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The map label for this gene is gptA-2

Identifier: 11499378

GI number: 11499378

Start: 1606761

End: 1607372

Strand: Reverse

Name: gptA-2

Synonym: AF1789

Alternate gene names: NA

Gene position: 1607372-1606761 (Counterclockwise)

Preceding gene: 11499379

Following gene: 11499377

Centisome position: 73.79

GC content: 50.65

Gene sequence:

>612_bases
ATGTACCTCGTTCTGAGCTGGAGATACGTGGAAAGCCTCTGCAGGAAAATTGCGTTTGAGATCGTGGAAGACAAGTTCAT
CCCCGAAAGAATTGTCGCGCTCGCCAAGGGCGGCATTTTCGTTGGAAGTTTGCTAAGCGACTACCTTGGGGTTTCCAGGA
TCGTCTGCCTGGACGTGAAAGACGGCAAAGAAAAGGTCGGGGGTAGCAGGCTGCTGGTGGTTGATGACTTCATCAACACG
GGAAAGACGATGAGCAGGGCTTTAGAGCTTGTTGAGGGTGATGAGGTCAGGACAGCATCCCTTCTGATGCTGGAAAAGTC
AGACTTCATTCCGGACTACCTCGGCGACTACCTTACCGAATACTACTGGGTTATCTTCCCGTGGAACGTTTTTGAGGACA
TTTCTAGCCTCATTTCCGAGATACTGCGTGAAGAAGGGGAGATGAGCCAGTCAAAACTCAGAAGAATCGTTTCCGAGAGG
GGGTTAAACATTCACTCCCTTGAGGCCGTTTTCCCCGGAAAATTTGAGGACGTGCTCGAGTTCATGGAGCTGAAGGGCCT
GATAGAAAAGAGAACTGAGGGAGGTAGGGTTTACTGGAGGCTGAGCGAATGA

Upstream 100 bases:

>100_bases
GAGTTTCAGAAAAAGGTCAATCTCAACCCGATGCCCGGCAACGTTGCGGTTTACAGGCCGGGAGGAGAGGTTATAAGGCT
GAGGTTCTACGGTGAGTAAA

Downstream 100 bases:

>100_bases
TCGGCATAATCGGGGGCACGCACATTCTCGAAATTAAGGTTCTGAAAGATGTTGAGGAGACGAGAATTGAGACTCCCTAC
GGAACAGCGGAAATCGATGT

Product: xanthine-guanine phosphoribosyltransferase (gptA-2)

Products: 5-phospho-alpha-D-ribose 1-diphosphate; xanthine

Alternate protein names: Xanthine-Guanine Phosphoribosyltransferase; Purine Phosphoribosyltransferase; Hypoxanthine/Guanine Phosphoribosyltransferase; Phosphoribosyl Transferase Domain Protein; Phosphoribosyl Transferase; Xanthine-Guanine Phosphoribosyltransferase Conjectural; Phosphoribosyltransferase-Like Protein; Phosphoribosyl Transferase Domain-Containing Protein; Purine Phosphoribosyltransferase Related Protein

Number of amino acids: Translated: 203; Mature: 203

Protein sequence:

>203_residues
MYLVLSWRYVESLCRKIAFEIVEDKFIPERIVALAKGGIFVGSLLSDYLGVSRIVCLDVKDGKEKVGGSRLLVVDDFINT
GKTMSRALELVEGDEVRTASLLMLEKSDFIPDYLGDYLTEYYWVIFPWNVFEDISSLISEILREEGEMSQSKLRRIVSER
GLNIHSLEAVFPGKFEDVLEFMELKGLIEKRTEGGRVYWRLSE

Sequences:

>Translated_203_residues
MYLVLSWRYVESLCRKIAFEIVEDKFIPERIVALAKGGIFVGSLLSDYLGVSRIVCLDVKDGKEKVGGSRLLVVDDFINT
GKTMSRALELVEGDEVRTASLLMLEKSDFIPDYLGDYLTEYYWVIFPWNVFEDISSLISEILREEGEMSQSKLRRIVSER
GLNIHSLEAVFPGKFEDVLEFMELKGLIEKRTEGGRVYWRLSE
>Mature_203_residues
MYLVLSWRYVESLCRKIAFEIVEDKFIPERIVALAKGGIFVGSLLSDYLGVSRIVCLDVKDGKEKVGGSRLLVVDDFINT
GKTMSRALELVEGDEVRTASLLMLEKSDFIPDYLGDYLTEYYWVIFPWNVFEDISSLISEILREEGEMSQSKLRRIVSER
GLNIHSLEAVFPGKFEDVLEFMELKGLIEKRTEGGRVYWRLSE

Specific function: Unknown

COG id: COG2236

COG function: function code R; Predicted phosphoribosyltransferases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.4.2.22

Molecular weight: Translated: 23322; Mature: 23322

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYLVLSWRYVESLCRKIAFEIVEDKFIPERIVALAKGGIFVGSLLSDYLGVSRIVCLDVK
CEEEEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHCHHEEEEEECC
DGKEKVGGSRLLVVDDFINTGKTMSRALELVEGDEVRTASLLMLEKSDFIPDYLGDYLTE
CCHHHCCCCEEEEEHHHHHCCHHHHHHHHHHCCCCCHHHHHEEEECCCCCHHHHHHHHHH
YYWVIFPWNVFEDISSLISEILREEGEMSQSKLRRIVSERGLNIHSLEAVFPGKFEDVLE
HEEEEECHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEECCCCCCCHHHHHH
FMELKGLIEKRTEGGRVYWRLSE
HHHHHHHHHHCCCCCEEEEEECC
>Mature Secondary Structure
MYLVLSWRYVESLCRKIAFEIVEDKFIPERIVALAKGGIFVGSLLSDYLGVSRIVCLDVK
CEEEEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHCHHEEEEEECC
DGKEKVGGSRLLVVDDFINTGKTMSRALELVEGDEVRTASLLMLEKSDFIPDYLGDYLTE
CCHHHCCCCEEEEEHHHHHCCHHHHHHHHHHCCCCCHHHHHEEEECCCCCHHHHHHHHHH
YYWVIFPWNVFEDISSLISEILREEGEMSQSKLRRIVSERGLNIHSLEAVFPGKFEDVLE
HEEEEECHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEECCCCCCCHHHHHH
FMELKGLIEKRTEGGRVYWRLSE
HHHHHHHHHHCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 9-(5-phospho-beta-D-ribosyl)xanthine; diphosphate

Specific reaction: 9-(5-phospho-beta-D-ribosyl)xanthine + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + xanthine

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA