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Identifier: 11498270

GI number: 11498270

Start: 596484

End: 598727

Strand: Reverse

Name: Not Available

Synonym: AF0662

Alternate gene names: 11498270

Gene position: 598727-596484 (Counterclockwise)

Preceding gene: 11498271

Following gene: 11498269

Centisome position: 27.48

GC content: 51.38

Gene sequence:

>2244_bases
ATGATGGAGAAAGTTGGTGTTTACATCTGTACCGGTTGTGATATCGATAAGCTGGACATCGAAAGGCTGAAAAACGTTGC
AAAGGAGGAGTTTGGAATTGAGGCAAAGATCCATCCGCACCTCTGCTCGCAGGAAGGAGTTGAAATGCTCAAGAACGATG
CTGCGGAGCTTGACGCTCTTGTAATTGCAGCATGCTCACCCCGTGTGAAAACGGCCCTCTTCACCTTCGATGACAAGTAC
GTTGAGAGGGCGAGTCTCAGAGAGGGAGTTGTCTGGAGCCACGACATTGATGAGCACGCTCAGGAGCTTGCCGAGGATTA
CCTGAGAATTGCCATCACCAAAGCCCAGAAGGCTGAAAAGCCCGAGCCATACATTGAGGAGGTATCGAAGGACATCCTCG
TCGTTGGCGGTGGTGTTACAGGCTTAACCGCCGCTCTTGAGGTTGCAAAGGCGGGTTACAAAGCCCATCTTGTGGAGAAG
GAGGCCGAGCTCGGAGGATGGGTGGCCAAATACTACAAAACTCTGCCCGTTGAGCCGCCATACACGAGAATTGAGGAGAA
TCCTGTATTCCAGCTAATTGATGAGGTAAAGAGTAATGGAAACATAGAGGTTTACACCTCCGCAGAGATTGACTCAATCA
GCGGCCAGCCGGGAATGTTCGACGTTGTGCTAAACAAGGATGGAGAGAAGGTGCAGTTCAGAGTTGGAGGAATTGTTGTC
GCAACCGGCTGGAAGCCTTACGACGCCTCAGCTTTAGAGGAGCTTGGCTATGGGAAGTTTGCCGACGTCGTCACAAACCT
TGAGTTCGAGGAGATGGCAAAGGAGGGCAAAATCCTCAGAAAGTCTGATGGAAGCGAGGCGAAGAATGTGGTGTTTATCC
AGTGCGCAGGGCAGAGAGACGAGAACCACCTGCCTTACTGCTCATCCGTCTGCTGCCTCGTGAGCCTTAAGCAGGCAAAG
TACGTGAGGGAGCTTACCAATGGCAATGCCTTCATAATCTACAAGGACATGAGAACTCCAGGACTTTGGGAGGATTTCTA
CAAGGAAATGCAGCAGGACGATGGAATTTTCCTGACGAAGGGTGACATCAAGGAAATCAAAGAAGAGGGTGGAAAGCTGA
CGGTTGTCGTGACCAACACGCTACTTGGAGAGGACATTGCAATTAAAGCTGATTTGATCGTGCTCGCAACGGGAATGGTC
TCAACGCTGAAGGGACTTTATACGGTAAAGGAAGAATTCCCGGATGAAAAGACCGTGCCTTACAAGCACATTTCCGAGCC
GCATTTGATTAAGAGCGAGGAGGATGTTGAAGTAATCAAGCAGGCCGGGCATATACTCAACCTGCAGTACAGGCAGGGTC
CCGAGCTTCCCACGCTGAAGTACGGGTTCCCCGACTCCAACTACATCTGCTTCCCCTATGAGAGCAGGAGGCTTGGAATT
TACGCTGCCGGAGCTGTCAGGGCACCAATGGAGATTGCCTCATGCATTGAAGATGCGAAGGGAGCAGCCTTAAAGGCGAT
TCAGGCGGTTGAGCTCGTTGCTGAAGGTAAAACGACTTTCCCGAGAACTGGAGATATCGACTACCCGCAGTTCTTCCTCC
AGCGCTGCACTCAGTGTAAGAGGTGTACTGAAGAGTGCCCCTTTGGTGCACTTGATGAGGATGAGAAGGGCACTCCGATG
CCCAATCCGCTGAGGTGCAGGAGATGTGGTATCTGCTTCGGTGCCTGTCCTGAGAGAATCATCAGCTTCAAGACCTACAG
CATCGACCAGATGGCGTCAGCGGTTAAGTCAATCTACGTCCCTGATCCCAACTGGGATGAGGGGGCTGAGGACAAGTTCC
GCTTCATAGTCTTCGCCTGCGAGAATGACGCTTTGCCAGCTTTGGACATGTCCGCTCTGAACGGAAAGAAGTGGAGCCCG
CTTGCCAGAATCATCCCGGTGAGGTGCCTCGGTTCGGTCAACACCGTCTTTATCGCAGACGCACTCTCAAAGGGTATTGA
TGGGATTCTGCTTGTAGGATGTAAGTACGGAGAGGACTACCAGTGCCACTTCATCAGGGGAAGTGAGCTTGCCAACAGAA
GAATGGAGAATGTGGCAGAGACTCTTGAGAGGCTGATGCTGGAGAAGGAGAGAGTGCAGGTGGTGGAAATCTCTATAAAC
GAGTGGGACAAGATTACAGAGATTATAGACAACTTCGTCAACCAGATCATGGAGATTGGTGCGAACCCGTATAAGGGGTT
CTGA

Upstream 100 bases:

>100_bases
ATTCCGGTAGGTGTTGCGGCGATGCCCATGGAGGTCGCCTCAGCCAACGAAACCGCAACGGCAGCAGCGCTGAAGGCTAT
TCAGCTTGCAAGGAGGTGAA

Downstream 100 bases:

>100_bases
GGTGGACTATGGAGGTTGATGCGCAGTTCGTCAGGGATGTGATAGGATTTGGAGGTAAGACGCTTAGAAAGTGCTACCAG
TGTGCAACATGCAGCGTCGT

Product: heterodisulfide reductase, subunit A/methylviologen reducing hydrogenase, subunit delta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 747; Mature: 747

Protein sequence:

>747_residues
MMEKVGVYICTGCDIDKLDIERLKNVAKEEFGIEAKIHPHLCSQEGVEMLKNDAAELDALVIAACSPRVKTALFTFDDKY
VERASLREGVVWSHDIDEHAQELAEDYLRIAITKAQKAEKPEPYIEEVSKDILVVGGGVTGLTAALEVAKAGYKAHLVEK
EAELGGWVAKYYKTLPVEPPYTRIEENPVFQLIDEVKSNGNIEVYTSAEIDSISGQPGMFDVVLNKDGEKVQFRVGGIVV
ATGWKPYDASALEELGYGKFADVVTNLEFEEMAKEGKILRKSDGSEAKNVVFIQCAGQRDENHLPYCSSVCCLVSLKQAK
YVRELTNGNAFIIYKDMRTPGLWEDFYKEMQQDDGIFLTKGDIKEIKEEGGKLTVVVTNTLLGEDIAIKADLIVLATGMV
STLKGLYTVKEEFPDEKTVPYKHISEPHLIKSEEDVEVIKQAGHILNLQYRQGPELPTLKYGFPDSNYICFPYESRRLGI
YAAGAVRAPMEIASCIEDAKGAALKAIQAVELVAEGKTTFPRTGDIDYPQFFLQRCTQCKRCTEECPFGALDEDEKGTPM
PNPLRCRRCGICFGACPERIISFKTYSIDQMASAVKSIYVPDPNWDEGAEDKFRFIVFACENDALPALDMSALNGKKWSP
LARIIPVRCLGSVNTVFIADALSKGIDGILLVGCKYGEDYQCHFIRGSELANRRMENVAETLERLMLEKERVQVVEISIN
EWDKITEIIDNFVNQIMEIGANPYKGF

Sequences:

>Translated_747_residues
MMEKVGVYICTGCDIDKLDIERLKNVAKEEFGIEAKIHPHLCSQEGVEMLKNDAAELDALVIAACSPRVKTALFTFDDKY
VERASLREGVVWSHDIDEHAQELAEDYLRIAITKAQKAEKPEPYIEEVSKDILVVGGGVTGLTAALEVAKAGYKAHLVEK
EAELGGWVAKYYKTLPVEPPYTRIEENPVFQLIDEVKSNGNIEVYTSAEIDSISGQPGMFDVVLNKDGEKVQFRVGGIVV
ATGWKPYDASALEELGYGKFADVVTNLEFEEMAKEGKILRKSDGSEAKNVVFIQCAGQRDENHLPYCSSVCCLVSLKQAK
YVRELTNGNAFIIYKDMRTPGLWEDFYKEMQQDDGIFLTKGDIKEIKEEGGKLTVVVTNTLLGEDIAIKADLIVLATGMV
STLKGLYTVKEEFPDEKTVPYKHISEPHLIKSEEDVEVIKQAGHILNLQYRQGPELPTLKYGFPDSNYICFPYESRRLGI
YAAGAVRAPMEIASCIEDAKGAALKAIQAVELVAEGKTTFPRTGDIDYPQFFLQRCTQCKRCTEECPFGALDEDEKGTPM
PNPLRCRRCGICFGACPERIISFKTYSIDQMASAVKSIYVPDPNWDEGAEDKFRFIVFACENDALPALDMSALNGKKWSP
LARIIPVRCLGSVNTVFIADALSKGIDGILLVGCKYGEDYQCHFIRGSELANRRMENVAETLERLMLEKERVQVVEISIN
EWDKITEIIDNFVNQIMEIGANPYKGF
>Mature_747_residues
MMEKVGVYICTGCDIDKLDIERLKNVAKEEFGIEAKIHPHLCSQEGVEMLKNDAAELDALVIAACSPRVKTALFTFDDKY
VERASLREGVVWSHDIDEHAQELAEDYLRIAITKAQKAEKPEPYIEEVSKDILVVGGGVTGLTAALEVAKAGYKAHLVEK
EAELGGWVAKYYKTLPVEPPYTRIEENPVFQLIDEVKSNGNIEVYTSAEIDSISGQPGMFDVVLNKDGEKVQFRVGGIVV
ATGWKPYDASALEELGYGKFADVVTNLEFEEMAKEGKILRKSDGSEAKNVVFIQCAGQRDENHLPYCSSVCCLVSLKQAK
YVRELTNGNAFIIYKDMRTPGLWEDFYKEMQQDDGIFLTKGDIKEIKEEGGKLTVVVTNTLLGEDIAIKADLIVLATGMV
STLKGLYTVKEEFPDEKTVPYKHISEPHLIKSEEDVEVIKQAGHILNLQYRQGPELPTLKYGFPDSNYICFPYESRRLGI
YAAGAVRAPMEIASCIEDAKGAALKAIQAVELVAEGKTTFPRTGDIDYPQFFLQRCTQCKRCTEECPFGALDEDEKGTPM
PNPLRCRRCGICFGACPERIISFKTYSIDQMASAVKSIYVPDPNWDEGAEDKFRFIVFACENDALPALDMSALNGKKWSP
LARIIPVRCLGSVNTVFIADALSKGIDGILLVGCKYGEDYQCHFIRGSELANRRMENVAETLERLMLEKERVQVVEISIN
EWDKITEIIDNFVNQIMEIGANPYKGF

Specific function: Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). May act as the catalytic subunit [H]

COG id: COG1148

COG function: function code C; Heterodisulfide reductase, subunit A and related polyferredoxins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 4 4Fe-4S ferredoxin-type domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001450
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR003953
- InterPro:   IPR003813
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00890 FAD_binding_2; PF00037 Fer4; PF02662 FlpD [H]

EC number: =1.8.98.1 [H]

Molecular weight: Translated: 83310; Mature: 83310

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMEKVGVYICTGCDIDKLDIERLKNVAKEEFGIEAKIHPHLCSQEGVEMLKNDAAELDAL
CCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHCCHHHHHEE
VIAACSPRVKTALFTFDDKYVERASLREGVVWSHDIDEHAQELAEDYLRIAITKAQKAEK
EEEECCCCCEEEEEECCHHHHHHHHHHCCCEECCCHHHHHHHHHHHHHHHHHHHHHCCCC
PEPYIEEVSKDILVVGGGVTGLTAALEVAKAGYKAHLVEKEAELGGWVAKYYKTLPVEPP
CCHHHHHCCCCEEEEECCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
YTRIEENPVFQLIDEVKSNGNIEVYTSAEIDSISGQPGMFDVVLNKDGEKVQFRVGGIVV
CCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCEEEEEECCCCCEEEEEECCEEE
ATGWKPYDASALEELGYGKFADVVTNLEFEEMAKEGKILRKSDGSEAKNVVFIQCAGQRD
ECCCCCCCHHHHHHCCCCHHHHHHHCCCHHHHHHCCCEEECCCCCCCCCEEEEEECCCCC
ENHLPYCSSVCCLVSLKQAKYVRELTNGNAFIIYKDMRTPGLWEDFYKEMQQDDGIFLTK
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHCCCCEEEEC
GDIKEIKEEGGKLTVVVTNTLLGEDIAIKADLIVLATGMVSTLKGLYTVKEEFPDEKTVP
CHHHHHHHCCCEEEEEEECCCCCCCEEEECCHHEEHHHHHHHHHHHHHHHHHCCCCCCCC
YKHISEPHLIKSEEDVEVIKQAGHILNLQYRQGPELPTLKYGFPDSNYICFPYESRRLGI
HHHCCCCCCCCCCHHHHHHHHCCCEEEEEECCCCCCCEEEECCCCCCEEEECCCCCEEEE
YAAGAVRAPMEIASCIEDAKGAALKAIQAVELVAEGKTTFPRTGDIDYPQFFLQRCTQCK
EECCCHHCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHH
RCTEECPFGALDEDEKGTPMPNPLRCRRCGICFGACPERIISFKTYSIDQMASAVKSIYV
HHHHHCCCCCCCCCCCCCCCCCCHHHHHHCCCHHCCHHHHHHHCCCCHHHHHHHHHEEEC
PDPNWDEGAEDKFRFIVFACENDALPALDMSALNGKKWSPLARIIPVRCLGSVNTVFIAD
CCCCCCCCCCCCEEEEEEEECCCCCCCCCHHHCCCCCCCCHHHHHHHHHCCCCCCEEEEH
ALSKGIDGILLVGCKYGEDYQCHFIRGSELANRRMENVAETLERLMLEKERVQVVEISIN
HHHCCCCEEEEEEEECCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECC
EWDKITEIIDNFVNQIMEIGANPYKGF
CHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MMEKVGVYICTGCDIDKLDIERLKNVAKEEFGIEAKIHPHLCSQEGVEMLKNDAAELDAL
CCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHCCHHHHHEE
VIAACSPRVKTALFTFDDKYVERASLREGVVWSHDIDEHAQELAEDYLRIAITKAQKAEK
EEEECCCCCEEEEEECCHHHHHHHHHHCCCEECCCHHHHHHHHHHHHHHHHHHHHHCCCC
PEPYIEEVSKDILVVGGGVTGLTAALEVAKAGYKAHLVEKEAELGGWVAKYYKTLPVEPP
CCHHHHHCCCCEEEEECCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
YTRIEENPVFQLIDEVKSNGNIEVYTSAEIDSISGQPGMFDVVLNKDGEKVQFRVGGIVV
CCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCEEEEEECCCCCEEEEEECCEEE
ATGWKPYDASALEELGYGKFADVVTNLEFEEMAKEGKILRKSDGSEAKNVVFIQCAGQRD
ECCCCCCCHHHHHHCCCCHHHHHHHCCCHHHHHHCCCEEECCCCCCCCCEEEEEECCCCC
ENHLPYCSSVCCLVSLKQAKYVRELTNGNAFIIYKDMRTPGLWEDFYKEMQQDDGIFLTK
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHCCCCEEEEC
GDIKEIKEEGGKLTVVVTNTLLGEDIAIKADLIVLATGMVSTLKGLYTVKEEFPDEKTVP
CHHHHHHHCCCEEEEEEECCCCCCCEEEECCHHEEHHHHHHHHHHHHHHHHHCCCCCCCC
YKHISEPHLIKSEEDVEVIKQAGHILNLQYRQGPELPTLKYGFPDSNYICFPYESRRLGI
HHHCCCCCCCCCCHHHHHHHHCCCEEEEEECCCCCCCEEEECCCCCCEEEECCCCCEEEE
YAAGAVRAPMEIASCIEDAKGAALKAIQAVELVAEGKTTFPRTGDIDYPQFFLQRCTQCK
EECCCHHCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHH
RCTEECPFGALDEDEKGTPMPNPLRCRRCGICFGACPERIISFKTYSIDQMASAVKSIYV
HHHHHCCCCCCCCCCCCCCCCCCHHHHHHCCCHHCCHHHHHHHCCCCHHHHHHHHHEEEC
PDPNWDEGAEDKFRFIVFACENDALPALDMSALNGKKWSPLARIIPVRCLGSVNTVFIAD
CCCCCCCCCCCCEEEEEEEECCCCCCCCCHHHCCCCCCCCHHHHHHHHHCCCCCCEEEEH
ALSKGIDGILLVGCKYGEDYQCHFIRGSELANRRMENVAETLERLMLEKERVQVVEISIN
HHHCCCCEEEEEEEECCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECC
EWDKITEIIDNFVNQIMEIGANPYKGF
CHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11932238 [H]