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The map label for this gene is acaB-9

Identifier: 11498572

GI number: 11498572

Start: 866380

End: 867582

Strand: Reverse

Name: acaB-9

Synonym: AF0967

Alternate gene names: NA

Gene position: 867582-866380 (Counterclockwise)

Preceding gene: 11498573

Following gene: 11498571

Centisome position: 39.83

GC content: 54.03

Gene sequence:

>1203_bases
ATGGAAGTTGAGAGGATAAGCGGTTTGAAGTTTCACAAGAAGCAGGATGTGGCCATTGTAGGAGCGGGAATGACCACCTT
CAAGAGGAGGCTCAATGAAACGGGAAGAGAGCTGAGCTACCTTGCTGTAAAGCAGGCTTTAGAGGAGGCTGGCCTTACGA
TTGACGACATTGAGATGGTGGTGATGGGCTCTGCACCAGACGCCTTCGATGGCTTCCACATGAAGGGAGAGTACCTGCTC
GACGGCTCTGGTGGGAGTAACCGCCCTTACATGAGAGTTTTCGTCGGTGGTGGAACTGGAGTCTTTGCCCCAATCGCTGG
CTACTGGCACGTTGCAAGCGGTTTAGCTGATGTCTGCCTTGTCGTTTGCGAGGAGAAGATGTCTTCAGTCCATCCCCATC
CCCAGTCGGCTTTCAAGTACATCTGGGACCCCATCCTCGACCGCCCGCTTAACCCCAACCTGATATGGATTTTCGCACTC
GAAATGCGCCGATACATGCACGTCCACAACATAAAGCACGAGGATATCGCTTTGGTTTCTGTCAAGAACAAGGCAAATGC
TTTGGATCATCCGTGTGCTCAGGTGGCGGAAAAGATTACTGTTGAGGATGTTCTCAACAGCGAGCCGATGGCATTGCCCG
TGAGAAGGCTCGACGTCTCACCGCCATCAGACGGAGCTGCAGCGCTGATAATGGTCGCCCCGCACATTGCGAGGCAGCTA
ACCGACAACCCAGTCTGGGTGACGGGAGTTGGCTGGGCCCTCGACACGACCTGGTGGACCAACAGAGACCTCTACTTCCC
GCGCTATGTGGCTGAGGCTGCGAAGATGGCTTACAGGATGGCCCACATCACTGACCCAAGAAAGGAGATTGACGTTGCTG
AACCCTACGACCCCTTCGACTACAAGGAGCTGCACCACATGGAGGGATTGGGATTGGCGAAGAAAGGTGAGGCTCCAATT
CTGACAAGGGAAGGAGTTACGCAGAGAGACGGTGACTTGCCCACCTGCCCGTCAGGAGGTCTGCTTGGTGTTGGAAATCC
AATTGCAGCTACAATGGGTGTTAAGGCGTGCGAAATCTACTGGCAGCTCGCCTACAGGGCTGGAAAGAGACAGGTGGCGA
AGGAAGTCACAACAGGAGTATGTCAGGCATGGGGAGACCTGATGCAGGTTGGAACTGTTATGGTTATGTCTAACAAGAGG
TGA

Upstream 100 bases:

>100_bases
AGGCAGCTTAGCGATGTGGAGGTTGGAGTGGCTCAGGCATGGCGCTACCTGCCGACGCACAGCGGTGCTGTAGCAGTTTT
TGGTGTGTAAGGTGGTGGTT

Downstream 100 bases:

>100_bases
TAGGATGGCTGTAGGCAAAAAGGATATTGAGTGCCCTCCCTATGCTGAAGGCACACCGCTAAGCGATGCGGATATCAAGG
AAAAGAGGGTTACCTACGTT

Product: acetyl-CoA acetyltransferase

Products: CoA; 3-oxoacyl-CoA

Alternate protein names: NA

Number of amino acids: Translated: 400; Mature: 400

Protein sequence:

>400_residues
MEVERISGLKFHKKQDVAIVGAGMTTFKRRLNETGRELSYLAVKQALEEAGLTIDDIEMVVMGSAPDAFDGFHMKGEYLL
DGSGGSNRPYMRVFVGGGTGVFAPIAGYWHVASGLADVCLVVCEEKMSSVHPHPQSAFKYIWDPILDRPLNPNLIWIFAL
EMRRYMHVHNIKHEDIALVSVKNKANALDHPCAQVAEKITVEDVLNSEPMALPVRRLDVSPPSDGAAALIMVAPHIARQL
TDNPVWVTGVGWALDTTWWTNRDLYFPRYVAEAAKMAYRMAHITDPRKEIDVAEPYDPFDYKELHHMEGLGLAKKGEAPI
LTREGVTQRDGDLPTCPSGGLLGVGNPIAATMGVKACEIYWQLAYRAGKRQVAKEVTTGVCQAWGDLMQVGTVMVMSNKR

Sequences:

>Translated_400_residues
MEVERISGLKFHKKQDVAIVGAGMTTFKRRLNETGRELSYLAVKQALEEAGLTIDDIEMVVMGSAPDAFDGFHMKGEYLL
DGSGGSNRPYMRVFVGGGTGVFAPIAGYWHVASGLADVCLVVCEEKMSSVHPHPQSAFKYIWDPILDRPLNPNLIWIFAL
EMRRYMHVHNIKHEDIALVSVKNKANALDHPCAQVAEKITVEDVLNSEPMALPVRRLDVSPPSDGAAALIMVAPHIARQL
TDNPVWVTGVGWALDTTWWTNRDLYFPRYVAEAAKMAYRMAHITDPRKEIDVAEPYDPFDYKELHHMEGLGLAKKGEAPI
LTREGVTQRDGDLPTCPSGGLLGVGNPIAATMGVKACEIYWQLAYRAGKRQVAKEVTTGVCQAWGDLMQVGTVMVMSNKR
>Mature_400_residues
MEVERISGLKFHKKQDVAIVGAGMTTFKRRLNETGRELSYLAVKQALEEAGLTIDDIEMVVMGSAPDAFDGFHMKGEYLL
DGSGGSNRPYMRVFVGGGTGVFAPIAGYWHVASGLADVCLVVCEEKMSSVHPHPQSAFKYIWDPILDRPLNPNLIWIFAL
EMRRYMHVHNIKHEDIALVSVKNKANALDHPCAQVAEKITVEDVLNSEPMALPVRRLDVSPPSDGAAALIMVAPHIARQL
TDNPVWVTGVGWALDTTWWTNRDLYFPRYVAEAAKMAYRMAHITDPRKEIDVAEPYDPFDYKELHHMEGLGLAKKGEAPI
LTREGVTQRDGDLPTCPSGGLLGVGNPIAATMGVKACEIYWQLAYRAGKRQVAKEVTTGVCQAWGDLMQVGTVMVMSNKR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI19923233, Length=373, Percent_Identity=26.2734584450402, Blast_Score=89, Evalue=9e-18,
Organism=Homo sapiens, GI302344760, Length=370, Percent_Identity=26.2162162162162, Blast_Score=82, Evalue=8e-16,
Organism=Homo sapiens, GI302344767, Length=298, Percent_Identity=26.8456375838926, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI302344762, Length=230, Percent_Identity=28.2608695652174, Blast_Score=78, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17537653, Length=386, Percent_Identity=25.1295336787565, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI19921506, Length=382, Percent_Identity=25.3926701570681, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24585051, Length=382, Percent_Identity=25.9162303664921, Blast_Score=95, Evalue=9e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002155
- InterPro:   IPR016039
- InterPro:   IPR016038
- InterPro:   IPR020617
- InterPro:   IPR020616 [H]

Pfam domain/function: PF02803 Thiolase_C; PF00108 Thiolase_N [H]

EC number: 2.3.1.16

Molecular weight: Translated: 44216; Mature: 44216

Theoretical pI: Translated: 6.57; Mature: 6.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEVERISGLKFHKKQDVAIVGAGMTTFKRRLNETGRELSYLAVKQALEEAGLTIDDIEMV
CCCCCCCCCCEECCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECEEEE
VMGSAPDAFDGFHMKGEYLLDGSGGSNRPYMRVFVGGGTGVFAPIAGYWHVASGLADVCL
EECCCCCCCCCCEECCCEEEECCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHH
VVCEEKMSSVHPHPQSAFKYIWDPILDRPLNPNLIWIFALEMRRYMHVHNIKHEDIALVS
HHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHHCCCCCCEEEEE
VKNKANALDHPCAQVAEKITVEDVLNSEPMALPVRRLDVSPPSDGAAALIMVAPHIARQL
ECCCCCCCCCHHHHHHHHHHHHHHHCCCCCEECCEEEECCCCCCCCEEEEEECHHHHHHH
TDNPVWVTGVGWALDTTWWTNRDLYFPRYVAEAAKMAYRMAHITDPRKEIDVAEPYDPFD
CCCCEEEEEECCEEECCEECCCCCCCHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCC
YKELHHMEGLGLAKKGEAPILTREGVTQRDGDLPTCPSGGLLGVGNPIAATMGVKACEIY
HHHHHHHCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCEEECCCCHHHHHCCHHHHHH
WQLAYRAGKRQVAKEVTTGVCQAWGDLMQVGTVMVMSNKR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCC
>Mature Secondary Structure
MEVERISGLKFHKKQDVAIVGAGMTTFKRRLNETGRELSYLAVKQALEEAGLTIDDIEMV
CCCCCCCCCCEECCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECEEEE
VMGSAPDAFDGFHMKGEYLLDGSGGSNRPYMRVFVGGGTGVFAPIAGYWHVASGLADVCL
EECCCCCCCCCCEECCCEEEECCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHH
VVCEEKMSSVHPHPQSAFKYIWDPILDRPLNPNLIWIFALEMRRYMHVHNIKHEDIALVS
HHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHHCCCCCCEEEEE
VKNKANALDHPCAQVAEKITVEDVLNSEPMALPVRRLDVSPPSDGAAALIMVAPHIARQL
ECCCCCCCCCHHHHHHHHHHHHHHHCCCCCEECCEEEECCCCCCCCEEEEEECHHHHHHH
TDNPVWVTGVGWALDTTWWTNRDLYFPRYVAEAAKMAYRMAHITDPRKEIDVAEPYDPFD
CCCCEEEEEECCEEECCEECCCCCCCHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCC
YKELHHMEGLGLAKKGEAPILTREGVTQRDGDLPTCPSGGLLGVGNPIAATMGVKACEIY
HHHHHHHCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCEEECCCCHHHHHCCHHHHHH
WQLAYRAGKRQVAKEVTTGVCQAWGDLMQVGTVMVMSNKR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acetyl-CoA

Specific reaction: acyl-CoA + acetyl-CoA = CoA + 3-oxoacyl-CoA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]