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The map label for this gene is clpC [H]

Identifier: 15606509

GI number: 15606509

Start: 918003

End: 920435

Strand: Direct

Name: clpC [H]

Synonym: aq_1296

Alternate gene names: 15606509

Gene position: 918003-920435 (Clockwise)

Preceding gene: 15606508

Following gene: 15606510

Centisome position: 59.18

GC content: 47.64

Gene sequence:

>2433_bases
ATGTTTGAGAAGTTCACAGAAAGGGCAAGACAAGTTATCTTGAGGGCGAGGGAAGAAGCCCTCGAGCTGGGACACAGCTA
CTTGGGAAGTGAACATATTTTGCTTGCTCTGATAAAGGATGAGGACATACCCGTCCTCGTCCTCAGCAAGCTGGGTGTCT
CTCCTGAGAAGATAAGAAAGGCCATAATGGGCCAAATAACTAAGGGAAGCCACTCGGGAGAGGTACTCTTCGCACCCGAC
GCAAAAAGGGTAATAGAGTTTGCAGTTGAAGAAGCGAGAATTCTTCACCACCAGTTCGTAGGTCCCGAACACCTACTTAT
CGGAGTGGTTAGAGAAAAGACGGGACTCGGTGGAAGAATTTTAAGGAGCTTTGGACTGGACGAGTACTCCGTAAGGAGAG
AGGTACTTCAACTACTCGGAGAACTTCCCCCTCAAGAAAGCCAGAGGTACGTATCCACTCCTAACCTTGACAGGTTCTCA
AGGGACCTCACCCAAATGGCAAGGGAAGGAAAGCTCGACCCAGTAATAGGCAGGGAAAAGGAAATAGAGAGAGTTATCCA
GATACTCGTAAGAAGAAGGAAGAACAACCCTGTCTTGCTCGGAGACCCCGGAGTTGGTAAGACGGCGATAGTAGAAGGGC
TGGCTCAAAGGATAGCAAATAAGGAAGTTCCCGAACCGCTACTCAATAAGAGGGTAGTGGCTTTAGACCTTGCGGCACTA
GTTGCGGGAACCAAGTACAGAGGACAGTTCGAAGAAAGGCTTAAGAACATCTTAAAAGAACTTGAGAAGGCTAACAACGT
AATACTCTTCATAGACGAACTTCACACACTCGTTGGAGCGGGTTCTGCGGAAGGCTCGATAGACGCATCCAATATGCTAA
AACCCGCCCTCGCGAGAGGTGAAATTCAGGTAATAGGAGCTACCACCGTAGACGAGTACAGGAAGTACATAGAAAAGGAC
GGAGCACTGGAGAGAAGGTTCCAGCCCGTTTACGTAGAACAGCCATCACCCGAGGATACGATCCAGATACTTTACGGACT
CAAACCCAAGTTTGAAGAGTTCCACAAGGTAGAGTACACACCCGAGGCAATAGAAAAGGCTGTGGAACTCTCCGTCAAGT
ACATAACCGACAGAAACCTGCCAGATAAGGCTATAGACGTTATGGACGAGGCGGGAGCACTCGTAAAGCTGAAGGCAACT
CAACTCCCTCCTGAACTCAAGGAGATAGAGGAAAAGATTAAGGAACTCGAGAAGGAAAAGGAAAAGGCTGTAAAGGAACA
GGACTACGAGAAGGCTGCAAAGATAAGGGACGAAGAGTTGAGACTCAGGGCTAAGTTCGAAACGATGAAGGCTAAGTGGA
AGGAAGAAATGGAAAAGAACAGACCCAAAGTTACGGACGAGGACGTTGCAGAAGTAGTCGCAAGGTGGACGGGCGTTCCC
GTGAAGAGGGTACACGAAAGTGATGCGGAGAAACTCCTCCACATAGAAGAAGAATTGAAGAAGAGGGTTGTAGGTCAGGA
CGAGGCTATAAAGGCAGTAGCGAAGGCGATAAGACGTTCAAGAGTCGGACTGAAAGGAAAACACAGACCCATAGGCGTAT
TCATGTTCCTAGGACCTACTGGTGTGGGTAAGACCGAAACCGCGAAGGCACTTGCGGAATACCTATTCGGAACGGAAGAC
GCACTCATCAGGTTTGATATGTCCGAGTACATGGAAAAGCACACCGTTTCAAGACTAATCGGTGCACCTCCCGGATACGT
TGGATACGAAGAAGGTGGACAGCTCACAGAGGCGGTAAGGAGAAGACCTTACAGCGTTCTCCTATTTGACGAAATAGAGA
AGGCCCACCCAGACGTATTCAACATCTTCCTCCAGATATTCGACGACGGAAGACTAACGGACGGACTCGGAAGGACCGTT
GACTTCTCCAACACCATAATAATCATGACCTCAAACCTCGGAGCTAGACTCATCACAGGCGGAACGATGGGATTCGAAAA
GAAACAGGGACTCCTTAACTTCGAAGAGATGAGGAAAAACGTCCTTGATCAGGTAAAGAGAACCTTCAGCCCTGAATTCC
TAAACAGACTGGACGAAATTATAGTGTTCAGGCCTCTCGAGAAGAAAGACATAGAACAGATACTCGAACTACAACTAAAA
GAGATAAACGAAAAACTAAAAGACTGGAACGTGAGAGTAAAACTCCACAAGTCCTTCGTAAACTGGATCATAGAAAAAGA
GTACAAGCCCGAATTCGGAGCAAGGAGCTTGAAGAGGGCTCTCCAAAGACACGTTGAAGATCTGCTCGCTGAAGAACTCA
TAAAGGGAACGCTCAAAGGCGTAGAAGAAGTAGAAATAAGGGTAAGGAACGACAAGCCCTACCTCAAACCCGTAAAGAAG
AAGGAAAAAGTAGAAGCCCTTCTCGAAAAGTAA

Upstream 100 bases:

>100_bases
TTAAAAAGACATTATAAAGATATATAACACTGTTTTTGTCATAGCCTTGAAAAAGCTTAGGTTTTTTTTATTTTATAAAA
AACTGAGAGAGGTAAGAGAC

Downstream 100 bases:

>100_bases
GCCCCTTTTTCCTTCTTTCCTTTATAATACTTTCCTTGTGAAAAAGGAATTTTTAACCCTAGCCCTTTTTTTAGGTGTAG
CTAACGCCGCAGAAATAGAA

Product: ATP-dependent Clp protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 810; Mature: 810

Protein sequence:

>810_residues
MFEKFTERARQVILRAREEALELGHSYLGSEHILLALIKDEDIPVLVLSKLGVSPEKIRKAIMGQITKGSHSGEVLFAPD
AKRVIEFAVEEARILHHQFVGPEHLLIGVVREKTGLGGRILRSFGLDEYSVRREVLQLLGELPPQESQRYVSTPNLDRFS
RDLTQMAREGKLDPVIGREKEIERVIQILVRRRKNNPVLLGDPGVGKTAIVEGLAQRIANKEVPEPLLNKRVVALDLAAL
VAGTKYRGQFEERLKNILKELEKANNVILFIDELHTLVGAGSAEGSIDASNMLKPALARGEIQVIGATTVDEYRKYIEKD
GALERRFQPVYVEQPSPEDTIQILYGLKPKFEEFHKVEYTPEAIEKAVELSVKYITDRNLPDKAIDVMDEAGALVKLKAT
QLPPELKEIEEKIKELEKEKEKAVKEQDYEKAAKIRDEELRLRAKFETMKAKWKEEMEKNRPKVTDEDVAEVVARWTGVP
VKRVHESDAEKLLHIEEELKKRVVGQDEAIKAVAKAIRRSRVGLKGKHRPIGVFMFLGPTGVGKTETAKALAEYLFGTED
ALIRFDMSEYMEKHTVSRLIGAPPGYVGYEEGGQLTEAVRRRPYSVLLFDEIEKAHPDVFNIFLQIFDDGRLTDGLGRTV
DFSNTIIIMTSNLGARLITGGTMGFEKKQGLLNFEEMRKNVLDQVKRTFSPEFLNRLDEIIVFRPLEKKDIEQILELQLK
EINEKLKDWNVRVKLHKSFVNWIIEKEYKPEFGARSLKRALQRHVEDLLAEELIKGTLKGVEEVEIRVRNDKPYLKPVKK
KEKVEALLEK

Sequences:

>Translated_810_residues
MFEKFTERARQVILRAREEALELGHSYLGSEHILLALIKDEDIPVLVLSKLGVSPEKIRKAIMGQITKGSHSGEVLFAPD
AKRVIEFAVEEARILHHQFVGPEHLLIGVVREKTGLGGRILRSFGLDEYSVRREVLQLLGELPPQESQRYVSTPNLDRFS
RDLTQMAREGKLDPVIGREKEIERVIQILVRRRKNNPVLLGDPGVGKTAIVEGLAQRIANKEVPEPLLNKRVVALDLAAL
VAGTKYRGQFEERLKNILKELEKANNVILFIDELHTLVGAGSAEGSIDASNMLKPALARGEIQVIGATTVDEYRKYIEKD
GALERRFQPVYVEQPSPEDTIQILYGLKPKFEEFHKVEYTPEAIEKAVELSVKYITDRNLPDKAIDVMDEAGALVKLKAT
QLPPELKEIEEKIKELEKEKEKAVKEQDYEKAAKIRDEELRLRAKFETMKAKWKEEMEKNRPKVTDEDVAEVVARWTGVP
VKRVHESDAEKLLHIEEELKKRVVGQDEAIKAVAKAIRRSRVGLKGKHRPIGVFMFLGPTGVGKTETAKALAEYLFGTED
ALIRFDMSEYMEKHTVSRLIGAPPGYVGYEEGGQLTEAVRRRPYSVLLFDEIEKAHPDVFNIFLQIFDDGRLTDGLGRTV
DFSNTIIIMTSNLGARLITGGTMGFEKKQGLLNFEEMRKNVLDQVKRTFSPEFLNRLDEIIVFRPLEKKDIEQILELQLK
EINEKLKDWNVRVKLHKSFVNWIIEKEYKPEFGARSLKRALQRHVEDLLAEELIKGTLKGVEEVEIRVRNDKPYLKPVKK
KEKVEALLEK
>Mature_810_residues
MFEKFTERARQVILRAREEALELGHSYLGSEHILLALIKDEDIPVLVLSKLGVSPEKIRKAIMGQITKGSHSGEVLFAPD
AKRVIEFAVEEARILHHQFVGPEHLLIGVVREKTGLGGRILRSFGLDEYSVRREVLQLLGELPPQESQRYVSTPNLDRFS
RDLTQMAREGKLDPVIGREKEIERVIQILVRRRKNNPVLLGDPGVGKTAIVEGLAQRIANKEVPEPLLNKRVVALDLAAL
VAGTKYRGQFEERLKNILKELEKANNVILFIDELHTLVGAGSAEGSIDASNMLKPALARGEIQVIGATTVDEYRKYIEKD
GALERRFQPVYVEQPSPEDTIQILYGLKPKFEEFHKVEYTPEAIEKAVELSVKYITDRNLPDKAIDVMDEAGALVKLKAT
QLPPELKEIEEKIKELEKEKEKAVKEQDYEKAAKIRDEELRLRAKFETMKAKWKEEMEKNRPKVTDEDVAEVVARWTGVP
VKRVHESDAEKLLHIEEELKKRVVGQDEAIKAVAKAIRRSRVGLKGKHRPIGVFMFLGPTGVGKTETAKALAEYLFGTED
ALIRFDMSEYMEKHTVSRLIGAPPGYVGYEEGGQLTEAVRRRPYSVLLFDEIEKAHPDVFNIFLQIFDDGRLTDGLGRTV
DFSNTIIIMTSNLGARLITGGTMGFEKKQGLLNFEEMRKNVLDQVKRTFSPEFLNRLDEIIVFRPLEKKDIEQILELQLK
EINEKLKDWNVRVKLHKSFVNWIIEKEYKPEFGARSLKRALQRHVEDLLAEELIKGTLKGVEEVEIRVRNDKPYLKPVKK
KEKVEALLEK

Specific function: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 UVR domain [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=332, Percent_Identity=36.7469879518072, Blast_Score=206, Evalue=1e-52,
Organism=Escherichia coli, GI1788943, Length=846, Percent_Identity=46.4539007092199, Blast_Score=715, Evalue=0.0,
Organism=Escherichia coli, GI1787109, Length=447, Percent_Identity=40.4921700223714, Blast_Score=306, Evalue=3e-84,
Organism=Saccharomyces cerevisiae, GI6320464, Length=740, Percent_Identity=45.945945945946, Blast_Score=613, Evalue=1e-176,
Organism=Saccharomyces cerevisiae, GI6323002, Length=872, Percent_Identity=37.5, Blast_Score=538, Evalue=1e-153,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150
- InterPro:   IPR001943 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small; PF02151 UVR [H]

EC number: NA

Molecular weight: Translated: 92357; Mature: 92357

Theoretical pI: Translated: 8.00; Mature: 8.00

Prosite motif: PS50151 UVR ; PS00870 CLPAB_1 ; PS00871 CLPAB_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFEKFTERARQVILRAREEALELGHSYLGSEHILLALIKDEDIPVLVLSKLGVSPEKIRK
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCEEEHHHCCCCHHHHHH
AIMGQITKGSHSGEVLFAPDAKRVIEFAVEEARILHHQFVGPEHLLIGVVREKTGLGGRI
HHHHHCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHH
LRSFGLDEYSVRREVLQLLGELPPQESQRYVSTPNLDRFSRDLTQMAREGKLDPVIGREK
HHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHH
EIERVIQILVRRRKNNPVLLGDPGVGKTAIVEGLAQRIANKEVPEPLLNKRVVALDLAAL
HHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHCCCCCCCHHHCCCHHHHHHHHH
VAGTKYRGQFEERLKNILKELEKANNVILFIDELHTLVGAGSAEGSIDASNMLKPALARG
HHCCCCCCHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHCCCCCCCCCCHHHHHHHHHCCC
EIQVIGATTVDEYRKYIEKDGALERRFQPVYVEQPSPEDTIQILYGLKPKFEEFHKVEYT
CEEEEECCCHHHHHHHHHHCCCHHHCCCCEEECCCCCHHHHHHHHCCCCCHHHHHHCCCC
PEAIEKAVELSVKYITDRNLPDKAIDVMDEAGALVKLKATQLPPELKEIEEKIKELEKEK
HHHHHHHHHHHHHEEECCCCCHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHH
EKAVKEQDYEKAAKIRDEELRLRAKFETMKAKWKEEMEKNRPKVTDEDVAEVVARWTGVP
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCC
VKRVHESDAEKLLHIEEELKKRVVGQDEAIKAVAKAIRRSRVGLKGKHRPIGVFMFLGPT
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCC
GVGKTETAKALAEYLFGTEDALIRFDMSEYMEKHTVSRLIGAPPGYVGYEEGGQLTEAVR
CCCCHHHHHHHHHHHHCCCHHHEEECHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHH
RRPYSVLLFDEIEKAHPDVFNIFLQIFDDGRLTDGLGRTVDFSNTIIIMTSNLGARLITG
HCCCEEEEEHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCEECCCEEEEEECCCCCEEEEC
GTMGFEKKQGLLNFEEMRKNVLDQVKRTFSPEFLNRLDEIIVFRPLEKKDIEQILELQLK
CCCCCHHHCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHEECCCCHHHHHHHHHHHHH
EINEKLKDWNVRVKLHKSFVNWIIEKEYKPEFGARSLKRALQRHVEDLLAEELIKGTLKG
HHHHHHHCCCEEEEEHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
VEEVEIRVRNDKPYLKPVKKKEKVEALLEK
HHEEEEEEECCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MFEKFTERARQVILRAREEALELGHSYLGSEHILLALIKDEDIPVLVLSKLGVSPEKIRK
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCEEEHHHCCCCHHHHHH
AIMGQITKGSHSGEVLFAPDAKRVIEFAVEEARILHHQFVGPEHLLIGVVREKTGLGGRI
HHHHHCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHH
LRSFGLDEYSVRREVLQLLGELPPQESQRYVSTPNLDRFSRDLTQMAREGKLDPVIGREK
HHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHH
EIERVIQILVRRRKNNPVLLGDPGVGKTAIVEGLAQRIANKEVPEPLLNKRVVALDLAAL
HHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHCCCCCCCHHHCCCHHHHHHHHH
VAGTKYRGQFEERLKNILKELEKANNVILFIDELHTLVGAGSAEGSIDASNMLKPALARG
HHCCCCCCHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHCCCCCCCCCCHHHHHHHHHCCC
EIQVIGATTVDEYRKYIEKDGALERRFQPVYVEQPSPEDTIQILYGLKPKFEEFHKVEYT
CEEEEECCCHHHHHHHHHHCCCHHHCCCCEEECCCCCHHHHHHHHCCCCCHHHHHHCCCC
PEAIEKAVELSVKYITDRNLPDKAIDVMDEAGALVKLKATQLPPELKEIEEKIKELEKEK
HHHHHHHHHHHHHEEECCCCCHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHH
EKAVKEQDYEKAAKIRDEELRLRAKFETMKAKWKEEMEKNRPKVTDEDVAEVVARWTGVP
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCC
VKRVHESDAEKLLHIEEELKKRVVGQDEAIKAVAKAIRRSRVGLKGKHRPIGVFMFLGPT
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCC
GVGKTETAKALAEYLFGTEDALIRFDMSEYMEKHTVSRLIGAPPGYVGYEEGGQLTEAVR
CCCCHHHHHHHHHHHHCCCHHHEEECHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHH
RRPYSVLLFDEIEKAHPDVFNIFLQIFDDGRLTDGLGRTVDFSNTIIIMTSNLGARLITG
HCCCEEEEEHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCEECCCEEEEEECCCCCEEEEC
GTMGFEKKQGLLNFEEMRKNVLDQVKRTFSPEFLNRLDEIIVFRPLEKKDIEQILELQLK
CCCCCHHHCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHEECCCCHHHHHHHHHHHHH
EINEKLKDWNVRVKLHKSFVNWIIEKEYKPEFGARSLKRALQRHVEDLLAEELIKGTLKG
HHHHHHHCCCEEEEEHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
VEEVEIRVRNDKPYLKPVKKKEKVEALLEK
HHEEEEEEECCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12235376 [H]