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The map label for this gene is dppA

Identifier: 11499356

GI number: 11499356

Start: 1585823

End: 1587385

Strand: Reverse

Name: dppA

Synonym: AF1767

Alternate gene names: 11499356

Gene position: 1587385-1585823 (Counterclockwise)

Preceding gene: 11499364

Following gene: 11499354

Centisome position: 72.87

GC content: 51.63

Gene sequence:

>1563_bases
ATGAAGAAACTATACGTTTTGGCGCTTTTGGTTGCTGCAGTGCTGCTACTGGGCTGTGCCCAACAGCCGGAGCAACCGCA
GAAAGAGGAAGCTAAGAAGCTGAAGATTGAGCTCTGGTGGACTCCAACTCACTACGGTGACACTGAGAAAGATTTGGCAC
AGGTTCTGAAGGAGCAGCTTGAGGCAACGGGAATGATTGAGGTTGAGCTGAAGAGCGCCGAGTGGTCAACTTTCCAGGAC
TATTCCAGAAAGGGAGCGATGATGGCTTCGCTGTTCGGATGGTATCCTGACTACCTCGACCCTGATGACTACACCACACC
CTTCCTGAGTTGCACGGCAAACAACTGGCTCGGCTATCCGTACTGCGACCCGGAGATGGATGAACTGCTTGAGAAGGCAT
CAACAGCAACCTCGATGGAGGAGAGAGAGAAGCTTTACAAGCAGATACAGCAGAAGCTTGCTGAGGATGCACCGATAATC
CCGCTCGTACAGGGCAAGCTGACGATAGTTGCAAAGGACGACATCAAGGGAATTACCCTCGACCCGACCATGATTTTCAG
GTACTATCTTGTCTACTCCGAGGAGCAGAAGGACACAATCACCATCGGTGTAACTGACAAGATTACCGATCTCGACCCTG
CCAATGCTTACGACTTCTACACATGGGAAATTATGAACAACGTCATGGGAGGGCTGGTAAGGTACAAGCCCGGCACAACA
GAACTTGAGCCATACCTTGCTGAAAGCTGGGAAGTCAGTGAGGATGGCCTTGTTTACACCTTCCACCTCAGGCAGGATCT
GAAATTTGCTGACGGCACCCCATGCAAGGCGCAGGATGTGGTGAGAAGCATCAAGAGAGTCATGACCATTCAGGGCGACC
CCTCATGGCTCGTTACTCACTTCGTCGAGGATGTGGAGGCTGTTGACGACTACACTGTGAAGTTCACGCTCAAGAAGCCA
GCAGCGTACTTTGTCTCACTGCTTGCAACACCGCCATACTTCCCCGTCCACCCGGCATACAAGGCAGATGAAATAGACCC
CGACCAGACTGCCGGTGGAGTTGGGCCCTACAAGATAGTGGAGTGGAAGAGAGACCAGGAGCTAATTCTCGAAGCCAACC
CGAACTTCTTTGGAGAGCAGCCAATGACAAAGAGAATTGTGGTGAAGTTCTACAAGGACGCCACAACTCTAAGACTTGCC
ATCGAGAAGGGAGAGGTTGACATCGCATGGAGAACGCTCACACCAATCGACATCGAATCCCTGAAGGCAAAGGAGGGTCT
GCAGGTTATCGAGGCTCCGGGTGGTTTCATCAGGTACCTCGTTCTCAACGCCAATGAAAACACAGACTACCCGACAAAGA
ACATCTACGTCAGAAAGGCCATTGCAGCTGCAATTGACAGAGAGGACATCGCCCAGAGGGTTTACAGAGGGACCGTTGAG
CCGCTGTACTCCTTAATACCAATCGGTATGTGGAGCCACGAGGACGTCTTCAAGGATATGTATGGAGATGGCAACATCGA
GCTTGCCAAGGAGTACCTGAAGAAGGCTGGCTATTCCGAATAA

Upstream 100 bases:

>100_bases
TCTTATGCTCCCAGCCGGAGCGATAAAAAGATTAGCCCATTAAATTTTTGCCAGATACACTCAAGATACTGTTATATATC
ATAACACGGACATTTACAAC

Downstream 100 bases:

>100_bases
TTTTTTGATTTATTTTTTATTTGGGCTCAAAATTAAAAGGTAGAAACTCTTTCAGCAAGTTCAGGGCCTCTTAAGTCCCC
TTCTCAGCCGCTCAAGATTC

Product: dipeptide ABC transporter, dipeptide-binding protein (dppA)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 520; Mature: 520

Protein sequence:

>520_residues
MKKLYVLALLVAAVLLLGCAQQPEQPQKEEAKKLKIELWWTPTHYGDTEKDLAQVLKEQLEATGMIEVELKSAEWSTFQD
YSRKGAMMASLFGWYPDYLDPDDYTTPFLSCTANNWLGYPYCDPEMDELLEKASTATSMEEREKLYKQIQQKLAEDAPII
PLVQGKLTIVAKDDIKGITLDPTMIFRYYLVYSEEQKDTITIGVTDKITDLDPANAYDFYTWEIMNNVMGGLVRYKPGTT
ELEPYLAESWEVSEDGLVYTFHLRQDLKFADGTPCKAQDVVRSIKRVMTIQGDPSWLVTHFVEDVEAVDDYTVKFTLKKP
AAYFVSLLATPPYFPVHPAYKADEIDPDQTAGGVGPYKIVEWKRDQELILEANPNFFGEQPMTKRIVVKFYKDATTLRLA
IEKGEVDIAWRTLTPIDIESLKAKEGLQVIEAPGGFIRYLVLNANENTDYPTKNIYVRKAIAAAIDREDIAQRVYRGTVE
PLYSLIPIGMWSHEDVFKDMYGDGNIELAKEYLKKAGYSE

Sequences:

>Translated_520_residues
MKKLYVLALLVAAVLLLGCAQQPEQPQKEEAKKLKIELWWTPTHYGDTEKDLAQVLKEQLEATGMIEVELKSAEWSTFQD
YSRKGAMMASLFGWYPDYLDPDDYTTPFLSCTANNWLGYPYCDPEMDELLEKASTATSMEEREKLYKQIQQKLAEDAPII
PLVQGKLTIVAKDDIKGITLDPTMIFRYYLVYSEEQKDTITIGVTDKITDLDPANAYDFYTWEIMNNVMGGLVRYKPGTT
ELEPYLAESWEVSEDGLVYTFHLRQDLKFADGTPCKAQDVVRSIKRVMTIQGDPSWLVTHFVEDVEAVDDYTVKFTLKKP
AAYFVSLLATPPYFPVHPAYKADEIDPDQTAGGVGPYKIVEWKRDQELILEANPNFFGEQPMTKRIVVKFYKDATTLRLA
IEKGEVDIAWRTLTPIDIESLKAKEGLQVIEAPGGFIRYLVLNANENTDYPTKNIYVRKAIAAAIDREDIAQRVYRGTVE
PLYSLIPIGMWSHEDVFKDMYGDGNIELAKEYLKKAGYSE
>Mature_520_residues
MKKLYVLALLVAAVLLLGCAQQPEQPQKEEAKKLKIELWWTPTHYGDTEKDLAQVLKEQLEATGMIEVELKSAEWSTFQD
YSRKGAMMASLFGWYPDYLDPDDYTTPFLSCTANNWLGYPYCDPEMDELLEKASTATSMEEREKLYKQIQQKLAEDAPII
PLVQGKLTIVAKDDIKGITLDPTMIFRYYLVYSEEQKDTITIGVTDKITDLDPANAYDFYTWEIMNNVMGGLVRYKPGTT
ELEPYLAESWEVSEDGLVYTFHLRQDLKFADGTPCKAQDVVRSIKRVMTIQGDPSWLVTHFVEDVEAVDDYTVKFTLKKP
AAYFVSLLATPPYFPVHPAYKADEIDPDQTAGGVGPYKIVEWKRDQELILEANPNFFGEQPMTKRIVVKFYKDATTLRLA
IEKGEVDIAWRTLTPIDIESLKAKEGLQVIEAPGGFIRYLVLNANENTDYPTKNIYVRKAIAAAIDREDIAQRVYRGTVE
PLYSLIPIGMWSHEDVFKDMYGDGNIELAKEYLKKAGYSE

Specific function: Part of the ABC transporter complex ddpABCDF, which is probably involved in D,D-dipeptide transport [H]

COG id: COG0747

COG function: function code E; ABC-type dipeptide transport system, periplasmic component

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1787762, Length=337, Percent_Identity=31.1572700296736, Blast_Score=158, Evalue=1e-39,
Organism=Escherichia coli, GI1789966, Length=312, Percent_Identity=31.4102564102564, Blast_Score=128, Evalue=8e-31,
Organism=Escherichia coli, GI1787551, Length=346, Percent_Identity=28.9017341040462, Blast_Score=118, Evalue=1e-27,
Organism=Escherichia coli, GI1787052, Length=339, Percent_Identity=26.8436578171091, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1789887, Length=259, Percent_Identity=28.957528957529, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1789397, Length=381, Percent_Identity=25.7217847769029, Blast_Score=91, Evalue=3e-19,
Organism=Escherichia coli, GI1787495, Length=310, Percent_Identity=28.3870967741935, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI87081878, Length=352, Percent_Identity=26.1363636363636, Blast_Score=80, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 59292; Mature: 59292

Theoretical pI: Translated: 4.48; Mature: 4.48

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLYVLALLVAAVLLLGCAQQPEQPQKEEAKKLKIELWWTPTHYGDTEKDLAQVLKEQL
CCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCEEEEEEEECCCCCCCCHHHHHHHHHHHH
EATGMIEVELKSAEWSTFQDYSRKGAMMASLFGWYPDYLDPDDYTTPFLSCTANNWLGYP
HHCCEEEEEEECCCCCHHHHHHHCCHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCC
YCDPEMDELLEKASTATSMEEREKLYKQIQQKLAEDAPIIPLVQGKLTIVAKDDIKGITL
CCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCEEEEECCEEEEEEECCCCCEEE
DPTMIFRYYLVYSEEQKDTITIGVTDKITDLDPANAYDFYTWEIMNNVMGGLVRYKPGTT
CHHHHHHHHEEEECCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHCCEEEECCCCC
ELEPYLAESWEVSEDGLVYTFHLRQDLKFADGTPCKAQDVVRSIKRVMTIQGDPSWLVTH
CCCCHHHCCCCCCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHEEECCCCCHHHHH
FVEDVEAVDDYTVKFTLKKPAAYFVSLLATPPYFPVHPAYKADEIDPDQTAGGVGPYKIV
HHHHHHHCCCEEEEEEECCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEE
EWKRDQELILEANPNFFGEQPMTKRIVVKFYKDATTLRLAIEKGEVDIAWRTLTPIDIES
EECCCCEEEEECCCCCCCCCCCHHHHHHHHHCCCEEEEEEEECCCEEEEEEEECCCCHHH
LKAKEGLQVIEAPGGFIRYLVLNANENTDYPTKNIYVRKAIAAAIDREDIAQRVYRGTVE
HHHHCCCEEEECCCCEEEEEEEECCCCCCCCCCCEEHHHHHHHHHCHHHHHHHHHHCCHH
PLYSLIPIGMWSHEDVFKDMYGDGNIELAKEYLKKAGYSE
HHHHHHCCCCCCHHHHHHHHCCCCCHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKKLYVLALLVAAVLLLGCAQQPEQPQKEEAKKLKIELWWTPTHYGDTEKDLAQVLKEQL
CCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCEEEEEEEECCCCCCCCHHHHHHHHHHHH
EATGMIEVELKSAEWSTFQDYSRKGAMMASLFGWYPDYLDPDDYTTPFLSCTANNWLGYP
HHCCEEEEEEECCCCCHHHHHHHCCHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCC
YCDPEMDELLEKASTATSMEEREKLYKQIQQKLAEDAPIIPLVQGKLTIVAKDDIKGITL
CCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCEEEEECCEEEEEEECCCCCEEE
DPTMIFRYYLVYSEEQKDTITIGVTDKITDLDPANAYDFYTWEIMNNVMGGLVRYKPGTT
CHHHHHHHHEEEECCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHCCEEEECCCCC
ELEPYLAESWEVSEDGLVYTFHLRQDLKFADGTPCKAQDVVRSIKRVMTIQGDPSWLVTH
CCCCHHHCCCCCCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHEEECCCCCHHHHH
FVEDVEAVDDYTVKFTLKKPAAYFVSLLATPPYFPVHPAYKADEIDPDQTAGGVGPYKIV
HHHHHHHCCCEEEEEEECCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEE
EWKRDQELILEANPNFFGEQPMTKRIVVKFYKDATTLRLAIEKGEVDIAWRTLTPIDIES
EECCCCEEEEECCCCCCCCCCCHHHHHHHHHCCCEEEEEEEECCCEEEEEEEECCCCHHH
LKAKEGLQVIEAPGGFIRYLVLNANENTDYPTKNIYVRKAIAAAIDREDIAQRVYRGTVE
HHHHCCCEEEECCCCEEEEEEEECCCCCCCCCCCEEHHHHHHHHHCHHHHHHHHHHCCHH
PLYSLIPIGMWSHEDVFKDMYGDGNIELAKEYLKKAGYSE
HHHHHHCCCCCCHHHHHHHHCCCCCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 9751644 [H]