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The map label for this gene is hypE

Identifier: 11498961

GI number: 11498961

Start: 1218271

End: 1219305

Strand: Reverse

Name: hypE

Synonym: AF1365

Alternate gene names: 11498961

Gene position: 1219305-1218271 (Counterclockwise)

Preceding gene: 11498962

Following gene: 11498951

Centisome position: 55.97

GC content: 52.27

Gene sequence:

>1035_bases
ATGTCGGTAATCAGGAAGGAGGATGGAGCTGGAGGAAAGTACATGGTAGAGCTCCTCAAAAAGCACGTTTTTCCAAAAAT
TGCTTCCAGAGCAGGAGAGATAGCCTTGGAGGATATGGAAGACTCTTCGGACTTTTGCGACGATTTTGCTTTTACAACAG
ACTCCTATGTTGTCTCCCCACCGATTTTCAGGGGCGGGAGCATAGGGAGCCTTTCTGTCTGCGGCACGAGCAATGATCTG
GCTGTGATGGGCGCAAAGCCCGAATTCATGTCTCTCGCACTCGTAATTCAGGATGGCTTCCCTCTCGGCGATTTCAGGAG
GATTATGGATGATATCAGAGATTCTGTGGAGCTTGTGAACTTGAGCATAATAACCGGCGATACGAAGGTTGTGGAGTCGA
ACGTTGGCATAATCGTCAACACTGCCGGGATAGGAAGGAGGAGCGAGGAGCTTGAGAGAAATCTGGAAGTCCTGAGGGAG
CTGAGAGATTACCCCTACAGGTGGGTAAGGGATAAAGGTCTGAAAGAGGGGGATGCGATAATAGTCAGCGGGAGCATTGC
GGAGCACGCTGCGGTTATAATGGCAGAGAGGATGGGCTTTGAGGTTGAGTTCAAGTCAGACGTTTACCCCGTGTGGCTCT
TCGTCAGGGAAGCGCTGAGGAGAGGAGGAGTTACGGCGATGAAGGACCCCACGAGAGGGGGAATTGCTGCAGCGCTCAAC
GAGATGGCAGAGAAGAGCGGAGTGGGGATAAAGATTTTTGAGGAAAGGATTCCGCTGAAGGATGAGGTCAGGGGGCTCTG
CGAGCTTCTCGGCCTCGACCCCCTGACAATGGCCAACGAGGGGAAGGTTGTCTTTGGAGTCCACCCCGAGATGGCTGATG
AAGTGTTAAAGGCTTTACACAAGGCAGGGCAGAAGGAGGCTGAGATAATTGGCTACGCAACCAAGGAATTCGCGGAGGTT
GTTTTAGAGACGGCTGTGGGAACAACGAGAGTTGTACCCCAGCCAATCTCAGACCCCATTCCGAGGGTTTGTTAG

Upstream 100 bases:

>100_bases
AGGGTTTGCGGAGAGATTGTTGTGCCCTCCCTTTATCCTCTTGGTGATAATGGAATAAGTCTTGGGCAGATTTACGCCTT
GAAAGCTCTGGAGGGGTAAA

Downstream 100 bases:

>100_bases
GTCTACGCGAATTGATGCCAAAAAACCCGTAAATTGGTTTGAAGGGTTTCGAAAATTAGTAAGAAATCACCTGTATAGCT
ATAGCCTCCTCGTCTTTCTT

Product: hydrogenase expression/formation protein (hypE)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 344; Mature: 343

Protein sequence:

>344_residues
MSVIRKEDGAGGKYMVELLKKHVFPKIASRAGEIALEDMEDSSDFCDDFAFTTDSYVVSPPIFRGGSIGSLSVCGTSNDL
AVMGAKPEFMSLALVIQDGFPLGDFRRIMDDIRDSVELVNLSIITGDTKVVESNVGIIVNTAGIGRRSEELERNLEVLRE
LRDYPYRWVRDKGLKEGDAIIVSGSIAEHAAVIMAERMGFEVEFKSDVYPVWLFVREALRRGGVTAMKDPTRGGIAAALN
EMAEKSGVGIKIFEERIPLKDEVRGLCELLGLDPLTMANEGKVVFGVHPEMADEVLKALHKAGQKEAEIIGYATKEFAEV
VLETAVGTTRVVPQPISDPIPRVC

Sequences:

>Translated_344_residues
MSVIRKEDGAGGKYMVELLKKHVFPKIASRAGEIALEDMEDSSDFCDDFAFTTDSYVVSPPIFRGGSIGSLSVCGTSNDL
AVMGAKPEFMSLALVIQDGFPLGDFRRIMDDIRDSVELVNLSIITGDTKVVESNVGIIVNTAGIGRRSEELERNLEVLRE
LRDYPYRWVRDKGLKEGDAIIVSGSIAEHAAVIMAERMGFEVEFKSDVYPVWLFVREALRRGGVTAMKDPTRGGIAAALN
EMAEKSGVGIKIFEERIPLKDEVRGLCELLGLDPLTMANEGKVVFGVHPEMADEVLKALHKAGQKEAEIIGYATKEFAEV
VLETAVGTTRVVPQPISDPIPRVC
>Mature_343_residues
SVIRKEDGAGGKYMVELLKKHVFPKIASRAGEIALEDMEDSSDFCDDFAFTTDSYVVSPPIFRGGSIGSLSVCGTSNDLA
VMGAKPEFMSLALVIQDGFPLGDFRRIMDDIRDSVELVNLSIITGDTKVVESNVGIIVNTAGIGRRSEELERNLEVLREL
RDYPYRWVRDKGLKEGDAIIVSGSIAEHAAVIMAERMGFEVEFKSDVYPVWLFVREALRRGGVTAMKDPTRGGIAAALNE
MAEKSGVGIKIFEERIPLKDEVRGLCELLGLDPLTMANEGKVVFGVHPEMADEVLKALHKAGQKEAEIIGYATKEFAEVV
LETAVGTTRVVPQPISDPIPRVC

Specific function: Unknown

COG id: COG0309

COG function: function code O; Hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypE family [H]

Homologues:

Organism=Escherichia coli, GI226510967, Length=354, Percent_Identity=34.180790960452, Blast_Score=201, Evalue=5e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR011854
- InterPro:   IPR016188 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: NA

Molecular weight: Translated: 37611; Mature: 37480

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVIRKEDGAGGKYMVELLKKHVFPKIASRAGEIALEDMEDSSDFCDDFAFTTDSYVVSP
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHCCCCCCEEECC
PIFRGGSIGSLSVCGTSNDLAVMGAKPEFMSLALVIQDGFPLGDFRRIMDDIRDSVELVN
CCCCCCCCCEEEEECCCCCEEEEECCCHHHEEEEEEECCCCHHHHHHHHHHHHHHHEEEE
LSIITGDTKVVESNVGIIVNTAGIGRRSEELERNLEVLRELRDYPYRWVRDKGLKEGDAI
EEEEECCCEEEECCCCEEEECCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCEE
IVSGSIAEHAAVIMAERMGFEVEFKSDVYPVWLFVREALRRGGVTAMKDPTRGGIAAALN
EEECCHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHCCCEEECCCCCCHHHHHHH
EMAEKSGVGIKIFEERIPLKDEVRGLCELLGLDPLTMANEGKVVFGVHPEMADEVLKALH
HHHHHCCCCEEEECCCCCCHHHHHHHHHHHCCCCCEECCCCCEEEEECHHHHHHHHHHHH
KAGQKEAEIIGYATKEFAEVVLETAVGTTRVVPQPISDPIPRVC
HCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SVIRKEDGAGGKYMVELLKKHVFPKIASRAGEIALEDMEDSSDFCDDFAFTTDSYVVSP
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHCCCCCCEEECC
PIFRGGSIGSLSVCGTSNDLAVMGAKPEFMSLALVIQDGFPLGDFRRIMDDIRDSVELVN
CCCCCCCCCEEEEECCCCCEEEEECCCHHHEEEEEEECCCCHHHHHHHHHHHHHHHEEEE
LSIITGDTKVVESNVGIIVNTAGIGRRSEELERNLEVLRELRDYPYRWVRDKGLKEGDAI
EEEEECCCEEEECCCCEEEECCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCEE
IVSGSIAEHAAVIMAERMGFEVEFKSDVYPVWLFVREALRRGGVTAMKDPTRGGIAAALN
EEECCHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHCCCEEECCCCCCHHHHHHH
EMAEKSGVGIKIFEERIPLKDEVRGLCELLGLDPLTMANEGKVVFGVHPEMADEVLKALH
HHHHHCCCCEEEECCCCCCHHHHHHHHHHHCCCCCEECCCCCEEEEECHHHHHHHHHHHH
KAGQKEAEIIGYATKEFAEVVLETAVGTTRVVPQPISDPIPRVC
HCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]