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The map label for this gene is lysR2 [H]

Identifier: 15606329

GI number: 15606329

Start: 719732

End: 720652

Strand: Direct

Name: lysR2 [H]

Synonym: aq_1038

Alternate gene names: 15606329

Gene position: 719732-720652 (Clockwise)

Preceding gene: 15606325

Following gene: 15606330

Centisome position: 46.39

GC content: 30.4

Gene sequence:

>921_bases
ATGGTACGAAATTTATTTTTTCATTTTATGAAGGATATTGATTTGAAATTGATTGAAATATTCTGTTATGTTTATGAATA
TAAAAGTGTTACAAAAGCCTCAAGTGAACTTAATATGTCTCAATCTACTATTTCATTTCATATGAAAAATTTAGAAACTC
AATTAGGCCAAAAGTTATTTTATCGTAAGGGAAAAACGCTGATTCCAACTGCGTTTGCGGATAAGTTATACGAGTATGCC
ACAGAGCTAACAAATTTCAAGAGACGTATGCTTGAAGATATAACAAAGTTTTCTGGAAAAAACGGGGGTGTAATCAGAAT
AGGTGCCAGTAGTATTCCAGGAAACTACCTTCTTCCACAATTACTTGGGGAATTTATTGAAAATTTTAAAGGTTATGTAA
ACGTGGAGCTTAGAGTAAGTGATAGCCAGGATATATATGAAAAAGTAATAAATGGAGACGTAGATTTAGGAATTATAGGT
TATCTGCCGAGAACAAATAAAGTGGATGCTATTAAATTTTATACCGATAGAATACTAATTGTAGGCAATCCAGAACTTGA
AGATAAGGTATATACCTTAGAAGAGCTGATAAACTTACCTTTAGTTATAAGAGAAGTTGGTTCAGGAACGAGAAGTATTG
TTGAAGACAAATTAAGAGAAAAAGGTTTATCCTTAAAAGAAATGAATATAGTAGCTGTATGTAACAGTAATGAAGCCGTT
AAAAATACGCTTAAATACGTTAAGGGATTTTCCTTCCTTTCTAGCTATGTTGTAAAAGATGATAAGTTTTTGATTAAATT
AAAAGTAAAAAATTTTGACGATATAACCAGACAGTTTTACTTAATTCGAGACAAAAAACGTCCCTTACCATTTCTTACAC
AGGAGCTTATTAAGTTCTTAATAAAAGACATTTATGTTTAA

Upstream 100 bases:

>100_bases
TTGTCTTCTGTTTTTACCACCTTTTCGCTCCCGTACTCAGGACACCTCATAGCTTATATTCTCTTATCATCTCTTTTGTG
AACTACCATATGGAAAAGAG

Downstream 100 bases:

>100_bases
TTTTTCGAACATTTTCATTGAATAATTAAATAAATAAGTTATGTGATATTTGAATATAAGGAATTTATTAACATGCAATA
TGCATTGATACACAATAAAA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MVRNLFFHFMKDIDLKLIEIFCYVYEYKSVTKASSELNMSQSTISFHMKNLETQLGQKLFYRKGKTLIPTAFADKLYEYA
TELTNFKRRMLEDITKFSGKNGGVIRIGASSIPGNYLLPQLLGEFIENFKGYVNVELRVSDSQDIYEKVINGDVDLGIIG
YLPRTNKVDAIKFYTDRILIVGNPELEDKVYTLEELINLPLVIREVGSGTRSIVEDKLREKGLSLKEMNIVAVCNSNEAV
KNTLKYVKGFSFLSSYVVKDDKFLIKLKVKNFDDITRQFYLIRDKKRPLPFLTQELIKFLIKDIYV

Sequences:

>Translated_306_residues
MVRNLFFHFMKDIDLKLIEIFCYVYEYKSVTKASSELNMSQSTISFHMKNLETQLGQKLFYRKGKTLIPTAFADKLYEYA
TELTNFKRRMLEDITKFSGKNGGVIRIGASSIPGNYLLPQLLGEFIENFKGYVNVELRVSDSQDIYEKVINGDVDLGIIG
YLPRTNKVDAIKFYTDRILIVGNPELEDKVYTLEELINLPLVIREVGSGTRSIVEDKLREKGLSLKEMNIVAVCNSNEAV
KNTLKYVKGFSFLSSYVVKDDKFLIKLKVKNFDDITRQFYLIRDKKRPLPFLTQELIKFLIKDIYV
>Mature_306_residues
MVRNLFFHFMKDIDLKLIEIFCYVYEYKSVTKASSELNMSQSTISFHMKNLETQLGQKLFYRKGKTLIPTAFADKLYEYA
TELTNFKRRMLEDITKFSGKNGGVIRIGASSIPGNYLLPQLLGEFIENFKGYVNVELRVSDSQDIYEKVINGDVDLGIIG
YLPRTNKVDAIKFYTDRILIVGNPELEDKVYTLEELINLPLVIREVGSGTRSIVEDKLREKGLSLKEMNIVAVCNSNEAV
KNTLKYVKGFSFLSSYVVKDDKFLIKLKVKNFDDITRQFYLIRDKKRPLPFLTQELIKFLIKDIYV

Specific function: Activates transcription of the cmpABCD operon under carbon dioxide-limited conditions. Specifically binds to the cmpR- cmpA intergenic region [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788481, Length=251, Percent_Identity=32.2709163346614, Blast_Score=120, Evalue=9e-29,
Organism=Escherichia coli, GI1788748, Length=290, Percent_Identity=22.7586206896552, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1788296, Length=204, Percent_Identity=27.4509803921569, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI87081766, Length=307, Percent_Identity=24.1042345276873, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI87082132, Length=240, Percent_Identity=23.3333333333333, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1790208, Length=148, Percent_Identity=27.027027027027, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI157672245, Length=250, Percent_Identity=24, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35410; Mature: 35410

Theoretical pI: Translated: 9.45; Mature: 9.45

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVRNLFFHFMKDIDLKLIEIFCYVYEYKSVTKASSELNMSQSTISFHMKNLETQLGQKLF
CCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
YRKGKTLIPTAFADKLYEYATELTNFKRRMLEDITKFSGKNGGVIRIGASSIPGNYLLPQ
HHCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHH
LLGEFIENFKGYVNVELRVSDSQDIYEKVINGDVDLGIIGYLPRTNKVDAIKFYTDRILI
HHHHHHHCCCCEEEEEEEECCCHHHHHHHHCCCCCEEEEEECCCCCCCCEEEEEEEEEEE
VGNPELEDKVYTLEELINLPLVIREVGSGTRSIVEDKLREKGLSLKEMNIVAVCNSNEAV
ECCCCCCHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHCCCCEEHEEEEEEECCCHHH
KNTLKYVKGFSFLSSYVVKDDKFLIKLKVKNFDDITRQFYLIRDKKRPLPFLTQELIKFL
HHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCHHHHHHEEEEECCCCCCCHHHHHHHHHH
IKDIYV
HHHHCC
>Mature Secondary Structure
MVRNLFFHFMKDIDLKLIEIFCYVYEYKSVTKASSELNMSQSTISFHMKNLETQLGQKLF
CCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
YRKGKTLIPTAFADKLYEYATELTNFKRRMLEDITKFSGKNGGVIRIGASSIPGNYLLPQ
HHCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHH
LLGEFIENFKGYVNVELRVSDSQDIYEKVINGDVDLGIIGYLPRTNKVDAIKFYTDRILI
HHHHHHHCCCCEEEEEEEECCCHHHHHHHHCCCCCEEEEEECCCCCCCCEEEEEEEEEEE
VGNPELEDKVYTLEELINLPLVIREVGSGTRSIVEDKLREKGLSLKEMNIVAVCNSNEAV
ECCCCCCHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHCCCCEEHEEEEEEECCCHHH
KNTLKYVKGFSFLSSYVVKDDKFLIKLKVKNFDDITRQFYLIRDKKRPLPFLTQELIKFL
HHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCHHHHHHEEEEECCCCCCCHHHHHHHHHH
IKDIYV
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]