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The map label for this gene is flhA

Identifier: 15606449

GI number: 15606449

Start: 852069

End: 854105

Strand: Direct

Name: flhA

Synonym: aq_1212

Alternate gene names: 15606449

Gene position: 852069-854105 (Clockwise)

Preceding gene: 15606448

Following gene: 15606450

Centisome position: 54.92

GC content: 46.64

Gene sequence:

>2037_bases
ATGAGGGGAAAAGAGTTCTGGATAATACTCGCGGTAGTATTAATCCTCTCCGCGATAATAATCCCTATACCCGCCCTTCT
TCTGGATTTACTCCTCACCCTTTCAATAACCTTTTCCTTAACGGTTCTCCTTTTGACTTTTTTCATTAAAAACCCTCTTG
AGTTCTCTTCATTTCCCTCAGTTTTGCTCCTCGGAACACTCTTGAGGCTTTCTCTCAACATAGCGGCGGCGAGGAGGATA
CTCCTTCACGGACACGAAGGAACGCATGCAGCTGGTAAAGTAATAGAAGCCTTCGGGAAACTCGTGGCTGGAGGGGACGT
GGTAGTAGGTTTAATAGTCTTCCTGATATTCATAGTAATTAACTTCATAGTCATTACGAAGGGTGCGGAAAGGATTTCGG
AAGTGGCGGCTAGGTTTACTCTGGACGCCCTTCCCGGAAAGCAGATGTCCATAGACGCGGATCTGAACGCAGGTCTCATA
ACGGAAGAGGAGGCAAAAAGAAGAAGGCAGGAACTCGAAAAGGAAGCCAACTTCTACGCAGCGATGGACGGTGCGAGCAA
GTTCATAAGAGGAGACGCAATAGCGGCCCTGATAATCCTCTTCCTGAGTTTAGTGGGAGGACTGTTGATAGGGATAGGTA
TAAGGGGAATGGATCTGGCGAGTGCGGTAAAGACTTACACCATACTTTCCATAGGTGAAGGTCTGGCTTCTCAGGTTCCG
GCCCTGCTCCTTTCAACAGCGGCAGGTGTTCTAACCACAAAGATGTCCTCAAGGGAAAACCTCGGAGAGGCTATCAGTGA
GGAACTAACGAAGCAGCCAAGGGCACTTCTCTTTTCCGCAGGCGTTCTCGGTTTTATAGGTCTCATTCCCGGGCTTCCTA
CCCTTCCTTTCCTCGCTATGTCAGCAATCCTTGCCGGAGCTTACTACCTCGTTCAACAATCCCTGAAGGAAAGGGAGTTA
AAGGAACTGGAAAAATTGGCACAGGAGAAGACTAAGGAAAAGGAAGAGGAAGGGGAAGAGTTGATTCCTCAGCCCGAGCC
CATAACCCTTGAGATAGGCTACGCCCTCATCCCGCTCGTTGACGAGTCTCAGGGCGGACAGATACCGAAGAAGATAAAGA
ACTTGAGGAAGCAAATAGCGAAAGAGTACGGAGTGATCGTTCCCCTCATTCACATAAGGGATAACCTTAGGCTAAAACCA
AACGAGTACAGGATACTGATAAAAGGTATTGAGATAGACAGGTACGAACTTATGCCCGGGCACTACCTCGCGGTGAACCT
TGGAAACGCAAAAGGTCCAATAGAAGGAATAGAGACTTACGACCCCGCCTTTAAGATAAAGGCTTACTGGATTACGGAAG
ACAAAAAGGAAGAAGCTCAGAAGCTCGGTTACATGGTAGTGGACGCGGAAACGGTTTTAATCACGCACCTCTCGGAAGTG
ATAAAGAGGAACCTTCACGAACTCCTTACCAGAAACGAAGTAATGGAACTTATAGAAATGCTTTCTAAGAAGTATCCGAA
AGTCGTAAAGGAAATAGTCCCGGAACAGGTTCCCATATCCATAATACACAGGGTTCTCCAGAATTTACTGAGGGAGGGCA
TACCCGTAAACGACCTGCTCACCATACTCGAAACACTTGCGGACTACATAGAACAGACCAAAGACCCGGACCTCTTAACG
GAGTATGTAAGGCAGGCACTCTCTAAACGCATAACAAGGATGTACCTTACCAACGGAACTCTTTACGCAATAGCCCTGTC
TCCGAAAGTAGAGGCTAAACTCGTGAAATTTTTAAAAGAGAACAGGGAAGACGAGTTCATAGACTACGTTCTGAATACAC
TCCTTCCGAAGATAAAGAACGAGATTGTCAAGTTTGCCCAGTACGGAGCTGTTCCGGTTTTGTTAACTTCCGGGGAAGTG
AGGCGGTTTGTGAGAAAAACGATAGAGCCCTACCTTTCCGAACTTGCGGTTCTATCTTACAACGAACTAGAAAAGCAAGT
TAATATAAAAATTATAGGTATAGTGGATGAAGATTGA

Upstream 100 bases:

>100_bases
TTAAGTTCGTGGATCTCAGCACGAGGTACGAGAACATTATCGGAAGGTACGTTATGAAGAGACAGATGGAAATCCTCAAG
GAGCTTAAAGAGAGTATGAT

Downstream 100 bases:

>100_bases
GAAAATAGAGGTAAACTCCTTACAGGAAGCTATAGAGATAGTGGAGAGGAGGTTTGGAGAAAACGCGGTAATACTTTCCT
CAAGAGTTATTAGGAAAAAC

Product: flagellar export protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 678; Mature: 678

Protein sequence:

>678_residues
MRGKEFWIILAVVLILSAIIIPIPALLLDLLLTLSITFSLTVLLLTFFIKNPLEFSSFPSVLLLGTLLRLSLNIAAARRI
LLHGHEGTHAAGKVIEAFGKLVAGGDVVVGLIVFLIFIVINFIVITKGAERISEVAARFTLDALPGKQMSIDADLNAGLI
TEEEAKRRRQELEKEANFYAAMDGASKFIRGDAIAALIILFLSLVGGLLIGIGIRGMDLASAVKTYTILSIGEGLASQVP
ALLLSTAAGVLTTKMSSRENLGEAISEELTKQPRALLFSAGVLGFIGLIPGLPTLPFLAMSAILAGAYYLVQQSLKEREL
KELEKLAQEKTKEKEEEGEELIPQPEPITLEIGYALIPLVDESQGGQIPKKIKNLRKQIAKEYGVIVPLIHIRDNLRLKP
NEYRILIKGIEIDRYELMPGHYLAVNLGNAKGPIEGIETYDPAFKIKAYWITEDKKEEAQKLGYMVVDAETVLITHLSEV
IKRNLHELLTRNEVMELIEMLSKKYPKVVKEIVPEQVPISIIHRVLQNLLREGIPVNDLLTILETLADYIEQTKDPDLLT
EYVRQALSKRITRMYLTNGTLYAIALSPKVEAKLVKFLKENREDEFIDYVLNTLLPKIKNEIVKFAQYGAVPVLLTSGEV
RRFVRKTIEPYLSELAVLSYNELEKQVNIKIIGIVDED

Sequences:

>Translated_678_residues
MRGKEFWIILAVVLILSAIIIPIPALLLDLLLTLSITFSLTVLLLTFFIKNPLEFSSFPSVLLLGTLLRLSLNIAAARRI
LLHGHEGTHAAGKVIEAFGKLVAGGDVVVGLIVFLIFIVINFIVITKGAERISEVAARFTLDALPGKQMSIDADLNAGLI
TEEEAKRRRQELEKEANFYAAMDGASKFIRGDAIAALIILFLSLVGGLLIGIGIRGMDLASAVKTYTILSIGEGLASQVP
ALLLSTAAGVLTTKMSSRENLGEAISEELTKQPRALLFSAGVLGFIGLIPGLPTLPFLAMSAILAGAYYLVQQSLKEREL
KELEKLAQEKTKEKEEEGEELIPQPEPITLEIGYALIPLVDESQGGQIPKKIKNLRKQIAKEYGVIVPLIHIRDNLRLKP
NEYRILIKGIEIDRYELMPGHYLAVNLGNAKGPIEGIETYDPAFKIKAYWITEDKKEEAQKLGYMVVDAETVLITHLSEV
IKRNLHELLTRNEVMELIEMLSKKYPKVVKEIVPEQVPISIIHRVLQNLLREGIPVNDLLTILETLADYIEQTKDPDLLT
EYVRQALSKRITRMYLTNGTLYAIALSPKVEAKLVKFLKENREDEFIDYVLNTLLPKIKNEIVKFAQYGAVPVLLTSGEV
RRFVRKTIEPYLSELAVLSYNELEKQVNIKIIGIVDED
>Mature_678_residues
MRGKEFWIILAVVLILSAIIIPIPALLLDLLLTLSITFSLTVLLLTFFIKNPLEFSSFPSVLLLGTLLRLSLNIAAARRI
LLHGHEGTHAAGKVIEAFGKLVAGGDVVVGLIVFLIFIVINFIVITKGAERISEVAARFTLDALPGKQMSIDADLNAGLI
TEEEAKRRRQELEKEANFYAAMDGASKFIRGDAIAALIILFLSLVGGLLIGIGIRGMDLASAVKTYTILSIGEGLASQVP
ALLLSTAAGVLTTKMSSRENLGEAISEELTKQPRALLFSAGVLGFIGLIPGLPTLPFLAMSAILAGAYYLVQQSLKEREL
KELEKLAQEKTKEKEEEGEELIPQPEPITLEIGYALIPLVDESQGGQIPKKIKNLRKQIAKEYGVIVPLIHIRDNLRLKP
NEYRILIKGIEIDRYELMPGHYLAVNLGNAKGPIEGIETYDPAFKIKAYWITEDKKEEAQKLGYMVVDAETVLITHLSEV
IKRNLHELLTRNEVMELIEMLSKKYPKVVKEIVPEQVPISIIHRVLQNLLREGIPVNDLLTILETLADYIEQTKDPDLLT
EYVRQALSKRITRMYLTNGTLYAIALSPKVEAKLVKFLKENREDEFIDYVLNTLLPKIKNEIVKFAQYGAVPVLLTSGEV
RRFVRKTIEPYLSELAVLSYNELEKQVNIKIIGIVDED

Specific function: Required for formation of the rod structure of the flagellar apparatus. Together with fliI and fliH, may constitute the export apparatus of flagellin

COG id: COG1298

COG function: function code NU; Flagellar biosynthesis pathway, component FlhA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family

Homologues:

Organism=Escherichia coli, GI1788187, Length=675, Percent_Identity=43.5555555555556, Blast_Score=553, Evalue=1e-158,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): FLHA_AQUAE (O67265)

Other databases:

- EMBL:   AE000657
- PIR:   F70404
- RefSeq:   NP_213829.1
- GeneID:   1192611
- GenomeReviews:   AE000657_GR
- KEGG:   aae:aq_1212
- NMPDR:   fig|224324.1.peg.844
- HOGENOM:   HBG595253
- OMA:   LVLINFM
- PhylomeDB:   O67265
- ProtClustDB:   CLSK871706
- BioCyc:   AAEO224324:AQ_1212-MONOMER
- GO:   GO:0019861
- InterPro:   IPR006301
- InterPro:   IPR001712
- PRINTS:   PR00949
- TIGRFAMs:   TIGR01398

Pfam domain/function: PF00771 FHIPEP

EC number: NA

Molecular weight: Translated: 75393; Mature: 75393

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: PS00994 FHIPEP

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xd83c3e0)-; HASH(0xb3e5cb4)-; HASH(0xb77b14c)-; HASH(0xd1d86cc)-; HASH(0xd76f880)-; HASH(0xc13bb18)-; HASH(0xbe629bc)-; HASH(0xccb6648)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRGKEFWIILAVVLILSAIIIPIPALLLDLLLTLSITFSLTVLLLTFFIKNPLEFSSFPS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCH
VLLLGTLLRLSLNIAAARRILLHGHEGTHAAGKVIEAFGKLVAGGDVVVGLIVFLIFIVI
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
NFIVITKGAERISEVAARFTLDALPGKQMSIDADLNAGLITEEEAKRRRQELEKEANFYA
HHHHHCCCHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHCCHHH
AMDGASKFIRGDAIAALIILFLSLVGGLLIGIGIRGMDLASAVKTYTILSIGEGLASQVP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHH
ALLLSTAAGVLTTKMSSRENLGEAISEELTKQPRALLFSAGVLGFIGLIPGLPTLPFLAM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCHHHHHHH
SAILAGAYYLVQQSLKERELKELEKLAQEKTKEKEEEGEELIPQPEPITLEIGYALIPLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCEEEEECCEEEEEE
DESQGGQIPKKIKNLRKQIAKEYGVIVPLIHIRDNLRLKPNEYRILIKGIEIDRYELMPG
ECCCCCCCHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCEEEEEEECEECCEEECCC
HYLAVNLGNAKGPIEGIETYDPAFKIKAYWITEDKKEEAQKLGYMVVDAETVLITHLSEV
CEEEEEECCCCCCCCCCCCCCCCEEEEEEEECCCHHHHHHHCCEEEEEHHHHHHHHHHHH
IKRNLHELLTRNEVMELIEMLSKKYPKVVKEIVPEQVPISIIHRVLQNLLREGIPVNDLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHH
TILETLADYIEQTKDPDLLTEYVRQALSKRITRMYLTNGTLYAIALSPKVEAKLVKFLKE
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHEECCEEEEEEECCCHHHHHHHHHHH
NREDEFIDYVLNTLLPKIKNEIVKFAQYGAVPVLLTSGEVRRFVRKTIEPYLSELAVLSY
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHH
NELEKQVNIKIIGIVDED
HHHHHHCCEEEEEEECCH
>Mature Secondary Structure
MRGKEFWIILAVVLILSAIIIPIPALLLDLLLTLSITFSLTVLLLTFFIKNPLEFSSFPS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCH
VLLLGTLLRLSLNIAAARRILLHGHEGTHAAGKVIEAFGKLVAGGDVVVGLIVFLIFIVI
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
NFIVITKGAERISEVAARFTLDALPGKQMSIDADLNAGLITEEEAKRRRQELEKEANFYA
HHHHHCCCHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHCCHHH
AMDGASKFIRGDAIAALIILFLSLVGGLLIGIGIRGMDLASAVKTYTILSIGEGLASQVP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHH
ALLLSTAAGVLTTKMSSRENLGEAISEELTKQPRALLFSAGVLGFIGLIPGLPTLPFLAM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCHHHHHHH
SAILAGAYYLVQQSLKERELKELEKLAQEKTKEKEEEGEELIPQPEPITLEIGYALIPLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCEEEEECCEEEEEE
DESQGGQIPKKIKNLRKQIAKEYGVIVPLIHIRDNLRLKPNEYRILIKGIEIDRYELMPG
ECCCCCCCHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCEEEEEEECEECCEEECCC
HYLAVNLGNAKGPIEGIETYDPAFKIKAYWITEDKKEEAQKLGYMVVDAETVLITHLSEV
CEEEEEECCCCCCCCCCCCCCCCEEEEEEEECCCHHHHHHHCCEEEEEHHHHHHHHHHHH
IKRNLHELLTRNEVMELIEMLSKKYPKVVKEIVPEQVPISIIHRVLQNLLREGIPVNDLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHH
TILETLADYIEQTKDPDLLTEYVRQALSKRITRMYLTNGTLYAIALSPKVEAKLVKFLKE
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHEECCEEEEEEECCCHHHHHHHHHHH
NREDEFIDYVLNTLLPKIKNEIVKFAQYGAVPVLLTSGEVRRFVRKTIEPYLSELAVLSY
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHH
NELEKQVNIKIIGIVDED
HHHHHHCCEEEEEEECCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9537320