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The map label for this gene is czcB2 [H]

Identifier: 15606534

GI number: 15606534

Start: 945014

End: 946060

Strand: Direct

Name: czcB2 [H]

Synonym: aq_1331

Alternate gene names: 15606534

Gene position: 945014-946060 (Clockwise)

Preceding gene: 15606533

Following gene: 15606535

Centisome position: 60.92

GC content: 39.83

Gene sequence:

>1047_bases
ATGCAAACATTACTGTACATTCTGTTTTTATTATTCCTTTTTTCCTGTTCAAAAACGGAGGAGAAAAAAACTCCCCAAGC
GAGGAAAATACAGGTATCCGTCGTAGAAGTTAAAAGAGAAAAGGTAGTTGTAAGCGTTCCTTTCAAAGGAGTCCTGAAGG
CGGTAAAAGAAGCCGAGCTCTCATCTCAGGAGCCCGGAGTTTTAACAAGACTATACAAAAGGGAAGGGGAGTACGTAAAA
AAGGGAGAAGTGCTTGCACAGGTGGAAAGCAATCTTGCAAAGGAAAGCTACAGGAAAGTTTTAAACCAGTTAAAAGAAGT
TGAAAAGCAAGTAGAACTCCAGAAAAAGATTTACGAAAGGAGAAAGAAACTCTTTGAAAGGGAGTTAATATCTAAGGAAG
AGTACGAAAGGGAAAAGTACAAACTTGAAGAATTAATCCAGCGAAAAAAAGCCCTTGAAAGCGAACTGAAGTACTTTAAA
GAAAAAGTAAGGAGACACTATGTAAGAGCTCCTTTTGATGGATACATTACTGAAAGGTACAAAAACATGGGTGATTACGT
TACTCCCCAGACTCCCGTGTTCAGGCTGATAAACCTTGGAGAGCTTGAATTTTCCTTTAAAGTCCCCGCAAGATACGTTT
CCCTTCTGAAAAAAGGAAAAGAATTAAATGTGGAGCTTGAAAATGGTAAGAATGTAAAGGGAAGAGTTTACTTTATCTCC
GAAAGGGGTGACGAGAACAATCAATTTCTTGTAAAACTTTTAATAAATAACGAAGAAGGAAAGTTAAAGGCAGGAACGTT
CGGGTTTGCGGAGGTACCAGTTAGGGAGGTTTACGCCTTTAAGGTTCCCGAGGACGCTGTTATCCTTCAAGGGAACAAAA
AAATAATCTGGGTCCTTGAAGGGAACAGGGTAAGGTCAAGGGAGGTCGAAGTAATATTCATAAATGGTGGATACGCCTAC
GTTGAAGGAGACCTGAAAGACGGCGATAAAGTGGTTACGGAAAACACATTTTTATTGAAAGAAGGAGCTGAGGTAGTGGT
GAGATGA

Upstream 100 bases:

>100_bases
ACAGGTTTCTGGACATGCTGAGAACTGCGGTAAACGTCTGGGGTGACCTGAACGGAGCTAAGATTCTGAATAGGTACGTA
AACAGCTAAAATTAAGAGGT

Downstream 100 bases:

>100_bases
GTGGTGAGATGAGAGTAATTTGGGTAATCCTTTTCCTTTTTACTTTTTCCTTCCCGCTTACCTTGGAAGAAGCGGTAAGT
ATAGCCTTGAAAAACGTAAC

Product: cation efflux system (czcB-like)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 348; Mature: 348

Protein sequence:

>348_residues
MQTLLYILFLLFLFSCSKTEEKKTPQARKIQVSVVEVKREKVVVSVPFKGVLKAVKEAELSSQEPGVLTRLYKREGEYVK
KGEVLAQVESNLAKESYRKVLNQLKEVEKQVELQKKIYERRKKLFERELISKEEYEREKYKLEELIQRKKALESELKYFK
EKVRRHYVRAPFDGYITERYKNMGDYVTPQTPVFRLINLGELEFSFKVPARYVSLLKKGKELNVELENGKNVKGRVYFIS
ERGDENNQFLVKLLINNEEGKLKAGTFGFAEVPVREVYAFKVPEDAVILQGNKKIIWVLEGNRVRSREVEVIFINGGYAY
VEGDLKDGDKVVTENTFLLKEGAEVVVR

Sequences:

>Translated_348_residues
MQTLLYILFLLFLFSCSKTEEKKTPQARKIQVSVVEVKREKVVVSVPFKGVLKAVKEAELSSQEPGVLTRLYKREGEYVK
KGEVLAQVESNLAKESYRKVLNQLKEVEKQVELQKKIYERRKKLFERELISKEEYEREKYKLEELIQRKKALESELKYFK
EKVRRHYVRAPFDGYITERYKNMGDYVTPQTPVFRLINLGELEFSFKVPARYVSLLKKGKELNVELENGKNVKGRVYFIS
ERGDENNQFLVKLLINNEEGKLKAGTFGFAEVPVREVYAFKVPEDAVILQGNKKIIWVLEGNRVRSREVEVIFINGGYAY
VEGDLKDGDKVVTENTFLLKEGAEVVVR
>Mature_348_residues
MQTLLYILFLLFLFSCSKTEEKKTPQARKIQVSVVEVKREKVVVSVPFKGVLKAVKEAELSSQEPGVLTRLYKREGEYVK
KGEVLAQVESNLAKESYRKVLNQLKEVEKQVELQKKIYERRKKLFERELISKEEYEREKYKLEELIQRKKALESELKYFK
EKVRRHYVRAPFDGYITERYKNMGDYVTPQTPVFRLINLGELEFSFKVPARYVSLLKKGKELNVELENGKNVKGRVYFIS
ERGDENNQFLVKLLINNEEGKLKAGTFGFAEVPVREVYAFKVPEDAVILQGNKKIIWVLEGNRVRSREVEVIFINGGYAY
VEGDLKDGDKVVTENTFLLKEGAEVVVR

Specific function: Component of the NCC cation efflux system that confers resistance to nickel, cobalt and cadmium [H]

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=311, Percent_Identity=23.7942122186495, Blast_Score=72, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005695
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 40571; Mature: 40571

Theoretical pI: Translated: 9.88; Mature: 9.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTLLYILFLLFLFSCSKTEEKKTPQARKIQVSVVEVKREKVVVSVPFKGVLKAVKEAEL
CHHHHHHHHHHHHHCCCCCHHHCCCCHHEEEEEEEEEEECEEEEECCHHHHHHHHHHHHC
SSQEPGVLTRLYKREGEYVKKGEVLAQVESNLAKESYRKVLNQLKEVEKQVELQKKIYER
CCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RKKLFERELISKEEYEREKYKLEELIQRKKALESELKYFKEKVRRHYVRAPFDGYITERY
HHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
KNMGDYVTPQTPVFRLINLGELEFSFKVPARYVSLLKKGKELNVELENGKNVKGRVYFIS
HCCCCCCCCCCHHHHHEECCCEEEEEECHHHHHHHHHCCCEEEEEECCCCCCEEEEEEEE
ERGDENNQFLVKLLINNEEGKLKAGTFGFAEVPVREVYAFKVPEDAVILQGNKKIIWVLE
CCCCCCCEEEEEEEEECCCCCEEECCCCCCCCCHHHEEEEECCCCEEEEECCCEEEEEEE
GNRVRSREVEVIFINGGYAYVEGDLKDGDKVVTENTFLLKEGAEVVVR
CCEEECCEEEEEEEECCEEEEECCCCCCCEEEECCEEEEECCCCEECC
>Mature Secondary Structure
MQTLLYILFLLFLFSCSKTEEKKTPQARKIQVSVVEVKREKVVVSVPFKGVLKAVKEAEL
CHHHHHHHHHHHHHCCCCCHHHCCCCHHEEEEEEEEEEECEEEEECCHHHHHHHHHHHHC
SSQEPGVLTRLYKREGEYVKKGEVLAQVESNLAKESYRKVLNQLKEVEKQVELQKKIYER
CCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RKKLFERELISKEEYEREKYKLEELIQRKKALESELKYFKEKVRRHYVRAPFDGYITERY
HHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
KNMGDYVTPQTPVFRLINLGELEFSFKVPARYVSLLKKGKELNVELENGKNVKGRVYFIS
HCCCCCCCCCCHHHHHEECCCEEEEEECHHHHHHHHHCCCEEEEEECCCCCCEEEEEEEE
ERGDENNQFLVKLLINNEEGKLKAGTFGFAEVPVREVYAFKVPEDAVILQGNKKIIWVLE
CCCCCCCEEEEEEEEECCCCCEEECCCCCCCCCHHHEEEEECCCCEEEEECCCEEEEEEE
GNRVRSREVEVIFINGGYAYVEGDLKDGDKVVTENTFLLKEGAEVVVR
CCEEECCEEEEEEEECCEEEEECCCCCCCEEEECCEEEEECCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7961470 [H]