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The map label for this gene is dapB

Identifier: 15606245

GI number: 15606245

Start: 631526

End: 632323

Strand: Direct

Name: dapB

Synonym: aq_916

Alternate gene names: 15606245

Gene position: 631526-632323 (Clockwise)

Preceding gene: 15606244

Following gene: 15606248

Centisome position: 40.71

GC content: 47.37

Gene sequence:

>798_bases
ATGAGCGTCAGGGTGGTAGTTTGTGGTGCCCTCGGTAGGATGGGAAGGAGGATAATAGAACTTGCACTTCAGGATAAAGA
TGTGGAAGTAGTCGGAGGAGTTGAACATCCGGACTGCGTACCTTCAATAGATCTGGGAGAAGCCCTTGGAAAGGAAGAAC
TGAAAGGAAAACCTCTAACGAGCAGACTCGAAGAACTCCTTCCCTACACGGATGTGGTTATAGAGTTTTCGGGAAATCCC
ACCGCGGCTGTAGGGCACGCGGAGTTAACCACCCTTGAAAAGAAGGCGATAGTTATAGGAACTACTGGATTTACGAAACA
GGAAATTGAACAGATAAAGGAGTTTTCAAAAAACGCTCCCGTTTTACTCTCACCCAATATGAGTTTGGGAGTAAACCTCC
TCTTCAAACTCGCAGAAATCGCTGCAAAGGTTTTGAAAGACAAAAACTTTGACGCGGAAATAATGGAAATACACCACAGG
TTTAAGAAGGACGCTCCGAGCGGAACGGCTATGAAACTCGCCGAAATACTCTCCGAAACTCTTGAGAAGAAGAACTTGGT
TTTCGGTAGAAAGGGAGAAGCTCCCAGAAAAGAGGACGAGATAGGCGTTATGGCTCTAAGGGGTGGAGACGTGGTAGGAG
ATCACACCGTTTACTTCTTAGGATTTGGTGAGAGGATAGAGCTCACCCACAGGGCGACGTCCAGAGATACCTTTGCAAAA
GGTGCCGTTGAAGCGGCAAAGTGGATTAAGGGGAAAGAACCCGGATTTTACACGATGTTTGACGTGCTCGGGCTCTGA

Upstream 100 bases:

>100_bases
TCAGAGTGGCTATTTACCCTTCGGTGGTACCCCCTGAGCAAGCCTCAGAAGCCGTTAAGGAACTTGAACAATTAATCTTC
GGTGAGGAAGAGGGAGAAAA

Downstream 100 bases:

>100_bases
GCCCTCTTTATATGCTTCACGTAAACGAGAACACCTTTACTTATGTTGTACAAAAAGTAAAGAGAACTTATAAGGAAGAA
AGTGGGAGGGAGAAAGTAAA

Product: dihydrodipicolinate reductase

Products: NA

Alternate protein names: DHPR

Number of amino acids: Translated: 265; Mature: 264

Protein sequence:

>265_residues
MSVRVVVCGALGRMGRRIIELALQDKDVEVVGGVEHPDCVPSIDLGEALGKEELKGKPLTSRLEELLPYTDVVIEFSGNP
TAAVGHAELTTLEKKAIVIGTTGFTKQEIEQIKEFSKNAPVLLSPNMSLGVNLLFKLAEIAAKVLKDKNFDAEIMEIHHR
FKKDAPSGTAMKLAEILSETLEKKNLVFGRKGEAPRKEDEIGVMALRGGDVVGDHTVYFLGFGERIELTHRATSRDTFAK
GAVEAAKWIKGKEPGFYTMFDVLGL

Sequences:

>Translated_265_residues
MSVRVVVCGALGRMGRRIIELALQDKDVEVVGGVEHPDCVPSIDLGEALGKEELKGKPLTSRLEELLPYTDVVIEFSGNP
TAAVGHAELTTLEKKAIVIGTTGFTKQEIEQIKEFSKNAPVLLSPNMSLGVNLLFKLAEIAAKVLKDKNFDAEIMEIHHR
FKKDAPSGTAMKLAEILSETLEKKNLVFGRKGEAPRKEDEIGVMALRGGDVVGDHTVYFLGFGERIELTHRATSRDTFAK
GAVEAAKWIKGKEPGFYTMFDVLGL
>Mature_264_residues
SVRVVVCGALGRMGRRIIELALQDKDVEVVGGVEHPDCVPSIDLGEALGKEELKGKPLTSRLEELLPYTDVVIEFSGNPT
AAVGHAELTTLEKKAIVIGTTGFTKQEIEQIKEFSKNAPVLLSPNMSLGVNLLFKLAEIAAKVLKDKNFDAEIMEIHHRF
KKDAPSGTAMKLAEILSETLEKKNLVFGRKGEAPRKEDEIGVMALRGGDVVGDHTVYFLGFGERIELTHRATSRDTFAKG
AVEAAKWIKGKEPGFYTMFDVLGL

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; second step. [C]

COG id: COG0289

COG function: function code E; Dihydrodipicolinate reductase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydrodipicolinate reductase family

Homologues:

Organism=Escherichia coli, GI1786214, Length=269, Percent_Identity=39.7769516728625, Blast_Score=174, Evalue=6e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DAPB_AQUAE (O67061)

Other databases:

- EMBL:   AE000657
- PIR:   B70379
- RefSeq:   NP_213623.1
- ProteinModelPortal:   O67061
- SMR:   O67061
- GeneID:   1193603
- GenomeReviews:   AE000657_GR
- KEGG:   aae:aq_916
- NMPDR:   fig|224324.1.peg.638
- HOGENOM:   HBG594002
- OMA:   GRMGKTL
- PhylomeDB:   O67061
- ProtClustDB:   PRK00048
- BioCyc:   AAEO224324:AQ_916-MONOMER
- BRENDA:   1.3.1.26
- GO:   GO:0005737
- GO:   GO:0005488
- HAMAP:   MF_00102
- InterPro:   IPR022663
- InterPro:   IPR000846
- InterPro:   IPR022664
- InterPro:   IPR011770
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR20836
- TIGRFAMs:   TIGR00036

Pfam domain/function: PF05173 DapB_C; PF01113 DapB_N

EC number: =1.3.1.26

Molecular weight: Translated: 28961; Mature: 28830

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: PS01298 DAPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVRVVVCGALGRMGRRIIELALQDKDVEVVGGVEHPDCVPSIDLGEALGKEELKGKPLT
CCEEEEEECHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCHHHHCCHHHHCCCCHH
SRLEELLPYTDVVIEFSGNPTAAVGHAELTTLEKKAIVIGTTGFTKQEIEQIKEFSKNAP
HHHHHHCCCEEEEEEECCCCCEEECCHHHHEECCCEEEEECCCCCHHHHHHHHHHCCCCC
VLLSPNMSLGVNLLFKLAEIAAKVLKDKNFDAEIMEIHHRFKKDAPSGTAMKLAEILSET
EEECCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
LEKKNLVFGRKGEAPRKEDEIGVMALRGGDVVGDHTVYFLGFGERIELTHRATSRDTFAK
HHHHCCEECCCCCCCCCCCCCCEEEEECCCEECCCEEEEEECCCEEEEEECCCCCHHHHH
GAVEAAKWIKGKEPGFYTMFDVLGL
HHHHHHHHHCCCCCCHHHHHHHHCC
>Mature Secondary Structure 
SVRVVVCGALGRMGRRIIELALQDKDVEVVGGVEHPDCVPSIDLGEALGKEELKGKPLT
CEEEEEECHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCHHHHCCHHHHCCCCHH
SRLEELLPYTDVVIEFSGNPTAAVGHAELTTLEKKAIVIGTTGFTKQEIEQIKEFSKNAP
HHHHHHCCCEEEEEEECCCCCEEECCHHHHEECCCEEEEECCCCCHHHHHHHHHHCCCCC
VLLSPNMSLGVNLLFKLAEIAAKVLKDKNFDAEIMEIHHRFKKDAPSGTAMKLAEILSET
EEECCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
LEKKNLVFGRKGEAPRKEDEIGVMALRGGDVVGDHTVYFLGFGERIELTHRATSRDTFAK
HHHHCCEECCCCCCCCCCCCCCEEEEECCCEECCCEEEEEECCCEEEEEECCCCCHHHHH
GAVEAAKWIKGKEPGFYTMFDVLGL
HHHHHHHHHCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320