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The map label for this gene is lnt

Identifier: 15606184

GI number: 15606184

Start: 564520

End: 565839

Strand: Direct

Name: lnt

Synonym: aq_819

Alternate gene names: 15606184

Gene position: 564520-565839 (Clockwise)

Preceding gene: 15606183

Following gene: 15606187

Centisome position: 36.39

GC content: 38.11

Gene sequence:

>1320_bases
ATGCTTACTGATAGACACAAAGAAGTACTTAAAGGTCTATTAGCGGGTATATTGTTTTACCTTTCCTTCTCAAAGTTAAA
TCTTTACTTTCTCGTATTTCCCGCTTTATTTCTGGGAATAAGAAAGAACTTCTTAAGGCTCTTTTCCTTCGGTTTTAGTG
CCTTTTTCCTTTCCCTACTCTGGATAAGGATACCTTTAATAGATTATGGAAATATTAATCCCTTCATAGCCTATCCCGCT
TTAGTTCTGCTCGTTCTTTTCCTGAGCTTATACCAGTTCGGACTTACGTACCTTTTGTGGAGGGTTTTTAAATTTAGTTT
TTTTGCATTTCCATTTTTGTACACCTTAGTTGAAATCTTGCGCTCCCACCTGCCTTACGGAGGCTTCCCTTGGCTGCTTC
TGGGTGTCAACCTCGTGGACATTCCCGTGCTCAGATACACACTAAACGCTGGAACCGTTTTCCTAGGGAGTTTTGTAGTA
CTCCTGATTTCACTCTTTCCCTTATTCAATAAAAAAGAGAAGATCTTTTCTTTAGCAATTATCACTCCTCTTCTAATTTA
CGGTTTTATAAAGGAAACATCTTACAGAGTTACTCACTACGGATTAAAAATCGCGTTAATACAGCCTTTTGTGCCTCAAG
ATGTTAAACTCAACAGGGAATTATTTGAATTGAAATACGGCGAAATAATTGAACTTGTAAAAAAAGCGGTTGAAAAAAAG
CCCGATTTAGTCGTGCTCCCAGAGTCTGCATTTCCTTTTTACCTCGGCGAACTGGAAGAAAAAGGAAAGGAAATTCTTGA
ACTCTCAAAAAAAGTTCCCATAATTACGGGTTTTATAGAAATAGATGAAGGCTTTAAACCTTACAATACGGTAGTTCTCT
TAAAAGACGGCAGAGTAATAGAAAAGTACAGAAAGATCAAATTAGTTCCCTTCGGAGAGTACACACCCTTTCCCTTCAAG
TTTTTTTCCAAATACGTGCCGTACCTGAGCTTTGAAGATTACAACAGGGGAAATAAGGTAAAGTGTTTCCAGTTAAATGG
GTTCTCAATAGGAACACCTGTATGTTTTGAGGTTGCTTATCCTTTCTTCGTTAAGTCTTTCGGGTGTGAATTTATAGCAG
TTTTGACAAACGATGCCTGGTTCAGGGATTCAGAGGGGACTTTTCAGCATATGAAACTCGCAAGAGTAAGAGCAATTGAA
AATGAAAAATTCTTCCTGTGGGTAAACAACACAGGCCCATCGGGTATTATCTCTCCGAGAGGTGAGGTAATAAAGAGTAT
TGATTACGGAAGTAGAGGTATTTTACTTTTCTCCTTTTAA

Upstream 100 bases:

>100_bases
CGGGACTGCTCGGTCAGAACGAAGTTGGTGTTTTCGTCCTTCTCTGGCGCTTAATAAGTCAGTACTTCAGCGCCTTCCTT
GGAGGTATCCTATTTTTCAT

Downstream 100 bases:

>100_bases
TATTTCTTTGACACGCTCGTATATGTAAAACCTCACCTTGACCTCATCTGGAGTATCTAGGAAGAGTTCGTAACCGCAAA
GGATATCACCGTTTTCAAAC

Product: apolipoprotein N-acyltransferase

Products: NA

Alternate protein names: ALP N-acyltransferase

Number of amino acids: Translated: 439; Mature: 439

Protein sequence:

>439_residues
MLTDRHKEVLKGLLAGILFYLSFSKLNLYFLVFPALFLGIRKNFLRLFSFGFSAFFLSLLWIRIPLIDYGNINPFIAYPA
LVLLVLFLSLYQFGLTYLLWRVFKFSFFAFPFLYTLVEILRSHLPYGGFPWLLLGVNLVDIPVLRYTLNAGTVFLGSFVV
LLISLFPLFNKKEKIFSLAIITPLLIYGFIKETSYRVTHYGLKIALIQPFVPQDVKLNRELFELKYGEIIELVKKAVEKK
PDLVVLPESAFPFYLGELEEKGKEILELSKKVPIITGFIEIDEGFKPYNTVVLLKDGRVIEKYRKIKLVPFGEYTPFPFK
FFSKYVPYLSFEDYNRGNKVKCFQLNGFSIGTPVCFEVAYPFFVKSFGCEFIAVLTNDAWFRDSEGTFQHMKLARVRAIE
NEKFFLWVNNTGPSGIISPRGEVIKSIDYGSRGILLFSF

Sequences:

>Translated_439_residues
MLTDRHKEVLKGLLAGILFYLSFSKLNLYFLVFPALFLGIRKNFLRLFSFGFSAFFLSLLWIRIPLIDYGNINPFIAYPA
LVLLVLFLSLYQFGLTYLLWRVFKFSFFAFPFLYTLVEILRSHLPYGGFPWLLLGVNLVDIPVLRYTLNAGTVFLGSFVV
LLISLFPLFNKKEKIFSLAIITPLLIYGFIKETSYRVTHYGLKIALIQPFVPQDVKLNRELFELKYGEIIELVKKAVEKK
PDLVVLPESAFPFYLGELEEKGKEILELSKKVPIITGFIEIDEGFKPYNTVVLLKDGRVIEKYRKIKLVPFGEYTPFPFK
FFSKYVPYLSFEDYNRGNKVKCFQLNGFSIGTPVCFEVAYPFFVKSFGCEFIAVLTNDAWFRDSEGTFQHMKLARVRAIE
NEKFFLWVNNTGPSGIISPRGEVIKSIDYGSRGILLFSF
>Mature_439_residues
MLTDRHKEVLKGLLAGILFYLSFSKLNLYFLVFPALFLGIRKNFLRLFSFGFSAFFLSLLWIRIPLIDYGNINPFIAYPA
LVLLVLFLSLYQFGLTYLLWRVFKFSFFAFPFLYTLVEILRSHLPYGGFPWLLLGVNLVDIPVLRYTLNAGTVFLGSFVV
LLISLFPLFNKKEKIFSLAIITPLLIYGFIKETSYRVTHYGLKIALIQPFVPQDVKLNRELFELKYGEIIELVKKAVEKK
PDLVVLPESAFPFYLGELEEKGKEILELSKKVPIITGFIEIDEGFKPYNTVVLLKDGRVIEKYRKIKLVPFGEYTPFPFK
FFSKYVPYLSFEDYNRGNKVKCFQLNGFSIGTPVCFEVAYPFFVKSFGCEFIAVLTNDAWFRDSEGTFQHMKLARVRAIE
NEKFFLWVNNTGPSGIISPRGEVIKSIDYGSRGILLFSF

Specific function: Transfers the fatty acyl group on membrane lipoproteins

COG id: COG0815

COG function: function code M; Apolipoprotein N-acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain

Homologues:

Organism=Escherichia coli, GI1786878, Length=422, Percent_Identity=24.6445497630332, Blast_Score=112, Evalue=5e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LNT_AQUAE (O67000)

Other databases:

- EMBL:   AE000657
- PIR:   E70371
- RefSeq:   NP_213561.1
- ProteinModelPortal:   O67000
- GeneID:   1193450
- GenomeReviews:   AE000657_GR
- KEGG:   aae:aq_819
- NMPDR:   fig|224324.1.peg.576
- OMA:   IAPYICY
- PhylomeDB:   O67000
- ProtClustDB:   CLSK2748366
- BioCyc:   AAEO224324:AQ_819-MONOMER
- HAMAP:   MF_01148
- InterPro:   IPR004563
- InterPro:   IPR003010
- Gene3D:   G3DSA:3.60.110.10
- TIGRFAMs:   TIGR00546

Pfam domain/function: PF00795 CN_hydrolase; SSF56317 Ntlse/CNhydtse

EC number: 2.3.1.- [C]

Molecular weight: Translated: 50758; Mature: 50758

Theoretical pI: Translated: 9.73; Mature: 9.73

Prosite motif: PS50263 CN_HYDROLASE

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xc38c0dc)-; HASH(0xd16af0c)-; HASH(0xd16e408)-; HASH(0xb61b700)-; HASH(0xc62262c)-;

Cys/Met content:

0.7 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTDRHKEVLKGLLAGILFYLSFSKLNLYFLVFPALFLGIRKNFLRLFSFGFSAFFLSLL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WIRIPLIDYGNINPFIAYPALVLLVLFLSLYQFGLTYLLWRVFKFSFFAFPFLYTLVEIL
HHHHCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RSHLPYGGFPWLLLGVNLVDIPVLRYTLNAGTVFLGSFVVLLISLFPLFNKKEKIFSLAI
HHHCCCCCCCHHHHCCCHHHEEEEEEEECCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
ITPLLIYGFIKETSYRVTHYGLKIALIQPFVPQDVKLNRELFELKYGEIIELVKKAVEKK
HHHHHHHHHHHHCCEEEEEECEEEEEECCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHCC
PDLVVLPESAFPFYLGELEEKGKEILELSKKVPIITGFIEIDEGFKPYNTVVLLKDGRVI
CCEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCEEEEEECCHHH
EKYRKIKLVPFGEYTPFPFKFFSKYVPYLSFEDYNRGNKVKCFQLNGFSIGTPVCFEVAY
HHHHCEEEEECCCCCCCCHHHHHHHCCCEEECCCCCCCEEEEEEECCCCCCCCHHHHHHH
PFFVKSFGCEFIAVLTNDAWFRDSEGTFQHMKLARVRAIENEKFFLWVNNTGPSGIISPR
HHHHHHCCCCEEEEEECCCEEECCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCC
GEVIKSIDYGSRGILLFSF
HHHHHHCCCCCCCEEEEEH
>Mature Secondary Structure
MLTDRHKEVLKGLLAGILFYLSFSKLNLYFLVFPALFLGIRKNFLRLFSFGFSAFFLSLL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WIRIPLIDYGNINPFIAYPALVLLVLFLSLYQFGLTYLLWRVFKFSFFAFPFLYTLVEIL
HHHHCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RSHLPYGGFPWLLLGVNLVDIPVLRYTLNAGTVFLGSFVVLLISLFPLFNKKEKIFSLAI
HHHCCCCCCCHHHHCCCHHHEEEEEEEECCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
ITPLLIYGFIKETSYRVTHYGLKIALIQPFVPQDVKLNRELFELKYGEIIELVKKAVEKK
HHHHHHHHHHHHCCEEEEEECEEEEEECCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHCC
PDLVVLPESAFPFYLGELEEKGKEILELSKKVPIITGFIEIDEGFKPYNTVVLLKDGRVI
CCEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCEEEEEECCHHH
EKYRKIKLVPFGEYTPFPFKFFSKYVPYLSFEDYNRGNKVKCFQLNGFSIGTPVCFEVAY
HHHHCEEEEECCCCCCCCHHHHHHHCCCEEECCCCCCCEEEEEEECCCCCCCCHHHHHHH
PFFVKSFGCEFIAVLTNDAWFRDSEGTFQHMKLARVRAIENEKFFLWVNNTGPSGIISPR
HHHHHHCCCCEEEEEECCCEEECCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCC
GEVIKSIDYGSRGILLFSF
HHHHHHCCCCCCCEEEEEH

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9537320