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The map label for this gene is nadD

Identifier: 15605637

GI number: 15605637

Start: 22379

End: 22885

Strand: Direct

Name: nadD

Synonym: aq_036

Alternate gene names: 15605637

Gene position: 22379-22885 (Clockwise)

Preceding gene: 15605635

Following gene: 15605638

Centisome position: 1.44

GC content: 41.62

Gene sequence:

>507_bases
ATGAGAATAGTCTTCGGAGGAAGTTTTGATCCTGTACACGTAGGTCACATAATACTCGCGAGGGACGTCTGTGAACACTT
TAATGCAAAAGAAGTTATATTCGTCCCCACCTATCAGGCACCCCTCAAAGAAAAACACAAAGCAAGCGCTCAGGACAGGT
TAAACATGTTAAAGCTTGCACTTGAAAGGGAAGAGAAGTTCACAATAGAAGACTACGAAATAAGACGAAAGGGAATTTCA
TACACCGTGTACACACTCAAGTACTTAAAGGAGAAGTACGGAGGGGAGGAGCTCTACCTCCTCCTCGGAAGTGACAGTTT
TTTGAAGTTCCATAAATGGAAAGAACCGCGTGAAATACTAAAGCTTGCAAAAATTATTGTGGTCGAGAGGGAAGGGATGT
TGGAAAAGGTGAAGGAATACATAAAGGAGTACTTCCCGGAACTGAGGAAAAATGAAGATATCTTTTTCTACAAAGGCAGA
AGGATAGACATCTCTTCAACCGAATAA

Upstream 100 bases:

>100_bases
GATACGAAAATTATGTAGAGCACGAAAAAAATAACGGAGTAAGAAGTAATTTTTTTCTTTATGCTCATATACCTTATAAA
GTATATATACTACATTCCCT

Downstream 100 bases:

>100_bases
GGAAGAGAGTTTCGGAGGGTAAGAGTATTTACTGCATGGTGCCCGAAAAGGTAGAGGAATACATAAGGGAAAAGAAACTC
TACATTAAATCTCCGGACCT

Product: hypothetical protein

Products: NA

Alternate protein names: Deamido-NAD(+) diphosphorylase; Deamido-NAD(+) pyrophosphorylase; Nicotinate mononucleotide adenylyltransferase; NaMN adenylyltransferase

Number of amino acids: Translated: 168; Mature: 168

Protein sequence:

>168_residues
MRIVFGGSFDPVHVGHIILARDVCEHFNAKEVIFVPTYQAPLKEKHKASAQDRLNMLKLALEREEKFTIEDYEIRRKGIS
YTVYTLKYLKEKYGGEELYLLLGSDSFLKFHKWKEPREILKLAKIIVVEREGMLEKVKEYIKEYFPELRKNEDIFFYKGR
RIDISSTE

Sequences:

>Translated_168_residues
MRIVFGGSFDPVHVGHIILARDVCEHFNAKEVIFVPTYQAPLKEKHKASAQDRLNMLKLALEREEKFTIEDYEIRRKGIS
YTVYTLKYLKEKYGGEELYLLLGSDSFLKFHKWKEPREILKLAKIIVVEREGMLEKVKEYIKEYFPELRKNEDIFFYKGR
RIDISSTE
>Mature_168_residues
MRIVFGGSFDPVHVGHIILARDVCEHFNAKEVIFVPTYQAPLKEKHKASAQDRLNMLKLALEREEKFTIEDYEIRRKGIS
YTVYTLKYLKEKYGGEELYLLLGSDSFLKFHKWKEPREILKLAKIIVVEREGMLEKVKEYIKEYFPELRKNEDIFFYKGR
RIDISSTE

Specific function: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)

COG id: COG1057

COG function: function code H; Nicotinic acid mononucleotide adenylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nadD family

Homologues:

Organism=Escherichia coli, GI1786858, Length=171, Percent_Identity=30.9941520467836, Blast_Score=89, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NADD_AQUAE (O66452)

Other databases:

- EMBL:   AE000657
- PIR:   A70303
- RefSeq:   NP_213012.1
- ProteinModelPortal:   O66452
- SMR:   O66452
- GeneID:   1192649
- GenomeReviews:   AE000657_GR
- KEGG:   aae:aq_036
- NMPDR:   fig|224324.1.peg.27
- HOGENOM:   HBG739448
- OMA:   CDIINGG
- PhylomeDB:   O66452
- BioCyc:   AAEO224324:AQ_036-MONOMER
- BRENDA:   2.7.7.18
- HAMAP:   MF_00244
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR005248
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR12039
- TIGRFAMs:   TIGR00125
- TIGRFAMs:   TIGR00482

Pfam domain/function: PF01467 CTP_transf_2

EC number: =2.7.7.18

Molecular weight: Translated: 19999; Mature: 19999

Theoretical pI: Translated: 9.14; Mature: 9.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIVFGGSFDPVHVGHIILARDVCEHFNAKEVIFVPTYQAPLKEKHKASAQDRLNMLKLA
CEEEECCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHCCHHHHHHHHHHH
LEREEKFTIEDYEIRRKGISYTVYTLKYLKEKYGGEELYLLLGSDSFLKFHKWKEPREIL
HHHCCCCCCCHHHHHHCCCCCHHHHHHHHHHHCCCCEEEEEECCCCHHHHHCCCCHHHHH
KLAKIIVVEREGMLEKVKEYIKEYFPELRKNEDIFFYKGRRIDISSTE
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCEEECCCCC
>Mature Secondary Structure
MRIVFGGSFDPVHVGHIILARDVCEHFNAKEVIFVPTYQAPLKEKHKASAQDRLNMLKLA
CEEEECCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHCCHHHHHHHHHHH
LEREEKFTIEDYEIRRKGISYTVYTLKYLKEKYGGEELYLLLGSDSFLKFHKWKEPREIL
HHHCCCCCCCHHHHHHCCCCCHHHHHHHHHHHCCCCEEEEEECCCCHHHHHCCCCHHHHH
KLAKIIVVEREGMLEKVKEYIKEYFPELRKNEDIFFYKGRRIDISSTE
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320