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The map label for this gene is hemU-1

Identifier: 11498043

GI number: 11498043

Start: 387991

End: 388995

Strand: Reverse

Name: hemU-1

Synonym: AF0431

Alternate gene names: 11498043

Gene position: 388995-387991 (Counterclockwise)

Preceding gene: 11498044

Following gene: 11498042

Centisome position: 17.86

GC content: 51.64

Gene sequence:

>1005_bases
ATGACCGAATACAGAAGGAGAATAAGAGTTGCTGAACTGCTGCTCCTGAGCTTGCTAATTTTTTCAGTTACTGCATCCCT
TCTCGCAGGCTCATACAGCCTTTCTCCAGCAAAGATTTTCAGCCTAAACTCCCCCGTCATCACCAACATAAGGCTCCCCC
GCATAGTCACAGCCCTGATTGTAGGTGCAAGCCTTGCTGTAAGCGGGGCAGTGATGCAGTGCATACTCAGAAATCCGCTC
GCTTCACCCTTCACGCTCGGCGTTTCGCACGGAGCAGCCTTTGGTGCGGCTTTTGCCATAATCTACCTCGGCGCGGGAAT
GCTCCACAGAACGGGGGAGAGCATAACAATTCTCAACCCCTACCTCGTCCCCTTTTTCGCCTTTCTTGGATCACTCATCA
GCGTTTTTGTAATACTAACGCTCTCAAGAATCAGAAGCTTCACTCCGGAGGCGATGATTCTCACCGGCGTTGCGATGGCC
TCCCTCTTTCAGGCGGCAACAATGCTCATGCAGTACTTCGCTGAGGACGTAATGGTCGCCTCGGTCGTTTTCTGGACGTT
TGGAGATATGGGGAGAACTAACTGGAATGAAATCTACCTGATGGGCGCAATTTTTGCCGTATCGCTGCTCTACTTTATCT
TCAGGCGGATGGACTACAACGCCCTCACTCTCAACGATGAGACTGCAATCTCGCTCGGTGTGAATCCGCAGAGAGTCAGA
CTCGAAGGACTTGTAATCTCATCCCTTCTCACAGCCGTCTGCGTTTCATTTACAGGAATTGTTGGGTTTGTTGGGCTTGT
AGCCCCGCACTCCATAAGAATTGCTGTTAGTGGGGACCACAGGTTCCTTATTCCGCTCAGCACGGTTTTTGGTGCAACGC
TTCTCCTAATTGCGGACACCTTCGGAAGGACTGTGATCAGCCCCGTGATGATTCCAGTTGGCATAGTGACGGCCTTCGTC
GGTGCGCCCATGTTCATTTTCCTCCTCTTGAGAGGCTGGAGGTGA

Upstream 100 bases:

>100_bases
AGGCGGACAAAATCTTCGAGTTCCTCGTTGGCAAAAAGCTTTACGAGCAGATGGCAGAGCACTACGGCGGTTTCAAGAAC
ATTGCAGACGTGTTCGAGAA

Downstream 100 bases:

>100_bases
AAGAATGATTGAAGTCAGGAGCTTATACTACTCCTACAACTCCAAACCCGTTATTCAGGATTTGGAGTTTGAGGCTGAGA
GGGGCGAATTCGTTTTCATT

Product: iron (III) ABC transporter, permease protein (hemU-1)

Products: ADP; phosphate; cob(I)alamin [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 334; Mature: 333

Protein sequence:

>334_residues
MTEYRRRIRVAELLLLSLLIFSVTASLLAGSYSLSPAKIFSLNSPVITNIRLPRIVTALIVGASLAVSGAVMQCILRNPL
ASPFTLGVSHGAAFGAAFAIIYLGAGMLHRTGESITILNPYLVPFFAFLGSLISVFVILTLSRIRSFTPEAMILTGVAMA
SLFQAATMLMQYFAEDVMVASVVFWTFGDMGRTNWNEIYLMGAIFAVSLLYFIFRRMDYNALTLNDETAISLGVNPQRVR
LEGLVISSLLTAVCVSFTGIVGFVGLVAPHSIRIAVSGDHRFLIPLSTVFGATLLLIADTFGRTVISPVMIPVGIVTAFV
GAPMFIFLLLRGWR

Sequences:

>Translated_334_residues
MTEYRRRIRVAELLLLSLLIFSVTASLLAGSYSLSPAKIFSLNSPVITNIRLPRIVTALIVGASLAVSGAVMQCILRNPL
ASPFTLGVSHGAAFGAAFAIIYLGAGMLHRTGESITILNPYLVPFFAFLGSLISVFVILTLSRIRSFTPEAMILTGVAMA
SLFQAATMLMQYFAEDVMVASVVFWTFGDMGRTNWNEIYLMGAIFAVSLLYFIFRRMDYNALTLNDETAISLGVNPQRVR
LEGLVISSLLTAVCVSFTGIVGFVGLVAPHSIRIAVSGDHRFLIPLSTVFGATLLLIADTFGRTVISPVMIPVGIVTAFV
GAPMFIFLLLRGWR
>Mature_333_residues
TEYRRRIRVAELLLLSLLIFSVTASLLAGSYSLSPAKIFSLNSPVITNIRLPRIVTALIVGASLAVSGAVMQCILRNPLA
SPFTLGVSHGAAFGAAFAIIYLGAGMLHRTGESITILNPYLVPFFAFLGSLISVFVILTLSRIRSFTPEAMILTGVAMAS
LFQAATMLMQYFAEDVMVASVVFWTFGDMGRTNWNEIYLMGAIFAVSLLYFIFRRMDYNALTLNDETAISLGVNPQRVRL
EGLVISSLLTAVCVSFTGIVGFVGLVAPHSIRIAVSGDHRFLIPLSTVFGATLLLIADTFGRTVISPVMIPVGIVTAFVG
APMFIFLLLRGWR

Specific function: Probably part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788004, Length=304, Percent_Identity=35.1973684210526, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI1790741, Length=319, Percent_Identity=31.3479623824451, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1790740, Length=288, Percent_Identity=34.375, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1786347, Length=291, Percent_Identity=32.3024054982818, Blast_Score=114, Evalue=9e-27,
Organism=Escherichia coli, GI1786805, Length=325, Percent_Identity=34.1538461538462, Blast_Score=111, Evalue=6e-26,
Organism=Escherichia coli, GI1786804, Length=343, Percent_Identity=28.5714285714286, Blast_Score=102, Evalue=4e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 36175; Mature: 36044

Theoretical pI: Translated: 10.07; Mature: 10.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEYRRRIRVAELLLLSLLIFSVTASLLAGSYSLSPAKIFSLNSPVITNIRLPRIVTALI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCEECCCHHHHHHHHH
VGASLAVSGAVMQCILRNPLASPFTLGVSHGAAFGAAFAIIYLGAGMLHRTGESITILNP
HHHHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHCHHHHHCCCEEEEECH
YLVPFFAFLGSLISVFVILTLSRIRSFTPEAMILTGVAMASLFQAATMLMQYFAEDVMVA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVVFWTFGDMGRTNWNEIYLMGAIFAVSLLYFIFRRMDYNALTLNDETAISLGVNPQRVR
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCEEEECCCCHHHH
LEGLVISSLLTAVCVSFTGIVGFVGLVAPHSIRIAVSGDHRFLIPLSTVFGATLLLIADT
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCEEEEEHHHHHHHHHHHHHHH
FGRTVISPVMIPVGIVTAFVGAPMFIFLLLRGWR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TEYRRRIRVAELLLLSLLIFSVTASLLAGSYSLSPAKIFSLNSPVITNIRLPRIVTALI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCEECCCHHHHHHHHH
VGASLAVSGAVMQCILRNPLASPFTLGVSHGAAFGAAFAIIYLGAGMLHRTGESITILNP
HHHHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHCHHHHHCCCEEEEECH
YLVPFFAFLGSLISVFVILTLSRIRSFTPEAMILTGVAMASLFQAATMLMQYFAEDVMVA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVVFWTFGDMGRTNWNEIYLMGAIFAVSLLYFIFRRMDYNALTLNDETAISLGVNPQRVR
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCEEEECCCCHHHH
LEGLVISSLLTAVCVSFTGIVGFVGLVAPHSIRIAVSGDHRFLIPLSTVFGATLLLIADT
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCEEEEEHHHHHHHHHHHHHHH
FGRTVISPVMIPVGIVTAFVGAPMFIFLLLRGWR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; cob(I)alamin [Periplasm]; H2O [C]

Specific reaction: ATP + cob(I)alamin [Periplasm] + H2O = ADP + phosphate + cob(I)alamin [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]