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The map label for this gene is acaB-10

Identifier: 11498573

GI number: 11498573

Start: 867593

End: 868759

Strand: Reverse

Name: acaB-10

Synonym: AF0968

Alternate gene names: NA

Gene position: 868759-867593 (Counterclockwise)

Preceding gene: 11498574

Following gene: 11498572

Centisome position: 39.88

GC content: 53.38

Gene sequence:

>1167_bases
ATGCAAAGAATAATTGGTGATGGAATGGTAGCTGTTGTGGGAGTTGGTTATGCGGGTTTCAACTCCACCACGCCCGACCT
GAGCTGGAAAGAAATTATGTACGAGGCTGCGGTCAGAGCCTACACCGATGCTGGCATAAATCCGCGCAGGGATGTGGACA
GCTTTGTAACGTGTGCTGAGGACATATACGAGGGCTTTGCCATTTTCGACGAGTTCGTCCCGGACCAGCTCGGAGCGGTG
GTGAAGCCGACGTGCACCGTAACGGCAGACTTCCTCTATGGCGTTGCGACGGCATACATGCACATAAACAGTGGGCTGGC
GGACATCGCAGTTGTTGAAGCCCACAGCAAGGCGAGTGACATTCAGACATTTGGCAATGTTGTTAAGTTTGCGATGGACC
CGATATGGCTGAGGAACGTTGGAAATGCCCATCCATATTACCTCGCTGCTCTCGAAATGTTCCAGTACATGGCTGAGAGG
TGTCTCAGCGAGGAAGACGTGGCAAGGGTTGTAGTGAAGAACAAGAACAACGCCCTGCTCAATCCTGCAGCCCCTTACGC
TGCAAACGTAACTCTTGACGACGTCATGGCGAGCCCTAAGCTCTTTGACCCCATGAAAAAGATGGAAATAGCTCCTCTTG
CTGACGGCTGTGTTGTCTTTGTCCTTGCAAGCGATGAGGTGGCGAGGAAGCTGACAGACAACCCAGTCTGGGTTAAGGGA
ATTGGATGGTGGAGCGAAACCTACGGCTACGATACTGCGAGCTTCTCTGCAATGTATGCCTACAAGGCAGCAAAGATGGC
CTACAAGATGGCGGGAATAGCCAATCCCGCCAAGGAGGTGGACTTTGCTGAGGTTGACGACAGGTTTGCCTTCAAGGAGA
TGCAGCACATCGAAGCATTGCAGCTTGCTGGCAAATTCGACGTTGCAAGGCTTATGGCTGAGGGCTACTTCGACAGGGAT
GGTGCCAAGCCGGTAAACGTTTCTGGAGGAAGTCTGGGAGTTGGCAATCTGCTGGAGTGCACAGGAGGGCAGAAAGCTTT
AGAGGTGGTTCTGCAGCTTCGCGGTGAAGCGGGCAAGAGGCAGCTTAGCGATGTGGAGGTTGGAGTGGCTCAGGCATGGC
GCTACCTGCCGACGCACAGCGGTGCTGTAGCAGTTTTTGGTGTGTAA

Upstream 100 bases:

>100_bases
TAAAAATTGAATATATCAAGTATTAATTGGAACAAATTCGGTACAGGCGGATTATCTATTTTTAAATCGGCACATTACGT
AAAATTTAAGTATTAACGAA

Downstream 100 bases:

>100_bases
GGTGGTGGTTATGGAAGTTGAGAGGATAAGCGGTTTGAAGTTTCACAAGAAGCAGGATGTGGCCATTGTAGGAGCGGGAA
TGACCACCTTCAAGAGGAGG

Product: acetyl-CoA acetyltransferase

Products: CoA; 3-oxoacyl-CoA

Alternate protein names: NA

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MQRIIGDGMVAVVGVGYAGFNSTTPDLSWKEIMYEAAVRAYTDAGINPRRDVDSFVTCAEDIYEGFAIFDEFVPDQLGAV
VKPTCTVTADFLYGVATAYMHINSGLADIAVVEAHSKASDIQTFGNVVKFAMDPIWLRNVGNAHPYYLAALEMFQYMAER
CLSEEDVARVVVKNKNNALLNPAAPYAANVTLDDVMASPKLFDPMKKMEIAPLADGCVVFVLASDEVARKLTDNPVWVKG
IGWWSETYGYDTASFSAMYAYKAAKMAYKMAGIANPAKEVDFAEVDDRFAFKEMQHIEALQLAGKFDVARLMAEGYFDRD
GAKPVNVSGGSLGVGNLLECTGGQKALEVVLQLRGEAGKRQLSDVEVGVAQAWRYLPTHSGAVAVFGV

Sequences:

>Translated_388_residues
MQRIIGDGMVAVVGVGYAGFNSTTPDLSWKEIMYEAAVRAYTDAGINPRRDVDSFVTCAEDIYEGFAIFDEFVPDQLGAV
VKPTCTVTADFLYGVATAYMHINSGLADIAVVEAHSKASDIQTFGNVVKFAMDPIWLRNVGNAHPYYLAALEMFQYMAER
CLSEEDVARVVVKNKNNALLNPAAPYAANVTLDDVMASPKLFDPMKKMEIAPLADGCVVFVLASDEVARKLTDNPVWVKG
IGWWSETYGYDTASFSAMYAYKAAKMAYKMAGIANPAKEVDFAEVDDRFAFKEMQHIEALQLAGKFDVARLMAEGYFDRD
GAKPVNVSGGSLGVGNLLECTGGQKALEVVLQLRGEAGKRQLSDVEVGVAQAWRYLPTHSGAVAVFGV
>Mature_388_residues
MQRIIGDGMVAVVGVGYAGFNSTTPDLSWKEIMYEAAVRAYTDAGINPRRDVDSFVTCAEDIYEGFAIFDEFVPDQLGAV
VKPTCTVTADFLYGVATAYMHINSGLADIAVVEAHSKASDIQTFGNVVKFAMDPIWLRNVGNAHPYYLAALEMFQYMAER
CLSEEDVARVVVKNKNNALLNPAAPYAANVTLDDVMASPKLFDPMKKMEIAPLADGCVVFVLASDEVARKLTDNPVWVKG
IGWWSETYGYDTASFSAMYAYKAAKMAYKMAGIANPAKEVDFAEVDDRFAFKEMQHIEALQLAGKFDVARLMAEGYFDRD
GAKPVNVSGGSLGVGNLLECTGGQKALEVVLQLRGEAGKRQLSDVEVGVAQAWRYLPTHSGAVAVFGV

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI19923233, Length=386, Percent_Identity=26.4248704663212, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI302344760, Length=242, Percent_Identity=28.5123966942149, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI302344762, Length=242, Percent_Identity=28.5123966942149, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI302344767, Length=242, Percent_Identity=28.5123966942149, Blast_Score=79, Evalue=8e-15,
Organism=Drosophila melanogaster, GI24585051, Length=406, Percent_Identity=24.384236453202, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI19921506, Length=406, Percent_Identity=23.3990147783251, Blast_Score=72, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002155
- InterPro:   IPR016039
- InterPro:   IPR016038
- InterPro:   IPR020617
- InterPro:   IPR020616 [H]

Pfam domain/function: PF02803 Thiolase_C; PF00108 Thiolase_N [H]

EC number: 2.3.1.16

Molecular weight: Translated: 42181; Mature: 42181

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRIIGDGMVAVVGVGYAGFNSTTPDLSWKEIMYEAAVRAYTDAGINPRRDVDSFVTCAE
CCCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
DIYEGFAIFDEFVPDQLGAVVKPTCTVTADFLYGVATAYMHINSGLADIAVVEAHSKASD
HHHHHHHHHHHHCHHHHCCEECCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHH
IQTFGNVVKFAMDPIWLRNVGNAHPYYLAALEMFQYMAERCLSEEDVARVVVKNKNNALL
HHHHHHHHHHHHCCHHHHCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHEEEEECCCCEEE
NPAAPYAANVTLDDVMASPKLFDPMKKMEIAPLADGCVVFVLASDEVARKLTDNPVWVKG
CCCCCCCCCCCHHHHHCCCHHHCHHHHCCCCCCCCCEEEEEECCHHHHHHHCCCCEEEEE
IGWWSETYGYDTASFSAMYAYKAAKMAYKMAGIANPAKEVDFAEVDDRFAFKEMQHIEAL
ECCHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHHHHHHHHH
QLAGKFDVARLMAEGYFDRDGAKPVNVSGGSLGVGNLLECTGGQKALEVVLQLRGEAGKR
HHCCHHHHHHHHHCCCCCCCCCCEEECCCCCCCCCCHHCCCCCHHHHHHHHHHHCCCCHH
QLSDVEVGVAQAWRYLPTHSGAVAVFGV
HHHHHHHHHHHHHHHCCCCCCCEEEEEC
>Mature Secondary Structure
MQRIIGDGMVAVVGVGYAGFNSTTPDLSWKEIMYEAAVRAYTDAGINPRRDVDSFVTCAE
CCCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
DIYEGFAIFDEFVPDQLGAVVKPTCTVTADFLYGVATAYMHINSGLADIAVVEAHSKASD
HHHHHHHHHHHHCHHHHCCEECCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHH
IQTFGNVVKFAMDPIWLRNVGNAHPYYLAALEMFQYMAERCLSEEDVARVVVKNKNNALL
HHHHHHHHHHHHCCHHHHCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHEEEEECCCCEEE
NPAAPYAANVTLDDVMASPKLFDPMKKMEIAPLADGCVVFVLASDEVARKLTDNPVWVKG
CCCCCCCCCCCHHHHHCCCHHHCHHHHCCCCCCCCCEEEEEECCHHHHHHHCCCCEEEEE
IGWWSETYGYDTASFSAMYAYKAAKMAYKMAGIANPAKEVDFAEVDDRFAFKEMQHIEAL
ECCHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHHHHHHHHH
QLAGKFDVARLMAEGYFDRDGAKPVNVSGGSLGVGNLLECTGGQKALEVVLQLRGEAGKR
HHCCHHHHHHHHHCCCCCCCCCCEEECCCCCCCCCCHHCCCCCHHHHHHHHHHHCCCCHH
QLSDVEVGVAQAWRYLPTHSGAVAVFGV
HHHHHHHHHHHHHHHCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acetyl-CoA

Specific reaction: acyl-CoA + acetyl-CoA = CoA + 3-oxoacyl-CoA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]