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The map label for this gene is gctA

Identifier: 11498798

GI number: 11498798

Start: 1070406

End: 1071749

Strand: Reverse

Name: gctA

Synonym: AF1199

Alternate gene names: 11498798

Gene position: 1071749-1070406 (Counterclockwise)

Preceding gene: 11498799

Following gene: 11498797

Centisome position: 49.2

GC content: 53.05

Gene sequence:

>1344_bases
ATGGCACCACCCCGGTGCAGACGAGAGAAACTCAATTCTACCGTGGCTGAAGGAGGAGTACAAGCAGCTGACGGGCAGAG
ATGTCAGCGAGGACTTCCCTTACTGGGAGCCGTGCCACAGGCTGCTCCTTACACACGGAATAATGGGATGGGAGAATGTA
GGAGGGGACATCGACAAGGTCACAGGGCAGAGGTGCACGATAATCGGCCTGCCGATAAGGTGGGTCAAGGGAGATGGCTC
AATAGTCAGACTCGTCGCCCTTGTCGAAAAGAGGTAACCTCTTTTCAATTTTTCCCGTTTCTGATTTTTCACACAGGAGG
TGCAGAGATGGAACCTCTGGAAATTATGGATGAAGGCGAAGGCCCCCTCGTTGGCTGGTGTGACCCTGACGAGTTCCGGG
AGTGGGTGAGGGACAACAAGAGCAGAGAGATGGCTGACAAGACGATGTCCGCAGAAGAGGCGGTTTCGAACTTCATCAAA
GATGGCATGTACGTCGCCAGCGGGGGATTCGGGCATGTAAGGGTTTCCATGAACATCATTTATGAAATCATCAGGCAGGG
AGTAAAGGGACTTACGATGGCGGGAAAGACCTCGGTGCACGACCTCGATGTGCTGATGGCTGCCGGCTGCGTTGAAAAGG
TTGAGGCTGCATACAGCTTTGGCCACGAGCTGAGGGGGCTGTCGCCCGCTTCGAGAAGGAAGGTTGAGGGTGGGGAGGTA
AAGGTTATCACCGAGTGGAGCAACGCAGCTTTGCAATGGAGGTTCAAAGCAGCGGCAATGGGTCTTCCCTTCATTCCAGC
AAGGATTTTGATGGGAACGGACACGTTCAAAAAGAGTTCTGCCAAAATCATCAGAGACCCATACAGCGGAAAGCCCGTCA
CCTTGATTCCGGCCTGCTTCCCCGATGTGGCCATAATACACGTTCACCGTGCCGACAAATACGGAAATGCTCAGATTGAT
GGAATCCTTGTTGAAGACTACGAGCTTGCGAGGGCAGCGAAGAGGCTGATAGTCACAACCGAGGAGATAGTCCCGACGGA
CAAAATCAGGGAGAGTCCGTGGAGAACCTCCATCCCCTACTTCCTTGTGGATGCCGTTGTAGAGCAGCCCTTTGCGTCCC
ATCCCTGTAATATGCCTTTGCTCTACTACTTTGACGAGGAGCACATTGCCGAGTATCTTGCATTGACGAGAACGGAGGAG
GGAGCCAAGGAGTACTTTGAAAAGTACGTTTATGGAGTCAACGATTTCTGGGAGTACCTCGAAGTTGTCGGTGGTTCTAA
GAGGCTCGAAAAACTCAGAAGGATTGAGCAGCTCAGGGAGCGCCCTGTTTACCCGTGGAGGTGA

Upstream 100 bases:

>100_bases
GATTTTACAAGGAGGCAGGTGAGTGGTTCGTTAAAAAGAAGGTTAAGGCCGTGGGAATTGACACTCAGGCTCTCGACCAC
CCCCTTGCAACGAGAGAAGC

Downstream 100 bases:

>100_bases
TAATCTTGGTGGAGTATTCTGATACCGAGTACATGGTTTGTGTCGCCGCAAGAATTCTCGAAGACCGAAAAAGTGTGTTT
GTGGGGACAGGAATGCCTGT

Product: glutaconate CoA-transferase, subunit A (gctA)

Products: acetate; glutaconyl-1-CoA

Alternate protein names: NA

Number of amino acids: Translated: 447; Mature: 446

Protein sequence:

>447_residues
MAPPRCRREKLNSTVAEGGVQAADGQRCQRGLPLLGAVPQAAPYTRNNGMGECRRGHRQGHRAEVHDNRPADKVGQGRWL
NSQTRRPCRKEVTSFQFFPFLIFHTGGAEMEPLEIMDEGEGPLVGWCDPDEFREWVRDNKSREMADKTMSAEEAVSNFIK
DGMYVASGGFGHVRVSMNIIYEIIRQGVKGLTMAGKTSVHDLDVLMAAGCVEKVEAAYSFGHELRGLSPASRRKVEGGEV
KVITEWSNAALQWRFKAAAMGLPFIPARILMGTDTFKKSSAKIIRDPYSGKPVTLIPACFPDVAIIHVHRADKYGNAQID
GILVEDYELARAAKRLIVTTEEIVPTDKIRESPWRTSIPYFLVDAVVEQPFASHPCNMPLLYYFDEEHIAEYLALTRTEE
GAKEYFEKYVYGVNDFWEYLEVVGGSKRLEKLRRIEQLRERPVYPWR

Sequences:

>Translated_447_residues
MAPPRCRREKLNSTVAEGGVQAADGQRCQRGLPLLGAVPQAAPYTRNNGMGECRRGHRQGHRAEVHDNRPADKVGQGRWL
NSQTRRPCRKEVTSFQFFPFLIFHTGGAEMEPLEIMDEGEGPLVGWCDPDEFREWVRDNKSREMADKTMSAEEAVSNFIK
DGMYVASGGFGHVRVSMNIIYEIIRQGVKGLTMAGKTSVHDLDVLMAAGCVEKVEAAYSFGHELRGLSPASRRKVEGGEV
KVITEWSNAALQWRFKAAAMGLPFIPARILMGTDTFKKSSAKIIRDPYSGKPVTLIPACFPDVAIIHVHRADKYGNAQID
GILVEDYELARAAKRLIVTTEEIVPTDKIRESPWRTSIPYFLVDAVVEQPFASHPCNMPLLYYFDEEHIAEYLALTRTEE
GAKEYFEKYVYGVNDFWEYLEVVGGSKRLEKLRRIEQLRERPVYPWR
>Mature_446_residues
APPRCRREKLNSTVAEGGVQAADGQRCQRGLPLLGAVPQAAPYTRNNGMGECRRGHRQGHRAEVHDNRPADKVGQGRWLN
SQTRRPCRKEVTSFQFFPFLIFHTGGAEMEPLEIMDEGEGPLVGWCDPDEFREWVRDNKSREMADKTMSAEEAVSNFIKD
GMYVASGGFGHVRVSMNIIYEIIRQGVKGLTMAGKTSVHDLDVLMAAGCVEKVEAAYSFGHELRGLSPASRRKVEGGEVK
VITEWSNAALQWRFKAAAMGLPFIPARILMGTDTFKKSSAKIIRDPYSGKPVTLIPACFPDVAIIHVHRADKYGNAQIDG
ILVEDYELARAAKRLIVTTEEIVPTDKIRESPWRTSIPYFLVDAVVEQPFASHPCNMPLLYYFDEEHIAEYLALTRTEEG
AKEYFEKYVYGVNDFWEYLEVVGGSKRLEKLRRIEQLRERPVYPWR

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG1788

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit A family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y1199_ARCFU (O29069)

Other databases:

- EMBL:   AE000782
- PIR:   F69399
- RefSeq:   NP_070027.1
- ProteinModelPortal:   O29069
- SMR:   O29069
- GeneID:   1484423
- GenomeReviews:   AE000782_GR
- KEGG:   afu:AF1199
- NMPDR:   fig|224325.1.peg.1187
- TIGR:   AF_1199
- HOGENOM:   HBG615556
- OMA:   ELEEYSH
- ProtClustDB:   CLSK541670
- BioCyc:   AFUL224325:AF_1199-MONOMER
- InterPro:   IPR004165
- PANTHER:   PTHR13707
- SMART:   SM00882

Pfam domain/function: PF01144 CoA_trans

EC number: 2.8.3.12

Molecular weight: Translated: 50531; Mature: 50400

Theoretical pI: Translated: 7.54; Mature: 7.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPPRCRREKLNSTVAEGGVQAADGQRCQRGLPLLGAVPQAAPYTRNNGMGECRRGHRQG
CCCCHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCC
HRAEVHDNRPADKVGQGRWLNSQTRRPCRKEVTSFQFFPFLIFHTGGAEMEPLEIMDEGE
CCCCCCCCCCHHHHCCCCCCCHHHCCHHHHHHHHHHHEEEEEEECCCCCCCCHHHEECCC
GPLVGWCDPDEFREWVRDNKSREMADKTMSAEEAVSNFIKDGMYVASGGFGHVRVSMNII
CCEEECCCHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHCCEEEECCCCCEEEEHHHHH
YEIIRQGVKGLTMAGKTSVHDLDVLMAAGCVEKVEAAYSFGHELRGLSPASRRKVEGGEV
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCE
KVITEWSNAALQWRFKAAAMGLPFIPARILMGTDTFKKSSAKIIRDPYSGKPVTLIPACF
EEEEECCCCEEEEEEHHHHCCCCCCCHHHHCCCCHHHHCCCHHEECCCCCCCEEEECCCC
PDVAIIHVHRADKYGNAQIDGILVEDYELARAAKRLIVTTEEIVPTDKIRESPWRTSIPY
CCEEEEEEEECCCCCCCEECEEEECCHHHHHHHHHHHEEHHHHCCCHHHHCCCCCCCCHH
FLVDAVVEQPFASHPCNMPLLYYFDEEHIAEYLALTRTEEGAKEYFEKYVYGVNDFWEYL
HHHHHHHHCCCCCCCCCCCEEEEECHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHH
EVVGGSKRLEKLRRIEQLRERPVYPWR
HHHCCHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
APPRCRREKLNSTVAEGGVQAADGQRCQRGLPLLGAVPQAAPYTRNNGMGECRRGHRQG
CCCHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCC
HRAEVHDNRPADKVGQGRWLNSQTRRPCRKEVTSFQFFPFLIFHTGGAEMEPLEIMDEGE
CCCCCCCCCCHHHHCCCCCCCHHHCCHHHHHHHHHHHEEEEEEECCCCCCCCHHHEECCC
GPLVGWCDPDEFREWVRDNKSREMADKTMSAEEAVSNFIKDGMYVASGGFGHVRVSMNII
CCEEECCCHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHCCEEEECCCCCEEEEHHHHH
YEIIRQGVKGLTMAGKTSVHDLDVLMAAGCVEKVEAAYSFGHELRGLSPASRRKVEGGEV
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCE
KVITEWSNAALQWRFKAAAMGLPFIPARILMGTDTFKKSSAKIIRDPYSGKPVTLIPACF
EEEEECCCCEEEEEEHHHHCCCCCCCHHHHCCCCHHHHCCCHHEECCCCCCCEEEECCCC
PDVAIIHVHRADKYGNAQIDGILVEDYELARAAKRLIVTTEEIVPTDKIRESPWRTSIPY
CCEEEEEEEECCCCCCCEECEEEECCHHHHHHHHHHHEEHHHHCCCHHHHCCCCCCCCHH
FLVDAVVEQPFASHPCNMPLLYYFDEEHIAEYLALTRTEEGAKEYFEKYVYGVNDFWEYL
HHHHHHHHCCCCCCCCCCCEEEEECHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHH
EVVGGSKRLEKLRRIEQLRERPVYPWR
HHHCCHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acetyl-CoA; (E)-glutaconate

Specific reaction: acetyl-CoA + (E)-glutaconate = acetate + glutaconyl-1-CoA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9389475