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The map label for this gene is nuoG [H]

Identifier: 15605931

GI number: 15605931

Start: 297105

End: 299003

Strand: Direct

Name: nuoG [H]

Synonym: aq_437

Alternate gene names: 15605931

Gene position: 297105-299003 (Clockwise)

Preceding gene: 15605926

Following gene: 15605934

Centisome position: 19.15

GC content: 45.87

Gene sequence:

>1899_bases
ATGTCCGAAAAGGTGAAGATTTACATCGACGACGTTGAAATAGAGGCGGAAAAAGGAAAAACTGTCTTACAGGTAGCCCT
CGAAAACGGGATAGACATACCCTACTTCTGTTACCACCCGAGACTCTCCATAGCCGGCGCGTGCAGGATGTGCGTGGTTT
ACTGGGAAGACATAAACAGACTCGTTATTTCCTGTAACCTCCCCGTTCAGGAGGGAATGAGAGTAAGGACGCACAGAACG
AGCGAAATGGTGAGAGAACAACAAAAGTACCTCCTTCAGGCTTTAATGACTAGACACCCCCTTGACTGTCCGATATGCGA
TAAAGCGGGAGAGTGTGACCTCCAGAACCTCGGAGCCATTTACGGACCTCAGAAACAGATAGTCCCCATATCCGCACTTG
AAAAGGAGAGGGAAGAACACGACTGGGAGAGCGATTTTCTGGAGTACTACTCAAACAGGTGTGTTGTTTGTTACAGATGC
ACGAGGGCGTGCGACGAGGTCGTAGGTACGAGAGCCCTTTACGTTGAAGACAGAGGATTTCACTCAAACATAGTTCCCGC
CGTAAGACCTATGGACACATCTACGTGTGAAATGTGCGGTATATGCGTGCACGTTTGCCCCGTAGGCGCTATTATTTCAA
AACCCTTCAAGTATTGGTCCCGTAGCTGGCTTCTGGAAAAGGGAAGAACCGTATGCAACCTCTGTCCCGTGGGATGTGAG
ATACAGATAGAGTACGGAGTGGGAGACTGGCGTTCAAAGAGAAAGGTTTACAGAACGAAACCCACGGACGAGCTAAATAT
CTGCGCCAAGGGCTTTTTTGGCTATGATTCCATAAATCACAAAAGACTTTTAAAAACTAAAGTGGGAAAAAGGGAAGAAA
CTCCCGGTAACGTCGTAAACCTCCTCACAACTATCCTCACCGAACACGGAGGGAAAACTGGAATAGTCTTTTCCGCATAC
CTACCCAAAGAAGTAATAGACGAAGTTTTAAGGATAGCAAAGGCCTCTCAGGCTTACGTCACGGCTCCCCAGAGTGTGGA
TTTATTCAAGTTTTTAGATGAGCTGGAAGAGTATGACTTTCCGACTGTAAAAGAATTTGAAAAGGCGGACGCTTTCGTGT
TCATAGGCGACGACATAACTTCCGTGGCTACCGTTCTTTCTTACTACACAAAGAAGAAGGTTTACAAGATAGGAAAGAGC
GTAAGGGACGAAAAACTCCAGCCCGAAGAGATTACCTACGAAGATCTCCAGAACCTCGAAGGAAACGTGTTCGTCCTAGT
GACACCCCACGCCTTAAACGGTGAAATCAAGGAAGTTGCAACGAAACTAAAAGAGCTTAAAAGGGAAAAAGGCTTTAAGG
TAATCCCCGTGCCAAAAGACGCAAACGCACTCTACCTCTACGAAGTATTGAAAGGTATATACTCCGACCTTCCCGCGGTA
ATGGAAGCCTGCGAAAGGGGAGATATAGAAAACCTCATAATTTTCGGAGAGGACATACTGGAGTTTTACGAAGATAAGGT
ATTCGAAGAATTAAAGGAAAAGCTCGAACACCTCGTGGTTGTGAGCCCCTACGAAGACGGACTGAGCGAATACGCCCATA
TAAAGATACCCATGTCCTTAATGGGAGAAAATGAAGGAACTTATAAAACCTTCTTCGGTGAAGTTAAAGGAAAGAAGTTC
CTTCCTTGGGCTTTCGACGACCTCGCCTTCTGGAAGTACCTCGGTGAAAACTTCAAGGAAGAAAAAGGGCTAAAGGTTGT
AAAAAGCTCATCGAACCTCAGGAGAAGGTTCGAACCGCATCTCTACAGGAACAACTGGATTACACAAAGGAGCCAGAACC
TTTCAAGACTCTATGAAAAGAACAAAGATATAACGGTTTACTACGAAAGGAGTGTTTAG

Upstream 100 bases:

>100_bases
TCGAACCGGCGACCTCCTGCTTGGGAAGCAGGTGCTCTACCTCTGAGCTACGCCCGCTTTTTATTATTAAATTTTATAAT
GGTGTTTTAAGGAGGTTGAT

Downstream 100 bases:

>100_bases
TCTTTCCTCTTTCCGTACTTCTTCTTTACCGCTTTGAATTGAATTTTCCAGTAAAGGAAGAGAACTATCCAAGGGAAGAC
AAGGATGAAAACCAGACTTA

Product: NADH dehydrogenase I chain G

Products: NA

Alternate protein names: NADH dehydrogenase I subunit G 2; NDH-1 subunit G 2 [H]

Number of amino acids: Translated: 632; Mature: 631

Protein sequence:

>632_residues
MSEKVKIYIDDVEIEAEKGKTVLQVALENGIDIPYFCYHPRLSIAGACRMCVVYWEDINRLVISCNLPVQEGMRVRTHRT
SEMVREQQKYLLQALMTRHPLDCPICDKAGECDLQNLGAIYGPQKQIVPISALEKEREEHDWESDFLEYYSNRCVVCYRC
TRACDEVVGTRALYVEDRGFHSNIVPAVRPMDTSTCEMCGICVHVCPVGAIISKPFKYWSRSWLLEKGRTVCNLCPVGCE
IQIEYGVGDWRSKRKVYRTKPTDELNICAKGFFGYDSINHKRLLKTKVGKREETPGNVVNLLTTILTEHGGKTGIVFSAY
LPKEVIDEVLRIAKASQAYVTAPQSVDLFKFLDELEEYDFPTVKEFEKADAFVFIGDDITSVATVLSYYTKKKVYKIGKS
VRDEKLQPEEITYEDLQNLEGNVFVLVTPHALNGEIKEVATKLKELKREKGFKVIPVPKDANALYLYEVLKGIYSDLPAV
MEACERGDIENLIIFGEDILEFYEDKVFEELKEKLEHLVVVSPYEDGLSEYAHIKIPMSLMGENEGTYKTFFGEVKGKKF
LPWAFDDLAFWKYLGENFKEEKGLKVVKSSSNLRRRFEPHLYRNNWITQRSQNLSRLYEKNKDITVYYERSV

Sequences:

>Translated_632_residues
MSEKVKIYIDDVEIEAEKGKTVLQVALENGIDIPYFCYHPRLSIAGACRMCVVYWEDINRLVISCNLPVQEGMRVRTHRT
SEMVREQQKYLLQALMTRHPLDCPICDKAGECDLQNLGAIYGPQKQIVPISALEKEREEHDWESDFLEYYSNRCVVCYRC
TRACDEVVGTRALYVEDRGFHSNIVPAVRPMDTSTCEMCGICVHVCPVGAIISKPFKYWSRSWLLEKGRTVCNLCPVGCE
IQIEYGVGDWRSKRKVYRTKPTDELNICAKGFFGYDSINHKRLLKTKVGKREETPGNVVNLLTTILTEHGGKTGIVFSAY
LPKEVIDEVLRIAKASQAYVTAPQSVDLFKFLDELEEYDFPTVKEFEKADAFVFIGDDITSVATVLSYYTKKKVYKIGKS
VRDEKLQPEEITYEDLQNLEGNVFVLVTPHALNGEIKEVATKLKELKREKGFKVIPVPKDANALYLYEVLKGIYSDLPAV
MEACERGDIENLIIFGEDILEFYEDKVFEELKEKLEHLVVVSPYEDGLSEYAHIKIPMSLMGENEGTYKTFFGEVKGKKF
LPWAFDDLAFWKYLGENFKEEKGLKVVKSSSNLRRRFEPHLYRNNWITQRSQNLSRLYEKNKDITVYYERSV
>Mature_631_residues
SEKVKIYIDDVEIEAEKGKTVLQVALENGIDIPYFCYHPRLSIAGACRMCVVYWEDINRLVISCNLPVQEGMRVRTHRTS
EMVREQQKYLLQALMTRHPLDCPICDKAGECDLQNLGAIYGPQKQIVPISALEKEREEHDWESDFLEYYSNRCVVCYRCT
RACDEVVGTRALYVEDRGFHSNIVPAVRPMDTSTCEMCGICVHVCPVGAIISKPFKYWSRSWLLEKGRTVCNLCPVGCEI
QIEYGVGDWRSKRKVYRTKPTDELNICAKGFFGYDSINHKRLLKTKVGKREETPGNVVNLLTTILTEHGGKTGIVFSAYL
PKEVIDEVLRIAKASQAYVTAPQSVDLFKFLDELEEYDFPTVKEFEKADAFVFIGDDITSVATVLSYYTKKKVYKIGKSV
RDEKLQPEEITYEDLQNLEGNVFVLVTPHALNGEIKEVATKLKELKREKGFKVIPVPKDANALYLYEVLKGIYSDLPAVM
EACERGDIENLIIFGEDILEFYEDKVFEELKEKLEHLVVVSPYEDGLSEYAHIKIPMSLMGENEGTYKTFFGEVKGKKFL
PWAFDDLAFWKYLGENFKEEKGLKVVKSSSNLRRRFEPHLYRNNWITQRSQNLSRLYEKNKDITVYYERSV

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1034

COG function: function code C; NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Homo sapiens, GI33519475, Length=293, Percent_Identity=33.1058020477816, Blast_Score=168, Evalue=1e-41,
Organism=Escherichia coli, GI145693161, Length=409, Percent_Identity=27.8728606356968, Blast_Score=150, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI32566231, Length=288, Percent_Identity=34.0277777777778, Blast_Score=168, Evalue=8e-42,
Organism=Caenorhabditis elegans, GI17565758, Length=288, Percent_Identity=34.0277777777778, Blast_Score=168, Evalue=9e-42,
Organism=Caenorhabditis elegans, GI193209088, Length=248, Percent_Identity=35.0806451612903, Blast_Score=163, Evalue=3e-40,
Organism=Drosophila melanogaster, GI24640559, Length=292, Percent_Identity=32.5342465753425, Blast_Score=173, Evalue=4e-43,
Organism=Drosophila melanogaster, GI24640557, Length=292, Percent_Identity=32.5342465753425, Blast_Score=173, Evalue=4e-43,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR009010
- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR006963
- InterPro:   IPR006655
- InterPro:   IPR000283
- InterPro:   IPR019574 [H]

Pfam domain/function: PF04879 Molybdop_Fe4S4; PF00384 Molybdopterin; PF01568 Molydop_binding; PF10588 NADH-G_4Fe-4S_3 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 72777; Mature: 72646

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: PS00641 COMPLEX1_75K_1 ; PS51085 2FE2S_FER_2 ; PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEKVKIYIDDVEIEAEKGKTVLQVALENGIDIPYFCYHPRLSIAGACRMCVVYWEDINR
CCCCEEEEEEEEEEECCCCCEEEEEEHHCCCCCCEEEECCCCCHHHHHHHHHHHHHCCCE
LVISCNLPVQEGMRVRTHRTSEMVREQQKYLLQALMTRHPLDCPICDKAGECDLQNLGAI
EEEEECCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHCCCC
YGPQKQIVPISALEKEREEHDWESDFLEYYSNRCVVCYRCTRACDEVVGTRALYVEDRGF
CCCCCCEEEHHHHHHHHHHCCHHHHHHHHHCCCEEEEEHHHHHHHHHHCCEEEEEECCCC
HSNIVPAVRPMDTSTCEMCGICVHVCPVGAIISKPFKYWSRSWLLEKGRTVCNLCPVGCE
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCE
IQIEYGVGDWRSKRKVYRTKPTDELNICAKGFFGYDSINHKRLLKTKVGKREETPGNVVN
EEEEECCCCHHHCCCEECCCCCCCHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCHHHHH
LLTTILTEHGGKTGIVFSAYLPKEVIDEVLRIAKASQAYVTAPQSVDLFKFLDELEEYDF
HHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHCCC
PTVKEFEKADAFVFIGDDITSVATVLSYYTKKKVYKIGKSVRDEKLQPEEITYEDLQNLE
CCHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCC
GNVFVLVTPHALNGEIKEVATKLKELKREKGFKVIPVPKDANALYLYEVLKGIYSDLPAV
CCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCEEEECCCCCCEEHHHHHHHHHHHHHHHH
MEACERGDIENLIIFGEDILEFYEDKVFEELKEKLEHLVVVSPYEDGLSEYAHIKIPMSL
HHHHHCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHCCCEEEEEEHHH
MGENEGTYKTFFGEVKGKKFLPWAFDDLAFWKYLGENFKEEKGLKVVKSSSNLRRRFEPH
HCCCCCCHHHHHHHCCCCEECCCHHHHHHHHHHHCCCCCHHCCCEEEECCHHHHHHCCCC
LYRNNWITQRSQNLSRLYEKNKDITVYYERSV
CCCCCCHHHHHHHHHHHHHCCCCEEEEEECCC
>Mature Secondary Structure 
SEKVKIYIDDVEIEAEKGKTVLQVALENGIDIPYFCYHPRLSIAGACRMCVVYWEDINR
CCCEEEEEEEEEEECCCCCEEEEEEHHCCCCCCEEEECCCCCHHHHHHHHHHHHHCCCE
LVISCNLPVQEGMRVRTHRTSEMVREQQKYLLQALMTRHPLDCPICDKAGECDLQNLGAI
EEEEECCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHCCCC
YGPQKQIVPISALEKEREEHDWESDFLEYYSNRCVVCYRCTRACDEVVGTRALYVEDRGF
CCCCCCEEEHHHHHHHHHHCCHHHHHHHHHCCCEEEEEHHHHHHHHHHCCEEEEEECCCC
HSNIVPAVRPMDTSTCEMCGICVHVCPVGAIISKPFKYWSRSWLLEKGRTVCNLCPVGCE
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCE
IQIEYGVGDWRSKRKVYRTKPTDELNICAKGFFGYDSINHKRLLKTKVGKREETPGNVVN
EEEEECCCCHHHCCCEECCCCCCCHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCHHHHH
LLTTILTEHGGKTGIVFSAYLPKEVIDEVLRIAKASQAYVTAPQSVDLFKFLDELEEYDF
HHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHCCC
PTVKEFEKADAFVFIGDDITSVATVLSYYTKKKVYKIGKSVRDEKLQPEEITYEDLQNLE
CCHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCC
GNVFVLVTPHALNGEIKEVATKLKELKREKGFKVIPVPKDANALYLYEVLKGIYSDLPAV
CCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCEEEECCCCCCEEHHHHHHHHHHHHHHHH
MEACERGDIENLIIFGEDILEFYEDKVFEELKEKLEHLVVVSPYEDGLSEYAHIKIPMSL
HHHHHCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHCCCEEEEEEHHH
MGENEGTYKTFFGEVKGKKFLPWAFDDLAFWKYLGENFKEEKGLKVVKSSSNLRRRFEPH
HCCCCCCHHHHHHHCCCCEECCCHHHHHHHHHHHCCCCCHHCCCEEEECCHHHHHHCCCC
LYRNNWITQRSQNLSRLYEKNKDITVYYERSV
CCCCCCHHHHHHHHHHHHHCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11481432 [H]