| Definition | Aquifex aeolicus VF5, complete genome. |
|---|---|
| Accession | NC_000918 |
| Length | 1,551,335 |
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The map label for this gene is ftsH
Identifier: 15606261
GI number: 15606261
Start: 645833
End: 647737
Strand: Direct
Name: ftsH
Synonym: aq_936
Alternate gene names: 15606261
Gene position: 645833-647737 (Clockwise)
Preceding gene: 15606257
Following gene: 15606262
Centisome position: 41.63
GC content: 46.72
Gene sequence:
>1905_bases ATGAACGCGTTGAAAAACTTCTTTATATGGGCAATCATTATCGGAGCTGCGATAGTAGCCTTTAACCTATTTGAAGGAAA AAGAGAATTTACCACGAAGGTTTCCTTAAACGAAGTAGTTAAGCTCGTTGAGGAAGGTAAGGTAAGTTACGCGGAGGTAA GGGGAAACACGGCGATAATTCAAACTAAAGACGGACAAAAACTGGAGGTGACTCTCCCACCTAACACGAACTTAGTTGAC AAAATGGTTGAGAAAGGTGTAAGGGTTGAAGTTGCAAACCCAGAACCGCCCGGAGGGTGGCTCGTAAACGTATTCCTCTC ATGGCTTCCAATACTCTTCTTTATCGGTATATGGATATTCCTCCTCAGGCAGATGTCGGGGGGTGGAAACGTAAACAGGG CCTTTAACTTCGGAAAGAGCAGGGCGAAGGTTTACATAGAGGAAAAACCGAAGGTAACTTTCAAGGACGTTGCAGGAATA GAAGAAGTAAAGGAAGAAGTAAAGGAAATTATTGAATACCTGAAAGACCCCGTTAAGTTCCAGAAGCTCGGCGGAAGACC TCCCAAGGGAGTTCTCCTTTACGGTGAGCCAGGTGTGGGTAAAACGCTCCTTGCGAAAGCTATCGCGGGCGAGGCTCACG TTCCCTTCATCTCGGTCTCTGGTTCTGACTTCGTTGAGATGTTCGTCGGTGTAGGAGCCGCACGGGTAAGGGACCTTTTT GAAACCGCAAAGAAGCACGCTCCCTGCATAATCTTTATAGACGAGATTGACGCGGTAGGAAGGGCAAGGGGAGCTATTCC CGTAGGCGGTGGACACGATGAGAGAGAACAAACCTTAAACCAGCTTCTCGTTGAAATGGACGGCTTTGACACCTCAGACG GTATTATCGTAATCGCCGCAACCAACAGACCAGACATCTTAGACCCGGCTCTTTTAAGGCCCGGACGTTTTGACAGGCAG ATATTTATACCCAAACCTGACGTAAGAGGTAGGTACGAAATACTCAAAGTTCATGCGAGGAACAAGAAACTCGCTAAGGA CGTTGACCTTGAGTTTGTGGCGAGGGCAACCCCGGGCTTTACGGGAGCGGACCTTGAAAACCTCCTAAACGAAGCGGCAT TACTCGCGGCAAGGAAAGGTAAAGAAGAGATAACTATGGAAGAAATAGAAGAAGCCCTAGACAGGATTACTATGGGACTA GAAAGAAAGGGAATGACCATATCGCCAAAAGAAAAGGAGAAGATAGCTATACACGAAGCCGGACACGCCCTCATGGGACT CGTCTCCGATGACGATGACAAGGTTCACAAGATATCCATAATCCCGAGGGGTATGGCTCTGGGAGTAACGCAACAACTTC CCATAGAAGACAAGCATATATACGACAAAAAGGATCTCTACAACAAGATACTGGTGCTTCTGGGCGGAAGGGCTGCGGAA GAGGTATTCTTCGGAAAAGATGGAATCACTACGGGAGCAGAAAATGACCTTCAGAGAGCAACGGACCTCGCTTACAGAAT GGTTTCCATGTGGGGTATGAGCGATAAGGTCGGTCCGATAGCTATAAGGAGGGTGGCAAATCCCTTCCTCGGAGGAATGA CCACAGCGGTAGACACAAGCCCTGACCTTTTAAGGGAAATAGACGAAGAGGTAAAGAGGATTATTACGGAACAGTATGAA AAGGCTAAAGCTATAGTGGAGGAATACAAAGAACCCTTGAAAGCCGTGGTCAAGAAGCTACTTGAGAAGGAAACGATAAC CTGCGAGGAGTTCGTAGAAGTGTTCAAGCTCTACGGTATAGAGCTTAAAGACAAGTGTAAGAAAGAGGAACTCTTTGACA AAGACAGGAAATCTGAGGAAAATAAAGAACTTAAATCTGAAGAAGTTAAGGAGGAGGTAGTCTGA
Upstream 100 bases:
>100_bases GCTCCAGGACTTCATAATAAGAATATTTAAACCTGCCCTGCGGTATTGCAAACTTTTTGCAGTTTAACTATTTTTTAAAA GTAATCTTCAGGAGGAGGTC
Downstream 100 bases:
>100_bases TGGGAATGACTATAACCGAGAAGATTCTGGCGGAACACGCTGGTAAGAAGGAAGTCCACCCCGGAGAACTCATAACTGCA AAGATAGACCTCGCAATGGC
Product: cell division protein FtsH
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 634; Mature: 634
Protein sequence:
>634_residues MNALKNFFIWAIIIGAAIVAFNLFEGKREFTTKVSLNEVVKLVEEGKVSYAEVRGNTAIIQTKDGQKLEVTLPPNTNLVD KMVEKGVRVEVANPEPPGGWLVNVFLSWLPILFFIGIWIFLLRQMSGGGNVNRAFNFGKSRAKVYIEEKPKVTFKDVAGI EEVKEEVKEIIEYLKDPVKFQKLGGRPPKGVLLYGEPGVGKTLLAKAIAGEAHVPFISVSGSDFVEMFVGVGAARVRDLF ETAKKHAPCIIFIDEIDAVGRARGAIPVGGGHDEREQTLNQLLVEMDGFDTSDGIIVIAATNRPDILDPALLRPGRFDRQ IFIPKPDVRGRYEILKVHARNKKLAKDVDLEFVARATPGFTGADLENLLNEAALLAARKGKEEITMEEIEEALDRITMGL ERKGMTISPKEKEKIAIHEAGHALMGLVSDDDDKVHKISIIPRGMALGVTQQLPIEDKHIYDKKDLYNKILVLLGGRAAE EVFFGKDGITTGAENDLQRATDLAYRMVSMWGMSDKVGPIAIRRVANPFLGGMTTAVDTSPDLLREIDEEVKRIITEQYE KAKAIVEEYKEPLKAVVKKLLEKETITCEEFVEVFKLYGIELKDKCKKEELFDKDRKSEENKELKSEEVKEEVV
Sequences:
>Translated_634_residues MNALKNFFIWAIIIGAAIVAFNLFEGKREFTTKVSLNEVVKLVEEGKVSYAEVRGNTAIIQTKDGQKLEVTLPPNTNLVD KMVEKGVRVEVANPEPPGGWLVNVFLSWLPILFFIGIWIFLLRQMSGGGNVNRAFNFGKSRAKVYIEEKPKVTFKDVAGI EEVKEEVKEIIEYLKDPVKFQKLGGRPPKGVLLYGEPGVGKTLLAKAIAGEAHVPFISVSGSDFVEMFVGVGAARVRDLF ETAKKHAPCIIFIDEIDAVGRARGAIPVGGGHDEREQTLNQLLVEMDGFDTSDGIIVIAATNRPDILDPALLRPGRFDRQ IFIPKPDVRGRYEILKVHARNKKLAKDVDLEFVARATPGFTGADLENLLNEAALLAARKGKEEITMEEIEEALDRITMGL ERKGMTISPKEKEKIAIHEAGHALMGLVSDDDDKVHKISIIPRGMALGVTQQLPIEDKHIYDKKDLYNKILVLLGGRAAE EVFFGKDGITTGAENDLQRATDLAYRMVSMWGMSDKVGPIAIRRVANPFLGGMTTAVDTSPDLLREIDEEVKRIITEQYE KAKAIVEEYKEPLKAVVKKLLEKETITCEEFVEVFKLYGIELKDKCKKEELFDKDRKSEENKELKSEEVKEEVV >Mature_634_residues MNALKNFFIWAIIIGAAIVAFNLFEGKREFTTKVSLNEVVKLVEEGKVSYAEVRGNTAIIQTKDGQKLEVTLPPNTNLVD KMVEKGVRVEVANPEPPGGWLVNVFLSWLPILFFIGIWIFLLRQMSGGGNVNRAFNFGKSRAKVYIEEKPKVTFKDVAGI EEVKEEVKEIIEYLKDPVKFQKLGGRPPKGVLLYGEPGVGKTLLAKAIAGEAHVPFISVSGSDFVEMFVGVGAARVRDLF ETAKKHAPCIIFIDEIDAVGRARGAIPVGGGHDEREQTLNQLLVEMDGFDTSDGIIVIAATNRPDILDPALLRPGRFDRQ IFIPKPDVRGRYEILKVHARNKKLAKDVDLEFVARATPGFTGADLENLLNEAALLAARKGKEEITMEEIEEALDRITMGL ERKGMTISPKEKEKIAIHEAGHALMGLVSDDDDKVHKISIIPRGMALGVTQQLPIEDKHIYDKKDLYNKILVLLGGRAAE EVFFGKDGITTGAENDLQRATDLAYRMVSMWGMSDKVGPIAIRRVANPFLGGMTTAVDTSPDLLREIDEEVKRIITEQYE KAKAIVEEYKEPLKAVVKKLLEKETITCEEFVEVFKLYGIELKDKCKKEELFDKDRKSEENKELKSEEVKEEVV
Specific function: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
COG id: COG0465
COG function: function code O; ATP-dependent Zn proteases
Gene ontology:
Cell location: Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: In the C-terminal section; belongs to the peptidase M41 family
Homologues:
Organism=Homo sapiens, GI300192933, Length=619, Percent_Identity=43.9418416801292, Blast_Score=454, Evalue=1e-127, Organism=Homo sapiens, GI7657689, Length=442, Percent_Identity=47.9638009049774, Blast_Score=406, Evalue=1e-113, Organism=Homo sapiens, GI21327685, Length=442, Percent_Identity=47.9638009049774, Blast_Score=406, Evalue=1e-113, Organism=Homo sapiens, GI4507173, Length=478, Percent_Identity=43.3054393305439, Blast_Score=386, Evalue=1e-107, Organism=Homo sapiens, GI6005942, Length=230, Percent_Identity=49.5652173913044, Blast_Score=230, Evalue=4e-60, Organism=Homo sapiens, GI4506209, Length=255, Percent_Identity=45.8823529411765, Blast_Score=226, Evalue=7e-59, Organism=Homo sapiens, GI24497435, Length=267, Percent_Identity=43.8202247191011, Blast_Score=222, Evalue=7e-58, Organism=Homo sapiens, GI21361144, Length=256, Percent_Identity=43.359375, Blast_Score=212, Evalue=9e-55, Organism=Homo sapiens, GI195539395, Length=252, Percent_Identity=43.2539682539683, Blast_Score=208, Evalue=1e-53, Organism=Homo sapiens, GI24430151, Length=252, Percent_Identity=41.2698412698413, Blast_Score=206, Evalue=4e-53, Organism=Homo sapiens, GI5729991, Length=248, Percent_Identity=43.5483870967742, Blast_Score=195, Evalue=9e-50, Organism=Homo sapiens, GI89064750, Length=248, Percent_Identity=43.5483870967742, Blast_Score=195, Evalue=1e-49, Organism=Homo sapiens, GI24430155, Length=248, Percent_Identity=43.5483870967742, Blast_Score=195, Evalue=1e-49, Organism=Homo sapiens, GI45643123, Length=284, Percent_Identity=38.3802816901408, Blast_Score=193, Evalue=5e-49, Organism=Homo sapiens, GI45643125, Length=284, Percent_Identity=38.3802816901408, Blast_Score=192, Evalue=6e-49, Organism=Homo sapiens, GI229577436, Length=267, Percent_Identity=41.9475655430712, Blast_Score=188, Evalue=1e-47, Organism=Homo sapiens, GI157671927, Length=228, Percent_Identity=41.6666666666667, Blast_Score=186, Evalue=4e-47, Organism=Homo sapiens, GI4505725, Length=234, Percent_Identity=42.7350427350427, Blast_Score=182, Evalue=6e-46, Organism=Homo sapiens, GI40806173, Length=173, Percent_Identity=53.1791907514451, Blast_Score=175, Evalue=2e-43, Organism=Homo sapiens, GI5901990, Length=251, Percent_Identity=40.2390438247012, Blast_Score=168, Evalue=2e-41, Organism=Homo sapiens, GI194018488, Length=263, Percent_Identity=40.3041825095057, Blast_Score=162, Evalue=7e-40, Organism=Homo sapiens, GI24497618, Length=291, Percent_Identity=36.426116838488, Blast_Score=160, Evalue=4e-39, Organism=Homo sapiens, GI14149767, Length=251, Percent_Identity=37.8486055776892, Blast_Score=159, Evalue=6e-39, Organism=Homo sapiens, GI62177112, Length=251, Percent_Identity=37.8486055776892, Blast_Score=159, Evalue=6e-39, Organism=Homo sapiens, GI153792536, Length=292, Percent_Identity=36.3013698630137, Blast_Score=157, Evalue=2e-38, Organism=Homo sapiens, GI31742536, Length=233, Percent_Identity=36.9098712446352, Blast_Score=150, Evalue=2e-36, Organism=Homo sapiens, GI112789543, Length=233, Percent_Identity=36.9098712446352, Blast_Score=150, Evalue=2e-36, Organism=Homo sapiens, GI7019569, Length=240, Percent_Identity=37.0833333333333, Blast_Score=150, Evalue=3e-36, Organism=Homo sapiens, GI17865802, Length=238, Percent_Identity=37.8151260504202, Blast_Score=146, Evalue=5e-35, Organism=Homo sapiens, GI31377644, Length=249, Percent_Identity=38.1526104417671, Blast_Score=145, Evalue=1e-34, Organism=Homo sapiens, GI226371754, Length=246, Percent_Identity=36.5853658536585, Blast_Score=145, Evalue=2e-34, Organism=Homo sapiens, GI156564401, Length=234, Percent_Identity=38.8888888888889, Blast_Score=135, Evalue=2e-31, Organism=Homo sapiens, GI310125280, Length=234, Percent_Identity=38.4615384615385, Blast_Score=131, Evalue=2e-30, Organism=Homo sapiens, GI310125282, Length=234, Percent_Identity=38.4615384615385, Blast_Score=130, Evalue=5e-30, Organism=Homo sapiens, GI11875211, Length=273, Percent_Identity=34.0659340659341, Blast_Score=129, Evalue=1e-29, Organism=Homo sapiens, GI40806170, Length=273, Percent_Identity=34.0659340659341, Blast_Score=129, Evalue=1e-29, Organism=Homo sapiens, GI64084766, Length=275, Percent_Identity=27.6363636363636, Blast_Score=104, Evalue=2e-22, Organism=Homo sapiens, GI116292174, Length=255, Percent_Identity=27.4509803921569, Blast_Score=84, Evalue=3e-16, Organism=Escherichia coli, GI1789568, Length=590, Percent_Identity=51.3559322033898, Blast_Score=584, Evalue=1e-168, Organism=Caenorhabditis elegans, GI71994521, Length=459, Percent_Identity=50.1089324618736, Blast_Score=427, Evalue=1e-120, Organism=Caenorhabditis elegans, GI17554264, Length=438, Percent_Identity=48.8584474885845, Blast_Score=402, Evalue=1e-112, Organism=Caenorhabditis elegans, GI115534323, Length=448, Percent_Identity=44.4196428571429, Blast_Score=360, Evalue=2e-99, Organism=Caenorhabditis elegans, GI17532375, Length=274, Percent_Identity=43.7956204379562, Blast_Score=232, Evalue=6e-61, Organism=Caenorhabditis elegans, GI17554786, Length=267, Percent_Identity=44.1947565543071, Blast_Score=227, Evalue=1e-59, Organism=Caenorhabditis elegans, GI17531535, Length=275, Percent_Identity=45.0909090909091, Blast_Score=225, Evalue=6e-59, Organism=Caenorhabditis elegans, GI25144278, Length=267, Percent_Identity=44.1947565543071, Blast_Score=223, Evalue=2e-58, Organism=Caenorhabditis elegans, GI25144281, Length=267, Percent_Identity=44.1947565543071, Blast_Score=223, Evalue=2e-58, Organism=Caenorhabditis elegans, GI17563248, Length=265, Percent_Identity=43.7735849056604, Blast_Score=223, Evalue=3e-58, Organism=Caenorhabditis elegans, GI17563250, Length=252, Percent_Identity=42.0634920634921, Blast_Score=208, Evalue=8e-54, Organism=Caenorhabditis elegans, GI17508701, Length=259, Percent_Identity=42.4710424710425, Blast_Score=207, Evalue=1e-53, Organism=Caenorhabditis elegans, GI71987364, Length=256, Percent_Identity=41.796875, Blast_Score=204, Evalue=1e-52, Organism=Caenorhabditis elegans, GI71987372, Length=256, Percent_Identity=41.796875, Blast_Score=204, Evalue=1e-52, Organism=Caenorhabditis elegans, GI17505546, Length=260, Percent_Identity=42.6923076923077, Blast_Score=202, Evalue=5e-52, Organism=Caenorhabditis elegans, GI17554784, Length=248, Percent_Identity=43.9516129032258, Blast_Score=191, Evalue=1e-48, Organism=Caenorhabditis elegans, GI17508053, Length=253, Percent_Identity=40.7114624505929, Blast_Score=185, Evalue=7e-47, Organism=Caenorhabditis elegans, GI17537217, Length=234, Percent_Identity=42.3076923076923, Blast_Score=171, Evalue=2e-42, Organism=Caenorhabditis elegans, GI25153574, Length=249, Percent_Identity=37.3493975903614, Blast_Score=161, Evalue=1e-39, Organism=Caenorhabditis elegans, GI193209502, Length=248, Percent_Identity=37.0967741935484, Blast_Score=157, Evalue=1e-38, Organism=Caenorhabditis elegans, GI17562804, Length=233, Percent_Identity=38.1974248927039, Blast_Score=156, Evalue=3e-38, Organism=Caenorhabditis elegans, GI86561515, Length=240, Percent_Identity=37.5, Blast_Score=151, Evalue=9e-37, Organism=Caenorhabditis elegans, GI193206116, Length=246, Percent_Identity=38.2113821138211, Blast_Score=150, Evalue=2e-36, Organism=Caenorhabditis elegans, GI193206114, Length=246, Percent_Identity=38.2113821138211, Blast_Score=150, Evalue=2e-36, Organism=Caenorhabditis elegans, GI133931034, Length=246, Percent_Identity=38.2113821138211, Blast_Score=150, Evalue=2e-36, Organism=Caenorhabditis elegans, GI17541224, Length=232, Percent_Identity=37.5, Blast_Score=137, Evalue=2e-32, Organism=Caenorhabditis elegans, GI17570397, Length=165, Percent_Identity=44.8484848484849, Blast_Score=137, Evalue=2e-32, Organism=Caenorhabditis elegans, GI32566590, Length=165, Percent_Identity=44.8484848484849, Blast_Score=137, Evalue=2e-32, Organism=Caenorhabditis elegans, GI17541226, Length=232, Percent_Identity=37.5, Blast_Score=137, Evalue=2e-32, Organism=Caenorhabditis elegans, GI25146157, Length=272, Percent_Identity=36.0294117647059, Blast_Score=132, Evalue=5e-31, Organism=Caenorhabditis elegans, GI133901662, Length=210, Percent_Identity=40, Blast_Score=132, Evalue=7e-31, Organism=Caenorhabditis elegans, GI133901658, Length=210, Percent_Identity=40, Blast_Score=132, Evalue=8e-31, Organism=Caenorhabditis elegans, GI17508421, Length=244, Percent_Identity=37.2950819672131, Blast_Score=127, Evalue=3e-29, Organism=Caenorhabditis elegans, GI32563584, Length=244, Percent_Identity=37.2950819672131, Blast_Score=126, Evalue=3e-29, Organism=Caenorhabditis elegans, GI17560432, Length=230, Percent_Identity=34.7826086956522, Blast_Score=119, Evalue=6e-27, Organism=Saccharomyces cerevisiae, GI6323736, Length=509, Percent_Identity=45.5795677799607, Blast_Score=424, Evalue=1e-119, Organism=Saccharomyces cerevisiae, GI6320854, Length=515, Percent_Identity=45.4368932038835, Blast_Score=419, Evalue=1e-118, Organism=Saccharomyces cerevisiae, GI6325281, Length=449, Percent_Identity=45.2115812917595, Blast_Score=382, Evalue=1e-107, Organism=Saccharomyces cerevisiae, GI6321390, Length=256, Percent_Identity=45.3125, Blast_Score=224, Evalue=4e-59, Organism=Saccharomyces cerevisiae, GI6322704, Length=265, Percent_Identity=43.3962264150943, Blast_Score=222, Evalue=1e-58, Organism=Saccharomyces cerevisiae, GI6320077, Length=265, Percent_Identity=43.0188679245283, Blast_Score=212, Evalue=1e-55, Organism=Saccharomyces cerevisiae, GI6324833, Length=251, Percent_Identity=44.6215139442231, Blast_Score=212, Evalue=2e-55, Organism=Saccharomyces cerevisiae, GI6324691, Length=271, Percent_Identity=40.9594095940959, Blast_Score=207, Evalue=4e-54, Organism=Saccharomyces cerevisiae, GI6320197, Length=252, Percent_Identity=39.6825396825397, Blast_Score=203, Evalue=6e-53, Organism=Saccharomyces cerevisiae, GI6320602, Length=247, Percent_Identity=43.7246963562753, Blast_Score=194, Evalue=3e-50, Organism=Saccharomyces cerevisiae, GI6322994, Length=250, Percent_Identity=38.8, Blast_Score=178, Evalue=2e-45, Organism=Saccharomyces cerevisiae, GI6321709, Length=244, Percent_Identity=40.5737704918033, Blast_Score=176, Evalue=1e-44, Organism=Saccharomyces cerevisiae, GI6323429, Length=257, Percent_Identity=40.4669260700389, Blast_Score=175, Evalue=2e-44, Organism=Saccharomyces cerevisiae, GI6324000, Length=234, Percent_Identity=43.5897435897436, Blast_Score=174, Evalue=5e-44, Organism=Saccharomyces cerevisiae, GI6322651, Length=266, Percent_Identity=34.9624060150376, Blast_Score=167, Evalue=4e-42, Organism=Saccharomyces cerevisiae, GI6325431, Length=258, Percent_Identity=39.1472868217054, Blast_Score=154, Evalue=5e-38, Organism=Saccharomyces cerevisiae, GI6325183, Length=238, Percent_Identity=35.7142857142857, Blast_Score=143, Evalue=1e-34, Organism=Saccharomyces cerevisiae, GI6321465, Length=234, Percent_Identity=35.8974358974359, Blast_Score=137, Evalue=4e-33, Organism=Saccharomyces cerevisiae, GI6319554, Length=284, Percent_Identity=33.8028169014084, Blast_Score=135, Evalue=3e-32, Organism=Saccharomyces cerevisiae, GI6320887, Length=248, Percent_Identity=32.6612903225806, Blast_Score=122, Evalue=2e-28, Organism=Saccharomyces cerevisiae, GI6320583, Length=189, Percent_Identity=28.5714285714286, Blast_Score=72, Evalue=3e-13, Organism=Drosophila melanogaster, GI28574878, Length=527, Percent_Identity=45.73055028463, Blast_Score=450, Evalue=1e-126, Organism=Drosophila melanogaster, GI24665814, Length=527, Percent_Identity=45.73055028463, Blast_Score=450, Evalue=1e-126, Organism=Drosophila melanogaster, GI24658770, Length=505, Percent_Identity=44.5544554455446, Blast_Score=413, Evalue=1e-115, Organism=Drosophila melanogaster, GI24639391, Length=462, Percent_Identity=45.8874458874459, Blast_Score=404, Evalue=1e-113, Organism=Drosophila melanogaster, GI17137560, Length=246, Percent_Identity=47.1544715447154, Blast_Score=234, Evalue=1e-61, Organism=Drosophila melanogaster, GI161076486, Length=246, Percent_Identity=47.1544715447154, Blast_Score=234, Evalue=2e-61, Organism=Drosophila melanogaster, GI161076488, Length=246, Percent_Identity=47.1544715447154, Blast_Score=234, Evalue=2e-61, Organism=Drosophila melanogaster, GI24651451, Length=265, Percent_Identity=44.1509433962264, Blast_Score=229, Evalue=7e-60, Organism=Drosophila melanogaster, GI19920408, Length=266, Percent_Identity=44.7368421052632, Blast_Score=226, Evalue=4e-59, Organism=Drosophila melanogaster, GI17137738, Length=255, Percent_Identity=45.0980392156863, Blast_Score=220, Evalue=2e-57, Organism=Drosophila melanogaster, GI17738151, Length=252, Percent_Identity=42.8571428571429, Blast_Score=210, Evalue=2e-54, Organism=Drosophila melanogaster, GI45554047, Length=165, Percent_Identity=61.2121212121212, Blast_Score=209, Evalue=5e-54, Organism=Drosophila melanogaster, GI24640100, Length=253, Percent_Identity=43.4782608695652, Blast_Score=207, Evalue=1e-53, Organism=Drosophila melanogaster, GI24649446, Length=248, Percent_Identity=42.3387096774194, Blast_Score=206, Evalue=5e-53, Organism=Drosophila melanogaster, GI24652279, Length=207, Percent_Identity=48.3091787439614, Blast_Score=202, Evalue=5e-52, Organism=Drosophila melanogaster, GI24660075, Length=235, Percent_Identity=44.6808510638298, Blast_Score=201, Evalue=1e-51, Organism=Drosophila melanogaster, GI281365776, Length=235, Percent_Identity=44.6808510638298, Blast_Score=201, Evalue=1e-51, Organism=Drosophila melanogaster, GI24663015, Length=254, Percent_Identity=43.3070866141732, Blast_Score=201, Evalue=1e-51, Organism=Drosophila melanogaster, GI45552965, Length=235, Percent_Identity=44.6808510638298, Blast_Score=201, Evalue=1e-51, Organism=Drosophila melanogaster, GI18860063, Length=237, Percent_Identity=45.1476793248945, Blast_Score=197, Evalue=2e-50, Organism=Drosophila melanogaster, GI281361487, Length=246, Percent_Identity=41.4634146341463, Blast_Score=194, Evalue=2e-49, Organism=Drosophila melanogaster, GI19921202, Length=253, Percent_Identity=38.7351778656126, Blast_Score=194, Evalue=2e-49, Organism=Drosophila melanogaster, GI24656825, Length=248, Percent_Identity=39.1129032258064, Blast_Score=176, Evalue=4e-44, Organism=Drosophila melanogaster, GI24656820, Length=248, Percent_Identity=39.1129032258064, Blast_Score=176, Evalue=5e-44, Organism=Drosophila melanogaster, GI281363136, Length=237, Percent_Identity=40.5063291139241, Blast_Score=175, Evalue=9e-44, Organism=Drosophila melanogaster, GI78707192, Length=237, Percent_Identity=40.5063291139241, Blast_Score=175, Evalue=9e-44, Organism=Drosophila melanogaster, GI18859657, Length=238, Percent_Identity=41.1764705882353, Blast_Score=160, Evalue=2e-39, Organism=Drosophila melanogaster, GI21355121, Length=284, Percent_Identity=33.8028169014084, Blast_Score=155, Evalue=1e-37, Organism=Drosophila melanogaster, GI24644145, Length=251, Percent_Identity=36.6533864541833, Blast_Score=153, Evalue=3e-37, Organism=Drosophila melanogaster, GI281360136, Length=250, Percent_Identity=34.4, Blast_Score=142, Evalue=6e-34, Organism=Drosophila melanogaster, GI24644411, Length=250, Percent_Identity=34.4, Blast_Score=142, Evalue=6e-34, Organism=Drosophila melanogaster, GI281360144, Length=250, Percent_Identity=34.4, Blast_Score=142, Evalue=6e-34, Organism=Drosophila melanogaster, GI281360140, Length=250, Percent_Identity=34.4, Blast_Score=142, Evalue=6e-34, Organism=Drosophila melanogaster, GI281360142, Length=238, Percent_Identity=35.2941176470588, Blast_Score=141, Evalue=1e-33, Organism=Drosophila melanogaster, GI21357333, Length=238, Percent_Identity=35.2941176470588, Blast_Score=141, Evalue=1e-33, Organism=Drosophila melanogaster, GI281360146, Length=238, Percent_Identity=35.2941176470588, Blast_Score=141, Evalue=1e-33, Organism=Drosophila melanogaster, GI281360138, Length=238, Percent_Identity=35.2941176470588, Blast_Score=141, Evalue=1e-33, Organism=Drosophila melanogaster, GI20129529, Length=277, Percent_Identity=35.0180505415162, Blast_Score=141, Evalue=1e-33, Organism=Drosophila melanogaster, GI20129423, Length=233, Percent_Identity=36.0515021459227, Blast_Score=137, Evalue=2e-32, Organism=Drosophila melanogaster, GI24581396, Length=262, Percent_Identity=37.4045801526718, Blast_Score=135, Evalue=6e-32, Organism=Drosophila melanogaster, GI28573010, Length=217, Percent_Identity=40.0921658986175, Blast_Score=135, Evalue=7e-32, Organism=Drosophila melanogaster, GI17864540, Length=210, Percent_Identity=40.9523809523809, Blast_Score=135, Evalue=7e-32, Organism=Drosophila melanogaster, GI28571849, Length=250, Percent_Identity=35.2, Blast_Score=126, Evalue=5e-29, Organism=Drosophila melanogaster, GI28571847, Length=250, Percent_Identity=35.2, Blast_Score=126, Evalue=5e-29, Organism=Drosophila melanogaster, GI24639486, Length=244, Percent_Identity=30.7377049180328, Blast_Score=105, Evalue=1e-22,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): FTSH_AQUAE (O67077)
Other databases:
- EMBL: AE000657 - PIR: B70381 - RefSeq: NP_213640.1 - PDB: 2DI4 - PDBsum: 2DI4 - ProteinModelPortal: O67077 - SMR: O67077 - MEROPS: M41.001 - GeneID: 1193619 - GenomeReviews: AE000657_GR - KEGG: aae:aq_936 - NMPDR: fig|224324.1.peg.655 - HOGENOM: HBG724153 - OMA: LLEHETI - ProtClustDB: CLSK2299557 - BioCyc: AAEO224324:AQ_936-MONOMER - GO: GO:0006508 - HAMAP: MF_01458 - InterPro: IPR003593 - InterPro: IPR003959 - InterPro: IPR003960 - InterPro: IPR005936 - InterPro: IPR011546 - InterPro: IPR000642 - SMART: SM00382 - TIGRFAMs: TIGR01241
Pfam domain/function: PF00004 AAA; PF06480 FtsH_ext; PF01434 Peptidase_M41
EC number: 3.4.24.-
Molecular weight: Translated: 70687; Mature: 70687
Theoretical pI: Translated: 5.47; Mature: 5.47
Prosite motif: PS00674 AAA
Important sites: ACT_SITE 419-419
Signals:
None
Transmembrane regions:
HASH(0xc342f04)-; HASH(0xd50e5c4)-;
Cys/Met content:
0.5 %Cys (Translated Protein) 2.2 %Met (Translated Protein) 2.7 %Cys+Met (Translated Protein) 0.5 %Cys (Mature Protein) 2.2 %Met (Mature Protein) 2.7 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MNALKNFFIWAIIIGAAIVAFNLFEGKREFTTKVSLNEVVKLVEEGKVSYAEVRGNTAII CCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHCCCEEEEECCCEEEE QTKDGQKLEVTLPPNTNLVDKMVEKGVRVEVANPEPPGGWLVNVFLSWLPILFFIGIWIF EECCCCEEEEEECCCCCHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHH LLRQMSGGGNVNRAFNFGKSRAKVYIEEKPKVTFKDVAGIEEVKEEVKEIIEYLKDPVKF HHHHHCCCCCCHHHHHCCCCCEEEEEECCCCEEHHHHCCHHHHHHHHHHHHHHHHCCHHH QKLGGRPPKGVLLYGEPGVGKTLLAKAIAGEAHVPFISVSGSDFVEMFVGVGAARVRDLF HHCCCCCCCCEEEECCCCCCHHHHHHHHCCCCCCCEEEECCHHHHHHHHHCCHHHHHHHH ETAKKHAPCIIFIDEIDAVGRARGAIPVGGGHDEREQTLNQLLVEMDGFDTSDGIIVIAA HHHHHCCCEEEEEECCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEE TNRPDILDPALLRPGRFDRQIFIPKPDVRGRYEILKVHARNKKLAKDVDLEFVARATPGF CCCCCCCCHHHCCCCCCCCEEECCCCCCCCCEEEEEEECCCCHHHHHCCHHHEEECCCCC TGADLENLLNEAALLAARKGKEEITMEEIEEALDRITMGLERKGMTISPKEKEKIAIHEA CCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEHHHC GHALMGLVSDDDDKVHKISIIPRGMALGVTQQLPIEDKHIYDKKDLYNKILVLLGGRAAE CHHHEEEECCCCCCEEEEEEECCCCEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHH EVFFGKDGITTGAENDLQRATDLAYRMVSMWGMSDKVGPIAIRRVANPFLGGMTTAVDTS HHEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHCCCC PDLLREIDEEVKRIITEQYEKAKAIVEEYKEPLKAVVKKLLEKETITCEEFVEVFKLYGI HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCC ELKDKCKKEELFDKDRKSEENKELKSEEVKEEVV CHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCH >Mature Secondary Structure MNALKNFFIWAIIIGAAIVAFNLFEGKREFTTKVSLNEVVKLVEEGKVSYAEVRGNTAII CCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHCCCEEEEECCCEEEE QTKDGQKLEVTLPPNTNLVDKMVEKGVRVEVANPEPPGGWLVNVFLSWLPILFFIGIWIF EECCCCEEEEEECCCCCHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHH LLRQMSGGGNVNRAFNFGKSRAKVYIEEKPKVTFKDVAGIEEVKEEVKEIIEYLKDPVKF HHHHHCCCCCCHHHHHCCCCCEEEEEECCCCEEHHHHCCHHHHHHHHHHHHHHHHCCHHH QKLGGRPPKGVLLYGEPGVGKTLLAKAIAGEAHVPFISVSGSDFVEMFVGVGAARVRDLF HHCCCCCCCCEEEECCCCCCHHHHHHHHCCCCCCCEEEECCHHHHHHHHHCCHHHHHHHH ETAKKHAPCIIFIDEIDAVGRARGAIPVGGGHDEREQTLNQLLVEMDGFDTSDGIIVIAA HHHHHCCCEEEEEECCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEE TNRPDILDPALLRPGRFDRQIFIPKPDVRGRYEILKVHARNKKLAKDVDLEFVARATPGF CCCCCCCCHHHCCCCCCCCEEECCCCCCCCCEEEEEEECCCCHHHHHCCHHHEEECCCCC TGADLENLLNEAALLAARKGKEEITMEEIEEALDRITMGLERKGMTISPKEKEKIAIHEA CCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEHHHC GHALMGLVSDDDDKVHKISIIPRGMALGVTQQLPIEDKHIYDKKDLYNKILVLLGGRAAE CHHHEEEECCCCCCEEEEEEECCCCEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHH EVFFGKDGITTGAENDLQRATDLAYRMVSMWGMSDKVGPIAIRRVANPFLGGMTTAVDTS HHEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHCCCC PDLLREIDEEVKRIITEQYEKAKAIVEEYKEPLKAVVKKLLEKETITCEEFVEVFKLYGI HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCC ELKDKCKKEELFDKDRKSEENKELKSEEVKEEVV CHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCH
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Metalloendopeptidases [C]
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 9537320