.50.620
- Gene3D:   G3DSA:1.10.287.380
- PANTHER:   PTHR11946:SF5
- PRINTS:   PR00986
- TIGRFAMs:   TIGR00422

Pfam domain/function: PF08264 Anticodon_1; PF00133 tRNA-synt_1; PF10458 Val_tRNA-synt_C; SSF46589 tRNA_binding_arm; SSF47323 tRNAsyn_1a_bind; SSF50677 ValRS_IleRS_edit

EC number: =6.1.1.9

Molecular weight: Translated: 137152; Mature: 137152

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: BINDING 803-803

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIKEYNPREIEEKWSRYWIEKALYHVEKPDKRKKFSVVIPPPNVTGSLHMGHALNATLQ
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCEECCCHHHHHHH
DVIVRWQRMRGRECVWVPGFDHAGIATQYVVEKQLAKEGKSRLELGREEFLKKVWEWVPK
HHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCC
SRNAIRTQLTKLGVSVDWKRERFTLDEGFSRAVRKAFRTLFEEGLIYRAEYIVNWCPNDR
CHHHHHHHHHHHCCCEECCHHHCCHHHHHHHHHHHHHHHHHHCCCEEEEEHHEEECCCCC
TALSDLEVEYEEEKGSLWYIKYPIVDENGKDTGEFITVATTRPETMLGDTAVAVNPNDDR
CCHHHCEEEEECCCCCEEEEEEEEECCCCCCCCCEEEEEECCCCHHCCCEEEEECCCCHH
YKHLVGKRARLPLVNWERKDLRGNSVSNLIPIIADERVKMDFGTGAVKITPAHDPLDFEI
HHHHHCCCCCCCCCCCCHHHCCCCCHHHHHHHEECCEEEEEECCCEEEEECCCCCCCCCC
GKTHDLPFVRVIDETGRMNENAGDFAGMDRYEAREAIVAKLREDELLEKEEEITHSVGHC
CCCCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YRCKTVIEPMVSVQWFVKVSDPRIKDISIKVVEEGIKEREEKELFVQLAQVEELSVVIPL
HHHHHHHHHHHCEEEEEEECCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEE
KEEGRHKIVVVLDKTAKFLVGKREGELAYIYYPKGDERTLEFAKRLAEEFKDYEFMVAYE
CCCCCEEEEEEEECCHHHHEECCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCEEEEEEC
GLPKIVVMGNEQLVEPGSYLFVYDGKKLDLYKLEGEKPKFLKTLGKGEADLEVTQKSIQI
CCCEEEEECCCCEECCCCEEEEECCCEEEEEEECCCCCHHHHHHCCCCCCHHHHHHHHCC
KPERIKKVEEREKRVKFIPEHWKKFYLDWMYNLKDWCISRQIWWGHRIPVWYCKDCGNVN
CHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCEE
VFTDDDFDRAHDKIIFNLIADGKIDQEFTPEEVEKVLKSPHFVHPEMTVLDFYKKFVFHR
EEECCCHHHHHHHEEEEEECCCCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
YYNMDITADSLRLLFTQDMNPMAMLTPGVSTRNIYKYDSQKKKWKMVLRCKKCGSENLEQ
HCCCCCCHHHHHEEEECCCCCCEEECCCCCCCCEEECCCHHHHHHHHHHHHHCCCCCHHH
ERDVLDTWFSSALWPFGVFGWPESTEDLKNLYPTDLLVTGFDIIFFWVARMIMMGTHFMK
HHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
DIPFYDVYVHALVRDKYGRKMSKTIGNVIDPLDIIERYGADALRFTLAILTVQGRDIKLA
HCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHEEECCCCEEHH
EEKFEGYKHFANKIWNAARYVLMNTPEDFIARIPYMAPLKPEDKWIITKLNETAEEVNKA
HHHHHHHHHHHHHHHHHHHEEEECCCHHHHHHCCCCCCCCCCCCEEEEEHHHHHHHHHHH
LENYQYSQAAHAIYEFFWSDYCDWYIEFTKERIYKKAPEDNEEEKAKVENERTTALYTLH
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCHHHHHHHHH
YVLEKALRILHPFMPYITEELWHKLPNAEGESISLAEFPQKNEDEIYEEDKQKVERLKEI
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHCCCCCCHHHHHHHHHHHHHHHHH
ISAIRAIRSDLQIKPSEKIKASFKTESEFSRRVIQEFKNHILNLAKLESFEEVSQRPQNT
HHHHHHHHHCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
VATFSKDTEIYVHIEGHVDLDKLIQSYEKKREKLLKELERVNKKLSNENFLKKAPVEVVE
HHEECCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHH
KEKQIKEELENDLKKVEEILKVLRS
HHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEIKEYNPREIEEKWSRYWIEKALYHVEKPDKRKKFSVVIPPPNVTGSLHMGHALNATLQ
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCEECCCHHHHHHH
DVIVRWQRMRGRECVWVPGFDHAGIATQYVVEKQLAKEGKSRLELGREEFLKKVWEWVPK
HHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCC
SRNAIRTQLTKLGVSVDWKRERFTLDEGFSRAVRKAFRTLFEEGLIYRAEYIVNWCPNDR
CHHHHHHHHHHHCCCEECCHHHCCHHHHHHHHHHHHHHHHHHCCCEEEEEHHEEECCCCC
TALSDLEVEYEEEKGSLWYIKYPIVDENGKDTGEFITVATTRPETMLGDTAVAVNPNDDR
CCHHHCEEEEECCCCCEEEEEEEEECCCCCCCCCEEEEEECCCCHHCCCEEEEECCCCHH
YKHLVGKRARLPLVNWERKDLRGNSVSNLIPIIADERVKMDFGTGAVKITPAHDPLDFEI
HHHHHCCCCCCCCCCCCHHHCCCCCHHHHHHHEECCEEEEEECCCEEEEECCCCCCCCCC
GKTHDLPFVRVIDETGRMNENAGDFAGMDRYEAREAIVAKLREDELLEKEEEITHSVGHC
CCCCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YRCKTVIEPMVSVQWFVKVSDPRIKDISIKVVEEGIKEREEKELFVQLAQVEELSVVIPL
HHHHHHHHHHHCEEEEEEECCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEE
KEEGRHKIVVVLDKTAKFLVGKREGELAYIYYPKGDERTLEFAKRLAEEFKDYEFMVAYE
CCCCCEEEEEEEECCHHHHEECCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCEEEEEEC
GLPKIVVMGNEQLVEPGSYLFVYDGKKLDLYKLEGEKPKFLKTLGKGEADLEVTQKSIQI
CCCEEEEECCCCEECCCCEEEEECCCEEEEEEECCCCCHHHHHHCCCCCCHHHHHHHHCC
KPERIKKVEEREKRVKFIPEHWKKFYLDWMYNLKDWCISRQIWWGHRIPVWYCKDCGNVN
CHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCEE
VFTDDDFDRAHDKIIFNLIADGKIDQEFTPEEVEKVLKSPHFVHPEMTVLDFYKKFVFHR
EEECCCHHHHHHHEEEEEECCCCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
YYNMDITADSLRLLFTQDMNPMAMLTPGVSTRNIYKYDSQKKKWKMVLRCKKCGSENLEQ
HCCCCCCHHHHHEEEECCCCCCEEECCCCCCCCEEECCCHHHHHHHHHHHHHCCCCCHHH
ERDVLDTWFSSALWPFGVFGWPESTEDLKNLYPTDLLVTGFDIIFFWVARMIMMGTHFMK
HHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
DIPFYDVYVHALVRDKYGRKMSKTIGNVIDPLDIIERYGADALRFTLAILTVQGRDIKLA
HCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHEEECCCCEEHH
EEKFEGYKHFANKIWNAARYVLMNTPEDFIARIPYMAPLKPEDKWIITKLNETAEEVNKA
HHHHHHHHHHHHHHHHHHHEEEECCCHHHHHHCCCCCCCCCCCCEEEEEHHHHHHHHHHH
LENYQYSQAAHAIYEFFWSDYCDWYIEFTKERIYKKAPEDNEEEKAKVENERTTALYTLH
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCHHHHHHHHH
YVLEKALRILHPFMPYITEELWHKLPNAEGESISLAEFPQKNEDEIYEEDKQKVERLKEI
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHCCCCCCHHHHHHHHHHHHHHHHH
ISAIRAIRSDLQIKPSEKIKASFKTESEFSRRVIQEFKNHILNLAKLESFEEVSQRPQNT
HHHHHHHHHCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
VATFSKDTEIYVHIEGHVDLDKLIQSYEKKREKLLKELERVNKKLSNENFLKKAPVEVVE
HHEECCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHH
KEKQIKEELENDLKKVEEILKVLRS
HHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9537320