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The map label for this gene is accA

Identifier: 15606444

GI number: 15606444

Start: 847969

End: 848940

Strand: Direct

Name: accA

Synonym: aq_1206

Alternate gene names: 15606444

Gene position: 847969-848940 (Clockwise)

Preceding gene: 15606442

Following gene: 15606448

Centisome position: 54.66

GC content: 48.46

Gene sequence:

>972_bases
ATGATATTATTCAAAGTTATGCACCTAGAGTTCGAAAAAGAGCTCTTAGAAATAAAGGAAAAGATAGACAGACTCCTGGG
TCTTTACAGACTCGGAAAGGAGGAGGTTCTATCCGAACTGGACGAACTCAGGAAGAAGTTCAAGGAAAAGGCCAGGAAAA
TTTACAGGGACCTCTCCCCTTGGGAAAGGGTTCAGGTGGCAAGACATCCCAAGCGTCCTCACACCTCAGACTACATAAAG
TACTTAATAAAGGATTTTGAAGAGGTTCACGGAGACACCTGCTACGGCGACGACAAGGCGGTAATTGCGGGTTTTGGATA
CTTCAGGGGAAAGCCCGTGGCAGTCGTGGGGCACGAGAAGGGAAAGGACACGAAAGAAAAACTGGAGAGAAACTTCGGTA
TGCCCCACCCTGAGGGCTACAGAAAAGCCATAAAGGTTTTCAAACTGGCAGAAAGGTACAATATTCCCGTCATAACTTTT
ATAGACACACCGGGAGCTTTTCCAGGAATAGGAGCGGAAGAGAGAGGGCAGTCCAGAGCTATAGCGGAAAGTATGCTTAC
CATGGCGTTTTTAAAAGTTCCCTCCGTTGCGGTTGTAATAGGCGAGGGCGGAAGCGGCGGAGCGCTCGCCTTCGGTGTGG
CAAACAGGGTTTGTATCCTTGAGAACGCCTACTACTCCGTCATTTCTCCCGAGGGTTGTGCCGCTATACTTTGGAAGGAT
CAGAGCAAGGTAAAGGAGGCGGCAAAGGCCCTAAGGCTCACCGCAAAAGACCTTAAGGAACTTGGGGTGGTGGACTGCGT
AATTCCTGAACCCTACGGTGCAGCTCACTGGAGTCCAAGGGGAACGGCTATGATGGTTGGAATGACATTAAAGAAGTGTT
TAGACGAACTCTCAAAATTGACGGAAGAGGGTGTGGTGAGGAGCAGACTGGAGAAGTTTAAAAATATGGGAGCTTTTAAG
ATTGCATCTTAG

Upstream 100 bases:

>100_bases
AACCTCTTCCTCTTCTCTACCCACTCAGCTCTTAGCATACGCTAACCTCCTAAAAAGAAGTTTTATTCTTAAACTTAATA
CCGTAGGTTTTTTATTCAAC

Downstream 100 bases:

>100_bases
CCCTGCAGTCTGGGCAAATTCCGTATACGTTCACCGAGTAACTTTCCGTTTTGTAGCCGTAGAACTCTTCGGGTATGTTT
AGTTTTTGATCCAGTTTTAT

Product: acetyl-CoA carboxylase alpha subunit

Products: NA

Alternate protein names: ACCase subunit alpha; Acetyl-CoA carboxylase carboxyltransferase subunit alpha

Number of amino acids: Translated: 323; Mature: 323

Protein sequence:

>323_residues
MILFKVMHLEFEKELLEIKEKIDRLLGLYRLGKEEVLSELDELRKKFKEKARKIYRDLSPWERVQVARHPKRPHTSDYIK
YLIKDFEEVHGDTCYGDDKAVIAGFGYFRGKPVAVVGHEKGKDTKEKLERNFGMPHPEGYRKAIKVFKLAERYNIPVITF
IDTPGAFPGIGAEERGQSRAIAESMLTMAFLKVPSVAVVIGEGGSGGALAFGVANRVCILENAYYSVISPEGCAAILWKD
QSKVKEAAKALRLTAKDLKELGVVDCVIPEPYGAAHWSPRGTAMMVGMTLKKCLDELSKLTEEGVVRSRLEKFKNMGAFK
IAS

Sequences:

>Translated_323_residues
MILFKVMHLEFEKELLEIKEKIDRLLGLYRLGKEEVLSELDELRKKFKEKARKIYRDLSPWERVQVARHPKRPHTSDYIK
YLIKDFEEVHGDTCYGDDKAVIAGFGYFRGKPVAVVGHEKGKDTKEKLERNFGMPHPEGYRKAIKVFKLAERYNIPVITF
IDTPGAFPGIGAEERGQSRAIAESMLTMAFLKVPSVAVVIGEGGSGGALAFGVANRVCILENAYYSVISPEGCAAILWKD
QSKVKEAAKALRLTAKDLKELGVVDCVIPEPYGAAHWSPRGTAMMVGMTLKKCLDELSKLTEEGVVRSRLEKFKNMGAFK
IAS
>Mature_323_residues
MILFKVMHLEFEKELLEIKEKIDRLLGLYRLGKEEVLSELDELRKKFKEKARKIYRDLSPWERVQVARHPKRPHTSDYIK
YLIKDFEEVHGDTCYGDDKAVIAGFGYFRGKPVAVVGHEKGKDTKEKLERNFGMPHPEGYRKAIKVFKLAERYNIPVITF
IDTPGAFPGIGAEERGQSRAIAESMLTMAFLKVPSVAVVIGEGGSGGALAFGVANRVCILENAYYSVISPEGCAAILWKD
QSKVKEAAKALRLTAKDLKELGVVDCVIPEPYGAAHWSPRGTAMMVGMTLKKCLDELSKLTEEGVVRSRLEKFKNMGAFK
IAS

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-Co

COG id: COG0825

COG function: function code I; Acetyl-CoA carboxylase alpha subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccA family

Homologues:

Organism=Escherichia coli, GI1786382, Length=312, Percent_Identity=48.3974358974359, Blast_Score=317, Evalue=5e-88,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACCA_AQUAE (O67260)

Other databases:

- EMBL:   AE000657
- PIR:   A70404
- RefSeq:   NP_213824.1
- ProteinModelPortal:   O67260
- SMR:   O67260
- GeneID:   1192606
- GenomeReviews:   AE000657_GR
- KEGG:   aae:aq_1206
- NMPDR:   fig|224324.1.peg.839
- HOGENOM:   HBG286557
- OMA:   QLTKDIY
- PhylomeDB:   O67260
- ProtClustDB:   CLSK2748426
- BioCyc:   AAEO224324:AQ_1206-MONOMER
- BRENDA:   6.4.1.2
- HAMAP:   MF_00823
- InterPro:   IPR001095
- InterPro:   IPR011763
- PANTHER:   PTHR22855:SF3
- PRINTS:   PR01069
- TIGRFAMs:   TIGR00513

Pfam domain/function: PF03255 ACCA

EC number: =6.4.1.2

Molecular weight: Translated: 36199; Mature: 36199

Theoretical pI: Translated: 9.46; Mature: 9.46

Prosite motif: PS50989 COA_CT_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILFKVMHLEFEKELLEIKEKIDRLLGLYRLGKEEVLSELDELRKKFKEKARKIYRDLSP
CEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCH
WERVQVARHPKRPHTSDYIKYLIKDFEEVHGDTCYGDDKAVIAGFGYFRGKPVAVVGHEK
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECHHHCCCCEEEEECCC
GKDTKEKLERNFGMPHPEGYRKAIKVFKLAERYNIPVITFIDTPGAFPGIGAEERGQSRA
CCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHCCHHHH
IAESMLTMAFLKVPSVAVVIGEGGSGGALAFGVANRVCILENAYYSVISPEGCAAILWKD
HHHHHHHHHHHHCCCEEEEEECCCCCCEEEHHHHCCEEEEECCHHEEECCCCCEEEEECC
QSKVKEAAKALRLTAKDLKELGVVDCVIPEPYGAAHWSPRGTAMMVGMTLKKCLDELSKL
HHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHH
TEEGVVRSRLEKFKNMGAFKIAS
HHHHHHHHHHHHHHCCCCEEECC
>Mature Secondary Structure
MILFKVMHLEFEKELLEIKEKIDRLLGLYRLGKEEVLSELDELRKKFKEKARKIYRDLSP
CEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCH
WERVQVARHPKRPHTSDYIKYLIKDFEEVHGDTCYGDDKAVIAGFGYFRGKPVAVVGHEK
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECHHHCCCCEEEEECCC
GKDTKEKLERNFGMPHPEGYRKAIKVFKLAERYNIPVITFIDTPGAFPGIGAEERGQSRA
CCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHCCHHHH
IAESMLTMAFLKVPSVAVVIGEGGSGGALAFGVANRVCILENAYYSVISPEGCAAILWKD
HHHHHHHHHHHHCCCEEEEEECCCCCCEEEHHHHCCEEEEECCHHEEECCCCCEEEEECC
QSKVKEAAKALRLTAKDLKELGVVDCVIPEPYGAAHWSPRGTAMMVGMTLKKCLDELSKL
HHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHH
TEEGVVRSRLEKFKNMGAFKIAS
HHHHHHHHHHHHHHCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320