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The map label for this gene is flhF

Identifier: 15606450

GI number: 15606450

Start: 854095

End: 855216

Strand: Direct

Name: flhF

Synonym: aq_1214

Alternate gene names: 15606450

Gene position: 854095-855216 (Clockwise)

Preceding gene: 15606449

Following gene: 15606451

Centisome position: 55.06

GC content: 41.44

Gene sequence:

>1122_bases
ATGAAGATTGAGAAAATAGAGGTAAACTCCTTACAGGAAGCTATAGAGATAGTGGAGAGGAGGTTTGGAGAAAACGCGGT
AATACTTTCCTCAAGAGTTATTAGGAAAAACAGGTTTGGCTTTTTACCCATATTCAGGAAGAAGATACTGGAAGTAACAG
TTGGTATTCGAGAAGAAGAGGACTTTAGAAAGGAATTTGAAAGGGAGAGGGAACTTATAAAAGAAATAGAAAACCTGAAA
AAGATTGTAAACGAACTCATAAACAACGGAGAGGTCAAAGGGGAAAAAATCGTAGAAAAGGGTTCCGACACTTACGCGCC
GAGAGTAAAAAGGTATTTGGAAAAGCTCGTTATAAAGAACATAAGTAAGAACATAGCGGAGAAGATAATTCAGGACGCAT
GCGGTTACGATATAGACAACAAGATTTACGACTTCAAGGATGAACCTTACACTTCGTTGAGAGAAAGCATAGAGAAAAAC
ATAAAACTGAATGAGGAGTTTATTCAAAACCCGCCGAAAGTTGTCGCTTTGGTTGGACCAACTGGTGTGGGGAAAACCAC
TACTCTTGCAAAGCTTGCCCACCTCTTCAAGAAGAACAAGAAGAAGGTAGGTATTATTTCCCTTGATTGTTTCAGAGTTG
GGGCTTTTGAGCAGTTAAAAGCTTTTGCGGAAGTACTGGAAGTTCCCTTCAAACTTGCGGACTCGCCGAGAGCCTTTAAC
ATTCAACTCCTCGAAATGGACGACAGGGATGTAATACTCGTAGATACCGCGGGAAGGAGTCATTACGATGTCATAAGACT
CAAGGAACTTGAAACGTATTTTAAAGTCTCCGACATAAGCGTATACCTCACACTTGCGGCGAACCTTTCCGAACTCGTCA
TGTACGAAGCCATAATGCAGTTTGGAATGTTCTCTATAAGCGGGCTTATATTCACAAAGCTCGACGAGACACCTTATCCA
GGGAGTATGGTAAACGTAGCCTACAGAACCCAGTATCCGGTTGTGTGCTTCACGATGGGGCAATCCATACCTGAAGACAT
TGTGGTTGCAAATTACGATTACTTAGTCCGATTAATCTTAGAGGATGAAGATGAAGTTAGACCAGCAACTCAACTTGCTT
AA

Upstream 100 bases:

>100_bases
TTTGTGAGAAAAACGATAGAGCCCTACCTTTCCGAACTTGCGGTTCTATCTTACAACGAACTAGAAAAGCAAGTTAATAT
AAAAATTATAGGTATAGTGG

Downstream 100 bases:

>100_bases
ACATATGCTCGGAAAGAGCAAGGGCACGCGTTACATATCCGTGTCCAGCGGGAAAGGAGGTGTAGGGAAAACACTCGTCT
CCATAAACATAGGCGAGATA

Product: flagellar biosynthesis FlhF

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 373; Mature: 373

Protein sequence:

>373_residues
MKIEKIEVNSLQEAIEIVERRFGENAVILSSRVIRKNRFGFLPIFRKKILEVTVGIREEEDFRKEFERERELIKEIENLK
KIVNELINNGEVKGEKIVEKGSDTYAPRVKRYLEKLVIKNISKNIAEKIIQDACGYDIDNKIYDFKDEPYTSLRESIEKN
IKLNEEFIQNPPKVVALVGPTGVGKTTTLAKLAHLFKKNKKKVGIISLDCFRVGAFEQLKAFAEVLEVPFKLADSPRAFN
IQLLEMDDRDVILVDTAGRSHYDVIRLKELETYFKVSDISVYLTLAANLSELVMYEAIMQFGMFSISGLIFTKLDETPYP
GSMVNVAYRTQYPVVCFTMGQSIPEDIVVANYDYLVRLILEDEDEVRPATQLA

Sequences:

>Translated_373_residues
MKIEKIEVNSLQEAIEIVERRFGENAVILSSRVIRKNRFGFLPIFRKKILEVTVGIREEEDFRKEFERERELIKEIENLK
KIVNELINNGEVKGEKIVEKGSDTYAPRVKRYLEKLVIKNISKNIAEKIIQDACGYDIDNKIYDFKDEPYTSLRESIEKN
IKLNEEFIQNPPKVVALVGPTGVGKTTTLAKLAHLFKKNKKKVGIISLDCFRVGAFEQLKAFAEVLEVPFKLADSPRAFN
IQLLEMDDRDVILVDTAGRSHYDVIRLKELETYFKVSDISVYLTLAANLSELVMYEAIMQFGMFSISGLIFTKLDETPYP
GSMVNVAYRTQYPVVCFTMGQSIPEDIVVANYDYLVRLILEDEDEVRPATQLA
>Mature_373_residues
MKIEKIEVNSLQEAIEIVERRFGENAVILSSRVIRKNRFGFLPIFRKKILEVTVGIREEEDFRKEFERERELIKEIENLK
KIVNELINNGEVKGEKIVEKGSDTYAPRVKRYLEKLVIKNISKNIAEKIIQDACGYDIDNKIYDFKDEPYTSLRESIEKN
IKLNEEFIQNPPKVVALVGPTGVGKTTTLAKLAHLFKKNKKKVGIISLDCFRVGAFEQLKAFAEVLEVPFKLADSPRAFN
IQLLEMDDRDVILVDTAGRSHYDVIRLKELETYFKVSDISVYLTLAANLSELVMYEAIMQFGMFSISGLIFTKLDETPYP
GSMVNVAYRTQYPVVCFTMGQSIPEDIVVANYDYLVRLILEDEDEVRPATQLA

Specific function: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum

COG id: COG1419

COG function: function code N; Flagellar GTP-binding protein

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family

Homologues:

Organism=Homo sapiens, GI4507215, Length=179, Percent_Identity=25.6983240223464, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI226371618, Length=177, Percent_Identity=25.9887005649718, Blast_Score=67, Evalue=4e-11,
Organism=Escherichia coli, GI1789874, Length=206, Percent_Identity=30.0970873786408, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1788963, Length=192, Percent_Identity=29.6875, Blast_Score=78, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI193206261, Length=277, Percent_Identity=27.7978339350181, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17539958, Length=177, Percent_Identity=28.2485875706215, Blast_Score=72, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6325345, Length=184, Percent_Identity=27.1739130434783, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24641198, Length=303, Percent_Identity=25.0825082508251, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI17647949, Length=185, Percent_Identity=27.5675675675676, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FLHF_AQUAE (O67266)

Other databases:

- EMBL:   AE000657
- PIR:   G70404
- RefSeq:   NP_213830.1
- ProteinModelPortal:   O67266
- SMR:   O67266
- GeneID:   1192612
- GenomeReviews:   AE000657_GR
- KEGG:   aae:aq_1214
- NMPDR:   fig|224324.1.peg.845
- HOGENOM:   HBG507497
- OMA:   GKTTNLF
- PhylomeDB:   O67266
- ProtClustDB:   CLSK2299620
- BioCyc:   AAEO224324:AQ_1214-MONOMER
- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR020006
- SMART:   SM00382
- SMART:   SM00962
- TIGRFAMs:   TIGR03499

Pfam domain/function: PF00448 SRP54

EC number: NA

Molecular weight: Translated: 42827; Mature: 42827

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: PS00300 SRP54

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIEKIEVNSLQEAIEIVERRFGENAVILSSRVIRKNRFGFLPIFRKKILEVTVGIREEE
CCCEEEHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCH
DFRKEFERERELIKEIENLKKIVNELINNGEVKGEKIVEKGSDTYAPRVKRYLEKLVIKN
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHH
ISKNIAEKIIQDACGYDIDNKIYDFKDEPYTSLRESIEKNIKLNEEFIQNPPKVVALVGP
HHHHHHHHHHHHHCCCCCCCCEECCCCCCHHHHHHHHHHCCCCCHHHHCCCCCEEEEECC
TGVGKTTTLAKLAHLFKKNKKKVGIISLDCFRVGAFEQLKAFAEVLEVPFKLADSPRAFN
CCCCCHHHHHHHHHHHHCCCCEEEEEEEEHHCCCCHHHHHHHHHHHHCCHHHCCCCCEEE
IQLLEMDDRDVILVDTAGRSHYDVIRLKELETYFKVSDISVYLTLAANLSELVMYEAIMQ
EEEEEECCCCEEEEECCCCCCHHHHHHHHHHHHHEEECEEEEEEEHHCHHHHHHHHHHHH
FGMFSISGLIFTKLDETPYPGSMVNVAYRTQYPVVCFTMGQSIPEDIVVANYDYLVRLIL
HHHHHHCCEEEEECCCCCCCCCEEEEEEECCCCEEEEECCCCCCCCCEEECHHHEEEEEE
EDEDEVRPATQLA
CCCHHCCCHHCCC
>Mature Secondary Structure
MKIEKIEVNSLQEAIEIVERRFGENAVILSSRVIRKNRFGFLPIFRKKILEVTVGIREEE
CCCEEEHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCH
DFRKEFERERELIKEIENLKKIVNELINNGEVKGEKIVEKGSDTYAPRVKRYLEKLVIKN
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHH
ISKNIAEKIIQDACGYDIDNKIYDFKDEPYTSLRESIEKNIKLNEEFIQNPPKVVALVGP
HHHHHHHHHHHHHCCCCCCCCEECCCCCCHHHHHHHHHHCCCCCHHHHCCCCCEEEEECC
TGVGKTTTLAKLAHLFKKNKKKVGIISLDCFRVGAFEQLKAFAEVLEVPFKLADSPRAFN
CCCCCHHHHHHHHHHHHCCCCEEEEEEEEHHCCCCHHHHHHHHHHHHCCHHHCCCCCEEE
IQLLEMDDRDVILVDTAGRSHYDVIRLKELETYFKVSDISVYLTLAANLSELVMYEAIMQ
EEEEEECCCCEEEEECCCCCCHHHHHHHHHHHHHEEECEEEEEEEHHCHHHHHHHHHHHH
FGMFSISGLIFTKLDETPYPGSMVNVAYRTQYPVVCFTMGQSIPEDIVVANYDYLVRLIL
HHHHHHCCEEEEECCCCCCCCCEEEEEEECCCCEEEEECCCCCCCCCEEECHHHEEEEEE
EDEDEVRPATQLA
CCCHHCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9537320