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The map label for this gene is secD

Identifier: 15606286

GI number: 15606286

Start: 672190

End: 673695

Strand: Direct

Name: secD

Synonym: aq_973

Alternate gene names: 15606286

Gene position: 672190-673695 (Clockwise)

Preceding gene: 15606283

Following gene: 15606287

Centisome position: 43.33

GC content: 44.02

Gene sequence:

>1506_bases
ATGATTTTAATTATGCAGAAAAAGAACTTATGGCTTCACCTTCTTGGACTGGTAATCCTTACGCTCCTCTCTGCTTACGC
GGTTGTAAAGTACCCTATAAACCTCGGTTTAGACCTCAAAGGCGGTGTTGAATTCCTGCTCGAACCGGATTTTAGTGTTG
CAATAGAGAGAGAGTATGAAGACCTCGCGAGAAATTTAAGGGAAAAATTATCAAAGTTTAACGTTCTTGAAGTTTATGCA
ACGAAAGAGGGCGTAATAATAGAGTTACTCGATAAAAAAGAGGTAGAAAACATAAAGAAAGTTATTCAGGATATAAACCC
TAATGTAATTTTTGAAGAAGAAGGCGATAAACTCGTAGTTAAGTTTACACAAAAGTATGTTGAACAGTTAAAGGAAGACA
TAGTAAGGCAGAGTATAGAAATCATCAGGGACAGGATAGACAAGCTCGGAGTGACTCAGCCCGTAGTCACGAGAGTCGGA
AAGTACAGAATTTTGGTGGACCTTCCAGGATTTTTGGACGTTGAAAGGGCTAAGAAGATAATAGGCAGTACCGCTTCCCT
GGAGCTAAAACTCGTAATAGATGTGTCAACCGATAGAAAAGAACTCGAGAAGAAGTTAACACCCGATAGGGAAATACTTC
CGTCCAGAGATGGAAGGGAGTGGTTTCTCGTGGAAAAGGCACCTGTTATAACGGGGCAGGACTTGAAAACCGCCTACGTC
GGCGTTGATAACCTCGGACAACCTGCGGTGAACTTTGAACTTAAAGGAGAGGCTGCGGAGAAGTTCGGAAAGTTTACAGA
ACAAAATATAGGAAAGAGACTCGCCATAGTTCTGGATAGAAAGGTTGTCTCCGCACCCGTGATAAGGAGTAAGATTTCGG
ACAGAGGACAAATAACCGGAAACTTCACGGCTCAGGAGGCGAGAGACCTCGCCCTCATACTAAGGACTGGCAGCCTCCCC
TCACCCCTCAAGTTCCTTCAGGAAAAGATAGTTGGGCCTTCTCTCGGAAAGGACGCAATAGAGCAGGGGATAAAGGCGGG
CATTTTAGCGATAATACTTCTTGCCGTGGTTCTGATAGCACGCTACAAAACTGCCGGAATTACCGCAAACATTTCCATAT
TCCTGAACGTCCTTTTCCTCCTTGCGAGCATGGCTTTCCTCGGGGCTACCCTCACCCTCCCGGGTATAGCGGGGATAATC
CTGAACATGGGTATAGCCGTGGACTCAAACGTCCTCATCTTTGAAAGGGTAAAAGAGGAACTGAGACTGGGAAACACCGT
TTCAAAAGCTATAGAACTTGGGTTCAAGAGAACTTTAAGTGCGGTTTGGGACACACACGTTACGCTTCTTGTAGCTTCCG
TTATACTCTTTCAATTTGGGAGCGGTCCCGTAAAAGGTTTTGCAACGACTCTTGCCCTAGGAACTATAGCTAGTTTTATA
TCAAACGTCTACTACGCAAAGGTGTTTTTAGATTTGCTTAACTCCCTAAAAATCCTAAAAATATGA

Upstream 100 bases:

>100_bases
CGTGAGCGGGTCAACTACCTGAGTACAGGATACGATAAAAATGAACAAAGCTGATATAAGAGCTCTTACCCTCATCAATA
ATTAGGTTAGCACTTTATGT

Downstream 100 bases:

>100_bases
AATTAATCATTCTTTCCTTTTCCCTCAGGTTCTAACTTTTCCGTGGGAGGTGCGGTCATGTTAAAAACGCTCTTTGTACT
CCTGTTAATCATTAGCACAG

Product: protein export membrane protein SecD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 501; Mature: 501

Protein sequence:

>501_residues
MILIMQKKNLWLHLLGLVILTLLSAYAVVKYPINLGLDLKGGVEFLLEPDFSVAIEREYEDLARNLREKLSKFNVLEVYA
TKEGVIIELLDKKEVENIKKVIQDINPNVIFEEEGDKLVVKFTQKYVEQLKEDIVRQSIEIIRDRIDKLGVTQPVVTRVG
KYRILVDLPGFLDVERAKKIIGSTASLELKLVIDVSTDRKELEKKLTPDREILPSRDGREWFLVEKAPVITGQDLKTAYV
GVDNLGQPAVNFELKGEAAEKFGKFTEQNIGKRLAIVLDRKVVSAPVIRSKISDRGQITGNFTAQEARDLALILRTGSLP
SPLKFLQEKIVGPSLGKDAIEQGIKAGILAIILLAVVLIARYKTAGITANISIFLNVLFLLASMAFLGATLTLPGIAGII
LNMGIAVDSNVLIFERVKEELRLGNTVSKAIELGFKRTLSAVWDTHVTLLVASVILFQFGSGPVKGFATTLALGTIASFI
SNVYYAKVFLDLLNSLKILKI

Sequences:

>Translated_501_residues
MILIMQKKNLWLHLLGLVILTLLSAYAVVKYPINLGLDLKGGVEFLLEPDFSVAIEREYEDLARNLREKLSKFNVLEVYA
TKEGVIIELLDKKEVENIKKVIQDINPNVIFEEEGDKLVVKFTQKYVEQLKEDIVRQSIEIIRDRIDKLGVTQPVVTRVG
KYRILVDLPGFLDVERAKKIIGSTASLELKLVIDVSTDRKELEKKLTPDREILPSRDGREWFLVEKAPVITGQDLKTAYV
GVDNLGQPAVNFELKGEAAEKFGKFTEQNIGKRLAIVLDRKVVSAPVIRSKISDRGQITGNFTAQEARDLALILRTGSLP
SPLKFLQEKIVGPSLGKDAIEQGIKAGILAIILLAVVLIARYKTAGITANISIFLNVLFLLASMAFLGATLTLPGIAGII
LNMGIAVDSNVLIFERVKEELRLGNTVSKAIELGFKRTLSAVWDTHVTLLVASVILFQFGSGPVKGFATTLALGTIASFI
SNVYYAKVFLDLLNSLKILKI
>Mature_501_residues
MILIMQKKNLWLHLLGLVILTLLSAYAVVKYPINLGLDLKGGVEFLLEPDFSVAIEREYEDLARNLREKLSKFNVLEVYA
TKEGVIIELLDKKEVENIKKVIQDINPNVIFEEEGDKLVVKFTQKYVEQLKEDIVRQSIEIIRDRIDKLGVTQPVVTRVG
KYRILVDLPGFLDVERAKKIIGSTASLELKLVIDVSTDRKELEKKLTPDREILPSRDGREWFLVEKAPVITGQDLKTAYV
GVDNLGQPAVNFELKGEAAEKFGKFTEQNIGKRLAIVLDRKVVSAPVIRSKISDRGQITGNFTAQEARDLALILRTGSLP
SPLKFLQEKIVGPSLGKDAIEQGIKAGILAIILLAVVLIARYKTAGITANISIFLNVLFLLASMAFLGATLTLPGIAGII
LNMGIAVDSNVLIFERVKEELRLGNTVSKAIELGFKRTLSAVWDTHVTLLVASVILFQFGSGPVKGFATTLALGTIASFI
SNVYYAKVFLDLLNSLKILKI

Specific function: Involved in protein export

COG id: COG0342

COG function: function code U; Preprotein translocase subunit SecD

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secD/secF family. SecD subfamily

Homologues:

Organism=Escherichia coli, GI1786609, Length=500, Percent_Identity=33.4, Blast_Score=283, Evalue=2e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SECD_AQUAE (O67102)

Other databases:

- EMBL:   AE000657
- PIR:   C70384
- RefSeq:   NP_213665.1
- ProteinModelPortal:   O67102
- GeneID:   1193644
- GenomeReviews:   AE000657_GR
- KEGG:   aae:aq_973
- NMPDR:   fig|224324.1.peg.680
- HOGENOM:   HBG302175
- OMA:   ENIQNGF
- PhylomeDB:   O67102
- ProtClustDB:   CLSK2299570
- BioCyc:   AAEO224324:AQ_973-MONOMER
- InterPro:   IPR005791
- InterPro:   IPR022813
- InterPro:   IPR022646
- InterPro:   IPR022645
- TIGRFAMs:   TIGR00916
- TIGRFAMs:   TIGR01129

Pfam domain/function: PF07549 Sec_GG; PF02355 SecD_SecF

EC number: NA

Molecular weight: Translated: 55460; Mature: 55460

Theoretical pI: Translated: 9.70; Mature: 9.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xca0d6ec)-; HASH(0xc642438)-; HASH(0xb199024)-; HASH(0xd312024)-; HASH(0xc720d70)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILIMQKKNLWLHLLGLVILTLLSAYAVVKYPINLGLDLKGGVEFLLEPDFSVAIEREYE
CEEEEECCCHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCEEEECCCCCEEEHHHHH
DLARNLREKLSKFNVLEVYATKEGVIIELLDKKEVENIKKVIQDINPNVIFEEEGDKLVV
HHHHHHHHHHHHCCEEEEEECCCCEEEEECCHHHHHHHHHHHHHCCCCEEEECCCCEEHH
KFTQKYVEQLKEDIVRQSIEIIRDRIDKLGVTQPVVTRVGKYRILVDLPGFLDVERAKKI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCEEEEEECCCCCCHHHHHHH
IGSTASLELKLVIDVSTDRKELEKKLTPDREILPSRDGREWFLVEKAPVITGQDLKTAYV
HCCCCCEEEEEEEEECCCHHHHHHHCCCCCCCCCCCCCCEEEEEECCCEECCCCCCEEEE
GVDNLGQPAVNFELKGEAAEKFGKFTEQNIGKRLAIVLDRKVVSAPVIRSKISDRGQITG
CCCCCCCCCEEEEECCHHHHHHHHHHHHHHCCEEEHEECCHHHHHHHHHHHCCCCCCEEC
NFTAQEARDLALILRTGSLPSPLKFLQEKIVGPSLGKDAIEQGIKAGILAIILLAVVLIA
CCCHHHHHCEEEEEECCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RYKTAGITANISIFLNVLFLLASMAFLGATLTLPGIAGIILNMGIAVDSNVLIFERVKEE
HHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCHHHHHHHHH
LRLGNTVSKAIELGFKRTLSAVWDTHVTLLVASVILFQFGSGPVKGFATTLALGTIASFI
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
SNVYYAKVFLDLLNSLKILKI
HHHHHHHHHHHHHCCCCCCCH
>Mature Secondary Structure
MILIMQKKNLWLHLLGLVILTLLSAYAVVKYPINLGLDLKGGVEFLLEPDFSVAIEREYE
CEEEEECCCHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCEEEECCCCCEEEHHHHH
DLARNLREKLSKFNVLEVYATKEGVIIELLDKKEVENIKKVIQDINPNVIFEEEGDKLVV
HHHHHHHHHHHHCCEEEEEECCCCEEEEECCHHHHHHHHHHHHHCCCCEEEECCCCEEHH
KFTQKYVEQLKEDIVRQSIEIIRDRIDKLGVTQPVVTRVGKYRILVDLPGFLDVERAKKI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCEEEEEECCCCCCHHHHHHH
IGSTASLELKLVIDVSTDRKELEKKLTPDREILPSRDGREWFLVEKAPVITGQDLKTAYV
HCCCCCEEEEEEEEECCCHHHHHHHCCCCCCCCCCCCCCEEEEEECCCEECCCCCCEEEE
GVDNLGQPAVNFELKGEAAEKFGKFTEQNIGKRLAIVLDRKVVSAPVIRSKISDRGQITG
CCCCCCCCCEEEEECCHHHHHHHHHHHHHHCCEEEHEECCHHHHHHHHHHHCCCCCCEEC
NFTAQEARDLALILRTGSLPSPLKFLQEKIVGPSLGKDAIEQGIKAGILAIILLAVVLIA
CCCHHHHHCEEEEEECCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RYKTAGITANISIFLNVLFLLASMAFLGATLTLPGIAGIILNMGIAVDSNVLIFERVKEE
HHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCHHHHHHHHH
LRLGNTVSKAIELGFKRTLSAVWDTHVTLLVASVILFQFGSGPVKGFATTLALGTIASFI
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
SNVYYAKVFLDLLNSLKILKI
HHHHHHHHHHHHHCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9537320