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The map label for this gene is pfpI

Identifier: 11498880

GI number: 11498880

Start: 1142860

End: 1143366

Strand: Reverse

Name: pfpI

Synonym: AF1281

Alternate gene names: 11498880

Gene position: 1143366-1142860 (Counterclockwise)

Preceding gene: 11498884

Following gene: 11498879

Centisome position: 52.49

GC content: 52.27

Gene sequence:

>507_bases
ATGAGGGTGCTGATTCTGGCTGAGAATGAATTTGAGGACCTCGAGCTTTTCTACCCGCTCTACAGGCTCCGGGAAGAGGG
GTTAGAGGTGAAGGTCGCCTCATCGTCTCTCGAAGTCAGGGTGGGGAAGAAAGGCTATCAGGTGAGGCCGGATTTAACCT
ACGAGGATGTGAAGGTTGAGGATTACGCCGGGCTGGTCATCCCTGGCGGAAAGTCCCCTGAAAGGGTCAGAATAAACGAG
AGGGCTGTTGAGATAGTCAAGGACTTTTTGGAGCTTGGAAAGCCAGTTGCAGCCATCTGCCACGGACCTCAGCTTTTGAT
ATCGGCGATGGCCGTTAAGGGAAGAAGAATGACGTCCTGGATTGGAATAAGAGACGATTTGATTGCAGCGGGAGCCCTTT
ACGAAGACAGGCCGGTTGTTGTTGACGGGAACGTAATAACCTCCCGTATGCCCGACGACTTGCCGTACTTCTGCGGGGAG
CTTATCAAAATCCTTAAGCGATACTGA

Upstream 100 bases:

>100_bases
CGCTATTTTTTCTACCTTCTCGGCAAGCTGAAGGTTTCTAAGTTTTCTCTCCACAAGTAAGATTGGGAAAAGGTAAATAT
TAGGTTTTTGAGCTGTTATC

Downstream 100 bases:

>100_bases
TATAAACACCAATGCCCCCCTACCCTTAAGGGCCCGTGGCTCAGCATGGATAGAGCGACGGCCTTCTAAGCCGTAGATCG
CGGGTTCAAATCCCGCCGGG

Product: intracellular protease (pfpI)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 168; Mature: 168

Protein sequence:

>168_residues
MRVLILAENEFEDLELFYPLYRLREEGLEVKVASSSLEVRVGKKGYQVRPDLTYEDVKVEDYAGLVIPGGKSPERVRINE
RAVEIVKDFLELGKPVAAICHGPQLLISAMAVKGRRMTSWIGIRDDLIAAGALYEDRPVVVDGNVITSRMPDDLPYFCGE
LIKILKRY

Sequences:

>Translated_168_residues
MRVLILAENEFEDLELFYPLYRLREEGLEVKVASSSLEVRVGKKGYQVRPDLTYEDVKVEDYAGLVIPGGKSPERVRINE
RAVEIVKDFLELGKPVAAICHGPQLLISAMAVKGRRMTSWIGIRDDLIAAGALYEDRPVVVDGNVITSRMPDDLPYFCGE
LIKILKRY
>Mature_168_residues
MRVLILAENEFEDLELFYPLYRLREEGLEVKVASSSLEVRVGKKGYQVRPDLTYEDVKVEDYAGLVIPGGKSPERVRINE
RAVEIVKDFLELGKPVAAICHGPQLLISAMAVKGRRMTSWIGIRDDLIAAGALYEDRPVVVDGNVITSRMPDDLPYFCGE
LIKILKRY

Specific function: Unknown

COG id: COG0693

COG function: function code R; Putative intracellular protease/amidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PfpI endopeptidase domain

Homologues:

Organism=Escherichia coli, GI87082219, Length=167, Percent_Identity=41.3173652694611, Blast_Score=121, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI17558714, Length=164, Percent_Identity=28.6585365853659, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y1281_ARCFU (O28987)

Other databases:

- EMBL:   AE000782
- PIR:   H69409
- RefSeq:   NP_070109.1
- ProteinModelPortal:   O28987
- MEROPS:   C56.001
- GeneID:   1484506
- GenomeReviews:   AE000782_GR
- KEGG:   afu:AF1281
- NMPDR:   fig|224325.1.peg.1269
- TIGR:   AF_1281
- HOGENOM:   HBG646910
- OMA:   VATICHG
- BioCyc:   AFUL224325:AF_1281-MONOMER
- InterPro:   IPR006286
- InterPro:   IPR002818
- TIGRFAMs:   TIGR01382

Pfam domain/function: PF01965 DJ-1_PfpI

EC number: NA

Molecular weight: Translated: 18968; Mature: 18968

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: PS51276 PEPTIDASE_C56_PFPI

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVLILAENEFEDLELFYPLYRLREEGLEVKVASSSLEVRVGKKGYQVRPDLTYEDVKVE
CEEEEEECCCCCHHHHHHHHHHHHHCCCEEEEECCCEEEEECCCCCEECCCCCCCCEEEE
DYAGLVIPGGKSPERVRINERAVEIVKDFLELGKPVAAICHGPQLLISAMAVKGRRMTSW
CCCCEEECCCCCCCEEEHHHHHHHHHHHHHHHCCCCEEHHCCHHHHHHHHHHCCCCHHEE
IGIRDDLIAAGALYEDRPVVVDGNVITSRMPDDLPYFCGELIKILKRY
ECCCHHHHHHCCEECCCCEEEECCEEECCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MRVLILAENEFEDLELFYPLYRLREEGLEVKVASSSLEVRVGKKGYQVRPDLTYEDVKVE
CEEEEEECCCCCHHHHHHHHHHHHHCCCEEEEECCCEEEEECCCCCEECCCCCCCCEEEE
DYAGLVIPGGKSPERVRINERAVEIVKDFLELGKPVAAICHGPQLLISAMAVKGRRMTSW
CCCCEEECCCCCCCEEEHHHHHHHHHHHHHHHCCCCEEHHCCHHHHHHHHHHCCCCHHEE
IGIRDDLIAAGALYEDRPVVVDGNVITSRMPDDLPYFCGELIKILKRY
ECCCHHHHHHCCEECCCCEEEECCEEECCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475