Click here to switch to the map view.

The map label for this gene is sucC1 [H]

Identifier: 15606514

GI number: 15606514

Start: 924687

End: 925997

Strand: Direct

Name: sucC1 [H]

Synonym: aq_1306

Alternate gene names: 15606514

Gene position: 924687-925997 (Clockwise)

Preceding gene: 15606510

Following gene: 15606515

Centisome position: 59.61

GC content: 47.44

Gene sequence:

>1311_bases
ATGGATCTGTACGAGTACGAAGCGTACGATAAAATTTTCAAAAAGTACGGTATTCCCACCCCGAAGTATATGTTCGTTGA
ACACATTACAGATGATGTTGTTGAATTCGTAAATCAACTGGGTGAGTGCGTTGTAAAGTCACAGGTTCTAGTAGGAAAGA
GGGGAAAAGCCGGAGCTGTAAGGGTATGCTCCAATCCCGATGAAGCTTTAGAAGAGATTGAAACACTCCTCAGGATGACT
GTTTACGGAGAAATGCCTGTTGGCGTTCTCGTAGTGGAAAAGGCAAACATCCTGAAAGAACTTTACGCTTCAATAGTTTA
CTCCACGGACCACAGGGCACCCGTACTTACCCTCAGCTTGGAAGGCGGAATGGATATAGAAGAAGTTCCCCCTGATAAGG
TAAAGTCCTGGCCAATAAACCCGCTAAAAGGACTCTACCCCCACATGGTGAGGAATTACCTCCTTGAACTTGGATTTCCC
CACGAATATATGCCCGTTCTCAGGAAGCTCTCAGAAGTTATAGCAAGAATGTGGGACGCCTTCTGGGGGGCTGAAGCGAG
ACTCCTTGAAATCAACCCCCTTGCTATTGTGGACAGGGGCGGAAAGCCTGACGTTCTTGCCCTTGACGCGGTTGTTAAAA
TAGACGACGACGCATCAATACCGCCTGCAAAGATATACGGAGTGAGAACCGCACTCAGGAGACCTCCCACAGAAAGAGAA
ATCGCAGCCGCGGAAATAGACAAGGACGACCACAGAGGAAAGGCAGGCTCTTACGTAGAACTCGACGGTGACATAGCTAT
GATGACCTTCGGAGGAGGAGGTTCTACCGTTACGATAGAAACGTGTTACGAACTCGGACTAAAACCCGCAAACCTCACGG
ACATAGGCGGTAACCCGCCCGCCGAAAAGATGTACAAGATAACGAGGATAATACTCTCCAAACCCGGAATAAGGGCTGTT
CTAATCGCCGGAGGTACTGCAAACAACACGAGAATCGACGTTACTCTCGGTGAAGGTGTTGCAAACGCATTAAGAGACCT
AAAGAAAGAAGGAAAACTCGACCCCAACTGGATATTCGTGGTAAGGAGAAACGGGCCGGAAGCTGAAAAAGGACTCAGAA
TGCTTTACGAGGCCTTTAAAGAGTGTGGAATAAAGGGAGAAATTTACGACTCCGCATTGCCGCTTACCGAAGCTCCCGTG
AGGCTTAAAGAACTCCTCGATAAGTGCCAAGCAAAAAAACTTGAAGAAGAAGAACAAATTAAGGAAGGACATACATTTAC
GGACGAGCAAGCTTCTGACCTCGGAATGTAA

Upstream 100 bases:

>100_bases
TTCAAGTACCTCTGCGTTTAATTCTGCGAGCATACTTGATTTATTTTAATTAAAATACAATAAAATGTTGTTTTAAAATT
AAGTTTCAGGAGGAAGGAGA

Downstream 100 bases:

>100_bases
TTCTCCTTCCCTCCCCTTTTAAAATCTTCTTTTATGTTTAAATTCCACCTGATTACTAAAGACGGAAAAGCGAGAAGAGG
TAGGATATACACCCCTCACG

Product: succinyl-CoA ligase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta [H]

Number of amino acids: Translated: 436; Mature: 436

Protein sequence:

>436_residues
MDLYEYEAYDKIFKKYGIPTPKYMFVEHITDDVVEFVNQLGECVVKSQVLVGKRGKAGAVRVCSNPDEALEEIETLLRMT
VYGEMPVGVLVVEKANILKELYASIVYSTDHRAPVLTLSLEGGMDIEEVPPDKVKSWPINPLKGLYPHMVRNYLLELGFP
HEYMPVLRKLSEVIARMWDAFWGAEARLLEINPLAIVDRGGKPDVLALDAVVKIDDDASIPPAKIYGVRTALRRPPTERE
IAAAEIDKDDHRGKAGSYVELDGDIAMMTFGGGGSTVTIETCYELGLKPANLTDIGGNPPAEKMYKITRIILSKPGIRAV
LIAGGTANNTRIDVTLGEGVANALRDLKKEGKLDPNWIFVVRRNGPEAEKGLRMLYEAFKECGIKGEIYDSALPLTEAPV
RLKELLDKCQAKKLEEEEQIKEGHTFTDEQASDLGM

Sequences:

>Translated_436_residues
MDLYEYEAYDKIFKKYGIPTPKYMFVEHITDDVVEFVNQLGECVVKSQVLVGKRGKAGAVRVCSNPDEALEEIETLLRMT
VYGEMPVGVLVVEKANILKELYASIVYSTDHRAPVLTLSLEGGMDIEEVPPDKVKSWPINPLKGLYPHMVRNYLLELGFP
HEYMPVLRKLSEVIARMWDAFWGAEARLLEINPLAIVDRGGKPDVLALDAVVKIDDDASIPPAKIYGVRTALRRPPTERE
IAAAEIDKDDHRGKAGSYVELDGDIAMMTFGGGGSTVTIETCYELGLKPANLTDIGGNPPAEKMYKITRIILSKPGIRAV
LIAGGTANNTRIDVTLGEGVANALRDLKKEGKLDPNWIFVVRRNGPEAEKGLRMLYEAFKECGIKGEIYDSALPLTEAPV
RLKELLDKCQAKKLEEEEQIKEGHTFTDEQASDLGM
>Mature_436_residues
MDLYEYEAYDKIFKKYGIPTPKYMFVEHITDDVVEFVNQLGECVVKSQVLVGKRGKAGAVRVCSNPDEALEEIETLLRMT
VYGEMPVGVLVVEKANILKELYASIVYSTDHRAPVLTLSLEGGMDIEEVPPDKVKSWPINPLKGLYPHMVRNYLLELGFP
HEYMPVLRKLSEVIARMWDAFWGAEARLLEINPLAIVDRGGKPDVLALDAVVKIDDDASIPPAKIYGVRTALRRPPTERE
IAAAEIDKDDHRGKAGSYVELDGDIAMMTFGGGGSTVTIETCYELGLKPANLTDIGGNPPAEKMYKITRIILSKPGIRAV
LIAGGTANNTRIDVTLGEGVANALRDLKKEGKLDPNWIFVVRRNGPEAEKGLRMLYEAFKECGIKGEIYDSALPLTEAPV
RLKELLDKCQAKKLEEEEQIKEGHTFTDEQASDLGM

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

Organism=Homo sapiens, GI157779135, Length=419, Percent_Identity=25.2983293556086, Blast_Score=115, Evalue=7e-26,
Organism=Homo sapiens, GI294862256, Length=369, Percent_Identity=25.7452574525745, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI11321583, Length=369, Percent_Identity=25.7452574525745, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI38569421, Length=378, Percent_Identity=28.3068783068783, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI38569423, Length=378, Percent_Identity=28.3068783068783, Blast_Score=84, Evalue=4e-16,
Organism=Escherichia coli, GI1786948, Length=334, Percent_Identity=30.2395209580838, Blast_Score=128, Evalue=7e-31,
Organism=Caenorhabditis elegans, GI17567829, Length=389, Percent_Identity=28.0205655526992, Blast_Score=120, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17539378, Length=408, Percent_Identity=26.7156862745098, Blast_Score=118, Evalue=7e-27,
Organism=Caenorhabditis elegans, GI17557344, Length=412, Percent_Identity=27.1844660194175, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17551266, Length=411, Percent_Identity=24.330900243309, Blast_Score=66, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6321683, Length=425, Percent_Identity=25.8823529411765, Blast_Score=119, Evalue=1e-27,
Organism=Drosophila melanogaster, GI21356231, Length=398, Percent_Identity=28.1407035175879, Blast_Score=126, Evalue=2e-29,
Organism=Drosophila melanogaster, GI161078106, Length=396, Percent_Identity=28.2828282828283, Blast_Score=118, Evalue=7e-27,
Organism=Drosophila melanogaster, GI24645208, Length=396, Percent_Identity=28.2828282828283, Blast_Score=118, Evalue=7e-27,
Organism=Drosophila melanogaster, GI281361397, Length=396, Percent_Identity=28.2828282828283, Blast_Score=118, Evalue=9e-27,
Organism=Drosophila melanogaster, GI281361395, Length=396, Percent_Identity=28.2828282828283, Blast_Score=118, Evalue=9e-27,
Organism=Drosophila melanogaster, GI281363477, Length=372, Percent_Identity=25, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI281363475, Length=372, Percent_Identity=25, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI281363473, Length=372, Percent_Identity=25, Blast_Score=74, Evalue=3e-13,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102 [H]

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 48349; Mature: 48349

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLYEYEAYDKIFKKYGIPTPKYMFVEHITDDVVEFVNQLGECVVKSQVLVGKRGKAGAV
CCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEE
RVCSNPDEALEEIETLLRMTVYGEMPVGVLVVEKANILKELYASIVYSTDHRAPVLTLSL
EEECCHHHHHHHHHHHHHHHHCCCCCCCEEEECHHHHHHHHHHHHHHCCCCCCEEEEEEE
EGGMDIEEVPPDKVKSWPINPLKGLYPHMVRNYLLELGFPHEYMPVLRKLSEVIARMWDA
CCCCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
FWGAEARLLEINPLAIVDRGGKPDVLALDAVVKIDDDASIPPAKIYGVRTALRRPPTERE
HCCCCEEEEEECCEEEEECCCCCCEEEEEEEEEECCCCCCCCHHHHHHHHHHHCCCCHHH
IAAAEIDKDDHRGKAGSYVELDGDIAMMTFGGGGSTVTIETCYELGLKPANLTDIGGNPP
HHHHHCCCCCCCCCCCCEEEECCCEEEEEECCCCCEEEEEEHHHCCCCCCCCCCCCCCCC
AEKMYKITRIILSKPGIRAVLIAGGTANNTRIDVTLGEGVANALRDLKKEGKLDPNWIFV
HHHHHHHHHHHHCCCCCEEEEEECCCCCCCEEEEEECHHHHHHHHHHHHHCCCCCCEEEE
VRRNGPEAEKGLRMLYEAFKECGIKGEIYDSALPLTEAPVRLKELLDKCQAKKLEEEEQI
EECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHH
KEGHTFTDEQASDLGM
HCCCCCCCCCHHHCCC
>Mature Secondary Structure
MDLYEYEAYDKIFKKYGIPTPKYMFVEHITDDVVEFVNQLGECVVKSQVLVGKRGKAGAV
CCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEE
RVCSNPDEALEEIETLLRMTVYGEMPVGVLVVEKANILKELYASIVYSTDHRAPVLTLSL
EEECCHHHHHHHHHHHHHHHHCCCCCCCEEEECHHHHHHHHHHHHHHCCCCCCEEEEEEE
EGGMDIEEVPPDKVKSWPINPLKGLYPHMVRNYLLELGFPHEYMPVLRKLSEVIARMWDA
CCCCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
FWGAEARLLEINPLAIVDRGGKPDVLALDAVVKIDDDASIPPAKIYGVRTALRRPPTERE
HCCCCEEEEEECCEEEEECCCCCCEEEEEEEEEECCCCCCCCHHHHHHHHHHHCCCCHHH
IAAAEIDKDDHRGKAGSYVELDGDIAMMTFGGGGSTVTIETCYELGLKPANLTDIGGNPP
HHHHHCCCCCCCCCCCCEEEECCCEEEEEECCCCCEEEEEEHHHCCCCCCCCCCCCCCCC
AEKMYKITRIILSKPGIRAVLIAGGTANNTRIDVTLGEGVANALRDLKKEGKLDPNWIFV
HHHHHHHHHHHHCCCCCEEEEEECCCCCCCEEEEEECHHHHHHHHHHHHHCCCCCCEEEE
VRRNGPEAEKGLRMLYEAFKECGIKGEIYDSALPLTEAPVRLKELLDKCQAKKLEEEEQI
EECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHH
KEGHTFTDEQASDLGM
HCCCCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]