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The map label for this gene is gltA [H]

Identifier: 15605724

GI number: 15605724

Start: 91085

End: 91864

Strand: Direct

Name: gltA [H]

Synonym: aq_150

Alternate gene names: 15605724

Gene position: 91085-91864 (Clockwise)

Preceding gene: 15605723

Following gene: 15605725

Centisome position: 5.87

GC content: 47.69

Gene sequence:

>780_bases
ATGGCGGACAAGAAGTGGAAAACGGCAATATCTACCCACGTAAATCACGAGCCCTATGTAAGGGGATACAGACTCCTTGA
CCTTGTAGGAAACCTCACCTTCTCGGAAGCAATATATCTCCTCCTCAAGGGAGAACTCCCCTCGGAAGCAGAAGCTAAAA
TGATGGACGCCATTTTTGTCTCCGTAATTGAACACAGCATAGCACCCCCTTCCGTAATAGCCACGCGTGCGGTTATAAGC
GGTGGAAACTCTCTGAACGTGGGAGTCGGTGCTGGAGTTCTGGCTTTCGGTAGTGCCCACGGTGGAGCCCTTGAAGACGC
AATGAAGTTCATGCAGGAAGGAGTAAAGAGCAACAGACCTGTTGAAGAAATAGTAAAGGAGTACTTATCCCAGAAAAAGC
CAATACCCGGTTACGGACACAGGTACTACAAGGAGTTTGACCCAAGAACGAAGAGATTATTTGAACTTGCGGAAAAGTAC
GGTTTTTGCAAGGAACACTGCGAATTTGCAAAGAAAGTAGAAGAAGAGATATACAAACAGAAAGGAAAGAGAATAGTCCT
GAACGTTGACGGTGCCATAGCAGCTATAACTTCCGATATGGGCTTCGACTGGAGGCTCGGTAAAGGATTTTTCATAATCG
GAAGAGTGCCCGGACTCGTGGCCCACGCTTACGAAGAATTAACGCAGGAGAAACCCTTCTCCAAGAGACTTTCCGAAGAG
GAGTATGAATACACCGGAGTTGAACCGAGGGAACTCCCGCCCGAAAGGAAGAAGGTATGA

Upstream 100 bases:

>100_bases
GCAATATCTATGATAGAGGCGGGGGCGGACAGGATAGGCACGAGCAGCGGTATAAGCATAGCCGAAGAATTTTTAAAACG
ACATTTGATATAATGTCCCT

Downstream 100 bases:

>100_bases
AAAGGCTTCTCCCCGTCTTCCTCGCCCTTATACTCTTCGGTTTGTTAGTTTACATAGGACTAAATCAGGATAAACACGAT
CACTACACAATCACAACCCA

Product: citrate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 259; Mature: 258

Protein sequence:

>259_residues
MADKKWKTAISTHVNHEPYVRGYRLLDLVGNLTFSEAIYLLLKGELPSEAEAKMMDAIFVSVIEHSIAPPSVIATRAVIS
GGNSLNVGVGAGVLAFGSAHGGALEDAMKFMQEGVKSNRPVEEIVKEYLSQKKPIPGYGHRYYKEFDPRTKRLFELAEKY
GFCKEHCEFAKKVEEEIYKQKGKRIVLNVDGAIAAITSDMGFDWRLGKGFFIIGRVPGLVAHAYEELTQEKPFSKRLSEE
EYEYTGVEPRELPPERKKV

Sequences:

>Translated_259_residues
MADKKWKTAISTHVNHEPYVRGYRLLDLVGNLTFSEAIYLLLKGELPSEAEAKMMDAIFVSVIEHSIAPPSVIATRAVIS
GGNSLNVGVGAGVLAFGSAHGGALEDAMKFMQEGVKSNRPVEEIVKEYLSQKKPIPGYGHRYYKEFDPRTKRLFELAEKY
GFCKEHCEFAKKVEEEIYKQKGKRIVLNVDGAIAAITSDMGFDWRLGKGFFIIGRVPGLVAHAYEELTQEKPFSKRLSEE
EYEYTGVEPRELPPERKKV
>Mature_258_residues
ADKKWKTAISTHVNHEPYVRGYRLLDLVGNLTFSEAIYLLLKGELPSEAEAKMMDAIFVSVIEHSIAPPSVIATRAVISG
GNSLNVGVGAGVLAFGSAHGGALEDAMKFMQEGVKSNRPVEEIVKEYLSQKKPIPGYGHRYYKEFDPRTKRLFELAEKYG
FCKEHCEFAKKVEEEIYKQKGKRIVLNVDGAIAAITSDMGFDWRLGKGFFIIGRVPGLVAHAYEELTQEKPFSKRLSEEE
YEYTGVEPRELPPERKKV

Specific function: Catalyzes The Synthesis Of 2-Methylcitrate From Propionyl-CoA And Oxaloacetate. Also Catalyzes The Condensation Of Oxaloacetate With Acetyl-CoA But With A Lower Specificity. [C]

COG id: COG0372

COG function: function code C; Citrate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the citrate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1786527, Length=218, Percent_Identity=24.7706422018349, Blast_Score=61, Evalue=6e-11,
Organism=Escherichia coli, GI1786939, Length=216, Percent_Identity=25.9259259259259, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011278
- InterPro:   IPR016142
- InterPro:   IPR016143
- InterPro:   IPR002020
- InterPro:   IPR016141
- InterPro:   IPR019810 [H]

Pfam domain/function: PF00285 Citrate_synt [H]

EC number: =2.3.3.1 [H]

Molecular weight: Translated: 29076; Mature: 28945

Theoretical pI: Translated: 7.69; Mature: 7.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADKKWKTAISTHVNHEPYVRGYRLLDLVGNLTFSEAIYLLLKGELPSEAEAKMMDAIFV
CCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHH
SVIEHSIAPPSVIATRAVISGGNSLNVGVGAGVLAFGSAHGGALEDAMKFMQEGVKSNRP
HHHHHCCCCCHHHHHHHHHCCCCEEECCCCCHHHHHCCCCCCHHHHHHHHHHHHHCCCCC
VEEIVKEYLSQKKPIPGYGHRYYKEFDPRTKRLFELAEKYGFCKEHCEFAKKVEEEIYKQ
HHHHHHHHHHCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
KGKRIVLNVDGAIAAITSDMGFDWRLGKGFFIIGRVPGLVAHAYEELTQEKPFSKRLSEE
CCCEEEEEECCHHHHHHHCCCCCEEECCCEEEEECCHHHHHHHHHHHHHCCCHHHHHCHH
EYEYTGVEPRELPPERKKV
HHHCCCCCCCCCCCHHCCC
>Mature Secondary Structure 
ADKKWKTAISTHVNHEPYVRGYRLLDLVGNLTFSEAIYLLLKGELPSEAEAKMMDAIFV
CCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHH
SVIEHSIAPPSVIATRAVISGGNSLNVGVGAGVLAFGSAHGGALEDAMKFMQEGVKSNRP
HHHHHCCCCCHHHHHHHHHCCCCEEECCCCCHHHHHCCCCCCHHHHHHHHHHHHHCCCCC
VEEIVKEYLSQKKPIPGYGHRYYKEFDPRTKRLFELAEKYGFCKEHCEFAKKVEEEIYKQ
HHHHHHHHHHCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
KGKRIVLNVDGAIAAITSDMGFDWRLGKGFFIIGRVPGLVAHAYEELTQEKPFSKRLSEE
CCCEEEEEECCHHHHHHHCCCCCEEECCCEEEEECCHHHHHHHHHHHHHCCCHHHHHCHH
EYEYTGVEPRELPPERKKV
HHHCCCCCCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9006016; 12397186 [H]